Research output per year
Research output per year
- 1 - 50 out of 180 results
Search results
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2024
Balancing at the edge of excitability: implications for cell movement
Biswas, D., Banerjee, P. & Iglesias, P. A., Mar 2024, In: Mathematics of Control, Signals, and Systems. 36, 1, p. 121-137 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Actuation of single downstream nodes in growth factor network steers immune cell migration
Pal, D. S., Banerjee, T., Lin, Y., de Trogoff, F., Borleis, J., Iglesias, P. A. & Devreotes, P. N., Jul 10 2023, In: Developmental Cell. 58, 13, p. 1170-1188.e7Research output: Contribution to journal › Article › peer-review
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A dynamic partitioning mechanism polarizes membrane protein distribution
Banerjee, T., Matsuoka, S., Biswas, D., Miao, Y., Pal, D. S., Kamimura, Y., Ueda, M., Devreotes, P. N. & Iglesias, P. A., Dec 2023, In: Nature communications. 14, 1, 7909.Research output: Contribution to journal › Article › peer-review
Open Access -
Decoding Angiotensin Receptors: TOMAHAQ-Based Detection and Quantification of Angiotensin Type-1 and Type-2 Receptors
Cosarderelioglu, C., Kreimer, S., Plaza-Rodriguez, A. I., Iglesias, P. A., Talbot, C. C., Siragy, H. M., Carey, R. M., Ubaida-Mohien, C., O’rourke, B., Ferrucci, L., Bennett, D. A., Walston, J. & Abadir, P., Sep 19 2023, In: Journal of the American Heart Association. 12, 18, e030791.Research output: Contribution to journal › Article › peer-review
Open Access -
Enhanced chemotaxis through spatially regulated absolute concentration robustness
Biswas, D., Bhattacharya, S. & Iglesias, P. A., Jun 2023, In: International Journal of Robust and Nonlinear Control. 33, 9, p. 4923-4944 22 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Nanotopography modulates intracellular excitable systems through cytoskeleton actuation
Yang, Q., Miao, Y., Banerjee, P., Hourwitz, M. J., Hu, M., Qing, Q., Iglesias, P. A., Fourkas, J. T., Losert, W. & Devreotes, P. N., May 9 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 19, e2218906120.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Dynamics of Gradient Sensing and Chemotaxis
Iglesias, P. A., Jan 1 2022, Encyclopedia of Cell Biology: Volume 1-6, Second Edition. Elsevier, Vol. 6. p. 152-158 7 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Particle-based model of mechanosensory contractility kit assembly
Plaza-Rodríguez, A. I., Nguyen, L. T. S., Robinson, D. N. & Iglesias, P. A., Dec 6 2022, In: Biophysical journal. 121, 23, p. 4600-4614 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Spatiotemporal dynamics of membrane surface charge regulates cell polarity and migration
Banerjee, T., Biswas, D., Pal, D. S., Miao, Y., Iglesias, P. A. & Devreotes, P. N., Oct 2022, In: Nature cell biology. 24, 10, p. 1499-1515 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Adenine nucleotide translocase regulates airway epithelial metabolism, surface hydration and ciliary function
Kliment, C. R., Nguyen, J. M. K., Kaltreider, M. J., Lu, Y. W., Claypool, S. M., Radder, J. E., Sciurba, F. C., Zhang, Y., Gregory, A. D., Iglesias, P. A., Sidhaye, V. K. & Robinson, D. N., Feb 2021, In: Journal of cell science. 134, 4, jcs257162.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A mesoscale mechanical model of cellular interactions
DiNapoli, K. T., Robinson, D. N. & Iglesias, P. A., Nov 16 2021, In: Biophysical journal. 120, 22, p. 4905-4917 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Deciphering cell signaling networks with massively multiplexed biosensor barcoding
Yang, J. M., Chi, W. Y., Liang, J., Takayanagi, S., Iglesias, P. A. & Huang, C. H., Dec 9 2021, In: Cell. 184, 25, p. 6193-6206.e14Research output: Contribution to journal › Article › peer-review
Open Access -
On the role of p53 in the cellular response to aneuploidy
Narkar, A., Johnson, B. A., Bharne, P., Zhu, J., Padmanaban, V., Biswas, D., Fraser, A., Iglesias, P. A., Ewald, A. J. & Li, R., Mar 23 2021, In: Cell Reports. 34, 12, 108892.Research output: Contribution to journal › Article › peer-review
Open Access -
Reverse fountain flow of phosphatidylinositol-3,4-bisphosphate polarizes migrating cells
Li, X., Pal, D. S., Biswas, D., Iglesias, P. A. & Devreotes, P. N., Feb 15 2021, In: EMBO Journal. 40, 4, e105094.Research output: Contribution to journal › Article › peer-review
Open Access -
Sensitivity minimization, biological homeostasis and information theory
Biswas, D. & Iglesias, P. A., Feb 2021, In: Biological Cybernetics. 115, 1, p. 103-113 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The impact of a closed-loop thalamocortical model on the spatiotemporal dynamics of cortical and thalamic traveling waves
Bhattacharya, S., Cauchois, M. B. L., Iglesias, P. A. & Chen, Z. S., Dec 2021, In: Scientific reports. 11, 1, 14359.Research output: Contribution to journal › Article › peer-review
Open Access -
Three-dimensional stochastic simulation of chemoattractant-mediated excitability in cells
Biswas, D., Devreotes, P. N. & Iglesias, P. A., Jul 2021, In: PLoS computational biology. 17, 7 July, e1008803.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells
Zhan, H., Bhattacharya, S., Cai, H., Iglesias, P. A., Huang, C. H. & Devreotes, P. N., Sep 14 2020, In: Developmental Cell. 54, 5, p. 608-623.e5Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Tools for computational analysis of moving boundary problems in cellular mechanobiology
DiNapoli, K. T., Robinson, D. N. & Iglesias, P. A., 2020, (Accepted/In press) In: Wiley Interdisciplinary Reviews: Systems Biology and Medicine.Research output: Contribution to journal › Review article › peer-review
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Traveling and standing waves mediate pattern formation in cellular protrusions
Bhattacharya, S., Banerjee, T., Miao, Y., Zhan, H., Devreotes, P. N. & Iglesias, P. A., Aug 2020, In: Science Advances. 6, 32, eaay7682.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
2019
Controlling excitable wave behaviors through the tuning of three parameters
Bhattacharya, S. & Iglesias, P. A., Apr 1 2019, In: Biological Cybernetics. 113, 1-2, p. 61-70 10 p.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations -
Control theory in biology and medicine: Introduction to the special issue
Thomas, P. J., Olufsen, M., Sepulchre, R., Iglesias, P. A., Ijspeert, A. & Srinivasan, M., Apr 1 2019, In: Biological Cybernetics. 113, 1-2Research output: Contribution to journal › Editorial › peer-review
Open Access3 Scopus citations -
Erratum: Publisher Correction: Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation (Nature communications (2018) 9 1 (4673))
Yang, J. M., Bhattacharya, S., West-Foyle, H., Hung, C. F., Wu, T. C., Iglesias, P. A. & Huang, C. H., Jan 15 2019, In: Nature communications. 10, 1, p. 319 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Erratum to: Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation (Nature Communications, (2018), 9, 1, (4673), 10.1038/s41467-018-07150-9)
Yang, J. M., Bhattacharya, S., West-Foyle, H., Hung, C. F., Wu, T. C., Iglesias, P. A. & Huang, C. H., Dec 1 2019, In: Nature communications. 10, 1, 319.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
How the mechanobiome drives cell behavior, viewed through the lens of control theory
Kothari, P., Johnson, C., Sandone, C., Iglesias, P. A. & Robinson, D. N., Sep 2019, In: Journal of cell science. 132, 17, jcs234476.Research output: Contribution to journal › Review article › peer-review
Open Access10 Scopus citations -
Myosin IIB assembly state determines its mechanosensitive dynamics
Schiffhauer, E. S., Ren, Y., Iglesias, V. A., Kothari, P., Iglesias, P. A. & Robinson, D. N., Mar 1 2019, In: Journal of Cell Biology. 218, 3, p. 895-908 14 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Targeting mechanoresponsive proteins in pancreatic cancer: 4-hydroxyacetophenone blocks dissemination and invasion by activating MYH14
Surcel, A., Schiffhauer, E. S., Thomas, D. G., Zhu, Q., DiNapoli, K. T., Herbig, M., Otto, O., West-Foyle, H., Jacobi, A., Krater, M., Plak, K., Guck, J., Jaffee, E. M., Iglesias, P. A., Anders, R. A. & Robinson, D. N., Sep 15 2019, In: Cancer Research. 79, 18, p. 4665-4678 14 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Wave patterns organize cellular protrusions and control cortical dynamics
Miao, Y., Bhattacharya, S., Banerjee, T., Abubaker-Sharif, B., Long, Y., Inoue, T., Iglesias, P. A. & Devreotes, P. N., Mar 2019, In: Molecular systems biology. 15, 3, e8585.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2018
Control of Chemotaxis Through Absolute Concentration Robustness
Bhattacharya, S., Biswas, D., Enciso, G. A. & Iglesias, P. A., Jul 2 2018, 2018 IEEE Conference on Decision and Control, CDC 2018. Institute of Electrical and Electronics Engineers Inc., p. 4360-4365 6 p. 8619195. (Proceedings of the IEEE Conference on Decision and Control; vol. 2018-December).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
1 Scopus citations -
Correction: Chemical and mechanical stimuli act on common signal transduction and cytoskeletal networks(Proc Natl Acad Sci USA (2018) 113 (E7500-E7509) DOI: 10.1073/pnas.1608767113)
Artemenko, Y., Axiotakis, L., Borleis, J. & Iglesias, P. A., Jul 10 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 28, p. E6669Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation
Yang, J. M., Bhattacharya, S., West-Foyle, H., Hung, C. F., Wu, T. C., Iglesias, P. A. & Huang, C. H., Dec 1 2018, In: Nature communications. 9, 1, 4673.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Mutually inhibitory Ras-PI(3,4)P2 feedback loops mediate cell migration
Li, X., Edwards, M., Swaney, K. F., Singh, N., Bhattacharya, S., Borleis, J., Long, Y., Iglesias, P. A., Chen, J. & Devreotes, P. N., Sep 25 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 39, p. E9125-E9134Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
The threshold of an excitable system serves as a control mechanism for noise filtering during chemotaxis
Bhattacharya, S. & Iglesias, P. A., Jul 2018, In: PloS one. 13, 7, e0201283.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2017
Altering the threshold of an excitable signal transduction network changes cell migratory modes
Miao, Y., Bhattacharya, S., Edwards, M., Cai, H., Inoue, T., Iglesias, P. A. & Devreotes, P. N., 2017, In: Nature cell biology. 19, 4, p. 329-340 12 p.Research output: Contribution to journal › Article › peer-review
Open Access50 Scopus citations -
Excitable signal transduction networks in directed cell migration
Devreotes, P. N., Bhattacharya, S., Edwards, M., Iglesias, P. A., Lampert, T. & Miao, Y., Oct 6 2017, In: Annual Review of Cell and Developmental Biology. 33, p. 103-125 23 p.Research output: Contribution to journal › Article › peer-review
Open Access67 Scopus citations -
Sphingolipids facilitate age asymmetry of membrane proteins in dividing yeast cells
Singh, P., Ramachandran, S. K., Zhu, J., Kim, B. C., Biswas, D., Ha, T., Iglesias, P. A. & Li, R., Oct 1 2017, In: Molecular biology of the cell. 28, 20, p. 2712-2722 11 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
The triggering, curving and stopping of excitable waves during cell migration
Bhattacharya, S. & Iglesias, P. A., May 10 2017, 2017 51st Annual Conference on Information Sciences and Systems, CISS 2017. Institute of Electrical and Electronics Engineers Inc., 7926103. (2017 51st Annual Conference on Information Sciences and Systems, CISS 2017).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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2016
Chemical and mechanical stimuli act on common signal transduction and cytoskeletal networks
Artemenko, Y., Axiotakis, L., Borleis, J., Iglesias, P. A. & Devreotes, P. N., Nov 22 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 47, p. E7500-E7509Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Cytokinesis: Robust cell shape regulation
Srivastava, V., Iglesias, P. A. & Robinson, D. N., May 1 2016, In: Seminars in Cell and Developmental Biology. 53, p. 39-44 6 p.Research output: Contribution to journal › Review article › peer-review
Open Access15 Scopus citations -
Dynamics of Gradient Sensing and Chemotaxis
Iglesias, P. A., Jan 1 2016, Systems Cell Biology. Elsevier Inc., Vol. 4. p. 4-9 6 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
2 Scopus citations -
Endoplasmic reticulum lipid flux influences enterocyte nuclear morphology and lipid-dependent transcriptional responses
Zeituni, E. M., Wilson, M. H., Zheng, X., Iglesias, P. A., Sepanski, M. A., Siddiqi, M. A., Anderson, J. L., Zheng, Y. & Farber, S. A., Nov 4 2016, In: Journal of Biological Chemistry. 291, 45, p. 23804-23816 13 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Mechanoaccumulative Elements of the Mammalian Actin Cytoskeleton
Schiffhauer, ES. S., Luo, T., Mohan, K., Srivastava, V., Qian, X., Griffis, ER. R., Iglesias, PA. A. & Robinson, DN. N., 2016, In: Current Biology. 26, 11, p. 1473-1479 7 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Modeling excitable dynamics of chemotactic networks
Bhattacharya, S. & Iglesias, P. A., 2016, Methods in Molecular Biology. Humana Press Inc., Vol. 1407. p. 397-415 19 p. (Methods in Molecular Biology; vol. 1407).Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
The Regulation of Cell Motility Through an Excitable Network
Bhattacharya, S. & Iglesias, P. A., 2016, In: Foundations of Systems Biology in Engineering - FOSBE 2016: Magdeburg, Germany, 9—12 October 2016. 49, 26, p. 357-363 7 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
The Use of Rate Distortion Theory to Evaluate Biological Signaling Pathways
Iglesias, P. A., Jun 2016, In: IEEE Transactions on Molecular, Biological, and Multi-Scale Communications. 2, 1, p. 31-39 9 p., 7728150.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
2015
Cell shape regulation through mechanosensory feedback control
Mohan, K., Luo, T., Robinson, D. N. & Iglesias, P. A., Aug 6 2015, In: Journal of the Royal Society Interface. 12, 109, 20150512.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Novel protein Callipygian defines the back of migrating cells
Swaney, K. F., Borleis, J., Iglesias, P. A. & Devreotes, P. N., Jul 21 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 29, p. E3845-E3854Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2014
A computational model for the formation of lamin-B mitotic spindle envelope and matrix
Shi, C., Channels, W. E., Zheng, Y. & Iglesias, P. A., 2014, In: Interface Focus. 4, 3Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Cell memory and adaptation in chemotaxis
Huang, C. H. & Iglesias, P. A., Oct 28 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 43, p. 15287-15288 2 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access7 Scopus citations -
Comparison of adaptation motifs: Temporal, stochastic and spatial responses
Iglesias, P. A. & Shi, C., Dec 1 2014, In: IET Systems Biology. 8, 6, p. 268-281 14 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations