Research Output 1997 2018

2018

Automated diagnosis of colon cancer using hyperspectral sensing

Beaulieu, R. J., Goldstein, S. D., Singh, J., Safar, B., Banerjee, A. & Ahuja, N. Jan 1 2018 (Accepted/In press) In : International Journal of Medical Robotics and Computer Assisted Surgery.

Research output: Contribution to journalArticle

Colonic Neoplasms
Tumors
Colorectal Neoplasms
Neoplasms
Spectrum analysis

DNA Methylation Patterns Separate Senescence from Transformation Potential and Indicate Cancer Risk

Xie, W., Kagiampakis, I., Pan, L., Zhang, Y. W., Murphy, L., Tao, Y., Kong, X., Kang, B., Xia, L., Carvalho, F. L. F., Sen, S., Chiu Yen, R. W., Zahnow, C. A., Ahuja, N., Baylin, S. B. & Easwaran, H. Feb 12 2018 In : Cancer cell. 33, 2, p. 309-321.e5

Research output: Contribution to journalArticle

DNA Methylation
Methylation
Developmental Genes
Neoplasms
Epigenomics

Introduction to the Special Edition of Annals of Surgery: The Johns Hopkins Festschrift

Wolfgang, C. L., Efron, D. T., Ahuja, N. & Lillemoe, K. D. Feb 1 2018 In : Annals of Surgery. 267, 2S, p. S1

Research output: Contribution to journalEditorial

Treatment with epigenetic agents profoundly inhibits tumor growth in leiomyosarcoma

Fischer, C. D. C., Hu, Y., Morreale, M., Lin, W. Y., Wali, A., Thakar, M., Karunasena, E., Sen, R., Cai, Y., Murphy, L., Zahnow, C. A., Keer, H., Thakar, M. & Ahuja, N. Apr 10 2018 In : Oncotarget. 9, 27, p. 19379-19395 17 p.

Research output: Contribution to journalArticle

Leiomyosarcoma
Epigenomics
Azacitidine
Growth
Neoplasms
2017

A four-gene promoter methylation marker panel consisting of GREM1, NEURL, LAD1, and NEFH predicts survival of clear cell renal cell cancer patients

Van Vlodrop, I. J. H., Joosten, S. C., De Meyer, T., Smits, K. M., Van Neste, L., Melotte, V., Baldewijns, M. M. L. L., Schouten, L. J., Van Den Brandt, P. A., Jeschke, J., Yi, J. M., Schuebel, K. E., Ahuja, N., Herman, J. G., Aarts, M. J., Bosman, F. T., Van Criekinge, W. & Van Engeland, M. Apr 15 2017 In : Clinical Cancer Research. 23, 8, p. 2006-2018 13 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Methylation
Cell Survival
Genes
Confidence Intervals

A novel approach for selecting combination clinical markers of pathology applied to a large retrospective cohort of surgically resected pancreatic cysts

Masica, D. L. , Molin, M. D. , Wolfgang, C. L. , Tomita, T. , Ostovaneh, M. R. , Blackford, A. , Moran, R. A. , Law, J. K. , Barkley, T. , Goggins, M. , Canto, M. I. , Pittman, M. , Eshleman, J. R. , Ali, S. Z. , Fishman, E. K. , Kamel, I. R. , Raman, S. P. , Zaheer, A. , Ahuja, N. , Makary, M. A. & 16 others Weiss, M. J., Hirose, K., Cameron, J. L., Rezaee, N., He, J., Ahn, Y. J., Wu, W., Wang, Y., Springer, S., Diaz, L. L., Papadopoulos, N., Hruban, R. H., Kinzler, K. W., Vogelstein, B., Karchin, R. & Lennon, A. M. 2017 In : Journal of the American Medical Informatics Association. 24, 1, p. 145-152 8 p.

Research output: Contribution to journalArticle

Pancreatic Cyst
Clinical Pathology
Biomarkers
Sensitivity and Specificity
Serous Cystadenoma

Can echogenic appearance of neuroendocrine liver metastases on intraoperative ultrasonography predict tumor biology and prognosis?

Dogeas, E., Chong, C. C. N., Weiss, M. J., Ahuja, N. & Choti, M. A. Jan 1 2017 (Accepted/In press) In : HPB.

Research output: Contribution to journalArticle

Ultrasonography
Neoplasm Metastasis
Liver
Neoplasms
Neuroendocrine Tumors
Pancreatic Neoplasms
Epithelial Cells
Keratins
Neoplasms
Pancreas

Combination epigenetic therapy in advanced breast cancer with 5-azacitidine and entinostat: A phase II national cancer institute/stand up to cancer study

Connolly, R. M. , Li, H. , Jankowitz, R. C. , Zhang, Z. , Rudek, M. A. , Jeter, S. C. , Slater, S. A. , Powers, P. , Wolff, A. C. , Fetting, J. H. , Brufsky, A. , Piekarz, R. , Ahuja, N. , Laird, P. W. , Shen, H. , Weisenberger, D. J. , Cope, L. , Herman, J. G. , Somlo, G. , Garcia, A. A. & 5 others Jones, P. A., Baylin, S. B., Davidson, N. E., Zahnow, C. A. & Stearns, V. Jun 1 2017 In : Clinical Cancer Research. 23, 11, p. 2691-2701 11 p.

Research output: Contribution to journalArticle

Azacitidine
National Cancer Institute (U.S.)
Epigenomics
Breast Neoplasms
Triple Negative Breast Neoplasms

Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat; a phase 2 consortium/stand Up 2 cancer study

Azad, N. S. , El-Khoueiry, A. , Yin, J. , Oberg, A. L. , Flynn, P. , Adkins, D. , Sharma, A. , Weisenberger, D. J. , Brown, T. , Medvari, P. , Jones, P. A. , Easwaran, H. , Kamel, I. , Bahary, N. , Kim, G. , Picus, J. , Pitot, H. C. , Erlichman, C. , Donehower, R. , Shen, H. & 4 others Laird, P. W., Piekarz, R., Baylin, S. & Ahuja, N. 2017 In : Oncotarget. 8, 21, p. 35326-35338 13 p.

Research output: Contribution to journalArticle

Azacitidine
Epigenomics
Colorectal Neoplasms
Neoplasms
Therapeutics

Differential expression of hENT1 and hENT2 in colon cancer cell lines

Liu, Y., Zuo, T., Zhu, X., Ahuja, N. & Fu, T. Feb 16 2017 In : Genetics and Molecular Research. 16, 1, gmr16019549

Research output: Contribution to journalArticle

Colonic Neoplasms
Cell Line
Nucleosides
Colorectal Neoplasms
Pharmaceutical Preparations

Epigenetically altered miR-1247 functions as a tumor suppressor in pancreatic cancer

Yi, J. M., Eun-Jin, Hyun-Mi, Bae, J. H., Kang, K., Ahuja, N. & Yang, K. 2017 In : Oncotarget. 8, 16, p. 26600-26612 13 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Chromosomes, Human, Pair 2
MicroRNAs
CpG Islands
Neoplasms

Epigenetic therapy and chemosensitization in solid malignancy

Ronnekleiv-Kelly, S. M., Sharma, A. & Ahuja, N. Apr 1 2017 In : Cancer Treatment Reviews. 55, p. 200-208 9 p.

Research output: Contribution to journalReview article

Epigenomics
Neoplasms
Therapeutics
Breast Neoplasms
Histone Deacetylase Inhibitors

Esophageal distensibility measurement: impact on clinical management and procedure length

Ahuja, N. K., Agnihotri, A., Lynch, K. L., Hoo-Fatt, D., Onyimba, F., McKnight, M., Okeke, F. C., Garcia, P., Dhalla, S., Stein, E., Pasricha, P. J. & Clarke, J. O. Aug 1 2017 In : Diseases of the Esophagus. 30, 8, p. 1-8 8 p.

Research output: Contribution to journalArticle

Deglutition Disorders
Eosinophilic Esophagitis
Fundoplication
Esophageal Achalasia
Connective Tissue Diseases

Hypomethylating agents synergize with irinotecan to improve response to chemotherapy in colorectal cancer cells

Sharma, A., Vatapalli, R., Abdelfatah, E., McMahon, K. W., Kerner, Z., Guzzetta, A. A., Singh, J., Zahnow, C., Baylin, S. B., Yerram, S., Hu, Y., Azad, N. & Ahuja, N. Apr 1 2017 In : PLoS ONE. 12, 4, e0176139

Research output: Contribution to journalArticle

irinotecan
Chemotherapy
colorectal neoplasms
drug therapy
Colorectal Neoplasms

Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells

Siebenkäs, C., Chiappinelli, K. B., Guzzetta, A. A., Sharma, A., Jeschke, J., Vatapalli, R., Baylin, S. B. & Ahuja, N. Jun 1 2017 In : PLoS ONE. 12, 6, e0179501

Research output: Contribution to journalArticle

ovarian neoplasms
Testicular Neoplasms
Antigen Presentation
DNA methylation
DNA Methylation

Locally advanced primary recto-sigmoid cancers: Improved survival with multivisceral resection

Laurence, G., Ahuja, V., Bell, T., Grim, R. & Ahuja, N. Sep 1 2017 In : American Journal of Surgery. 214, 3, p. 432-436 5 p.

Research output: Contribution to journalArticle

Sigmoid Neoplasms
Survival
Colorectal Neoplasms
Radiation
Kaplan-Meier Estimate

Long-term survival benefit of upfront chemotherapy in patients with newly diagnosed borderline resectable pancreatic cancer

Shrestha, B. , Sun, Y. , Faisal, F. , Kim, V. , Soares, K. , Blair, A. , Herman, J. M. , Narang, A. , Dholakia, A. S. , Rosati, L. , Hacker-Prietz, A. , Chen, L. , Laheru, D. A. , De Jesus-Acosta, A. , Le, D. T. , Donehower, R. , Azad, N. , Diaz, L. A. , Murphy, A. , Lee, V. & 11 others Fishman, E. K., Hruban, R. H., Liang, T., Cameron, J. L., Makary, M., Weiss, M. J., Ahuja, N., He, J., Wolfgang, C. L., Huang, C. Y. & Zheng, L. Jul 1 2017 In : Cancer Medicine. 6, 7, p. 1552-1562 11 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Drug Therapy
Neoadjuvant Therapy
Survival
Adenocarcinoma

Postoperative complications following intraoperative radiotherapy in abdominopelvic malignancy: A single institution analysis of 113 consecutive patients

Abdelfatah, E., Page, A., Sacks, J., Pierorazio, P., Bivalacqua, T., Efron, J., Terezakis, S., Gearhart, S., Fang, S., Safar, B., Pawlik, T. M., Armour, E., Hacker-Prietz, A., Herman, J. & Ahuja, N. Jun 1 2017 In : Journal of Surgical Oncology. 115, 7, p. 883-890 8 p.

Research output: Contribution to journalArticle

Radiotherapy
Neoplasms
Research Ethics Committees
Brachytherapy
Sarcoma

The independent effect of cancer on outcomes: A potential limitation of surgical risk prediction

Leeds, I. L., Canner, J. K., Efron, J. E., Ahuja, N., Haut, E. R., Wick, E. C. & Johnston, F. M. 2017 (Accepted/In press) In : Journal of Surgical Research.

Research output: Contribution to journalArticle

Neoplasms
Quality Improvement
Mortality
Anatomic Models
Gastrointestinal Neoplasms

The Roles of DNA Methylation in the Stages of Cancer

McMahon, K. W., Karunasena, E. & Ahuja, N. Sep 1 2017 In : Cancer Journal (United States). 23, 5, p. 257-261 5 p.

Research output: Contribution to journalReview article

DNA Methylation
Epigenomics
Neoplasms
Biological Phenomena
Biomarkers

What is the clinical significance of esophagogastric junction outflow obstruction? evaluation of 60 patients at a tertiary referral center

Okeke, F. C., Raja, S., Lynch, K. L., Dhalla, S., Nandwani, M., Stein, E. M., Chander Roland, B., Khashab, M. A., Saxena, P., Kumbhari, V., Ahuja, N. K. & Clarke, J. O. Jun 1 2017 In : Neurogastroenterology and Motility. 29, 6, e13061

Research output: Contribution to journalArticle

Esophagogastric Junction
Tertiary Care Centers
Deglutition Disorders
Digestive System Endoscopy
Hiatal Hernia
2016

A Contemporary Evaluation of the Cause of Death and Long-Term Quality of Life After Total Pancreatectomy

Wu, W., Dodson, R., Makary, M. A., Weiss, M. J., Hirose, K., Cameron, J. L., Ahuja, N., Pawlik, T. M., Wolfgang, C. L. & He, J. May 13 2016 (Accepted/In press) In : World Journal of Surgery. p. 1-6 6 p.

Research output: Contribution to journalArticle

Pancreatectomy
Cause of Death
Quality of Life
Diabetes Complications
Insulin

Circulating Tumor Cell Phenotype Predicts Recurrence and Survival in Pancreatic Adenocarcinoma

Poruk, K. E., Valero, V., Saunders, T., Blackford, A. L., Griffin, J. F., Poling, J., Hruban, R. H., Anders, R. A., Herman, J., Zheng, L., Rasheed, Z. A., Laheru, D. A., Ahuja, N., Weiss, M. J., Cameron, J. L., Goggins, M., Iacobuzio-Donahue, C. A., Wood, L. D. & Wolfgang, C. L. Jan 7 2016 (Accepted/In press) In : Annals of Surgery.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Adenocarcinoma
Phenotype
Recurrence
Survival

Combining epigenetic and immunotherapy to combat cancer

Chiappinelli, K. B., Zahnow, C. A., Ahuja, N. & Bylin, S. B. Apr 1 2016 In : Cancer Research. 76, 7, p. 1683-1689 7 p.

Research output: Contribution to journalArticle

Epigenomics
Immunotherapy
Methyltransferases
Melanoma
Neoplasms

DNA methylation changes in extracellular remodeling pathway genes during the transformation of human mesenchymal stem cells

Kim, T. O., Park, S. H., Kim, H. S., Ahuja, N. & Yi, J. M. Mar 31 2016 (Accepted/In press) In : Genes and Genomics. p. 1-7 7 p.

Research output: Contribution to journalArticle

DNA Methylation
Stem cells
Mesenchymal Stromal Cells
Extracellular Matrix
Genes

Epigenetic therapeutics: A new weapon in the war against cancer

Ahuja, N., Sharma, A. R. & Baylin, S. B. Jan 14 2016 In : Annual Review of Medicine. 67, p. 73-89 17 p.

Research output: Contribution to journalArticle

Gene encoding
Weapons
Nucleosomes
Epigenomics
Gene expression

Epigenetic therapy in gastrointestinal cancer: The right combination

Abdelfatah, E., Kerner, Z., Nanda, N. & Ahuja, N. Jul 1 2016 In : Therapeutic Advances in Gastroenterology. 9, 4, p. 560-579 20 p.

Research output: Contribution to journalReview article

Gastrointestinal Neoplasms
Epigenomics
Therapeutics
Neoplasms
Pharmaceutical Preparations

Gastric and small intestine gastrointestinal stromal tumors: Do outcomes differ?

Giuliano, K., Nagarajan, N., Canner, J., Najafian, A., Wolfgang, C., Schneider, E., Meyer, C., Lennon, A. M., Johnston, F. M. & Ahuja, N. 2016 (Accepted/In press) In : Journal of Surgical Oncology.

Research output: Contribution to journalArticle

Gastrointestinal Stromal Tumors
Small Intestine
Stomach
Mortality
Survival Analysis

IGFBP-3 gene methylation in primary tumor predicts recurrence of stage II colorectal cancers

Fu, T., Pappou, E. P., Guzzetta, A. A., De Freitas Calmon, M., Sun, L., Herrera, A., Li, F., Wolfgang, C. L., Baylin, S. B., Iacobuzio-Donahue, C. A., Tong, W. & Ahuja, N. 2016 In : Annals of Surgery. 263, 2, p. 337-344 8 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 3
Methylation
Colorectal Neoplasms
Recurrence
Genes
Adenocarcinoma
Neoplasms
Survival
Pancreatic Neoplasms

Long-term outcomes in treatment of retroperitoneal sarcomas: A 15 year single-institution evaluation of prognostic features

Abdelfatah, E., Guzzetta, A. A., Nagarajan, N., Wolfgang, C. L., Pawlik, T. M., Choti, M. A., Schulick, R., Montgomery, E. A., Meyer, C., Thornton, K., Herman, J., Terezakis, S., Frassica, D. & Ahuja, N. Jul 1 2016 In : Journal of Surgical Oncology. 114, 1, p. 56-64 9 p.

Research output: Contribution to journalArticle

Sarcoma
Recurrence
Radiotherapy
Survival
Liposarcoma

Methylation of MGMT Is Associated with poor prognosis in patients with stage III duodenal adenocarcinoma

Fu, T., Sharmab, A., Xie, F., Liu, Y., Li, K., Wan, W., Baylin, S. B., Lwolfgang, C. & Ahuja, N. Sep 1 2016 In : PLoS One. 11, 9, e0162929

Research output: Contribution to journalArticle

Methylation
methyltransferases
Methyltransferases
DNA methylation
DNA Methylation

Neutrophil-to-lymphocyte Ratio is a Predictive Marker for Invasive Malignancy in Intraductal Papillary Mucinous Neoplasms of the Pancreas

Gemenetzis, G., Bagante, F., Griffin, J. F., Rezaee, N., Javed, A. A., Manos, L. L., Lennon, A. M., Wood, L. D., Hruban, R. H., Zheng, L., Zaheer, A., Fishman, E. K., Ahuja, N., Cameron, J. L., Weiss, M. J., He, J. & Wolfgang, C. L. Sep 14 2016 (Accepted/In press) In : Annals of Surgery.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Neutrophils
Lymphocytes
Neoplasms
Carcinoma

Patterns of PD-L1 expression and CD8 T cell infiltration in gastric adenocarcinomas and associated immune stroma

Thompson, E. D., Zahurak, M., Murphy, A., Cornish, T., Cuka, N., Abdelfatah, E., Yang, S., Duncan, M., Ahuja, N., Taube, J. M., Anders, R. A. & Kelly, R. J. Jan 22 2016 (Accepted/In press) In : Gut.

Research output: Contribution to journalArticle

Stomach
Adenocarcinoma
Ligands
T-Lymphocytes
Esophagogastric Junction

Predictors of improved survival for patients with retroperitoneal sarcoma

Giuliano, K., Nagarajan, N., Canner, J. K., Wolfgang, C. L., Bivalacqua, T., Terezakis, S., Herman, J., Schneider, E. B. & Ahuja, N. Dec 1 2016 In : Surgery. 160, 6, p. 1628-1635 8 p.

Research output: Contribution to journalArticle

Sarcoma
Survival
Radiation
Survival Analysis
Databases

Prognostic Epigenetics

Sharma, A., Abdelfatah, E., Al Eissa, M. & Ahuja, N. Jul 1 2016 Medical Epigenetics. Elsevier Inc., p. 177-195 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Epigenomics
Genes
Genome
Biomarkers
Technology

The Future of Basic Science in Academic Surgery: Identifying Barriers to Success for Surgeon-scientists

Keswani, S. G., Moles, C. M., Morowitz, M., Zeh, H., Kuo, J. S., Levine, M. H., Cheng, L. S., Hackam, D. J., Ahuja, N., Goldstein, A. M. & Basic Science Committee of the Society of University Surgeons Sep 16 2016 (Accepted/In press) In : Annals of Surgery.

Research output: Contribution to journalArticle

National Institutes of Health (U.S.)
Surgeons
Aptitude
Research
Pressure

Time to Chemotherapy After Abdominoperineal Resection: Comparison Between Primary Closure and Perineal Flap Reconstruction

Althumairi, A. A., Canner, J. K., Ahuja, N., Sacks, J. M., Safar, B. & Efron, J. E. Jan 1 2016 In : World journal of surgery. 40, 1, p. 225-230 6 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Drug Therapy
Wound Healing
Wounds and Injuries
Adenocarcinoma

Tumors with unmethylated MLH1 and the CpG island methylator phenotype are associated with a poor prognosis in stage ii colorectal cancer patients

Fu, T., Liu, Y., Li, K., Wan, W., Pappou, E. P., Iacobuzio-Donahue, C. A., Kerner, Z., Baylin, S. B., Wolfgang, C. L. & Ahuja, N. 2016 In : Oncotarget. 7, 52, p. 86480-86489 10 p.

Research output: Contribution to journalArticle

CpG Islands
Colorectal Neoplasms
Phenotype
Neoplasms
Methylation

Understanding the Barriers to Hiring and Promoting Women in Surgical Subspecialties

Valsangkar, N., Fecher, A. M., Rozycki, G. S., Blanton, C., Bell, T. M., Freischlag, J., Ahuja, N., Zimmers, T. A. & Koniaris, L. G. Aug 1 2016 In : Journal of the American College of Surgeons. 223, 2, p. 387-398.e2

Research output: Contribution to journalArticle

Publications
Sex Characteristics
Demography
Research
Surgical Oncology
2015

A Combination of Molecular Markers and Clinical Features Improve the Classification of Pancreatic Cysts

Springer, S. , Wang, Y. , Dal Molin, M. , Masica, D. L. , Jiao, Y. , Kinde, I. , Blackford, A. , Raman, S. P. , Wolfgang, C. L. , Tomita, T. , Niknafs, N. , Douville, C. , Ptak, J. , Dobbyn, L. , Allen, P. J. , Klimstra, D. S. , Schattner, M. A. , Schmidt, C. M. , Yip-Schneider, M. , Cummings, O. W. & 47 others Brand, R. E., Zeh, H. J., Singhi, A. D., Scarpa, A., Salvia, R., Malleo, G., Zamboni, G., Falconi, M., Jang, J. Y., Kim, S. W., Kwon, W., Hong, S. M., Song, K. B., Kim, S. C., Swan, N., Murphy, J., Geoghegan, J., Brugge, W., Fernandez-Del Castillo, C., Mino-Kenudson, M., Schulick, R., Edil, B. H., Adsay, V., Paulino, J., Van Hooft, J., Yachida, S., Nara, S., Hiraoka, N., Yamao, K., Hijioka, S., Van Der Merwe, S., Goggins, M., Canto, M. I., Ahuja, N., Hirose, K., Makary, M., Weiss, M. J., Cameron, J., Pittman, M., Eshleman, J. R., Diaz, L. A., Papadopoulos, N., Kinzler, K. W., Karchin, R., Hruban, R. H., Vogelstein, B. & Lennon, A. M. Nov 1 2015 In : Gastroenterology. 149, 6, p. 1501-1510 10 p.

Research output: Contribution to journalArticle

Pancreatic Cyst
Biomarkers
Cysts
Pancreatic Neoplasms
Neoplasms

AGA Guidelines for the Management of Pancreatic Cysts

Lennon, A. M., Ahuja, N. & Wolfgang, C. L. Sep 1 2015 In : Gastroenterology. 149, 3, p. 825-826 2 p.

Research output: Contribution to journalArticle

Neoplasms, Cystic, Mucinous, and Serous
Pancreatic Ductal Carcinoma
Pancreatic Cyst
Pancreatic Pseudocyst
Asymptomatic Diseases

Early detection of pancreatic cancer

Kim, V. M. & Ahuja, N. 2015 In : Chinese Journal of Cancer Research. 27, 4, p. 321-331 11 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Early Detection of Cancer
Adenocarcinoma
Neoplasms
Saliva

Early hospital readmission for gastrointestinal-related complications predicts long-term mortality after pancreatectomy

Hicks, C. W., Tosoian, J. J., Craig-Schapiro, R., Valero, V., Cameron, J. L., Eckhauser, F. E., Hirose, K., Makary, M. A., Pawlik, T. M., Ahuja, N., Weiss, M. J. & Wolfgang, C. L. Oct 1 2015 In : American Journal of Surgery. 210, 4, p. 636-642.e1

Research output: Contribution to journalArticle

Patient Readmission
Pancreatectomy
Mortality
Multivariate Analysis
Databases

Epigenetic silencing of neurofilament genes promotes an aggressive phenotype in breast cancer

Calmon, M. F., Jeschke, J., Zhang, W., Dhir, M., Siebenkäs, C., Herrera, A., Tsai, H. C., O’Hagan, H. M., Pappou, E. P., Hooker, C. M., Fu, T., Schuebel, K. E., Gabrielson, E., Rahal, P., Herman, J. G., Baylin, S. B. & Ahuja, N. Jan 1 2015 In : Epigenetics. 10, 7, p. 622-632 11 p.

Research output: Contribution to journalArticle

Intermediate Filaments
Gene Silencing
Epigenomics
Breast Neoplasms
Phenotype

Epigenetic therapy for solid tumors: From bench science to clinical trials

Juo, Y. Y., Gong, X. J., Mishra, A., Cui, X., Baylin, S. B., Azad, N. S. & Ahuja, N. Apr 1 2015 In : Epigenomics. 7, 2, p. 215-235 21 p.

Research output: Contribution to journalArticle

Epigenomics
Clinical Trials
Neoplasms
CpG Islands
Histone Deacetylase Inhibitors

Multimodal Therapy in the Treatment of Prostate Sarcoma: The Johns Hopkins Experience

Ball, M. W., Sundi, D., Reese, A. C., Meyer, C. F., Terezakis, S. A., Efron, J. E., Schoenberg, M. P., Epstein, J. I., Ahuja, N. & Bivalacqua, T. J. Oct 1 2015 In : Clinical Genitourinary Cancer. 13, 5, p. 435-440 6 p.

Research output: Contribution to journalArticle

Sarcoma
Prostate
Survival
Recurrence
Therapeutics
Combined Modality Therapy
Precision Medicine
Gastrointestinal Neoplasms
Genetic Testing
Tumor Biomarkers

Promoter methylation of CDO1 identifies clear-cell renal cell cancer patients with poor survival outcome

Deckers, I. A. G., Schouten, L. J., Van Neste, L., Van Vlodrop, I. J. H., Soetekouw, P. M. M. B., Baldewijns, M. M. L. L., Jeschke, J., Ahuja, N., Herman, J. G., Van Den Brandt, P. A. & Van Engeland, M. Aug 1 2015 In : Clinical Cancer Research. 21, 15, p. 3492-3500 9 p.

Research output: Contribution to journalArticle

Cysteine Dioxygenase
Renal Cell Carcinoma
Methylation
Survival
Cell Survival