Nicole Anders

Research Associate

20122020

Research output per year

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Research Output

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Article
2020

A Phase I Study of Dinaciclib in Combination With MK-2206 in Patients With Advanced Pancreatic Cancer

Murphy, A. G., Zahurak, M., Shah, M., Weekes, C. D., Hansen, A., Siu, L. L., Spreafico, A., LoConte, N., Anders, N., Miles, T., Rudek-Renaut, M., Doyle, L. A., Nelkin, B. D., Maitra, A. & Azad, N. S., 2020, (Accepted/In press) In : Clinical and translational science.

Research output: Contribution to journalArticle

Open Access

Characterization of an Adapted Murine Model of Intrauterine Inflammation–Induced Preterm Birth

Zierden, H. C., Ortiz Ortiz, J. I., Dimitrion, P., Laney, V., Bensouda, S., Anders, N. M., Scardina, M., Hoang, T., Ronnett, B. M., Hanes, J., Burd, I., Mahendroo, M. & Ensign, L. M., Feb 2020, In : American Journal of Pathology. 190, 2, p. 295-305 11 p.

Research output: Contribution to journalArticle

Gelling hypotonic polymer solution for extended topical drug delivery to the eye

Kim, Y. C., Shin, M. D., Hackett, S. F., Hsueh, H. T., Formica, R., Date, A., Han, H., Kim, B. J., Xiao, A., Kim, Y., Ogunnaike, L., Anders, N., Hemingway, A., He, P., Jun, A. S., McDonnell, P. J., Eberhart, C., Pitha, I., Zack, D. J., Campochiaro, P. A. & 2 others, Hanes, J. & Ensign-Hodges, L., 2020, (Accepted/In press) In : Nature biomedical engineering.

Research output: Contribution to journalArticle

Sustained delivery of acriflavine from the suprachoroidal space provides long term suppression of choroidal neovascularization

Hackett, S. F., Fu, J., Kim, Y. C., Tsujinaka, H., Shen, J., Lima e Silva, R., Khan, M., Hafiz, Z., Wang, T., Shin, M., Anders, N. M., He, P., Ensign, L. M., Hanes, J. & Campochiaro, P. A., Jun 2020, In : Biomaterials. 243, 119935.

Research output: Contribution to journalArticle

2019

A phase 1 trial of the oral DNA methyltransferase inhibitor CC-486 and the histone deacetylase inhibitor romidepsin in advanced solid tumors

Gaillard, S. L., Zahurak, M., Sharma, A., Durham, J. N., Reiss, K. A., Sartorius-Mergenthaler, S., Downs, M., Anders, N. M., Ahuja, N., Rudek, M. A. & Azad, N., Aug 15 2019, In : Cancer. 125, 16, p. 2837-2845 9 p.

Research output: Contribution to journalArticle

Development of a mucoinert progesterone nanosuspension for safer and more effective prevention of preterm birth

Hoang, T., Zierden, H., Date, A., Ortiz, J., Gumber, S., Anders, N., He, P., Segars, J., Hanes, J., Mahendroo, M. & Ensign, L. M., Feb 10 2019, In : Journal of Controlled Release. 295, p. 74-86 13 p.

Research output: Contribution to journalArticle

Increased uptake of doxorubicin by cells undergoing heat stress does not explain its synergistic cytotoxicity with hyperthermia

Sharma, A., Özayral, S., Caserto, J. S., ten Cate, R., Anders, N. M., Barnett, J. D., Kandala, S. K., Henderson, E., Stewart, J., Liapi, E., Rudek, M. A., Franken, N. A. P., Oei, A. L., Korangath, P., Bunz, F. & Ivkov, R., Jan 1 2019, In : International Journal of Hyperthermia. 36, 1, p. 712-720 9 p.

Research output: Contribution to journalArticle

Open Access
2018

Covalent Rpn13-Binding Inhibitors for the Treatment of Ovarian Cancer

Anchoori, R., Jiang, R., Peng, S., Soong, R. S., Algethami, A., Rudek-Renaut, M., Anders, N., Hung, C-F., Chen, X., Lu, X., Kayode, O., Dyba, M., Walters, K. J. & Roden, R. S., Sep 30 2018, In : ACS Omega. 3, 9, p. 11917-11929 13 p.

Research output: Contribution to journalArticle

Muscadine grape skin extract (MPX) in men with biochemically recurrent prostate cancer: A randomized, multicenter, placebo-controlled clinical trial

Paller, C. J., Zhou, X. C., Heath, E. I., Taplin, M. E., Mayer, T., Stein, M. N., Bubley, G. J., Pili, R., Hudson, T., Kakarla, R., Abbas, M. M., Anders, N. M., Dowling, D., King, S., Bruns, A. B., Wagner, W. D., Drake, C. G., Antonarakis, E. S., Eisenberger, M. A., Denmeade, S. R. & 3 others, Rudek, M. A., Rosner, G. L. & Carducci, M. A., Jan 15 2018, In : Clinical Cancer Research. 24, 2, p. 306-315 10 p.

Research output: Contribution to journalArticle

Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer

Converse, P., Almeida, D. V., Tasneen, R., Saini, V., Tyagi, S., Ammerman, N. C., Li, S. Y., Anders, N. M., Rudek, M. A., Grosset, J. & Nuermberger, E. L., Aug 1 2018, In : PLoS Neglected Tropical Diseases. 12, 8, e0006728.

Research output: Contribution to journalArticle

Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

Kalin, J. H., Wu, M., Gomez, A. V., Song, Y., Das, J., Hayward, D., Adejola, N., Wu, M., Panova, I., Chung, H. J., Kim, E., Roberts, H. J., Roberts, J. M., Prusevich, P., Jeliazkov, J. R., Roy Burman, S. S., Fairall, L., Milano, C., Eroglu, A., Proby, C. M. & 14 others, Dinkova-Kostova, A. T., Hancock, W. W., Gray, J. J., Bradner, J. E., Valente, S., Mai, A., Anders, N. M., Rudek, M. A., Hu, Y., Ryu, B., Schwabe, J. W. R., Mattevi, A., Alani, R. M. & Cole, P. A., Dec 1 2018, In : Nature communications. 9, 1, 53.

Research output: Contribution to journalArticle

The effect of an adenosine A$$subscript$$2A$atsubscriptat$ agonist on intra-tumoral concentrations of temozolomide in patients with recurrent glioblastoma

Jackson, S., Weingart, J. D., Nduom, E. K., Harfi, T. T., George, R. T., McAreavey, D., Ye, X., Anders, N., Peer, C., Figg, W. D., Gilbert, M., Rudek-Renaut, M. & Grossman, S. A., Jan 15 2018, In : Fluids and Barriers of the CNS. 15, 1, 2.

Research output: Contribution to journalArticle

The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma

Bharathy, N., Berlow, N. E., Wang, E., Abraham, J., Settelmeyer, T. P., Hooper, J. E., Svalina, M. N., Ishikawa, Y., Zientek, K., Bajwa, Z., Goros, M. W., Hernandez, B. S., Wolff, J. E., Rudek, M. A., Xu, L., Anders, N. M., Pal, R., Harrold, A. P., Davies, A. M., Ashok, A. & 18 others, Bushby, D., Mancini, M., Noakes, C., Goodwin, N. C., Ordentlich, P., Keck, J., Hawkins, D. S., Rudzinski, E. R., Chatterjee, B., Bächinger, H. P., Barr, F. G., Liddle, J., Garcia, B. A., Mansoor, A., Perkins, T. J., Vakoc, C. R., Michalek, J. E. & Keller, C., Nov 20 2018, In : Science signaling. 11, 557, aau7632.

Research output: Contribution to journalArticle

2017

Pharmacodynamic and pharmacokinetic neoadjuvant study of hedgehog pathway inhibitor Sonidegib (LDE-225) in men with high-risk localized prostate cancer undergoing prostatectomy

Ross, A. E., Hughes, R. M., Glavaris, S., Ghabili, K., He, P., Anders, N. M., Harb, R., Tosoian, J. J., Marchionni, L., Schaeffer, E. M., Partin, A. W., Allaf, M. E., Bivalacqua, T. J., Chapman, C., O'Neal, T., DeMarzo, A. M., Hurley, P. J., Rudek, M. A. & Antonarakis, E. S., 2017, In : Oncotarget. 8, 61, p. 104182-104192 11 p.

Research output: Contribution to journalArticle

2016

A robust and rapid liquid chromatography tandem mass spectrometric method for the quantitative analysis of 5-azacytidine

Anders, N. M., Wanjiku, T. M., He, P., Azad, N. S. & Rudek, M. A., Mar 1 2016, In : Biomedical Chromatography. 30, 3, p. 494-496 3 p.

Research output: Contribution to journalArticle

Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs

Fox, J. M., Moynihan, J. R., Mott, B. T., Mazzone, J. R., Anders, N. M., Brown, P. A., Rudek, M. A., Liu, J. O., Arav-Boger, R., Posner, G. H., Civin, C. I. & Chen, X., Jan 1 2016, In : Oncotarget. 7, 6, p. 7268-7279 12 p.

Research output: Contribution to journalArticle

Metformin Protects Cells from Mutant Huntingtin Toxicity Through Activation of AMPK and Modulation of Mitochondrial Dynamics

Jin, J., Gu, H., Anders, N. M., Ren, T., Jiang, M., Tao, M., Peng, Q., Rudek, M. A. & Duan, W., Dec 1 2016, In : Neuromolecular medicine. 18, 4, p. 581-592 12 p.

Research output: Contribution to journalArticle

The effect of regadenoson-induced transient disruption of the blood–brain barrier on temozolomide delivery to normal rat brain

Jackson, S., Anders, N. M., Mangraviti, A., Wanjiku, T. M., Sankey, E. W., Liu, A., Brem, H., Tyler, B., Rudek, M. A. & Grossman, S. A., Feb 1 2016, In : Journal of neuro-oncology. 126, 3, p. 433-439 7 p.

Research output: Contribution to journalArticle

2015

A phase i study of muscadine grape skin extract in men with biochemically recurrent prostate cancer: Safety, tolerability, and dose determination

Paller, C. J., Rudek, M. A., Zhou, X. C., Wagner, W. D., Hudson, T. S., Anders, N., Hammers, H. J., Dowling, D., King, S., Antonarakis, E. S., Drake, C. G., Eisenberger, M. A., Denmeade, S. R., Rosner, G. L. & Carducci, M. A., Oct 1 2015, In : Prostate. 75, 14, p. 1518-1525 8 p.

Research output: Contribution to journalArticle

Preclinical assessment of the interactions between the antiretroviral drugs, ritonavir and efavirenz, and the tyrosine kinase inhibitor erlotinib

Deeken, J. F., Beumer, J. H., Anders, N. M., Wanjiku, T., Rusnak, M. & Rudek, M. A., Oct 22 2015, In : Cancer Chemotherapy and Pharmacology. 76, 4, p. 813-819 7 p.

Research output: Contribution to journalArticle

2012

HIV nonnucleoside reverse transcriptase inhibitors and trimethoprim- sulfamethoxazole inhibit plasmodium liver stages

Hobbs, C. V., Voza, T., De La Vega, P., Vanvliet, J., Conteh, S., Penzak, S. R., Fay, M. P., Anders, N., Ilmet, T., Li, Y., Borkowsky, W., Krzych, U., Duffy, P. E. & Sinnis, P., Dec 1 2012, In : Journal of Infectious Diseases. 206, 11, p. 1706-1714 9 p.

Research output: Contribution to journalArticle