Nicolas Arbez

Research Associate

20022019
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Fingerprint Dive into the research topics where Nicolas Arbez is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Huntington Disease Medicine & Life Sciences
Neurons Medicine & Life Sciences
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Toxicity Chemical Compounds
Amyloid Medicine & Life Sciences
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Nerve Tissue Proteins Medicine & Life Sciences

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Research Output 2002 2019

Cysteamine Protects Neurons from Mutant Huntingtin Toxicity

Arbez, N., Roby, E., Akimov, S., Eddings, C., Ren, M., Wang, X. & Ross, C. A., Jan 1 2019, In : Journal of Huntington's Disease. 8, 2, p. 129-143 15 p.

Research output: Contribution to journalArticle

Cysteamine
Neurons
Brain-Derived Neurotrophic Factor
Neuroprotective Agents
Cysteine

Pridopidine protects neurons from mutant-huntingtin toxicity via the sigma-1 receptor

Eddings, C. R., Arbez, N., Akimov, S., Geva, M., Hayden, M. R. & Ross, C. A., Sep 1 2019, In : Neurobiology of Disease. 129, p. 118-129 12 p.

Research output: Contribution to journalArticle

Neurons
Huntington Disease
Neuroprotective Agents
Endoplasmic Reticulum
trkB Receptor

N6-Furfuryladenine is protective in Huntington’s disease models by signaling huntingtin phosphorylation

Bowie, L. E., Maiuri, T., Alpaugh, M., Gabriel, M., Arbez, N., Galleguillos, D., Hung, C. L. K., Patel, S., Xia, J., Hertz, N. T., Ross, C. A., Litchfield, D. W., Sipione, S. & Truant, R., Jul 24 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 30, p. E7081-E7090

Research output: Contribution to journalArticle

Huntington Disease
Casein Kinase II
Phosphorylation
Adenine Phosphoribosyltransferase
DNA Damage

Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice

The HD iPSC Consortium, May 1 2017, In : Nature Neuroscience. 20, 5, p. 648-660 13 p.

Research output: Contribution to journalArticle

Huntington Disease
Pharmacology
Histone Code
Genes
Isoxazoles

Mutant Huntingtin Disrupts the Nuclear Pore Complex

Grima, J. C., Daigle, J. G., Arbez, N., Cunningham, K. C., Zhang, K., Ochaba, J., Geater, C., Morozko, E., Stocksdale, J., Glatzer, J. C., Pham, J. T., Ahmed, I., Peng, Q., Wadhwa, H., Pletnikova, O., Troncoso, J. C., Duan, W., Snyder, S. H., Ranum, L. P. W., Thompson, L. M. & 3 others, Lloyd, T., Ross, C. A. & Rothstein, J. D., Apr 5 2017, In : Neuron. 94, 1, p. 93-107.e6

Research output: Contribution to journalArticle

Nuclear Pore
Nuclear Pore Complex Proteins
Cell Nucleus Active Transport
Huntington Disease
Neurons