Nicolas Arbez

Research Associate

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  • 10 Similar Profiles
Huntington Disease Medicine & Life Sciences
Neurons Medicine & Life Sciences
Poisons Medicine & Life Sciences
Caspase 6 Medicine & Life Sciences
Toxicity Chemical Compounds
Amyloid Medicine & Life Sciences
Post Translational Protein Processing Medicine & Life Sciences
Nerve Tissue Proteins Medicine & Life Sciences

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Research Output 2002 2019

Cysteamine Protects Neurons from Mutant Huntingtin Toxicity

Arbez, N., Roby, E., Akimov, S., Eddings, C., Ren, M., Wang, X. & Ross, C. A., Jan 1 2019, In : Journal of Huntington's Disease. 8, 2, p. 129-143 15 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Neuroprotective Agents

Pridopidine protects neurons from mutant-huntingtin toxicity via the sigma-1 receptor

Eddings, C. R., Arbez, N., Akimov, S., Geva, M., Hayden, M. R. & Ross, C. A., Sep 1 2019, In : Neurobiology of Disease. 129, p. 118-129 12 p.

Research output: Contribution to journalArticle

Huntington Disease
Neuroprotective Agents
Endoplasmic Reticulum
trkB Receptor

N6-Furfuryladenine is protective in Huntington’s disease models by signaling huntingtin phosphorylation

Bowie, L. E., Maiuri, T., Alpaugh, M., Gabriel, M., Arbez, N., Galleguillos, D., Hung, C. L. K., Patel, S., Xia, J., Hertz, N. T., Ross, C. A., Litchfield, D. W., Sipione, S. & Truant, R., Jul 24 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 30, p. E7081-E7090

Research output: Contribution to journalArticle

Huntington Disease
Casein Kinase II
Adenine Phosphoribosyltransferase
DNA Damage

Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice

The HD iPSC Consortium, May 1 2017, In : Nature Neuroscience. 20, 5, p. 648-660 13 p.

Research output: Contribution to journalArticle

Huntington Disease
Histone Code

Mutant Huntingtin Disrupts the Nuclear Pore Complex

Grima, J. C., Daigle, J. G., Arbez, N., Cunningham, K. C., Zhang, K., Ochaba, J., Geater, C., Morozko, E., Stocksdale, J., Glatzer, J. C., Pham, J. T., Ahmed, I., Peng, Q., Wadhwa, H., Pletnikova, O., Troncoso, J. C., Duan, W., Snyder, S. H., Ranum, L. P. W., Thompson, L. M. & 3 others, Lloyd, T., Ross, C. A. & Rothstein, J. D., Apr 5 2017, In : Neuron. 94, 1, p. 93-107.e6

Research output: Contribution to journalArticle

Nuclear Pore
Nuclear Pore Complex Proteins
Cell Nucleus Active Transport
Huntington Disease