Nicholas Zachos

Associate Professor

20022019
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Fingerprint Dive into the research topics where Nicholas Zachos is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Microvilli Medicine & Life Sciences
Sodium-Hydrogen Antiporter Medicine & Life Sciences
Papio Medicine & Life Sciences
Proteins Medicine & Life Sciences
Diarrhea Medicine & Life Sciences
letrozole Medicine & Life Sciences
Intestines Medicine & Life Sciences
Brushes Chemical Compounds

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Research Output 2002 2019

Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and Braf V600E -Induced Tumorigenesis

Tao, Y., Kang, B., Petkovich, D. A., Bhandari, Y. R., In, J., Stein-O'Brien, G., Kong, X., Xie, W., Zachos, N., Maegawa, S., Vaidya, H., Brown, S., Yen, R-W., Shao, X., Thakor, J., Lu, Z., Cai, Y., Zhang, Y., Mallona, I., Peinado, M. A. & 6 others, Zahnow, C., Ahuja, N., Fertig, E., Issa, J. P., Baylin, S. B. & Easwaran, H., Feb 11 2019, In : Cancer cell. 35, 2, p. 315-328.e6

Research output: Contribution to journalArticle

Epigenomics
Organoids
Colon
Carcinogenesis
Clustered Regularly Interspaced Short Palindromic Repeats

Evaluating shigella flexneri pathogenesis in the human enteroid model

Ranganathan, S., Doucet, M., Grassel, C. L., Delaine-Elias, B. O., Zachos, N. & Barry, E. M., Apr 1 2019, In : Infection and Immunity. 87, 4, e00740.

Research output: Contribution to journalArticle

Open Access
Shigella flexneri
Shigella
Transformed Cell Line
Animal Models
Intestines

Human Intestinal Enteroids: New Models to Study Gastrointestinal Virus Infections

Zou, W. Y., Blutt, S. E., Crawford, S. E., Ettayebi, K., Zeng, X. L., Saxena, K., Ramani, S., Karandikar, U. C., Zachos, N. & Estes, M. K., Jan 1 2019, In : Methods in molecular biology (Clifton, N.J.). 1576, p. 229-247 19 p.

Research output: Contribution to journalArticle

Virus Diseases
Rotavirus
Norovirus
Viruses
Rotavirus Infections

Using Enteroendocrine Cell–Enriched Human Enteroids to Evaluate Responses to Gut Stimuli

Zachos, N., Jan 1 2019, In : CMGH. 8, 2, p. 291-292 2 p.

Research output: Contribution to journalEditorial

Open Access
Enteroendocrine Cells

Enterohemorrhagic E. Coli (EHEC)—Secreted serine protease EspP stimulates electrogenic ion transport in human colonoid monolayers

Tse, C. M., In, J. G., Yin, J., Donowitz, M., Doucet, M., Foulke-Abel, J., Ruiz-Perez, F., Nataro, J. P., Zachos, N., Kaper, J. B. & Kovbasnjuk, O. N., Sep 1 2018, In : Toxins. 10, 9, 351.

Research output: Contribution to journalArticle

Enterohemorrhagic Escherichia coli
Ion Transport
Serine Proteases
Escherichia coli
Monolayers