Nicholas Theodore

Professor

19962020
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Research Output 1996 2020

2020

Assessment of a Triage Protocol for Emergent Neurosurgical Cases at a Single Institution

Ehresman, J., Ahmed, A. K., Lubelski, D., Pennington, Z., Jiang, B., Zygourakis, C., Cottrill, E. & Theodore, N., Jan 1 2020, (Accepted/In press) In : World neurosurgery.

Research output: Contribution to journalArticle

Triage
Craniotomy
Trauma Centers
Hematoma
Neurosurgical Procedures

The effect of electrical stimulation therapies on spinal fusion: A cross-disciplinary systematic review and meta-analysis of the preclinical and clinical data

Cottrill, E., Pennington, Z., Ahmed, A. K., Lubelski, D., Goodwin, M. L., Perdomo-Pantoja, A., Westbroek, E. M., Theodore, N., Witham, T. & Sciubba, D., Jan 1 2020, In : Journal of Neurosurgery: Spine. 32, 1, p. 106-126 21 p.

Research output: Contribution to journalArticle

Open Access
Electric Stimulation Therapy
Spinal Fusion
Electric Stimulation
Meta-Analysis
Technology

The effect of renin-angiotensin system blockers on spinal cord dysfunction and imaging features of spinal cord compression in patients with symptomatic cervical spondylosis

Perdomo-Pantoja, A., Chara, A., Kalb, S., Casaos, J., Ahmed, A. K., Pennington, Z., Cottrill, E., Shah, S., Jiang, B., Manbachi, A., Zygourakis, C., Witham, T. F. & Theodore, N., Jan 1 2020, (Accepted/In press) In : Spine Journal.

Research output: Contribution to journalArticle

Spondylosis
Spinal Cord Compression
Renin-Angiotensin System
Spinal Cord
Hypertension

Time to recovery predicted by the severity of postoperative C5 palsy

Pennington, Z., Lubelski, D., Westbroek, E. M., Ahmed, A. K., Ehresman, J., Goodwin, M. L., Lo, S. F., Witham, T. F., Bydon, A., Theodore, N. & Sciubba, D. M., Jan 1 2020, In : Journal of Neurosurgery: Spine. 32, 2, p. 191-199 9 p.

Research output: Contribution to journalArticle

Paralysis
Foraminotomy
Decompression
Hypesthesia
Kaplan-Meier Estimate
2019

3D-2D image registration in virtual long-film imaging: Application to spinal deformity correction

Uneri, A., Zhang, X., Stayman, J. W., Helm, P. A., Osgood, G. M., Theodore, N. & Siewerdsen, J. H., Jan 1 2019, Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling. Fei, B. & Linte, C. A. (eds.). SPIE, 109511H. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10951).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Image registration
slots
Imaging techniques
Workflow
Bone Fractures

Accuracy of Current Techniques for Placement of Pedicle Screws in the Spine: A Comprehensive Systematic Review and Meta-Analysis of 51,161 Screws

Perdomo-Pantoja, A., Ishida, W., Zygourakis, C., Holmes, C., Iyer, R. R., Cottrill, E., Theodore, N., Witham, T. F. & Lo, S., Jan 1 2019, In : World neurosurgery.

Research output: Contribution to journalReview article

Meta-Analysis
Spine
Tomography
Fluoroscopy
Thorax

A retrospective cohort analysis of the effects of renin-angiotensin system inhibitors on spinal fusion in ACDF patients

Perdomo-Pantoja, A., Shamoun, F., Holmes, C., Ishida, W., Ramhmdani, S., Cottrill, E., Bydon, A., Lo, S., Theodore, N. & Witham, T. F., Jan 1 2019, In : Spine Journal.

Research output: Contribution to journalArticle

Cohort Effect
Diskectomy
Spinal Fusion
Renin-Angiotensin System
Cohort Studies

Augmented reality-assisted pedicle screw insertion: A cadaveric proof-of-concept study

Molina, C. A., Theodore, N., Karim Ahmed, A., Westbroek, E. M., Mirovsky, Y., Harel, R., Orru, E., Khan, M., Witham, T. & Sciubba, D. M., Jan 1 2019, In : Journal of Neurosurgery: Spine. 31, 1, p. 139-146 8 p.

Research output: Contribution to journalArticle

Robotics
Torso
Retina
Pedicle Screws
Technology

Automatic analysis of global spinal alignment from spine CT images

Doerr, S. A., De Silva, T., Vijayan, R., Han, R., Uneri, A., Ketcha, M. D., Zhang, X., Khanna, N., Westbroek, E., Jiang, B., Zygourakis, C., Aygun, N., Theodore, N. & Siewerdsen, J. H., Jan 1 2019, Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling. Fei, B. & Linte, C. A. (eds.). SPIE, 1095104. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10951).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

spine
quartiles
Spine
alignment
Lordosis

Automatic pedicle screw planning using atlas-based registration of anatomy and reference trajectories

Vijayan, R., De Silva, T., Han, R., Zhang, X., Uneri, A., Doerr, S., Ketcha, M., Perdomo-Pantoja, A., Theodore, N. & Siewerdsen, J. H., Aug 21 2019, In : Physics in medicine and biology. 64, 16, 165020.

Research output: Contribution to journalArticle

Atlases
Anatomy
Spine
Cone-Beam Computed Tomography
Workflow

Automatic trajectory and instrument planning for robot-assisted spine surgery

Vijayan, R. C., De Silva, T. S., Han, R., Uneri, A., Doerr, S. A., Ketcha, M. D., Perdomo-Pantoja, A., Theodore, N. & Siewerdsen, J. H., Jan 1 2019, Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling. Fei, B. & Linte, C. A. (eds.). SPIE, 1095102. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10951).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

trajectory planning
spine
robots
surgery
Surgery

Automatic vertebrae localization in spine CT: A deep-learning approach for image guidance and surgical data science

Levine, M., De Silva, T., Ketcha, M. D., Vijayan, R., Doerr, S., Uneri, A., Vedula, S., Theodore, N. & Siewerdsen, J. H., Jan 1 2019, Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling. Fei, B. & Linte, C. A. (eds.). SPIE, 109510S. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10951).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

vertebrae
spine
Surgery
learning
Spine

Biomechanical Effects of an Oblique Lumbar PEEK Cage and Posterior Augmentation

Soriano-Baron, H., Newcomb, A. G. U. S., Malhotra, D., Martinez del Campo, E., Palma, A. E., Theodore, N., Crawford, N. R., Kelly, B. P. & Kaibara, T., Jan 1 2019, In : World neurosurgery.

Research output: Contribution to journalArticle

Articular Range of Motion
Equipment and Supplies
Spinal Fusion
Biomechanical Phenomena
Pedicle Screws

Biomechanical Evaluation of Cervicothoracic Junction Fusion Constructs

Godzik, J., Dalton, J. F., Martinez-del-Campo, E., Newcomb, A. G. U. S., Dominguez, F., Reyes, P. M., Theodore, N., Kelly, B. P. & Crawford, N. R., Jan 1 2019, (Accepted/In press) In : World Neurosurgery.

Research output: Contribution to journalArticle

Articular Range of Motion
Spine
In Vitro Techniques
Pedicle Screws
Open Access
Minimally Invasive Surgical Procedures
Spine
Perfusion

Daniel Ruge: The first neurosurgeon to serve as physician to the president

Ahmed, A. K., Martinez-Del-Campo, E. & Theodore, N., Jan 1 2019, In : Journal of neurosurgery. 131, 1, p. 311-317 7 p.

Research output: Contribution to journalReview article

Physicians
History of Medicine
United States Department of Veterans Affairs
Emergency Medicine
Neurosurgery

Diagnostic and therapeutic values of intraoperative electrophysiological neuromonitoring during resection of intradural extramedullary spinal tumors: A single-center retrospective cohort and meta-analysis

Ishida, W., Casaos, J., Chandra, A., D’Sa, A., Ramhmdani, S., Perdomo-Pantoja, A., Theodore, N., Jallo, G., Gokaslan, Z. L., Wolinsky, J. P., Sciubba, D., Bydon, A., Witham, T. F. & Lo, S., Jun 1 2019, In : Journal of Neurosurgery: Spine. 30, 6, p. 839-849 11 p.

Research output: Contribution to journalArticle

Meta-Analysis
Cohort Studies
Neoplasms
Area Under Curve
Therapeutics

Ensuring navigation integrity using robotics in spine surgery

Crawford, N., Johnson, N. & Theodore, N., Jan 1 2019, In : Journal of Robotic Surgery.

Research output: Contribution to journalArticle

Robotics
Spine
Bone and Bones
Research

First spine surgery utilizing real-time image-guided robotic assistance

Ahmed, A. K., Zygourakis, C. C., Kalb, S., Zhu, A. M., Molina, C. A., Jiang, B., Blitz, A. M., Bydon, A., Crawford, N. R. & Theodore, N., Jan 1 2019, In : Computer Assisted Surgery.

Research output: Contribution to journalArticle

Open Access
Robotics
Surgery
Spine
Neuronavigation
Robots

Genetic Predisposition to Symptomatic Lumbar Disk Herniation in Pediatric and Young Adult Patients

Theodore, N., Ahmed, A. K., Fulton, T., Mousses, S., Yoo, C., Goodwin, C. R., Danielson, J., Sciubba, D., Giers, M. B. & Kalani, M. Y. S., Jun 1 2019, In : Spine. 44, 11, p. E640-E649

Research output: Contribution to journalArticle

Genetic Predisposition to Disease
Young Adult
Aggrecans
Pediatrics
Single Nucleotide Polymorphism

Healing of type II odontoid fracture without surgery in an octogenarian — Case report and literature review

Azad, T. D., Jiang, B., Zhu, A. M. & Theodore, N., Jan 1 2019, In : Journal of Clinical Neuroscience.

Research output: Contribution to journalArticle

Neck Pain
Immobilization
Spine
Tomography
Orthotic Devices

Horner Syndrome After Anterior Cervical Discectomy and Fusion: Case Series and Systematic Review

Lubelski, D., Pennington, Z., Sciubba, D. M., Theodore, N. & Bydon, A., Jan 1 2019, (Accepted/In press) In : World neurosurgery.

Research output: Contribution to journalArticle

Horner Syndrome
Diskectomy
Incidence
Tertiary Healthcare
Multicenter Studies

Improved intraoperative imaging in spine surgery: Clinical translation of known-component 3D image reconstruction on the O-arm system

Zhang, X., Uneri, A., Stayman, J. W., Zygourakis, C. C., Lo, S. F., Theodore, N. & Siewerdsen, J. H., Jan 1 2019, Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling. Fei, B. & Linte, C. A. (eds.). SPIE, 1095103. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10951).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

spine
Computer-Assisted Image Processing
image reconstruction
Image reconstruction
surgery

Investigational growth factors utilized in animal models of spinal fusion: Systematic review

Cottrill, E., Ahmed, A. K., Lessing, N., Pennington, Z., Ishida, W., Perdomo-Pantoja, A., Lo, S., Howell, E., Holmes, C., Rory Goodwin, C., Theodore, N., Sciubba, D. & Witham, T. F., Apr 1 2019, In : World Journal of Orthopaedics. 10, 4, p. 176-191 16 p.

Research output: Contribution to journalReview article

Open Access
Spinal Fusion
Intercellular Signaling Peptides and Proteins
Animal Models
Growth Differentiation Factor 5
Angiopoietin-1
Computer-Assisted Image Processing
Spine
Artifacts
Cone-Beam Computed Tomography
Metals

Known-component metal artifact reduction (KC-MAR) for cone-beam CT

Uneri, A., Zhang, X., Yi, T., Stayman, J. W., Helm, P. A., Osgood, G. M., Theodore, N. & Siewerdsen, J. H., Aug 21 2019, In : Physics in medicine and biology. 64, 16, 165021.

Research output: Contribution to journalArticle

Artifacts
Metals
Cadaver
Cone-Beam Computed Tomography
Computer-Assisted Image Processing

Minimally Invasive Single-Position Lateral Interbody Fusion With Robotic Bilateral Percutaneous Pedicle Screw Fixation: 2-Dimensional Operative Video

Walker, C. T., Godzik, J., Xu, D. S., Theodore, N., Uribe, J. S. & Chang, S. W., Apr 1 2019, In : Operative neurosurgery (Hagerstown, Md.). 16, 4, p. E121

Research output: Contribution to journalArticle

Open Access
Robotics
Intervertebral Disc Degeneration
Intractable Pain
Radiculopathy
Cone-Beam Computed Tomography

Minimally Invasive Transforaminal Interbody Fusion With Robotically Assisted Bilateral Pedicle Screw Fixation: 2-Dimensional Operative Video

Godzik, J., Walker, C. T., Theodore, N., Uribe, J. S., Chang, S. W. & Snyder, L. A., Mar 1 2019, In : Operative neurosurgery (Hagerstown, Md.). 16, 3, p. E86-E87

Research output: Contribution to journalArticle

Minimally Invasive Surgical Procedures
Robotics
Tomography
Spondylolisthesis
Operating Tables

New spinal robotic technologies

Jiang, B., Azad, T. D., Cottrill, E., Zygourakis, C. C., Zhu, A. M., Crawford, N. & Theodore, N., Jan 1 2019, (Accepted/In press) In : Frontiers of Medicine.

Research output: Contribution to journalComment/debate

Robotics
Technology
Spine
United States Food and Drug Administration
Randomized Controlled Trials

Operative Management of Idiopathic Spinal Cord Herniation: Case Series and Novel Technique for Repair of Recurrent Herniation

Hlubek, R. J., Xu, D. S., Mulholland, C. B., Gilson, J., Theodore, N., Turner, J. D. & Kakarla, U. K., Apr 1 2019, In : Operative neurosurgery (Hagerstown, Md.). 16, 4, p. 415-423 9 p.

Research output: Contribution to journalArticle

Spinal Cord
Spinal Cord Diseases
Collagen
Spinal Cord Regeneration
Postoperative Period

Pedicled, vascularized occipital bone graft to supplement atlantoaxial arthrodesis for the treatment of pseudoarthrosis

Reece, E. M., Vedantam, A., Lee, S., Bhadkamkar, M., Kaufman, M., Bohl, M. A., Chang, S. W., Porter, R. W., Theodore, N., Kakarla, U. K. & Ropper, A. E., Jan 1 2019, In : Journal of Clinical Neuroscience.

Research output: Contribution to journalArticle

Occipital Bone
Pseudarthrosis
Arthrodesis
Transplants
Paraspinal Muscles

Preoperative Clinical and Radiographic Variables Predict Postoperative C5 Palsy

Pennington, Z., Lubelski, D., D'Sa, A., Westbroek, E., Ahmed, A. K., Goodwin, M., Witham, T. F., Bydon, A., Theodore, N. & Sciubba, D., Jan 1 2019, In : World neurosurgery.

Research output: Contribution to journalArticle

Paralysis
Paresthesia
Decompression
Gait
Hand

Safety profile of lumbosacropelvic fixation in patients aged 60 years or older: Comparison between s2-alar-iliac screws and conventional iliac screws

Ishida, W., Ramhmdani, S., Casaos, J., Perdomo-Pantoja, A., Elder, B. D., Theodore, N., Gokaslan, Z. L., Wolinsky, J. P., Sciubba, D., Bydon, A., Witham, T. F. & Lo, S., Jan 1 2019, In : Clinical Spine Surgery.

Research output: Contribution to journalArticle

Safety
Reoperation
Surgical Wound Infection
Pseudarthrosis
Blood Volume

Spinal cord float back is not an independent predictor of postoperative C5 palsy in patients undergoing posterior cervical decompression

Pennington, Z., Lubelski, D., Westbroek, E. M., Cottrill, E., Ehresman, J., Goodwin, M. L., Lo, S. F., Witham, T. F., Theodore, N., Bydon, A. & Sciubba, D. M., Jan 1 2019, (Accepted/In press) In : Spine Journal.

Research output: Contribution to journalArticle

Decompression
Paralysis
Spinal Cord
Foraminotomy
Spine

Surgineering: curriculum concept for experiential learning in upper-level biomedical engineering

Siewerdsen, J. H., Adrales, G. L., Anderson, W. S., Carey, J. P., Creighton, F. X., DiBrito, S. R., Galaiya, D., Marohn, M. R., McNutt, T. R., Osgood, G. M., Theodore, N., Weiss, C. R. & Viswanathan, A. N., Jan 1 2019, (Accepted/In press) In : International Journal of Computer Assisted Radiology and Surgery.

Research output: Contribution to journalArticle

Biomedical Engineering
Problem-Based Learning
Biomedical engineering
Curriculum
Curricula

Unusual Cause of Trigeminal Neuralgia: First Report of Intracranial Migration of Spinal Cord Stimulator

Young, R., Jiang, B. & Theodore, N., Aug 1 2019, In : World neurosurgery. 128, p. 47-49 3 p.

Research output: Contribution to journalArticle

Trigeminal Neuralgia
Spinal Cord
Chronic Pain
Spinal Cord Stimulation
Epidural Space
2018

Advanced image registration and reconstruction using the O-Arm system: Dose reduction, image quality, and guidance using known-component models

Uneri, A., Zhang, X., Stayman, J. W., Helm, P., Osgood, G. M., Theodore, N. & Siewerdsen, J. H., Jan 1 2018, Medical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling. SPIE, Vol. 10576. 105761G

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Computer-Assisted Image Processing
Image registration
Image reconstruction
Cadaver
Image quality

Anatomic Basis for Minimally Invasive Resection of Intradural Extramedullary Lesions in Thoracic Spine

Tumialán, L. M., Theodore, N., Narayanan, M., Marciano, F. F. & Nakaji, P., Jan 1 2018, In : World Neurosurgery. 109, p. e770-e777

Research output: Contribution to journalArticle

Spine
Thorax
Spinal Canal
Spinal Cord
Neoplasms
Chronic Pain
Opioid Analgesics
Pain Management
Prescriptions
Integrative Medicine

Biomechanical Analysis of an Expandable Lumbar Interbody Spacer

Soriano-Baron, H., Newcomb, A. G. U. S., Malhotra, D., Palma, A. E., Martinez-del-Campo, E., Crawford, N. R., Theodore, N., Kelly, B. P. & Kaibara, T., Jan 1 2018, (Accepted/In press) In : World Neurosurgery.

Research output: Contribution to journalArticle

Articular Range of Motion
Pedicle Screws
Weight-Bearing

Circumferential dural resection technique and reconstruction for the removal of giant calcified transdural herniated thoracic discs

Walker, C. T., Kalani, M. Y. S., Oppenlander, M. E., Godzik, J., Martirosyan, N. L., Standerfer, R. J. & Theodore, N., Feb 1 2018, In : Journal of Neurosurgery: Spine. 28, 2, p. 167-172 6 p.

Research output: Contribution to journalArticle

Intervertebral Disc Displacement
Thorax
Spinal Cord
Decompression
Dura Mater

Computed tomography angiography as a confirmatory test for the diagnosis of brain death

Garrett, M. P., Williamson, R. W., Bohl, M. A., Bird, C. R. & Theodore, N., Feb 1 2018, In : Journal of Neurosurgery. 128, 2, p. 639-644 6 p.

Research output: Contribution to journalArticle

Brain Death
Cerebral Angiography
Neurology
Gold
Computed Tomography Angiography

Facet Joint Fixation and Anterior, Direct Lateral, and Transforaminal Lumbar Interbody Fusions for Treatment of Degenerative Lumbar Disc Diseases: Retrospective Cohort Study of a New Minimally Invasive Technique

Belykh, E., Kalinin, A. A., Martirosyan, N. L., Kerimbayev, T., Theodore, N., Preul, M. C. & Byvaltsev, V. A., Jan 1 2018, (Accepted/In press) In : World Neurosurgery.

Research output: Contribution to journalArticle

Zygapophyseal Joint
Cohort Studies
Retrospective Studies
Therapeutics
Spinal Diseases

Image quality and dose characteristics for an O-arm intraoperative imaging system with model-based image reconstruction

Uneri, A., Zhang, X., Yi, T., Stayman, J. W., Helm, P. A., Theodore, N. & Siewerdsen, J. H., Jan 1 2018, (Accepted/In press) In : Medical Physics.

Research output: Contribution to journalArticle

Computer-Assisted Image Processing
Calibration
Arm
Head
Radiation

Immediate improvement of intraoperative monitoring signals following CSF release for cervical spine stenosis: Case report

Pennington, Z., Zygourakis, C., Ahmed, A. K., Kalb, S., Zhu, A. & Theodore, N., Jan 1 2018, (Accepted/In press) In : Journal of Clinical Neuroscience.

Research output: Contribution to journalArticle

Intraoperative Monitoring
Cerebrospinal Fluid
Pathologic Constriction
Spine
Spinal Cord Diseases

Internal decompression of the acutely contused spinal cord: Differential effects of irrigation only versus biodegradable scaffold implantation

Guest, J. D., Moore, S. W., Aimetti, A. A., Kutikov, A. B., Santamaria, A. J., Hofstetter, C. P., Ropper, A. E., Theodore, N., Ulich, T. R. & Layer, R. T., Dec 1 2018, In : Biomaterials. 185, p. 284-300 17 p.

Research output: Contribution to journalArticle

Contusions
Decompression
Irrigation
Scaffolds
Spinal Cord

Introduction: the rise of the robots in spinal surgery

Theodore, N., Arnold, P. M. & Mehta, A. I., Jul 1 2018, In : Neurosurgical Focus. 45, Video

Research output: Contribution to journalArticle

Robotics
Thoracoscopes
Nuclear Energy
Technology
Hazardous Substances

Misplacement of Stent Into Epidural Venous Plexus With Resultant Cauda Equina Syndrome and Open Surgical Treatment: A Case Report

Whiting, B. B., Mulholland, C. B., Daniels, L., Kakarla, U. K., Theodore, N. & Snyder, L. A., Sep 1 2018, In : Operative neurosurgery (Hagerstown, Md.). 15, 3, p. E23-E26

Research output: Contribution to journalArticle

Polyradiculopathy
Stents
Spinal Canal
Pathologic Constriction
Therapeutics

National Football League Head, Neck and Spine Committee's Concussion Diagnosis and Management Protocol: 2017-18 season

Ellenbogen, R. G., Batjer, H., Cardenas, J., Berger, M., Bailes, J., Pieroth, E., Heyer, R., Theodore, N., Hsu, W., Nabel, E., Maroon, J., Cantu, R., Barnes, R., Collins, J., Putukian, M., Lonser, R., Solomon, G. & Sills, A., Mar 16 2018, (Accepted/In press) In : British Journal of Sports Medicine.

Research output: Contribution to journalArticle

Football
Spine
Neck
Sports
Head

Occipital-cervical approach and stabilization

Karim Ahmed, A., Suk, I., Bydon, A. & Theodore, N., Dec 12 2018, Spinal Tumor Surgery: A Case-Based Approach. Springer International Publishing, p. 121-128 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter