Research Output 1992 2016

2016

Endocannabinoid signaling enhances visual responses through modulation of intracellular chloride levels in retinal ganglion cells

Miraucourt, L. S., Tsui, J., Gobert, D., Desjardins, J. F., Schohl, A., Sild, M., Spratt, P., Castonguay, A., De Koninck, Y., Marsh-Armstrong, N., Wiseman, P. W. & Ruthazer, E. S. Aug 8 2016 In : eLife. 5, AUGUST, e15932

Research output: Contribution to journalArticle

Endocannabinoids
Retinal Ganglion Cells
Chlorides
Inhibition (Psychology)
Cape Verde

Neuroinflammation in glaucoma: A new opportunity

Williams, P. A., Marsh-Armstrong, N. & Howell, G. R. Jul 8 2016 In : Experimental Eye Research.

Research output: Contribution to journalArticle

Glaucoma
Optic Disk
Microglia
Astrocytes
Retina

Repetitive mild traumatic brain injury with impact acceleration in the mouse: Multifocal axonopathy, neuroinflammation, and neurodegeneration in the visual system

Xu, L., Nguyen, J. V., Lehar, M., Menon, A., Rha, E., Arena, J., Ryu, J., Marsh-Armstrong, N., Marmarou, C. R. & Koliatsos, V. E. Jan 1 2016 In : Experimental Neurology. 275, p. 436-449 14 p.

Research output: Contribution to journalArticle

Brain Injuries
Wounds and Injuries
Cerebellum
Optic Nerve
Chronic Disease

Translational profiling of retinal ganglion cell optic nerve regeneration in Xenopus laevis

Whitworth, G. B., Misaghi, B. C., Rosenthal, D. M., Mills, E. A., Heinen, D. J., Watson, A. H., Ives, C. W., Ali, S. H., Bezold, K., Marsh-Armstrong, N. & Watson, F. L. Feb 12 2016 In : Developmental Biology.

Research output: Contribution to journalArticle

Nerve Regeneration
Retinal Ganglion Cells
Xenopus laevis
Optic Nerve
Ribosomes
2015

Astrocytes phagocytose focal dystrophies from shortening myelin segments in the optic nerve of Xenopus laevis at metamorphosis

Mills, E. A., Davis, C. H. O., Bushong, E. A., Boassa, D., Kim, K. Y., Ellisman, M. H. & Marsh-Armstrong, N. Aug 18 2015 In : Proceedings of the National Academy of Sciences of the United States of America. 112, 33, p. 10509-10514 6 p.

Research output: Contribution to journalArticle

Xenopus laevis
Optic Nerve
Myelin Sheath
Phagocytosis
Astrocytes

Differentiation of human ESCs to retinal ganglion cells using a CRISPR engineered reporter cell line

Sluch, V. M., Davis, C. H. O., Ranganathan, V., Kerr, J. M., Krick, K., Martin, R., Berlinicke, C. A., Marsh-Armstrong, N., Diamond, J. S., Mao, H. Q. & Zack, D. J. Nov 13 2015 In : Scientific Reports. 5, 16595

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Retinal Ganglion Cells
Cell Line
Pluripotent Stem Cells
Nanofibers

Evidence for accelerated tauopathy in the retina of transgenic P301S tau mice exposed to repetitive mild traumatic brain injury

Xu, L., Ryu, J., Nguyen, J. V., Arena, J., Rha, E., Vranis, P., Hitt, D., Marsh-Armstrong, N. & Koliatsos, V. E. Nov 1 2015 In : Experimental Neurology. 273, p. 168-176 9 p.

Research output: Contribution to journalArticle

Tauopathies
Brain Injuries
Retina
Chronic Brain Injury
Neocortex
2014

Discovery and implications of transcellular mitophagy

Davis, C. H. O. & Marsh-Armstrong, N. Dec 1 2014 In : Autophagy. 10, 12, p. 2383-2384 2 p.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Mitochondria
Quality Control
Retinal Ganglion Cells
Optic Disk

Transcellular degradation of axonal mitochondria

Davis, C. H. O., Kim, K. Y., Bushong, E. A., Mills, E. A., Boassa, D., Shih, T., Kinebuchi, M., Phan, S., Zhou, Y., Bihlmeyer, N. A., Nguyen, J. V., Jin, Y., Ellisman, M. H. & Marsh-Armstrong, N. Jul 1 2014 In : Proceedings of the National Academy of Sciences of the United States of America. 111, 26, p. 9633-9638 6 p.

Research output: Contribution to journalArticle

Mitochondria
Retinal Ganglion Cells
Optic Disk
Astrocytes
Axons
2013

Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death

Welsbie, D. S. , Yang, Z. , Ge, Y. , Mitchell, K. L. , Zhou, X. , Martin, S. E. , Berlinicke, C. A. , Hackler, L. , Fuller, J. , Fu, J. , Cao, L. H. , Han, B. , Auld, D. , Xue, T. , Hirai, S. I. , Germain, L. , Simard-Bisson, C. , Blouin, R. , Nguyen, J. V. , Davis, C. H. O. & 12 others Enke, R. A., Boye, S. L., Merbs, S. L., Marsh-Armstrong, N., Hauswirth, W. W., Diantonio, A., Nickells, R. W., Inglese, J., Hanes, J., Yau, K. W., Quigley, H. A. & Zack, D. J. Mar 5 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 10, p. 4045-4050 6 p.

Research output: Contribution to journalArticle

Leucine Zippers
Retinal Ganglion Cells
Cell Death
Phosphotransferases
Glaucoma

Synucleins Antagonize Endoplasmic Reticulum Function to Modulate Dopamine Transporter Trafficking

Oaks, A. W., Marsh-Armstrong, N., Jones, J. M., Credle, J. J. & Sidhu, A. Aug 13 2013 In : PLoS One. 8, 8, e70872

Research output: Contribution to journalArticle

Synucleins
Dopamine Plasma Membrane Transport Proteins
Endoplasmic Reticulum
dopamine
transporters
2012

Cell type-specific translational profiling in the Xenopus laevis retina

Watson, F. L., Mills, E. A., Wang, X., Guo, C., Chen, D. F. & Marsh-Armstrong, N. Dec 2012 In : Developmental Dynamics. 241, 12, p. 1960-1972 13 p.

Research output: Contribution to journalArticle

Xenopus laevis
Retina
Ribosomes
Messenger RNA
Retinal Rod Photoreceptor Cells

Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis

Peters, O. M., Millership, S., Shelkovnikova, T. A., Soto, I., Keeling, L., Hann, A., Marsh-Armstrong, N., Buchman, V. L. & Ninkina, N. Oct 2012 In : Neurobiology of Disease. 48, 1, p. 124-131 8 p.

Research output: Contribution to journalArticle

gamma-Synuclein
Amyotrophic Lateral Sclerosis
Motor Neurons
Transgenic Mice
Pathology
2011

Myelination transition zone astrocytes are constitutively phagocytic and have synuclein dependent reactivity in glaucoma

Nguyen, J. V., Soto, I., Kim, K. Y., Bushong, E. A., Oglesby, E., Valiente-Soriano, F. J., Yang, Z., Davis, C. H. O., Bedont, J. L., Son, J. L., Wei, J. O., Buchman, V. L., Zack, D. J., Vidal-Sanz, M., Ellisman, M. H. & Marsh-Armstrong, N. Jan 18 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 3, p. 1176-1181 6 p.

Research output: Contribution to journalArticle

Synucleins
Astrocytes
Glaucoma
gamma-Synuclein
Optic Disk
Ocular Hypertension
Retinal Ganglion Cells
Optic Nerve
Axons
Intermediate Filaments
2010

Glaucomatous optic nerve injury involves early astrocyte reactivity and late oligodendrocyte loss

Son, J. L., Soto, I., Oglesby, E., Lopez-Roca, T., Pease, M. E., Quigley, H. A. & Marsh-Armstrong, N. May 2010 In : GLIA. 58, 7, p. 780-789 10 p.

Research output: Contribution to journalArticle

Optic Nerve Injuries
Oligodendroglia
Astrocytes
Glaucoma
Axons

Neurodevelopmental effects of chronic exposure to elevated levels of pro-inflammatory cytokines in a developing visual system

Lee, R. H., Mills, E. A., Schwartz, N., Bell, M. R., Deeg, K. E., Ruthazer, E. S., Marsh-Armstrong, N. & Aizenman, C. D. Jan 12 2010 In : Neural Development. 5, 1, 2

Research output: Contribution to journalArticle

Cytokines
Tumor Necrosis Factor-alpha
Synapses
Larva
Pentylenetetrazole
2009

Temporal regulation of Ath5 gene expression during eye development

Willardsen, M. I., Suli, A., Pan, Y., Marsh-Armstrong, N., Chien, C. B., El-Hodiri, H., Brown, N. L., Moore, K. B. & Vetter, M. L. Feb 15 2009 In : Developmental Biology. 326, 2, p. 471-481 11 p.

Research output: Contribution to journalArticle

Gene Expression Regulation
Retina
Basic Helix-Loop-Helix Transcription Factors
Neurogenesis
Drosophila
2008

Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma

Buckingham, B. P., Inman, D. M., Lambert, W., Oglesby, E., Calkins, D. J., Steele, M. R., Vetter, M. L., Marsh-Armstrong, N. & Horner, P. J. Mar 12 2008 In : Journal of Neuroscience. 28, 11, p. 2735-2744 10 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Ganglia
Glaucoma
Axons
Nuclear Proteins

Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucoma

Bosco, A., Inman, D. M., Steele, M. R., Wu, G., Soto, I., Marsh-Armstrong, N., Hubbard, W. C., Calkins, D. J., Horner, P. J. & Vetter, M. L. Apr 2008 In : Investigative Ophthalmology and Visual Science. 49, 4, p. 1437-1446 10 p.

Research output: Contribution to journalArticle

Inbred DBA Mouse
Minocycline
Microglia
Optic Nerve
Glaucoma

Retinal ganglion cells downregulate gene expression and lose their axons within the optic nerve head in a mouse glaucoma model

Soto, I., Oglesby, E., Buckingham, B. P., Son, J. L., Roberson, E. D. O., Steele, M. R., Inman, D. M., Vetter, M. L., Horner, P. J. & Marsh-Armstrong, N. Jan 9 2008 In : Journal of Neuroscience. 28, 2, p. 548-561 14 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Optic Disk
Glaucoma
Axons
Down-Regulation
Retinal Rod Photoreceptor Cells
Rhodopsin
Xenopus laevis
Transgenes
Retina
2006

Use of a ROSA26: GFP transgenic line for long-term Xenopus fate-mapping studies

Gross, J. B., Hanken, J., Oglesby, E. & Marsh-Armstrong, N. Sep 2006 In : Journal of Anatomy. 209, 3, p. 401-413 13 p.

Research output: Contribution to journalArticle

Xenopus
Anura
genetically modified organisms
frog
Xenopus laevis
2005

Thyroid hormone controls multiple independent programs required for limb development in Xenopus laevis metamorphosis

Brown, D. D., Cai, L., Das, B., Marsh-Armstrong, N., Schreiber, A. M. & Juste, R. Aug 30 2005 In : Proceedings of the National Academy of Sciences of the United States of America. 102, 35, p. 12455-12458 4 p.

Research output: Contribution to journalArticle

Xenopus laevis
Thyroid Hormones
Extremities
Thyroid Hormone Receptors
Gene Transfer Techniques
2004
Vitamin A
Oxidoreductases
Membrane Proteins
Membranes
Proteins
Xenopus laevis
Thyroid Hormones
Spinal Cord
Extremities
Hindlimb
2003

Role of visual pigment properties in rod and cone phototransduction

Kefalov, V., Fu, Y., Marsh-Amstrong, N. & Yau, K. W. Oct 2 2003 In : Nature. 425, 6957, p. 526-531 6 p.

Research output: Contribution to journalArticle

Light Signal Transduction
Vertebrate Photoreceptor Cells
Retinal Pigments
Xenopus
Urodela
2001

Diverse developmental programs of Xenopus laevis metamorphosis are inhibited by a dominant negative thyroid hormone receptor

Schreiber, A. M., Das, B., Huang, H., Marsh-Armstrong, N. & Brown, D. D. Sep 11 2001 In : Proceedings of the National Academy of Sciences of the United States of America. 98, 19, p. 10739-10744 6 p.

Research output: Contribution to journalArticle

Thyroid Hormone Receptors
Xenopus laevis
Thyroid Hormones
Larva
Thyroid Hormone Receptors alpha
1999

Asymmetric growth and development of the Xenopus laevis retina during metamorphosis is controlled by type III deiodinase

Marsh-Armstrong, N., Huang, H., Remo, B. F., Liu, T. T. & Brown, D. D. Dec 1999 In : Neuron. 24, 4, p. 871-878 8 p.

Research output: Contribution to journalArticle

Iodide Peroxidase
Xenopus laevis
Retina
Thyroid Hormones
Thyroid Hormone Receptors

Germ-line transmission of transgenes in Xenopus laevis

Marsh-Armstrong, N., Huang, H., Berry, D. L. & Brown, D. D. Dec 7 1999 In : Proceedings of the National Academy of Sciences of the United States of America. 96, 25, p. 14389-14393 5 p.

Research output: Contribution to journalArticle

Xenopus laevis
Transgenes
Germ Cells
Anura
Green Fluorescent Proteins
Iodide Peroxidase
Xenopus laevis
Thyroid Hormones
Larva
Genes
1996

Retinoic acid establishes ventral retinal characteristics

Hyatt, G. A., Schmitt, E. A., Marsh-Armstrong, N., McCaffery, P., Dräger, U. C. & Dowling, J. E. Jan 1996 In : Development. 122, 1, p. 195-204 10 p.

Research output: Contribution to journalArticle

Tretinoin
Retina
Paired Box Transcription Factors
Aldehyde Dehydrogenase
Retinoic Acid Receptors
1995

Retinoic acid in the anteroposterior patterning of the zebrafish trunk

Marsh-Armstrong, N., McCaffery, P., Hyatt, G., Alonso, L., Dowling, J. E., Gilbert, W. & Dräger, U. C. Nov 1995 In : Roux's Archives of Developmental Biology. 205, 3-4, p. 103-113 11 p.

Research output: Contribution to journalArticle

Zebrafish
Tretinoin
retinoic acid
acid
Danio rerio
1994

Retinoic acid is necessary for development of the ventral retina in zebrafish

Marsh-Armstrong, N., Mccaffery, P., Gilbert, W., Dowling, J. E. & Dräger, U. C. Jul 19 1994 In : Proceedings of the National Academy of Sciences of the United States of America. 91, 15, p. 7286-7290 5 p.

Research output: Contribution to journalArticle

Zebrafish
Tretinoin
Retina
Enzymes
Vertebrates
1992

Retinoic acid-induced duplication of the zebrafish retina

Hyatt, G. A., Schmitt, E. A., Marsh-Armstrong, N. R. & Dowling, J. E. 1992 In : Proceedings of the National Academy of Sciences of the United States of America. 89, 17, p. 8293-8297 5 p.

Research output: Contribution to journalArticle

Zebrafish
Tretinoin
Retina
Ganglia
Axons