Research Output 1992 2018

2018

A multi-institutional registry of pediatric hospital-acquired thrombosis cases: The Children's Hospital-Acquired Thrombosis (CHAT) project

Jaffray, J., Mahajerin, A., Young, G., Goldenberg, N., Ji, L., Sposto, R., Stillings, A., Krava, E. & Branchford, B. Jan 1 2018 In : Thrombosis Research. 161, p. 67-72 6 p.

Research output: Research - peer-reviewArticle

Pediatric Hospitals
Venous Thromboembolism
Registries
Thrombosis
Pediatrics
Venous Thromboembolism
Anticoagulants
Randomized Controlled Trials
Pediatrics
Therapeutics
2017

How We Manage Pediatric Deep Venous Thrombosis

Betensky, M., Bittles, M. A., Colombani, P. & Goldenberg, N. A. Mar 1 2017 In : Seminars in Interventional Radiology. 34, 1, p. 35-49 15 p., 00990

Research output: Research - peer-reviewArticle

Venous Thromboembolism
Venous Thrombosis
Pediatrics
Anticoagulants
Mechanical Thrombolysis

Improved sensitivity and specificity of pediatric hospital-acquired venous thromboembolism case identification by addition of radiographic and pharmacologic elements

Dittmar, M., Smith, N., Warren, B., Clark, B., Wathen, B., Hammett, K., Reiter, P., Hilden, J., Goldenberg, N. & Branchford, B. Jun 1 2017 In : Thrombosis Research. 154, p. 93-95 3 p.

Research output: Research - peer-reviewLetter

Pediatric Hospitals
Venous Thromboembolism
Sensitivity and Specificity

Post-thrombotic syndrome in children

Betensky, M. & Goldenberg, N. A. 2017 (Accepted/In press) In : Thrombosis Research.

Research output: Research - peer-reviewArticle

Pediatrics
Venous Thrombosis
Research
Therapeutics
Risk Management
research implementation
children's hospital
educational program
nursing
nurse

Pulmonary embolism and in situ pulmonary artery thrombosis in paediatrics: A systematic review

Rajpurkar, M., Biss, T. T., Amankwah, E. K., Martinez, D., Williams, S., van Ommen, C. H. & Goldenberg, N. A. Jan 1 2017 In : Thrombosis and Haemostasis. 117, 6, p. 1199-1207 9 p.

Research output: Research - peer-reviewReview article

Pulmonary Embolism
Pulmonary Artery
Thrombosis
Pediatrics
Therapeutics

Recommendations for future research in relation to pediatric pulmonary embolism: Communication from the SSC of the ISTH

Biss, T. T., Rajpurkar, M., Williams, S., van Ommen, C. H., Chan, A. K. C. & Goldenberg, N. A. Jan 1 2017 (Accepted/In press) In : Journal of Thrombosis and Haemostasis.

Research output: Research - peer-reviewArticle

Pulmonary Embolism
Pediatrics

Recommendations for standardized risk factor definitions in pediatric hospital-acquired venous thromboembolism to inform future prevention trials: communication from the SSC of the ISTH

Branchford, B. R., Mahajerin, A., Raffini, L., Chalmers, E., van Ommen, C. H., Chan, A. K. C., Goldenberg, N. A. & for the Subcommittee on Pediatric/Neonatal Hemostasis and Thrombosis Nov 1 2017 In : Journal of Thrombosis and Haemostasis. 15, 11, p. 2274-2278 5 p.

Research output: Research - peer-reviewArticle

Risk factors for hospital-associated venous thromboembolism in critically ill children following cardiothoracic surgery or therapeutic cardiac catheterisation

Atchison, C. M., Amankwah, E., Wilhelm, J., Arlikar, S., Branchford, B. R., Stock, A., Streiff, M., Takemoto, C., Ayala, I., Everett, A., Stapleton, G., Jacobs, M. L., Jacobs, J. P. & Goldenberg, N. A. Nov 8 2017 (Accepted/In press) In : Cardiology in the Young. p. 1-9 9 p.

Research output: Research - peer-reviewArticle

Venous Thromboembolism
Cardiac Catheterization
Critical Illness
Therapeutics
Odds Ratio

Shunt Failure-Risk Factors and Outcomes: An Analysis of The Society of Thoracic Surgeons Congenital Heart Surgery Database

Do, N., Hill, K. D., Wallace, A. S., Vricella, L., Cameron, D., Quintessenza, J., Goldenberg, N., Mavroudis, C., Karl, T., Pasquali, S. K., Jacobs, J. P. & Jacobs, M. L. 2017 (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Research - peer-reviewArticle

Thoracic Surgery
Databases
Pulmonary Artery
Odds Ratio
Arteries
2016

Bivariate evaluation of thromboembolism and bleeding in clinical trials of anticoagulants in patients with atrial fibrillation

Kittelson, J. M., Steg, P. G., Halperin, J. L., Goldenberg, N. A., Schulman, S., Spyropoulos, A. C., Kessler, C. M., Turpie, A. G. G., Cutler, N. R. & Hiatt, W. R. Sep 1 2016 In : Thrombosis and Haemostasis. 116, 3, p. 544-553 10 p.

Research output: Research - peer-reviewArticle

Thromboembolism
Anticoagulants
Atrial Fibrillation
Clinical Trials
Hemorrhage

Guidance for the use of thrombolytic therapy for the treatment of venous thromboembolism

Vedantham, S., Piazza, G., Sista, A. K. & Goldenberg, N. A. Jan 1 2016 In : Journal of Thrombosis and Thrombolysis. 41, 1, p. 68-80 13 p.

Research output: Research - peer-reviewArticle

Thrombolytic Therapy
Venous Thromboembolism
Therapeutics
Pulmonary Embolism
Venous Thrombosis

Impact of high-risk thrombophilia status on recurrence among children with a first non-central-venous-catheter-associated VTE: an observational multicentre cohort study

Limperger, V., Kenet, G., Goldenberg, N. A., Heller, C., Holzhauer, S., Junker, R., Klostermeier, U. C., Knoefler, R., Kurnik, K., Krümpel, A., Mesters, R., Stach, M., Young, G. & Nowak-Göttl, U. Oct 1 2016 In : British Journal of Haematology. 175, 1, p. 133-140 8 p.

Research output: Research - peer-reviewArticle

Thrombophilia
Venous Thromboembolism
Multicenter Studies
Cohort Studies
Catheters

Inter-Rater Reliability of the CASCADE Criteria: Challenges in Classifying Arteriopathies

Bernard, T. J., Beslow, L. A., Manco-Johnson, M. J., Armstrong-Wells, J., Boada, R., Weitzenkamp, D., Hollatz, A., Poisson, S., Amlie-Lefond, C., Lo, W., DeVeber, G., Goldenberg, N. A., Dowling, M. M., Roach, E. S., Fullerton, H. J., Benseler, S. M., Jordan, L. C., Kirton, A. & Ichord, R. N. Oct 1 2016 In : Stroke. 47, 10, p. 2443-2449 7 p.

Research output: Research - peer-reviewArticle

Stroke
Confidence Intervals
Pediatrics
Neuroimaging
Recurrence

Pediatric arterial ischemic stroke: Epidemiology, risk factors, and management

Felling, R. J., Sun, L. R., Maxwell, E. C., Goldenberg, N. & Bernard, T. Oct 11 2016 (Accepted/In press) In : Blood Cells, Molecules, and Diseases.

Research output: Research - peer-reviewArticle

Risk Management
Epidemiology
Stroke
Pediatrics
Newborn Infant
2015

Development of a new risk score for hospital-associated venous thromboembolism in critically-ill children not undergoing cardiothoracic surgery

Arlikar, S. J., Atchison, C. M., Amankwah, E. K., Ayala, I. A., Barrett, L. A., Branchford, B. R., Streiff, M. B., Takemoto, C. M. & Goldenberg, N. A. Oct 1 2015 In : Thrombosis Research. 136, 4, p. 717-722 6 p.

Research output: Research - peer-reviewArticle

Venous Thromboembolism
Critical Illness
Odds Ratio
Confidence Intervals
Pediatric Intensive Care Units

Enhanced Infrastructure for Optimizing the Design and Execution of Clinical Trials and Longitudinal Cohort Studies in the Era of Precision Medicine

Goldenberg, N. A., Daniels, S. R., Mourani, P. M., Hamblin, F., Stowe, A., Powell, S., Ford, D. E. & Ellen, J. 2015 (Accepted/In press) In : Journal of Pediatrics.

Research output: Research - peer-reviewArticle

Child Health Services
Medical Informatics
Precision Medicine
Translational Medical Research
National Institutes of Health (U.S.)

Hospital-associated venous thromboembolism in pediatrics: A systematic review and meta-analysis of risk factors and risk-assessment models

Mahajerin, A., Branchford, B. R., Amankwah, E. K., Raffini, L., Chalmers, E., van Ommen, C. H. & Goldenberg, N. A. Aug 5 2015 In : Haematologica. 100, 8, p. 1045-1050 6 p.

Research output: Research - peer-reviewArticle

Venous Thromboembolism
Meta-Analysis
Pediatrics
Case-Control Studies
Pediatric Hospitals

Improving evidence on anticoagulant therapies for venous thromboembolism in children: Key challenges and opportunities

Goldenberg, N. A., Takemoto, C. M., Yee, D. L., Kittelson, J. M. & Massicotte, M. P. Dec 10 2015 In : Blood. 126, 24, p. 2541-2547 7 p.

Research output: Research - peer-reviewArticle

Venous Thromboembolism
Anticoagulants
Pediatrics
Therapeutics
Randomized Controlled Trials

Multicenter randomized controlled trial on Duration of Therapy for Thrombosis in Children and Young Adults (the Kids-DOTT trial): Pilot/feasibility phase findings

Goldenberg, N. A. , Abshire, T. , Blatchford, P. J. , Fenton, L. Z. , Halperin, J. L. , Hiatt, W. R. , Kessler, C. M. , Kittelson, J. M. , Manco-Johnson, M. J. , Spyropoulos, A. C. , Steg, P. G. , Stence, N. V. , Turpie, A. G. G. , Schulman, S. , Punzalan, R. , Wang, M. , Jaffray, J. , Young, G. , Rajpurkar, M. , Carpenter, S. & 22 others Diab, Y., Verdun, N., Tarango, C., Acharya, S., Torres, M., Kucine, N., Mitchell, B., Shah, N., Thornburg, C., Takemoto, C., Kulkarni, R., O'Brien, S., Haley, K., Recht, M., Knoll, C., Thornburg, C., Geddis, A., Ahuja, S., Simpson, M., Srivaths, L., Journeycake, J. & Zia, A. Sep 1 2015 In : Journal of Thrombosis and Haemostasis. 13, 9, p. 1597-1605 9 p.

Research output: Research - peer-reviewArticle

Random Allocation
Young Adult
Thrombosis
Randomized Controlled Trials
Therapeutics

New developments in pediatric venous thromboembolism and anticoagulation, including the target-specific oral anticoagulants

Lyle, C. A., Sidonio, R. F. & Goldenberg, N. A. Feb 21 2015 In : Current Opinion in Pediatrics. 27, 1, p. 18-25 8 p.

Research output: Research - peer-reviewArticle

Venous Thromboembolism
Anticoagulants
Pediatrics
Safety
Research

UNBLOCK: An open-label, dose-finding, pharmacokinetic and safety study of bivalirudin in children with deep vein thrombosis

O'Brien, S. H., Yee, D. L., Lira, J., Goldenberg, N. A. & Young, G. Sep 1 2015 In : Journal of Thrombosis and Haemostasis. 13, 9, p. 1615-1622 8 p.

Research output: Research - peer-reviewArticle

Venous Thrombosis
Pharmacokinetics
Safety
bivalirudin
Partial Thromboplastin Time

Updates in pediatric venous thromboembolism

Gillespie, M. A., Lyle, C. A. & Goldenberg, N. A. Jul 1 2015 In : Current Opinion in Hematology. 22, 5, p. 413-419 7 p.

Research output: Research - peer-reviewArticle

Venous Thromboembolism
Pediatrics
Clinical Trials
Therapeutics
Dalteparin
2014

Development of a new risk score for hospital-associated venous thromboembolism in noncritically ill children: Findings from a large single-institutional case-control study

Atchison, C. M., Arlikar, S., Amankwah, E., Ayala, I., Barrett, L., Branchford, B. R., Streiff, M., Takemoto, C. & Goldenberg, N. A. Oct 1 2014 In : Journal of Pediatrics. 165, 4, p. 793-798 6 p.

Research output: Research - peer-reviewArticle

Venous Thromboembolism
Case-Control Studies
Central Venous Catheters
Length of Stay
Infection

Epidemiology, etiology, and _ i pathophysiology of infection-associated 7 venous thromboembolism in children

Sharathkumar, A. A., Goldenberg, N. A. & Chan, A. K. C. Jan 1 2014 Pediatric Thrombotic Disorders. Cambridge University Press, p. 88-106 19 p.

Research output: ResearchChapter

Venous Thromboembolism
Bacterial Infections
Epidemiology
Thrombosis
Infection

Hospital-associated venous thromboembolism in children: Incidence and clinical characteristics

Takemoto, C. M., Sohi, S., Desai, K., Bharaj, R., Khanna, A., McFarland, S., Klaus, S., Irshad, A., Goldenberg, N. A., Strouse, J. J. & Streiff, M. B. Feb 2014 In : Journal of Pediatrics. 164, 2, p. 332-338 7 p.

Research output: Research - peer-reviewArticle

Venous Thromboembolism
Incidence
Hospitalization
Pediatrics

Influence of factor 5 rs6025 and factor 2 rs1799963 mutation on inhibitor development in patients with hemophilia A - An Israeli-German multicenter database study

Kenet, G., Bidlingmaier, C., Bogdanova, N., Ettingshausen, C. E., Goldenberg, N., Gutsche, S., Halimeh, S., Holzhauer, S., Kurnik, K., Limperger, V., Junker, R. & Nowak-Göttl, U. 2014 In : Thrombosis Research. 133, 4, p. 544-549 6 p.

Research output: Research - peer-reviewArticle

Hemophilia A
Multicenter Studies
Databases
Mutation
Israel

Multicenter dose-finding and efficacy and safety outcomes in neonates and children treated with dalteparin for acute venous thromboembolism

O'Brien, S. H., Kulkarni, R., Wallace, A., Hamblin, F., Burr, S. & Goldenberg, N. A. Nov 1 2014 In : Journal of Thrombosis and Haemostasis. 12, 11, p. 1822-1825 4 p.

Research output: Research - peer-reviewArticle

Dalteparin
Venous Thromboembolism
Newborn Infant
Safety
Low Molecular Weight Heparin

New anticoagulants in children: A review of recent studies and a look to the future

Young, G. & Goldenberg, N. A. Jan 1 2014 Pediatric Thrombotic Disorders. Cambridge University Press, p. 200-206 7 p.

Research output: ResearchChapter

Anticoagulants
Venous Thromboembolism
Incidence
Therapeutics
Fibrinolytic Agents

Pediatric thrombophilia evaluation: Considerations for primary and secondary venous thromboembolism prevention

Nowak-Gottl, U., Kenet, G. & Goldenberg, N. A. Jan 1 2014 Pediatric Thrombotic Disorders. Cambridge University Press, p. 133-141 9 p.

Research output: ResearchChapter

Thrombophilia
Venous Thromboembolism
Pediatrics
Newborn Infant
Recurrence

Pediatric thrombotic disorders

Goldenberg, N. A. & Manco-Johnson, M. J. Jan 1 2014 Cambridge University Press. 235 p.

Research output: ResearchBook

Thrombosis
Pediatrics
Intracranial Thrombosis
Thromboembolism
Stroke

Preface

Goldenberg, N. A. & Manco-Johnson, M. J. Jan 1 2014 In : Unknown Journal. p. ix

Research output: Research - peer-reviewArticle

Pediatrics
book
hematology
student
Venous Thromboembolism
Venous Thromboembolism
Proteomics
Mass Spectrometry
Biomarkers
Stroke

Risk factors for hospital-sssociated venous thromboembolism in the neonatal intensive care unit

Amankwah, E. K., Atchison, C. M., Arlikar, S., Ayala, I., Barrett, L., Branchford, B. R., Streiff, M., Takemoto, C. & Goldenberg, N. A. 2014 In : Thrombosis Research. 134, 2, p. 305-309 5 p.

Research output: Research - peer-reviewArticle

Neonatal Intensive Care Units
Venous Thromboembolism
Odds Ratio
Critical Illness
Multivariate Analysis

The postthrombotic syndrome: Evidence-based prevention, diagnosis, and treatment strategies: A scientific statement from the American heart association

Kahn, S. R., Comerota, A. J., Cushman, M., Evans, N. S., Ginsberg, J. S., Goldenberg, N. A., Gupta, D. K., Prandoni, P., Vedantham, S., Walsh, M. E. & Weitz, J. I. 2014 In : Circulation. 130, 18, p. 1636-1661 26 p.

Research output: Research - peer-reviewArticle

Postthrombotic Syndrome
American Heart Association
Epidemiology
Delivery of Health Care

Thrombosis and thrombophilia in children

Goldenberg, N. Nov 1 2014 In : Clinical Advances in Hematology and Oncology. 12, 11, p. 773-776 4 p.

Research output: Research - peer-reviewArticle

Thrombophilia
Anticoagulants
Thrombosis

Venous thromboembolism

Lyle, C. & Goldenberg, N. Jan 1 2014 Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care. Springer-Verlag London Ltd, p. 3235-3255 21 p.

Research output: ResearchChapter

Venous Thromboembolism
Critical Care
Heart Diseases
Therapeutics
Critical Illness
2013

Acute prognostic factors for post-thrombotic syndrome in children with Limb DVT: A Bi-institutional cohort study

Lyle, C. A., Gibson, E., Lovejoy, A. E. & Goldenberg, N. A. Jan 2013 In : Thrombosis Research. 131, 1, p. 37-41 5 p.

Research output: Research - peer-reviewArticle

Venous Thrombosis
Cohort Studies
Extremities
Prothrombin Time
beta 2-Glycoprotein I

Antithrombotic therapies. anticoagulation and thrombolysis.

Goel, R., Vedantham, S. & Goldenberg, N. A. Dec 2013 In : Pediatric Clinics of North America. 60, 6, p. 1463-1474 12 p.

Research output: Research - peer-reviewArticle

Therapeutics
Thrombolytic Therapy
Critical Illness
Venous Thrombosis
Clinical Trials

Arteriopathy, D-Dimer, and risk of poor neurologic outcome in childhood-onset arterial ischemic stroke

Goldenberg, N. A., Jenkins, S., Jack, J., Armstrong-Wells, J., Fenton, L. Z., Stence, N. V., Oleszek, J., Boada, R., Wilkening, G. N., Wilkinson, C., Soep, J. B., Miyamoto, S. D., Bajaj, L., Mourani, P. M., Manco-Johnson, M. J. & Bernard, T. J. May 2013 In : Journal of Pediatrics. 162, 5

Research output: Research - peer-reviewArticle

Nervous System
Stroke
fibrin fragment D
Intracranial Hemorrhages
Cohort Studies

Balancing risk and benefit in venous thromboembolism trials: Concept for a bivariate endpoint trial design and analytic approach

Kittelson, J. M., Spyropoulos, A. C., Halperin, J. L., Kessler, C. M., Schulman, S., Steg, G., Turpie, A. G. G., Cutler, N. R., Hiatt, W. R. & Goldenberg, N. A. Aug 2013 In : Journal of Thrombosis and Haemostasis. 11, 8, p. 1443-1448 6 p.

Research output: Research - peer-reviewArticle

Venous Thromboembolism
Hemorrhage
Thromboembolism
Anticoagulants
Therapeutics

Cardiac findings and long-term thromboembolic outcomes following pulmonary embolism in children: A combined retrospective-prospective inception cohort study

Hancock, H. S., Wang, M., Gist, K. M., Gibson, E., Miyamoto, S. D., Mourani, P. M., Manco-Johnson, M. J. & Goldenberg, N. A. Jun 2013 In : Cardiology in the Young. 23, 3, p. 344-352 9 p.

Research output: Research - peer-reviewArticle

Pulmonary Embolism
Cohort Studies
Pediatrics
Therapeutics
Right Ventricular Dysfunction

Elevated lipoprotein (a), small apolipoprotein (a), and the risk of arterial ischemic stroke in North American children

Goldenberg, N. A., Bernard, T. J., Hillhouse, J., Armstrong-Wells, J., Galinkin, J., Knapp-Clevenger, R., Jacobson, L., Marcovina, S. M. & Manco-Johnson, M. J. 2013 In : Haematologica. 98, 5, p. 802-807 6 p.

Research output: Research - peer-reviewArticle

Apoprotein(a)
Lipoprotein(a)
Stroke
Kringles
Fibrinolysis

Experimental pediatric arterial ischemic stroke model reveals sex-specific estrogen signaling

Herson, P. S., Bombardier, C. G., Parker, S. M., Shimizu, T., Klawitter, J., Klawitter, J., Quillinan, N., Exo, J. L., Goldenberg, N. A. & Traystman, R. J. Mar 2013 In : Stroke. 44, 3, p. 759-763 5 p.

Research output: Research - peer-reviewArticle

Estrogens
Stroke
Pediatrics
Middle Cerebral Artery Infarction
Ischemia

Moderate aplastic anemia in children: Preliminary outcomes for treatment versus observation from a single-institutional experience

Brock, K., Goldenberg, N., Graham, D. K., Liang, X. & Hays, T. Mar 2013 In : Journal of Pediatric Hematology/Oncology. 35, 2, p. 148-152 5 p.

Research output: Research - peer-reviewArticle

Aplastic Anemia
Observation
Therapeutics
Immunosuppressive Agents
Myelodysplastic Syndromes

Overweight and obesity are increased in childhood-onset cerebrovascular disease

Pearson, V., Ruzas, C., Krebs, N. F., Goldenberg, N. A., Manco-Johnson, M. J. & Bernard, T. J. Apr 2013 In : Journal of Child Neurology. 28, 4, p. 517-519 3 p.

Research output: Research - peer-reviewArticle

Cerebrovascular Disorders
Intracranial Thrombosis
Pediatric Obesity
Obesity
Stroke

Role of reduced ADAMTS13 in arterial ischemic stroke: A Pediatric Cohort Study

Lambers, M., Goldenberg, N. A., Kenet, G., Kirkham, F. J., Manner, D., Bernard, T., Mesters, R. M., Junker, R., Stoll, M. & Nowak-Göttl, U. Jan 2013 In : Annals of Neurology. 73, 1, p. 58-64 7 p.

Research output: Research - peer-reviewArticle

Cohort Studies
Stroke
Pediatrics
Blood Group Antigens
Thrombospondin 1
Thrombosis
Cohort Studies
Stroke
Pediatrics
Research

The methylenetetrahydrofolate reductase polymorphism (MTHFR c.677C > T) and elevated plasma homocysteine levels in a U.S. pediatric population with incident thromboembolism

Joachim, E., Goldenberg, N. A., Bernard, T. J., Armstrong-Wells, J., Stabler, S. & Manco-Johnson, M. J. Aug 2013 In : Thrombosis Research. 132, 2, p. 170-174 5 p.

Research output: Research - peer-reviewArticle

Methylenetetrahydrofolate Reductase (NADPH2)
Thromboembolism
Venous Thromboembolism
Homocysteine
Pediatrics