Neeraj Sharma

Instructor

20132019
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 5 Similar Profiles
Cystic Fibrosis Medicine & Life Sciences
Cystic Fibrosis Transmembrane Conductance Regulator Medicine & Life Sciences
Epithelial Cells Medicine & Life Sciences
Proteins Medicine & Life Sciences
Receptor, Melanocortin, Type 3 Medicine & Life Sciences
Sweat Medicine & Life Sciences
RNA Isoforms Medicine & Life Sciences
RNA Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2013 2019

Correlating cystic fibrosis transmembrane conductance regulator function with clinical features to inform precision treatment of cystic fibrosis

McCague, A. F., Raraigh, K. S., Pellicore, M. J., Davis-Marcisak, E. F., Evans, T. A., Han, S. T., Lu, Z., Joynt, A. T., Sharma, N., Castellani, C., Collaco, M., Corey, M., Lewis, M. H., Penland, C. M., Rommens, J. M., Stephenson, A. L., Sosnay, P. R. & Cutting, G. R., May 1 2019, In : American journal of respiratory and critical care medicine. 199, 9, p. 1116-1126 11 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Cystic Fibrosis
Genotype
Sweat
Chlorides

Decreased mRNA and protein stability of W1282X limits response to modulator therapy

Aksit, M. A., Bowling, A. D., Evans, T. A., Joynt, A. T., Osorio, D., Patel, S., West, N. E., Merlo, C., Sosnay, P. R., Cutting, G. R. & Sharma, N., Jan 1 2019, In : Journal of Cystic Fibrosis.

Research output: Contribution to journalArticle

Protein Stability
RNA Stability
Nose
Cystic Fibrosis Transmembrane Conductance Regulator
RNA

Capitalizing on the heterogeneous effects of CFTR nonsense and frameshift variants to inform therapeutic strategy for cystic fibrosis

Sharma, N., Evans, T. A., Pellicore, M. J., Davis, E., Aksit, M. A., McCague, A. F., Joynt, A. T., Lu, Z., Han, S. T., Anzmann, A. F., Lam, A. T. N., Thaxton, A., West, N. E., Merlo, C., Gottschalk, L. B., Raraigh, K. S., Sosnay, P. R., Cotton, C. U. & Cutting, G. R., Nov 1 2018, In : PLoS Genetics. 14, 11, e1007723.

Research output: Contribution to journalArticle

cystic fibrosis
Cystic Fibrosis
Nonsense Codon
therapeutics
protein

Functional Assays Are Essential for Interpretation of Missense Variants Associated with Variable Expressivity

Raraigh, K. S., Han, S. T., Davis, E., Evans, T. A., Pellicore, M. J., McCague, A. F., Joynt, A. T., Lu, Z., Atalar, M., Sharma, N., Sheridan, M., Sosnay, P. R. & Cutting, G. R., Jun 7 2018, In : American Journal of Human Genetics. 102, 6, p. 1062-1077 16 p.

Research output: Contribution to journalArticle

Cystic Fibrosis
Virulence
Molecular Pathology
Human Genome
Genomics

Systematic Computational Identification of Variants That Activate Exonic and Intronic Cryptic Splice Sites

Lee, M., Roos, P., Sharma, N., Atalar, M., Evans, T. A., Pellicore, M. J., Davis, E., Lam, A. T. N., Stanley, S. E., Khalil, S. E., Solomon, G. M., Walker, D., Raraigh, K. S., Vecchio-Pagan, B., Armanios, M. & Cutting, G. R., May 4 2017, In : American Journal of Human Genetics. 100, 5, p. 751-765 15 p.

Research output: Contribution to journalArticle

RNA Splice Sites
Cystic Fibrosis
Dyskeratosis Congenita
Genes