Ned Sacktor

Professor

1985 …2020

Research output per year

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Research Output

2017

Predictors and Impact of Self-Reported Suboptimal Effort on Estimates of Prevalence of HIV-Associated Neurocognitive Disorders

Levine, A. J., Martin, E., Sacktor, N., Munro, C. & Becker, J., Jun 1 2017, In : Journal of acquired immune deficiency syndromes. 75, 2, p. 203-210 8 p.

Research output: Contribution to journalArticle

Prevalence and Correlates of Persistent HIV-1 RNA in Cerebrospinal Fluid During Antiretroviral Therapy

CHARTER Group, Jan 1 2017, In : The Journal of infectious diseases. 215, 1, p. 105-113 9 p.

Research output: Contribution to journalArticle

The association between physical activity and cognition in men with and without HIV infection

Monroe, A. K., Zhang, L., Jacobson, L. P., Plankey, M. W., Brown, T. T., Miller, E. N., Martin, E., Becker, J. T., Levine, A. J., Ragin, A. & Sacktor, N. C., Sep 2017, In : HIV Medicine. 18, 8, p. 555-563 9 p.

Research output: Contribution to journalArticle

The BIOCARD Index: A Summary Measure to Predict Onset of Mild Cognitive Impairment

the BIOCARD Research Team, Apr 7 2017, (Accepted/In press) In : Alzheimer Disease and Associated Disorders.

Research output: Contribution to journalArticle

Transcriptome analyses identify key cellular factors associated with HIV-1-associated neuropathogenesis in infected men

Venkatachari, N. J., Jain, S., Walker, L., Bivalkar-Mehla, S., Chattopadhyay, A., Bar-Joseph, Z., Rinaldo, C., Ragin, A., Seaberg, E., Levine, A., Becker, J., Martin, E., Sacktor, N. & Ayyavoo, V., Mar 13 2017, In : AIDS. 31, 5, p. 623-633 11 p.

Research output: Contribution to journalArticle

2016

A Comparison of Five Brief Screening Tools for HIV-Associated Neurocognitive Disorders in the USA and South Africa

Joska, J. A., Witten, J., Thomas, K. G., Robertson, C., Casson-Crook, M., Roosa, H., Creighton, J., Lyons, J., McArthur, J. & Sacktor, N. C., Aug 1 2016, In : AIDS and behavior. 20, 8, p. 1621-1631 11 p.

Research output: Contribution to journalArticle

Association of midlife smoking status with change in processing speed and mental flexibility among HIV-seropositive and HIV-seronegative older men: the Multicenter AIDS Cohort Study

Akhtar-Khaleel, W. Z., Cook, R. L., Shoptaw, S., Miller, E. N., Sacktor, N., Surkan, P., Becker, J., Teplin, L. A., Beyth, R. J., Price, C. & Plankey, M., Nov 26 2016, (Accepted/In press) In : Journal of NeuroVirology. p. 1-11 11 p.

Research output: Contribution to journalArticle

Cognitive Impairment Among Older Individuals with HIV Infection

Saylor, D. & Sacktor, N., Jun 1 2016, In : Current Geriatrics Reports. 5, 2, p. 63-70 8 p.

Research output: Contribution to journalArticle

Cortical brain atrophy and intra-individual variability in neuropsychological test performance in HIV disease

Hines, L. J., Miller, E. N., Hinkin, C. H., Alger, J. R., Barker, P., Goodkin, K., Martin, E. M., Maruca, V., Ragin, A., Sacktor, N., Sanders, J., Selnes, O., Becker, J. T. & for the Multicenter AIDS Cohort Study, T. M. AIDS. C. S., Sep 1 2016, In : Brain Imaging and Behavior. 10, 3, p. 640-651 12 p.

Research output: Contribution to journalArticle

HIV-associated neurocognitive disorder - Pathogenesis and prospects for treatment

Saylor, D., Dickens, A. M., Sacktor, N., Haughey, N., Slusher, B., Pletnikov, M., Mankowski, J. L., Brown, A., Volsky, D. J. & McArthur, J. C., Apr 1 2016, In : Nature Reviews Neurology. 12, 4, p. 234-248 15 p.

Research output: Contribution to journalReview article

Hypothetical preclinical Alzheimer disease groups and longitudinal cognitive change

Soldan, A., Pettigrew, C., Cai, Q., Wang, M. C., Moghekar, A. R., O'Brien, R. J., Selnes, O. A., Albert, M. S., Rodzon, B., Gottesman, R., Sacktor, N., McKhann, G., Turner, S., Farrington, L., Grega, M., Rudow, G., D'Agostino, D., Rudow, S., Miller, M., Mori, S. & 21 others, Ratnanather, T., Brown, T., Chi, H., Kolasny, A., Oishi, K., Reigel, T., Younes, L., Spangler, A., Scherer, R., Shade, D., Ervin, A., Jones, J., Toepfner, M., Parlett, L., Patterson, A., Mohammed, A., Lu, D., Troncoso, J., Crain, B., Pletnikova, O. & Fisher, K., Jun 1 2016, In : JAMA Neurology. 73, 6, p. 698-705 8 p.

Research output: Contribution to journalArticle

International neurocognitive normative study: neurocognitive comparison data in diverse resource-limited settings: AIDS Clinical Trials Group A5271

For The Aids Clinical Trials Group, Aug 1 2016, In : Journal of neurovirology. 22, 4, p. 472-478 7 p.

Research output: Contribution to journalArticle

Longitudinal Changes over 10 Years in Free Testosterone among HIV-Infected and HIV-Uninfected Men

for the Multicenter AIDS Cohort Study (MACS), Jan 1 2016, In : Journal of acquired immune deficiency syndromes. 71, 1, p. 57-64 8 p.

Research output: Contribution to journalArticle

Lower CSF Aβ is associated with HAND in HIV-infected adults with a family History of Dementia

CNS HIV Antiretroviral Therapy Effects Research CHARTER Group, Jul 1 2016, In : Current HIV research. 14, 4, p. 324-330 7 p.

Research output: Contribution to journalArticle

Prevalence of HIV-associated neurocognitive disorders in the Multicenter AIDS Cohort Study

Sacktor, N., Skolasky, R. L., Seaberg, E., Munro, C., Becker, J. T., Martin, E., Ragin, A., Levine, A. & Miller, E., Jan 26 2016, In : Neurology. 86, 4, p. 334-340 7 p.

Research output: Contribution to journalArticle

Proceedings from the NIMH symposium on “NeuroAIDS in Africa: neurological and neuropsychiatric complications of HIV”

Buch, S., Chivero, E. T., Hoare, J., Jumare, J., Nakasujja, N., Mudenda, V., Paul, R., Kanmogne, G. D., Sacktor, N., Wood, C., Royal, W. & Joseph, J., Jul 29 2016, (Accepted/In press) In : Journal of NeuroVirology. p. 1-4 4 p.

Research output: Contribution to journalArticle

Reward, attention, and HIV-related risk in HIV+ individuals

Anderson, B. A., Kronemer, S. I., Rilee, J. J., Sacktor, N. & Marvel, C. L., Aug 1 2016, In : Neurobiology of Disease. 92, p. 157-165 9 p.

Research output: Contribution to journalArticle

Visceral fat is associated with brain structure independent of human immunodeficiency virus infection status

Lake, J. E., Popov, M., Post, W. S., Palella, F. J., Sacktor, N., Miller, E. N., Brown, T. T. & Becker, J. T., Dec 15 2016, (Accepted/In press) In : Journal of NeuroVirology. p. 1-9 9 p.

Research output: Contribution to journalArticle

2015

Accelerated longitudinal gait speed decline in HIV-infected older men

for the Multicenter AIDS Cohort Study, Dec 1 2015, In : Journal of acquired immune deficiency syndromes. 70, 4, p. 370-376 7 p.

Research output: Contribution to journalArticle

Adiponectin and interleukin-6, but not adipose tissue, are associated with worse neurocognitive function in HIV-infected men

Lake, J. E., Vo, Q. T., Jacobson, L. P., Sacktor, N., Miller, E. N., Post, W. S., Becker, J. T., Palella, F. J., Ragin, A., Martin, E., Munro, C. A. & Brown, T. T., Jan 1 2015, In : Antiviral therapy. 20, 2, p. 235-244 10 p.

Research output: Contribution to journalArticle

Cohort Profile: Recruitment cohorts in the neuropsychological substudy of the Multicenter AIDS Cohort Study

Becker, J. T., Kingsley, L. A., Molsberry, S., Reynolds, S., Aronow, A., Levine, A. J., Martin, E., Miller, E. N., Munro, C. A., Ragin, A., Sacktor, N. & Selnes, O. A., Oct 1 2015, In : International journal of epidemiology. 44, 5, p. 1506-1516 11 p., dyu092.

Research output: Contribution to journalArticle

Mixed membership trajectory models of cognitive impairment in the multicenter AIDS cohort study

Molsberry, S. A., Lecci, F., Kingsley, L., Junker, B., Reynolds, S., Goodkin, K., Levine, A. J., Martin, E., Miller, E. N., Munro, C. A., Ragin, A., Sacktor, N. & Becker, J. T., Mar 27 2015, In : AIDS. 29, 6, p. 713-721 9 p.

Research output: Contribution to journalArticle

Network neurodegeneration in Alzheimer's disease via MRI based shape diffeomorphometry and high-field atlasing

BIOCARD Research Team, Jan 1 2015, In : Frontiers in Bioengineering and Biotechnology. 3, MAY, 54.

Research output: Contribution to journalArticle

Neurocognitive change in the era of HIV combination antiretroviral therapy: The longitudinal CHARTER study

Heaton, R. K., Franklin, D. R., Deutsch, R., Letendre, S., Ellis, R. J., Casaletto, K., Marquine, M. J., Woods, S. P., Vaida, F., Atkinson, J. H., Marcotte, T. D., McCutchan, J. A., Collier, A. C., Marra, C. M., Clifford, D. B., Gelman, B. B., Sacktor, N., Morgello, S., Simpson, D. M., Abramson, I. & 4 others, Gamst, A. C., Fennema-Notestine, C., Smith, D. M. & Grant, I., Feb 1 2015, In : Clinical Infectious Diseases. 60, 3, p. 473-480 8 p.

Research output: Contribution to journalArticle

Relationship of medial temporal lobe atrophy, APOE genotype, and cognitive reserve in preclinical Alzheimer's disease

the BIOCARD Research Team, Jul 1 2015, In : Human Brain Mapping. 36, 7, p. 2826-2841 16 p.

Research output: Contribution to journalArticle

Reply to Haddow et al

Heaton, R. K., Franklin, D. R., Deutsch, R., Letendre, S. L., Ellis, R. J., Casaletto, K., Marquine, M. J., Woods, S. P., Vaida, F., Atkinson, J. H., Marcotte, T. D., McCutchan, J. A., Collier, A. C., Marra, C. M., Clifford, D. B., Gelman, B. B., Sacktor, N., Morgello, S., Simpson, D. M., Abramson, I. & 4 others, Gamst, A., Fennema-Notestine, C., Smith, D. M. & Grant, I., May 1 2015, In : Clinical Infectious Diseases. 60, 9, p. 1442-1443 2 p.

Research output: Contribution to journalLetter

2014

Cognitive changes preceding clinical symptom onset of mild cognitive impairment and relationship to apoe genotype

Albert, M., Soldan, A., Gottesman, R., McKhann, G., Sacktor, N., Farrington, L., Grega, M., Turner, R., Lu, Y., Li, S., Wang, M. C. & Selnes, O., Jan 1 2014, In : Current Alzheimer Research. 11, 8, p. 773-784 12 p.

Research output: Contribution to journalArticle

Evolving clinical phenotypes in HIV-associated neurocognitive disorders

Sacktor, N. & Robertson, K., Jan 1 2014, In : Current opinion in HIV and AIDS. 9, 6, p. 517-520 4 p.

Research output: Contribution to journalReview article

HIV subtype is not associated with dementia among individuals with moderate and advanced immunosuppression in Kampala, Uganda

Sacktor, N., Nakasujja, N., Redd, A. D., Manucci, J., Laeyendecker, O., Wendel, S. K., Porcella, S. F., Martens, C., Bruno, D., Skolasky, R. L., Okonkwo, O. C., Robertson, K., Musisi, S., Katabira, E. & Quinn, T. C., Jun 2014, In : Metabolic Brain Disease. 29, 2, p. 261-268 8 p.

Research output: Contribution to journalArticle

Identification of putative biomarkers for HIV-associated neurocognitive impairment in the CSF of HIV-infected patients under cART therapy determined by mass spectrometry

Bora, A., Mohien, C. U., Chaerkady, R., Chang, L., Moxley, R., Sacktor, N., Haughey, N., McArthur, J. C., Cotter, R., Nath, A. & Graham, D. R., Oct 21 2014, In : Journal of neurovirology. 20, 5, p. 457-465 9 p.

Research output: Contribution to journalArticle

Impact of minocycline on cerebrospinal fluid markers of oxidative stress, neuronal injury, and inflammation in HIV-seropositive individuals with cognitive impairment

Sacktor, N., Miyahara, S., Evans, S., Schifitto, G., Cohen, B., Haughey, N., Drewes, J. L., Graham, D., Zink, M. C., Anderson, C., Nath, A., Pardo, C. A., McCarthy, S., Hosey, L. & Clifford, D., Dec 12 2014, In : Journal of neurovirology. 20, 6, p. 620-626 7 p.

Research output: Contribution to journalArticle

No association between Apoε4 alleles, HIV infection, age, neuropsychological outcome, or death

Becker, J. T., Martinson, J. J., Penugonda, S., Kingsley, L., Molsberry, S., Reynolds, S., Aronow, A., Goodkin, K., Levine, A., Martin, E., Miller, E. N., Munro, C. A., Ragin, A. & Sacktor, N., Jan 1 2014, In : Journal of neurovirology. 21, 1, p. 24-31 8 p.

Research output: Contribution to journalArticle

Polyamines: Predictive biomarker for HIV-associated neurocognitive disorders

Merali, S., Barrero, C. A., Sacktor, N. C., Haughey, N. J., Datta, P. K., Langford, D. & Khalili, K., 2014, In : Journal of AIDS and Clinical Research. 5, 6

Research output: Contribution to journalArticle

Randomized trial of central nervous system-targeted antiretrovirals for HIV-associated neurocognitive disorder

Ellis, R. J., Letendre, S., Vaida, F., Haubrich, R., Heaton, R. K., Sacktor, N., Clifford, D. B., Best, B. M., May, S., Umlauf, A., Cherner, M., Sanders, C., Ballard, C., Simpson, D. M., Jay, C. & McCutchan, J. A., Jan 1 2014, In : Clinical Infectious Diseases. 58, 7, p. 1015-1022 8 p.

Research output: Contribution to journalArticle

Regional brain distribution of translocator protein using [ 11C]DPA-713 PET in individuals infected with HIV

Coughlin, J. M., Wang, Y., Ma, S., Yue, C., Kim, P. K., Adams, A. V., Roosa, H. V., Gage, K. L., Stathis, M., Rais, R., Rojas, C., McGlothan, J. L., Watkins, C. C., Sacktor, N., Guilarte, T. R., Zhou, Y., Sawa, A., Slusher, B. S., Caffo, B., Kassiou, M. & 2 others, Endres, C. J. & Pomper, M. G., Jun 2014, In : Journal of neurovirology. 20, 3, p. 219-232 14 p.

Research output: Contribution to journalArticle

The longitudinal and interactive effects of HIV status, stimulant use, and host genotype upon neurocognitive functioning

Levine, A. J., Reynolds, S., Cox, C., Miller, E. N., Sinsheimer, J. S., Becker, J. T., Martin, E. & Sacktor, N., Jun 2014, In : Journal of neurovirology. 20, 3, p. 243-257 15 p.

Research output: Contribution to journalArticle

2013

A lipid storage-like disorder contributes to cognitive decline in HIV-infected subjects

Bandaru, V. V. R., Mielke, M. M., Sacktor, N., McArthur, J. C., Grant, I., Letendre, S., Chang, L., Wojna, V., Pardo, C., Calabresi, P., Munsaka, S. & Haughey, N. J., Oct 22 2013, In : Neurology. 81, 17, p. 1492-1499 8 p.

Research output: Contribution to journalArticle

A novel computerized functional assessment for human immunodeficiency virus-associated neurocognitive disorder

Rosenthal, L. S., Skolasky, R. L., Moxley, R. T., Roosa, H. V., Selnes, O. A., Eschman, A., McArthur, J. C. & Sacktor, N., Oct 2013, In : Journal of neurovirology. 19, 5, p. 432-441 10 p.

Research output: Contribution to journalArticle

Brain reserve: HIV morbidity and mortality

Reinhard, M. J., Satz, P., Seines, O. A., Sacktor, N., Cohen, B. A., Becker, J. T. & Miller, E. N., Jan 1 2013, Cognitive Reserve: Theory and Applications. Taylor and Francis, p. 207-218 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Detection of anti-tat antibodies in CSF of individuals with HIV-associated neurocognitive disorders

Bachani, M., Sacktor, N., McArthur, J. C., Nath, A. & Rumbaugh, J., Feb 18 2013, In : Journal of neurovirology. 19, 1, p. 82-88 7 p.

Research output: Contribution to journalArticle

Global NeuroAIDS roundtable

Joseph, J., Achim, C. L., Boivin, M. J., Brew, B. J., Clifford, D. B., Colosi, D. A., Ellis, R. J., Heaton, R. K., Gallo-Diop, A., Grant, I., Kanmogne, G. D., Kumar, M., Letendre, S., Marcotte, T. D., Nath, A., Pardo, C. A., Paul, R. H., Pulliam, L., Robertson, K., Royal, W. & 6 others, Sacktor, N., Sithinamsuwan, P., Smith, D. M., Valcour, V., Wigdahl, B. & Wood, C., Feb 18 2013, In : Journal of neurovirology. 19, 1, p. 1-9 9 p.

Research output: Contribution to journalReview article

HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors

Rumbaugh, J. A., Bachani, M., Li, W., Butler, T. R., Smith, K. J., Bianchet, M. A., Wang, T., Prendergast, M. A., Sacktor, N. & Nath, A., Jan 1 2013, In : Neurobiology of Disease. 49, 1, p. 169-176 8 p.

Research output: Contribution to journalArticle

Longitudinal neuropsychological test performance among HIV seropositive individuals in Uganda

Sacktor, N., Nakasujja, N., Okonkwo, O., Skolasky, R. L., Robertson, K., Musisi, S. & Katabira, E., Feb 18 2013, In : Journal of neurovirology. 19, 1, p. 48-56 9 p.

Research output: Contribution to journalArticle

Long-term predictive value of the Framingham Risk Score for Stroke in HIV-positive vs HIV-negative men

Mateen, F. J., Post, W. S., Sacktor, N., Abraham, A. G., Becker, J. T., Smith, B. R., Detels, R., Martin, E., Phair, J. P. & Shinohara, R. T., Dec 10 2013, In : Neurology. 81, 24, p. 2094-2102 9 p.

Research output: Contribution to journalArticle

Neuropsychological test performance before and after HIV-1 seroconversion: The Multicenter AIDS Cohort Study

Vo, Q. T., Cox, C., Li, X., Jacobson, L. P., McKaig, R., Sacktor, N., Selnes, O. A., Martin, E., Becker, J. T. & Miller, E. N., Feb 18 2013, In : Journal of neurovirology. 19, 1, p. 24-31 8 p.

Research output: Contribution to journalArticle

Older individuals with HIV infection have greater memory deficits than younger individuals

Tan, I. L., Smith, B. R., Hammond, E., Vornbrock-Roosa, H., Creighton, J., Selnes, O., McArthur, J. C. & Sacktor, N., Dec 1 2013, In : Journal of neurovirology. 19, 6, p. 531-536 6 p.

Research output: Contribution to journalArticle

Randomized trial of minocycline in the treatment of HIV-associated cognitive impairment

Nakasujja, N., Miyahara, S., Evans, S., Lee, A., Musisi, S., Katabira, E., Robertson, K., Ronald, A., Clifford, D. B. & Sacktor, N., Jan 8 2013, In : Neurology. 80, 2, p. 196-202 7 p.

Research output: Contribution to journalArticle