Ned Sacktor

Professor

1985 …2020

Research output per year

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Research Output

Cross-sectional analysis of cognitive function using multivariate normative comparisons in men with HIV disease

Wang, Z., Molsberry, S. A., Cheng, Y., Kingsley, L., Levine, A. J., Martin, E., Munro, C. A., Ragin, A., Rubin, L. H., Sacktor, N., Seaberg, E. C. & Becker, J. T., Nov 15 2019, In : AIDS. 33, 14, p. 2115-2124 10 p.

Research output: Contribution to journalArticle

CSF antiretroviral drug penetrance and the treatment of HIV-associated psychomotor slowing

Sacktor, N., Tarwater, P. M., Skolasky, R. L., McArthur, J. C., Selnes, O. A., Becker, J., Cohen, B. & Miller, E. N., Aug 14 2001, In : Neurology. 57, 3, p. 542-544 3 p.

Research output: Contribution to journalArticle

Dendritic spine injury induced by the 8-hydroxy metabolite of efavirenz

Tovar-y-Romo, L. B., Bumpus, N. N., Pomerantz, D., Avery, L. B., Sacktor, N., McArthur, J. C. & Haughey, N. J., Dec 1 2012, In : Journal of Pharmacology and Experimental Therapeutics. 343, 3, p. 696-703 8 p.

Research output: Contribution to journalArticle

Depression symptoms and cognitive function among individuals with advanced HIV infection initiating HAART in Uganda

Nakasujja, N., L Skolasky, R., Musisi, S., Allebeck, P., Robertson, K., Ronald, A., Katabira, E., Clifford, D. B. & Sacktor, N., Jun 10 2010, In : BMC psychiatry. 10, 44.

Research output: Contribution to journalArticle

Detection of anti-tat antibodies in CSF of individuals with HIV-associated neurocognitive disorders

Bachani, M., Sacktor, N., McArthur, J. C., Nath, A. & Rumbaugh, J., Feb 18 2013, In : Journal of neurovirology. 19, 1, p. 82-88 7 p.

Research output: Contribution to journalArticle

Developing neuroprotective strategies for treatment of HIV-associated neurocognitive dysfunction

Rumbaugh, J. A., Steiner, J., Sacktor, N. & Nath, A., Sep 29 2008, In : Future HIV Therapy. 2, 3, p. 271-280 10 p.

Research output: Contribution to journalReview article

Diabetes, insulin resistance, and dementia among HIV-1-infected patients

Valcour, V. G., Shikuma, C. M., Shiramizu, B. T., Williams, A. E., Watters, M. R., Poff, P. W., Grove, J. S., Selnes, O. A. & Sacktor, N. C., Jan 1 2005, In : Journal of Acquired Immune Deficiency Syndromes. 38, 1, p. 31-36 6 p.

Research output: Contribution to journalArticle

Differences in cognitive function between women and men with HIV

Maki, P. M., Rubin, L., Springer, G., Seaberg, E. C., Sacktor, N., Miller, E. N., Valcour, V., Young, M. A., Becker, J. T. & Martin, E. M., Sep 1 2018, In : Journal of Acquired Immune Deficiency Syndromes. 79, 1, p. 101-107 7 p.

Research output: Contribution to journalArticle

Differences in Neurocognitive Impairment among HIV-Infected Latinos in the United States

Marquine, M. J., Heaton, A., Johnson, N., Rivera-Mindt, M., Cherner, M., Bloss, C., Hulgan, T., Umlauf, A., Moore, D. J., Fazeli, P., Morgello, S., Franklin, D., Letendre, S., Ellis, R., Collier, A. C., Marra, C. M., Clifford, D. B., Gelman, B. B., Sacktor, N., Simpson, D. & 3 others, McCutchan, J. A., Grant, I. & Heaton, R. K., Feb 1 2018, In : Journal of the International Neuropsychological Society. 24, 2, p. 163-175 13 p.

Research output: Contribution to journalArticle

Effect of ageing on neurocognitive function by stage of HIV infection: Evidence from the Multicenter AIDS Cohort Study

Goodkin, K., Miller, E. N., Cox, C., Reynolds, S., Becker, J. T., Martin, E., Selnes, O. A., Ostrow, D. G. & Sacktor, N., 2017, (Accepted/In press) In : The Lancet HIV.

Research output: Contribution to journalArticle

Effect of HIV Subtype and Antiretroviral Therapy on HIV-Associated Neurocognitive Disorder Stage in Rakai, Uganda

Sacktor, N., Saylor, D., Nakigozi, G., Nakasujja, N., Robertson, K., Grabowski, M. K., Kisakye, A., Batte, J., Mayanja, R., Anok, A., Gray, R. H. & Wawer, M. J., Jun 1 2019, In : Journal of acquired immune deficiency syndromes. 81, 2, p. 216-223 8 p.

Research output: Contribution to journalArticle

Effects of comorbidity burden and age on brain integrity in HIV

CHARTER Study Group, Jun 1 2019, In : AIDS (London, England). 33, 7, p. 1175-1185 11 p.

Research output: Contribution to journalArticle

Effects of subperineurial injections of very-long-chain and medium-chain fatty acids into rat sciatic nerve

Sacktor, N. C., Griffin, J., Moser, A. B. & Moser, H. W., Aug 1 1986, In : Neurochemical Pathology. 5, 1, p. 71-83 13 p.

Research output: Contribution to journalArticle

Elevated Depressive Symptoms Are a Stronger Predictor of Executive Dysfunction in HIV-Infected Women Than in Men

Rubin, L., Springer, G., Martin, E. M., Seaberg, E. C., Sacktor, N., Levine, A., Valcour, V. G., Young, M. A., Becker, J. T. & Maki, P. M., Jul 1 2019, In : Journal of acquired immune deficiency syndromes (1999). 81, 3, p. 274-283 10 p.

Research output: Contribution to journalArticle

Erratum: Characterization of nitrotyrosine-modified proteins in cerebrospinal fluid (Clinical Proteomics DOI: 10.1007/s12014-010-9041-4)

Beasley, A. S., Anderson, C., McArthur, J., Sacktor, N., Nath, A. & Cotter, R. J., Jun 1 2010, In : Clinical Proteomics. 6, 1-2, p. 42-44 3 p.

Research output: Contribution to journalComment/debate

Evaluating the accuracy of self-report for the diagnosis of HIV-associated neurocognitive disorder (HAND): defining “symptomatic” versus “asymptomatic” HAND

The CNS HIV Anti-Retroviral Therapy Effects Research (CHARTER) Group, Feb 1 2017, In : Journal of neurovirology. 23, 1, p. 67-78 12 p.

Research output: Contribution to journalArticle

Evaluation of HIV RNA and markers of immune activation as predictors of HIV-associated dementia

Sevigny, J. J., Albert, S. M., McDermott, M. P., McArthur, J. C., Sacktor, N., Conant, K., Schifitto, G., Selnes, O. A., Stern, Y., McClernon, D. R., Palumbo, D., Kieburtz, K., Riggs, G., Cohen, B., Epstein, L. G. & Marder, K., Dec 14 2004, In : Neurology. 63, 11, p. 2084-2090 7 p.

Research output: Contribution to journalArticle

Evolution of HIV dementia with HIV infection

Nath, A., Schiess, N., Venkatesan, A., Rumbaugh, J., Sacktor, N. & Mcarthur, J., Feb 1 2008, In : International Review of Psychiatry. 20, 1, p. 25-31 7 p.

Research output: Contribution to journalReview article

Evolving clinical phenotypes in HIV-associated neurocognitive disorders

Sacktor, N. & Robertson, K., Jan 1 2014, In : Current opinion in HIV and AIDS. 9, 6, p. 517-520 4 p.

Research output: Contribution to journalReview article

Exploring the relationship of macrophage colony-stimulating factor levels on neuroaxonal metabolism and cognition during chronic human immunodeficiency virus infection

Lentz, M. R., Degaonkar, M., Mohamed, M. A., Kim, H., Conant, K., Halpern, E. F., Sacktor, N., Barker, P. B. & Pomper, M. G., Oct 1 2010, In : Journal of neurovirology. 16, 5, p. 368-376 9 p.

Research output: Contribution to journalArticle

Factor analysis of proton MR spectroscopic imaging data in HIV infection: Metabolite-derived factors help identify infection and dementia

Mohamed, M. A., Lentz, M. R., Lee, V., Halpern, E. F., Sacktor, N., Selnes, O., Barker, P. B. & Pomper, M. G., Feb 1 2010, In : RADIOLOGY. 254, 2, p. 577-586 10 p.

Research output: Contribution to journalArticle

Factor in AIDS dementia complex trial design: Results and lessons from the abacavir trial

Brew, B. J., Halman, M., Catalan, J., Sacktor, N., Price, R. W., Brown, S., Atkinson, H., Clifford, D. B., Simpson, D., Torres, G., Hall, C., Power, C., Marder, K., McArthur, J. C., Symonds, W. & Romero, C., Mar 30 2007, In : PLoS Clinical Trials. 2, 3, e13.

Research output: Contribution to journalArticle

Factors affecting brain structure in men with HIV disease in the post-HAART era

Becker, J. T., Maruca, V., Kingsley, L. A., Sanders, J. M., Alger, J. R., Barker, P. B., Goodkin, K., Martin, E., Miller, E. N., Ragin, A., Sacktor, N. & Selnes, O., Feb 1 2012, In : Neuroradiology. 54, 2, p. 113-121 9 p.

Research output: Contribution to journalArticle

Factors associated with incident human immunodeficiency virus-dementia

Stern, Y., McDermott, M. P., Albert, S., Palumbo, D., Selnes, O. A., McArthur, J., Sacktor, N., Schifitto, G., Kieburtz, K., Epstein, L. & Marder, K. S., Jan 1 2001, In : Archives of neurology. 58, 3, p. 473-479 7 p.

Research output: Contribution to journalArticle

Open Access

Frequency of and risk factors for HIV dementia in an HIV clinic in sub-Saharan Africa

Wong, M. H., Robertson, K., Nakasujja, N., Skolasky, R., Musisi, S., Katabira, E., McArthur, J. C., Ronald, A. & Sacktor, N., Jan 1 2007, In : Neurology. 68, 5, p. 350-355 6 p.

Research output: Contribution to journalArticle

Frequency of and risk factors for HIV dementia in an HIV clinic in sub-Saharan Africa [6]

Wong, M. H. & Sacktor, N., Jul 1 2007, In : Neurology. 69, 4, 1 p.

Research output: Contribution to journalLetter

Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study

for the CHARTER Study Group, Jun 2017, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 174, 4, p. 413-426 14 p.

Research output: Contribution to journalArticle

Genome-wide association study of neurocognitive impairment and dementia in HIV-infected adults

Levine, A. J., Service, S., Miller, E. N., Reynolds, S. M., Singer, E. J., Shapshak, P., Martin, E. M., Sacktor, N., Becker, J. T., Jacobson, L. P., Thompson, P. & Freimer, N., Sep 1 2012, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 159 B, 6, p. 669-683 15 p.

Research output: Contribution to journalArticle

Global NeuroAIDS roundtable

Joseph, J., Achim, C. L., Boivin, M. J., Brew, B. J., Clifford, D. B., Colosi, D. A., Ellis, R. J., Heaton, R. K., Gallo-Diop, A., Grant, I., Kanmogne, G. D., Kumar, M., Letendre, S., Marcotte, T. D., Nath, A., Pardo, C. A., Paul, R. H., Pulliam, L., Robertson, K., Royal, W. & 6 others, Sacktor, N., Sithinamsuwan, P., Smith, D. M., Valcour, V., Wigdahl, B. & Wood, C., Feb 18 2013, In : Journal of neurovirology. 19, 1, p. 1-9 9 p.

Research output: Contribution to journalReview article

Headache prevalence and its functional impact among HIV-infected adults in rural Rakai District, Uganda

Sohail, S., Nakigozi, G., Anok, A., Batte, J., Kisakye, A., Mayanja, R., Nakasujja, N., Robertson, K. R., Gray, R. H., Wawer, M. J., Sacktor, N. & Saylor, D., Apr 15 2019, In : Journal of neurovirology. 25, 2, p. 248-253 6 p.

Research output: Contribution to journalArticle

Heterogeneity in neurocognitive change trajectories among people with HIV starting antiretroviral therapy in Rakai, Uganda

Rubin, L. H., Saylor, D., Nakigozi, G., Nakasujja, N., Robertson, K., Kisakye, A., Batte, J., Mayanja, R., Anok, A., Lofgren, S. M., Boulware, D. R., Dastgheyb, R., Reynolds, S. J., Quinn, T. C., Gray, R. H., Wawer, M. J. & Sacktor, N., Dec 1 2019, In : Journal of neurovirology. 25, 6, p. 800-813 14 p.

Research output: Contribution to journalArticle

Higher frequency of dementia in older HIV-1 individuals: The Hawaii aging with HIV-1 cohort

Valcour, V., Shikuma, C., Shiramizu, B., Watters, M., Poff, P., Selnes, O., Holck, P., Grove, J. & Sacktor, N., Sep 14 2004, In : Neurology. 63, 5, p. 822-827 6 p.

Research output: Contribution to journalArticle

HIV-1 reverse transcriptase sequence in plasma and cerebrospinal fluid of patients with AIDS dementia complex treated with Abacavir

Lanier, E. R., Sturge, G., McClernon, D., Brown, S., Halman, M., Sacktor, N., McArthur, J., Atkinson, J. H., Clifford, D., Price, R. W., Simpson, D., Torres, G., Catalan, J., Marder, K., Power, C., Hall, C., Romero, C. & Brew, B., Apr 13 2001, In : AIDS. 15, 6, p. 747-751 5 p.

Research output: Contribution to journalArticle

HIV-associated cognitive impairment before and after the advent of combination therapy

Sacktor, N., McDermott, M. P., Marder, K., Schifitto, G., Selnes, O. A., McArthur, J. C., Stern, Y., Albert, S., Palumbo, D., Kieburtz, K., De Marcaida, J. A., Cohen, B. & Epstein, L., Jan 1 2002, In : Journal of neurovirology. 8, 2, p. 136-142 7 p.

Research output: Contribution to journalArticle

HIV-associated cognitive impairment in sub-Saharan Africa - The potential effect of clade diversity

Sacktor, N., Nakasujja, N., Robertson, K. & Clifford, D. B., Aug 1 2007, In : Nature Clinical Practice Neurology. 3, 8, p. 436-443 8 p.

Research output: Contribution to journalReview article

HIV-associated dementia and aging

Valcour, V. G. & Sacktor, N., Dec 1 2002, In : Journal of Mental Health and Aging. 8, 4, p. 295-306 12 p.

Research output: Contribution to journalReview article

HIV-associated neurocognitive disorder - Pathogenesis and prospects for treatment

Saylor, D., Dickens, A. M., Sacktor, N., Haughey, N., Slusher, B., Pletnikov, M., Mankowski, J. L., Brown, A., Volsky, D. J. & McArthur, J. C., Apr 1 2016, In : Nature Reviews Neurology. 12, 4, p. 234-248 15 p.

Research output: Contribution to journalReview article

HIV-associated neurologic disease incidence changes: Multicenter AIDS Cohort Study, 1990-1998

Sacktor, N., Lyles, R. H., Skolasky, R., Kleeberger, C., Selnes, O. A., Miller, E. N., Becker, J. T., Cohen, B. & McArthur, J. C., Jan 23 2001, In : Neurology. 56, 2, p. 257-260 4 p.

Research output: Contribution to journalArticle

Open Access

HIV disease and diabetes interact to affect brain white matter hyperintensities and cognition

Wu, M., Fatukasi, O., Yang, S., Alger, J., Barker, P. B., Hetherington, H., Kim, T., Levine, A., Martin, E., Munro, C. A., Parrish, T., Ragin, A., Sacktor, N., Seaberg, E. & Becker, J. T., Jan 1 2018, In : AIDS. 32, 13, p. 1803-1810 8 p.

Research output: Contribution to journalArticle

HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors

Rumbaugh, J. A., Bachani, M., Li, W., Butler, T. R., Smith, K. J., Bianchet, M. A., Wang, T., Prendergast, M. A., Sacktor, N. & Nath, A., Jan 1 2013, In : Neurobiology of Disease. 49, 1, p. 169-176 8 p.

Research output: Contribution to journalArticle

HIV subtype D is associated with dementia, compared with subtype A, in immunosuppressed individuals at risk of cognitive impairment in Kampala, Uganda

Sacktor, N., Nakasujja, N., Skolasky, R. L., Rezapour, M., Robertson, K., Musisi, S., Katabira, E., Ronald, A., Clifford, D. B., Laeyendecker, O. & Quinn, T. C., Sep 1 2009, In : Clinical Infectious Diseases. 49, 5, p. 780-786 7 p.

Research output: Contribution to journalArticle

HIV subtype is not associated with dementia among individuals with moderate and advanced immunosuppression in Kampala, Uganda

Sacktor, N., Nakasujja, N., Redd, A. D., Manucci, J., Laeyendecker, O., Wendel, S. K., Porcella, S. F., Martens, C., Bruno, D., Skolasky, R. L., Okonkwo, O. C., Robertson, K., Musisi, S., Katabira, E. & Quinn, T. C., Jun 2014, In : Metabolic Brain Disease. 29, 2, p. 261-268 8 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus-associated dementia

McArthur, J. C., Sacktor, N. & Selnes, O., Jan 1 1999, In : Seminars in Neurology. 19, 2, p. 129-150 22 p.

Research output: Contribution to journalReview article

Human immunodeficiency virus-associated dementia: An evolving disease

McArthur, J. C., Haughey, N., Gartner, S., Conant, K., Pardo, C., Nath, A. & Sacktor, N., Apr 2003, In : Journal of neurovirology. 9, 2, p. 205-221 17 p.

Research output: Contribution to journalReview article

Human Immunodeficiency Virus-Associated Dementia: Clinical Aspects, Biology, and Treatment

Venkataramana, A. & Sacktor, N., Dec 1 2008, Dimentias. Duyckaerts, C. & Litvan, I. (eds.). p. 799-806 8 p. (Handbook of Clinical Neurology; vol. 89).

Research output: Chapter in Book/Report/Conference proceedingChapter

Human immunodeficiency virus-associated neurocognitive disorders mind the gap

McArthur, J. C., Steiner, J., Sacktor, N. & Nath, A., Jun 1 2010, In : Annals of neurology. 67, 6, p. 699-714 16 p.

Research output: Contribution to journalReview article

Human Immunodeficiency Virus-associated Neurocognitive Impairment in Diverse Resource-limited Settings

AIDS Clinical Trials Group, May 1 2019, In : Clinical Infectious Diseases. 68, 10, p. 1733-1738 6 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus neurological complications: An overview of the Ugandan experience

Nakasujja, N., Musisi, S., Robertson, K., Wong, M., Sacktor, N. & Ronald, A., Dec 1 2005, In : Journal of neurovirology. 11, SUPPL. 3, p. 26-29 4 p.

Research output: Contribution to journalReview article

Human Immunodeficiency Virus Type 1 and Tuberculosis Coinfection in Multinational, Resource-limited Settings: Increased neurological dysfunction

5199 Study Team; for the AIDS Clinical Trials Group, May 1 2019, In : Clinical Infectious Diseases. 68, 10, p. 1739-1746 8 p.

Research output: Contribution to journalArticle