Natasha E Zachara

Associate Professor

19962019
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Fingerprint Dive into the research topics where Natasha E Zachara is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Acetylglucosamine Medicine & Life Sciences
Glycosylation Medicine & Life Sciences
Post Translational Protein Processing Medicine & Life Sciences
Proteins Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Mitochondrial Proteins Medicine & Life Sciences
Nuclear Proteins Medicine & Life Sciences
Cells Chemical Compounds

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Research Output 1996 2019

Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90

Sager, R. A., Woodford, M. R., Backe, S. J., Makedon, A. M., Baker-Williams, A. J., DiGregorio, B. T., Loiselle, D. R., Haystead, T. A., Zachara, N. E., Prodromou, C., Bourboulia, D., Schmidt, L. S., Linehan, W. M., Bratslavsky, G. & Mollapour, M., Jan 29 2019, In : Cell Reports. 26, 5, p. 1344-1356.e5

Research output: Contribution to journalArticle

Phosphorylation
Molecular Chaperones
Casein Kinase II
Ubiquitination
Adenosine Triphosphatases

BioSITe: A Method for Direct Detection and Quantitation of Site-Specific Biotinylation

Kim, D. I., Cutler, J. A., Na, C-H., Reckel, S., Renuse, S., Madugundu, A. K., Tahir, R., Goldschmidt, H. L., Reddy, K. L., Huganir, R. L., Wu, X., Zachara, N. E., Hantschel, O. & Pandey, A., Feb 2 2018, In : Journal of Proteome Research. 17, 2, p. 759-769 11 p.

Research output: Contribution to journalArticle

Biotinylation
Biotin
Technology
Labeling
Proteins

Critical observations that shaped our understanding of the function(s) of intracellular glycosylation (O-GlcNAc)

Zachara, N. E., Dec 1 2018, In : FEBS Letters. 592, 23, p. 3950-3975 26 p.

Research output: Contribution to journalReview article

Glycosylation
Proteins
Acetylglucosamine
Monosaccharides
Mucins

Modulation of O-GlcNAc levels in the liver impacts acetaminophen-induced liver injury by affecting protein adduct formation and glutathione synthesis

McGreal, S. R., Bhushan, B., Walesky, C., McGill, M. R., Lebofsky, M., Kandel, S. E., Winefield, R. D., Jaeschke, H., Zachara, N. E., Zhang, Z., Tan, E. P., Slawson, C. & Apte, U., Apr 1 2018, In : Toxicological Sciences. 162, 2, p. 599-610 12 p.

Research output: Contribution to journalArticle

Acetaminophen
Liver
Glutathione
Modulation
Wounds and Injuries

New use for CETSA: monitoring innate immune receptor stability via post-translational modification by OGT

Drake, W. R., Hou, C. W., Zachara, N. E. & Grimes, C. L., Apr 18 2018, (Accepted/In press) In : Journal of Bioenergetics and Biomembranes. p. 1-10 10 p.

Research output: Contribution to journalArticle

Immunologic Monitoring
Post Translational Protein Processing
Nucleotides
Hot Temperature
Proteins