Natasha E Zachara

Associate Professor

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Research Output 1996 2018

BioSITe: A Method for Direct Detection and Quantitation of Site-Specific Biotinylation

Kim, D. I., Cutler, J. A., Na, C-H., Reckel, S., Renuse, S., Madugundu, A. K., Tahir, R., Goldschmidt, H. L., Reddy, K. L., Huganir, R. L., Wu, X., Zachara, N. E., Hantschel, O. & Pandey, A., Feb 2 2018, In : Journal of Proteome Research. 17, 2, p. 759-769 11 p.

Research output: Contribution to journalArticle


Critical observations that shaped our understanding of the function(s) of intracellular glycosylation (O-GlcNAc)

Zachara, N. E., Dec 1 2018, In : FEBS Letters. 592, 23, p. 3950-3975 26 p.

Research output: Contribution to journalReview article


Modulation of O-GlcNAc levels in the liver impacts acetaminophen-induced liver injury by affecting protein adduct formation and glutathione synthesis

McGreal, S. R., Bhushan, B., Walesky, C., McGill, M. R., Lebofsky, M., Kandel, S. E., Winefield, R. D., Jaeschke, H., Zachara, N. E., Zhang, Z., Tan, E. P., Slawson, C. & Apte, U., Apr 1 2018, In : Toxicological Sciences. 162, 2, p. 599-610 12 p.

Research output: Contribution to journalArticle

Wounds and Injuries

New use for CETSA: monitoring innate immune receptor stability via post-translational modification by OGT

Drake, W. R., Hou, C. W., Zachara, N. E. & Grimes, C. L., Apr 18 2018, (Accepted/In press) In : Journal of Bioenergetics and Biomembranes. p. 1-10 10 p.

Research output: Contribution to journalArticle

Immunologic Monitoring
Post Translational Protein Processing
Hot Temperature

O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis

Taparra, K., Wang, H., Malek, R., Lafargue, A., Barbhuiya, M. A., Wang, X., Simons, B. W., Ballew, M., Nugent, K., Groves, J., Williams, R. D., Shiraishi, T., Verdone, J., Yildirir, G., Henry, R., Zhang, B., Wong, J., Wang, K-H., Nelkin, B. D., Pienta, K. & 3 othersFelsher, D., Zachara, N. E. & Tran, P. T., Nov 1 2018, In : The Journal of clinical investigation. 128, 11, p. 4924-4937 14 p.

Research output: Contribution to journalArticle

Biosynthetic Pathways