Natasha E Zachara

Associate Professor

19962018
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 9 Similar Profiles
Acetylglucosamine Medicine & Life Sciences
Glycosylation Medicine & Life Sciences
Post Translational Protein Processing Medicine & Life Sciences
Proteins Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Mitochondrial Proteins Medicine & Life Sciences
Nuclear Proteins Medicine & Life Sciences
Cells Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1996 2018

BioSITe: A Method for Direct Detection and Quantitation of Site-Specific Biotinylation

Kim, D. I., Cutler, J. A., Na, C-H., Reckel, S., Renuse, S., Madugundu, A. K., Tahir, R., Goldschmidt, H. L., Reddy, K. L., Huganir, R. L., Wu, X., Zachara, N. E., Hantschel, O. & Pandey, A., Feb 2 2018, In : Journal of Proteome Research. 17, 2, p. 759-769 11 p.

Research output: Contribution to journalArticle

Biotinylation
Biotin
Technology
Labeling
Proteins

Critical observations that shaped our understanding of the function(s) of intracellular glycosylation (O-GlcNAc)

Zachara, N. E., Dec 1 2018, In : FEBS Letters. 592, 23, p. 3950-3975 26 p.

Research output: Contribution to journalReview article

Glycosylation
Proteins
Acetylglucosamine
Monosaccharides
Mucins

Modulation of O-GlcNAc levels in the liver impacts acetaminophen-induced liver injury by affecting protein adduct formation and glutathione synthesis

McGreal, S. R., Bhushan, B., Walesky, C., McGill, M. R., Lebofsky, M., Kandel, S. E., Winefield, R. D., Jaeschke, H., Zachara, N. E., Zhang, Z., Tan, E. P., Slawson, C. & Apte, U., Apr 1 2018, In : Toxicological Sciences. 162, 2, p. 599-610 12 p.

Research output: Contribution to journalArticle

Acetaminophen
Liver
Glutathione
Modulation
Wounds and Injuries

New use for CETSA: monitoring innate immune receptor stability via post-translational modification by OGT

Drake, W. R., Hou, C. W., Zachara, N. E. & Grimes, C. L., Apr 18 2018, (Accepted/In press) In : Journal of Bioenergetics and Biomembranes. p. 1-10 10 p.

Research output: Contribution to journalArticle

Immunologic Monitoring
Post Translational Protein Processing
Nucleotides
Hot Temperature
Proteins

O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis

Taparra, K., Wang, H., Malek, R., Lafargue, A., Barbhuiya, M. A., Wang, X., Simons, B. W., Ballew, M., Nugent, K., Groves, J., Williams, R. D., Shiraishi, T., Verdone, J., Yildirir, G., Henry, R., Zhang, B., Wong, J., Wang, K-H., Nelkin, B. D., Pienta, K. & 3 othersFelsher, D., Zachara, N. E. & Tran, P. T., Nov 1 2018, In : The Journal of clinical investigation. 128, 11, p. 4924-4937 14 p.

Research output: Contribution to journalArticle

Hexosamines
Biosynthetic Pathways
Carcinogenesis
Lung
Glycosylation