Namandje N Bumpus

Associate Professor

20042019
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Fingerprint Dive into the research topics where Namandje N Bumpus is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Tenofovir Medicine & Life Sciences
efavirenz Medicine & Life Sciences
HIV Medicine & Life Sciences
Cytochrome P-450 CYP3A Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Pharmacokinetics Medicine & Life Sciences
Cytochrome P-450 Enzyme System Medicine & Life Sciences
HIV-1 Medicine & Life Sciences

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Research Output 2004 2019

Biotransformation and bioactivation reactions–2018 literature highlights

Khojasteh, S. C., Bumpus, N. N., Driscoll, J. P., Miller, G. P., Mitra, K., Rietjens, I. M. C. M. & Zhang, D., Jan 1 2019, (Accepted/In press) In : Drug Metabolism Reviews.

Research output: Contribution to journalReview article

Biotransformation
Pharmaceutical Preparations
Drug Discovery
Computer Simulation
Toxicology

Drug concentration asymmetry in tissues and plasma for small molecule-related therapeutic modalities

Zhang, D., Hop, C. E. C. A., Patilea-Vrana, G., Gampa, G., Seneviratne, H. K., Unadkat, J. D., Kenny, J. R., Nagapudi, K., Di, L., Zhou, L., Zak, M., Wright, M. R., Bumpus, N. N., Zang, R., Liu, X., Lai, Y. & Cyrus Khojasteh, S., Jan 1 2019, In : Drug Metabolism and Disposition. 47, 10, p. 1122-1135 14 p.

Research output: Contribution to journalArticle

Open Access
Pharmaceutical Preparations
Therapeutics
Pharmacokinetics
Pharmacologic Actions
Proton-Motive Force

Efavirenz and efavirenz-like compounds activate human, murine, and macaque hepatic IRE1a-XBP1

Heck, C. J. S., Hamlin, A. N. & Bumpus, N. N., Feb 1 2019, In : Molecular Pharmacology. 95, 2, p. 185-195 11 p.

Research output: Contribution to journalArticle

efavirenz
Macaca
Inositol
Protein Splicing
Hepatocytes

Genetic variation of kinases and activation of nucleotide analog reverse transcriptase inhibitor tenofovir

Hamlin, A. N., Tillotson, J. & Bumpus, N. N., Jan 1 2019, In : Pharmacogenomics. 20, 2, p. 105-111 7 p.

Research output: Contribution to journalArticle

Tenofovir
Reverse Transcriptase Inhibitors
Phosphotransferases
Nucleotides
HIV
Tenofovir
Eastern Africa
Pharmacokinetics
HIV
Population