Monica Mugnier

Assistant Professor

20112019
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Research Output 2011 2019

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Article
2019

Developmental competence and antigen switch frequency can be uncoupled in Trypanosoma brucei

McWilliam, K. R., Ivens, A., Morrison, L. J., Mugnier, M. R. & Matthews, K. R., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 45, p. 22774-22782 9 p.

Research output: Contribution to journalArticle

Open Access
Antigenic Variation
Trypanosoma brucei brucei
Mental Competency
Trypanosomiasis
Parasites
2016

A Conserved DNA Repeat Promotes Selection of a Diverse Repertoire of Trypanosoma brucei Surface Antigens from the Genomic Archive

Hovel-Miner, G., Mugnier, M., Goldwater, B., Cross, G. A. M. & Papavasiliou, F. N., May 1 2016, In : PLoS Genetics. 12, 5, e1005994.

Research output: Contribution to journalArticle

variant surface glycoproteins
Trypanosoma brucei
Trypanosoma brucei brucei
Membrane Glycoproteins
surface antigens

Detection of Trypanosoma brucei variant surface glycoprotein switching by magnetic activated cell sorting and flow cytometry

Schulz, D., Mugnier, M., Boothroyd, C. E. & Nina Papavasiliou, F., Oct 19 2016, In : Journal of Visualized Experiments. 2016, 116, e54715.

Research output: Contribution to journalArticle

Trypanosoma Variant Surface Glycoproteins
Glycoproteins
Trypanosoma brucei brucei
Flow cytometry
Membrane Glycoproteins
2015

Bromodomain Proteins Contribute to Maintenance of Bloodstream Form Stage Identity in the African Trypanosome

Schulz, D., Mugnier, M., Paulsen, E. M., Kim, H. S., Chung, C. W. W., Tough, D. F., Rioja, I., Prinjha, R. K., Papavasiliou, F. N. & Debler, E. W., Dec 8 2015, In : PLoS Biology. 13, 12, e1002316.

Research output: Contribution to journalArticle

bloodstream forms
Trypanosomiasis
variant surface glycoproteins
Membrane Glycoproteins
Maintenance

The in vivo dynamics of antigenic variation in Trypanosoma brucei

Mugnier, M., Cross, G. A. M. & Papavasiliou, F. N., Mar 27 2015, In : Science. 347, 6229, p. 1470-1473 4 p.

Research output: Contribution to journalArticle

Antigenic Variation
Trypanosoma brucei brucei
Membrane Glycoproteins
African Trypanosomiasis
Trypanosomiasis
2012

Long-lived bone marrow plasma cells are induced early in response to T cell-independent or T cell-dependent antigens

Bortnick, A., Chernova, I., Quinn, W. J., Mugnier, M., Cancro, M. P. & Allman, D., Jun 1 2012, In : Journal of Immunology. 188, 11, p. 5389-5396 8 p.

Research output: Contribution to journalArticle

Plasma Cells
Bone Marrow Cells
Germinal Center
T-Lymphocytes
Antigens

Telomere Length Affects the Frequency and Mechanism of Antigenic Variation in Trypanosoma brucei

Hovel-Miner, G. A., Boothroyd, C. E., Mugnier, M., Dreesen, O., Cross, G. A. M. & Papavasiliou, F. N., Aug 2012, In : PLoS Pathogens. 8, 8, e1002900.

Research output: Contribution to journalArticle

Antigenic Variation
Trypanosoma brucei brucei
Membrane Glycoproteins
Telomere
Gene Conversion
2011

A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center

Schwickert, T. A., Victora, G. D., Fooksman, D. R., Kamphorst, A. O., Mugnier, M., Gitlin, A. D. & Nussenzweig, M. L. D., Jun 2011, In : Journal of Experimental Medicine. 208, 6, p. 1243-1252 10 p.

Research output: Contribution to journalArticle

Germinal Center
B-Lymphocytes
T-Lymphocytes
Major Histocompatibility Complex
Clone Cells