Miho Iijima

Associate Professor

19982018
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Research Output 1998 2018

A brain-enriched drp1 isoform associates with lysosomes, late endosomes, and the plasma membrane

Itoh, K., Adachi, Y., Yamada, T., Suzuki, T. L., Otomo, T., McBride, H. M., Yoshimori, T., Iijima, M. & Sesaki, H., Jan 1 2018, In : Journal of Biological Chemistry. 293, 30, p. 11809-11822 14 p.

Research output: Contribution to journalArticle

Dynamins
Endosomes
Cell membranes
Lysosomes
Mitochondria

Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease

Yamada, T., Murata, D., Adachi, Y., Itoh, K., Kameoka, S., Igarashi, A., Kato, T., Araki, Y., Huganir, R. L., Dawson, T. M., Yanagawa, T., Okamoto, K., Iijima, M. & Sesaki, H., Jan 1 2018, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Ubiquitination
Liver
Mitochondria
Cullin Proteins

Nuclear PTEN deficiency causes microcephaly with decreased neuronal soma size and increased seizure susceptibility

Igarashi, A., Itoh, K., Yamada, T., Adachi, Y., Kato, T., Murata, D., Sesaki, H. & Iijima, M., Jan 1 2018, In : Journal of Biological Chemistry. 293, 24, p. 9292-9300 9 p.

Research output: Contribution to journalArticle

Microcephaly
Phosphatases
Carisoprodol
Phosphoric Monoester Hydrolases
Seizures

An unstructured loop that is critical for interactions of the stalk domain of Drp1 with saturated phosphatidic acid

Adachi, Y., Iijima, M. & Sesaki, H., Jun 23 2017, (Accepted/In press) In : Small GTPases. p. 1-8 8 p.

Research output: Contribution to journalArticle

Dynamins
Phosphatidic Acids
Proteins
Membranes
Mitochondrial Membranes

Characterization of PTEN mutations in brain cancer reveals that pten mono-ubiquitination promotes protein stability and nuclear localization

Yang, J. M., Schiapparelli, P., Nguyen, H. N., Igarashi, A., Zhang, Q., Abbadi, S., Amzel, L. M., Sesaki, H., Quiñones-Hinojosa, A. & Iijima, M., Mar 6 2017, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Protein Stability
Ubiquitination
Phosphoric Monoester Hydrolases
Brain Neoplasms
PTEN Phosphohydrolase