Michelle Rudek-Renaut

Associate Professor

19992018
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Research Output 1999 2018

Brentuximab vedotin with AVD shows safety, in the absence of strong CYP3A4 inhibitors, in newly diagnosed HIV-associated Hodgkin lymphoma

Rubinstein, P. G., Moore, P. C., Rudek, M. A., Henry, D. H., Ramos, J. C., Ratner, L., Reid, E., Sharon, E. & Noy, A., Mar 13 2018, In : AIDS. 32, 5, p. 605-611 7 p.

Research output: Contribution to journalArticle

Hodgkin Disease
HIV
Safety
Cytochrome P-450 CYP3A
Ritonavir

Muscadine grape skin extract (MPX) in men with biochemically recurrent prostate cancer: A randomized, multicenter, placebo-controlled clinical trial

Paller, C. J. , Zhou, X. C. , Heath, E. I. , Taplin, M. E. , Mayer, T. , Stein, M. N. , Bubley, G. J. , Pili, R. , Hudson, T. , Kakarla, R. , Abbas, M. M. , Anders, N. M. , Dowling, D. , King, S. , Bruns, A. B. , Wagner, W. D. , Drake, C. G. , Antonarakis, E. S. , Eisenberger, M. A. , Denmeade, S. R. & 3 others Rudek, M. A., Rosner, G. L. & Carducci, M. A., Jan 15 2018, In : Clinical Cancer Research. 24, 2, p. 306-315 10 p.

Research output: Contribution to journalArticle

Controlled Clinical Trials
Vitis
Prostatic Neoplasms
Placebos
Skin

Safety and Preliminary Efficacy of Vorinostat With R-EPOCH in High-risk HIV-associated Non-Hodgkin's Lymphoma (AMC-075)

Ramos, J. C., Sparano, J. A., Rudek, M. A., Moore, P. C., Cesarman, E., Reid, E. G., Henry, D., Ratner, L., Aboulafia, D., Lee, J. Y., Ambinder, R. F., Mitsuyasu, R. & Noy, A., Mar 1 2018, In : Clinical Lymphoma, Myeloma and Leukemia. 18, 3, p. 180-190.e2

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Human Herpesvirus 4
Non-Hodgkin's Lymphoma
HIV
Safety

Sorafenib Dose Recommendation in Acute Myeloid Leukemia Based on Exposure-FLT3 Relationship

on behalf of the ETCTN-6745 study team, Jul 1 2018, In : Clinical and Translational Science. 11, 4, p. 435-443 9 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Protein-Tyrosine Kinases
Extracellular Signal-Regulated MAP Kinases
Mitogen-Activated Protein Kinase 6
Metabolites

Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

Kalin, J. H. , Wu, M. , Gomez, A. V. , Song, Y. , Das, J. , Hayward, D. , Adejola, N. , Wu, M. , Panova, I. , Chung, H. J. , Kim, E. , Roberts, H. J. , Roberts, J. M. , Prusevich, P. , Jeliazkov, J. R. , Roy Burman, S. S. , Fairall, L. , Milano, C. , Eroglu, A. , Proby, C. M. & 14 others Dinkova-Kostova, A. T., Hancock, W. W., Gray, J. J., Bradner, J. E., Valente, S., Mai, A., Anders, N. M., Rudek, M. A., Hu, Y., Ryu, B., Schwabe, J. W. R., Mattevi, A., Alani, R. M. & Cole, P. A., Dec 1 2018, In : Nature Communications. 9, 1, 53

Research output: Contribution to journalArticle

cells and cell components
Histone Demethylases
enzyme activity
Histone Deacetylase Inhibitors
gene expression