Research Output 1972 2017

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2017

Generation-6 hydroxyl PAMAM dendrimers improve CNS penetration from intravenous administration in a large animal brain injury model

Zhang, F., Trent Magruder, J., Lin, Y. A., Crawford, T. C., Grimm, J. C., Sciortino, C. M., Wilson, M. A., Blue, M. E., Kannan, S., Johnston, M. V., Baumgartner, W. A. & Kannan, R. M. Mar 10 2017 In : Journal of Controlled Release. 249, p. 173-182 10 p.

Research output: Contribution to journalArticle

Dendrimers
Intravenous Administration
Hydroxyl Radical
Brain Injuries
Brain

Uptake of dendrimer-drug by different cell types in the hippocampus after hypoxic–ischemic insult in neonatal mice: Effects of injury, microglial activation and hypothermia

Nemeth, C. L., Drummond, G. T., Mishra, M. K., Zhang, F., Carr, P., Garcia, M. S., Doman, S., Fatemi, A., Johnston, M. V., Kannan, R. M., Kannan, S. & Wilson, M. A. Oct 1 2017 In : Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 7, p. 2359-2369 11 p.

Research output: Contribution to journalArticle

Dendrimers
Microglia
Hypothermia
Hippocampus
Wounds and Injuries
2016

Cerebral plasticity: Windows of opportunity in the developing brain

Ismail, F. Y., Fatemi, A. & Johnston, M. V. 2016 In : European Journal of Paediatric Neurology.

Research output: Contribution to journalArticle

Brain
Neuronal Plasticity
Critical Period (Psychology)
Pediatrics
Central Nervous System

Cerebral reorganization after hemispherectomy: A DTI study

Meoded, A., Faria, A. V., Hartman, A. L., Jallo, G. I., Mori, S., Johnston, M. V., Huisman, T. A. G. M. & Andrea, P. May 1 2016 In : American Journal of Neuroradiology. 37, 5, p. 924-931 8 p.

Research output: Contribution to journalArticle

Hemispherectomy
Anisotropy
Pathology
Linear Models
Neurosurgical Procedures
Diffusion Tensor Imaging
Ischemia
White Matter
Anisotropy
Wounds and Injuries
Fetal Hypoxia
Asphyxia
Glutamic Acid
Ischemia
Brain Hypoxia-Ischemia
Anoxia
Inflammation
Wounds and Injuries
AMPA Receptors

Glial-Restricted Precursors Protect Neonatal Brain Slices from Hypoxic-Ischemic Cell Death Without Direct Tissue Contact

Sweda, R., Phillips, A. W., Marx, J., Johnston, M. V., Wilson, M. A. & Fatemi, A. Jul 1 2016 In : Stem Cells and Development. 25, 13, p. 975-985 11 p.

Research output: Contribution to journalArticle

Neuroglia
Cell Death
Brain
Anoxia
Stem Cells
Dendrimers
Nanotechnology
Brain Injuries
Canidae
Inflammation
Brain Hypoxia-Ischemia
Induced Hypothermia
Ultrasonography
Brain
Anterior Cerebral Artery
2015

Acute TrkB inhibition rescues phenobarbital-resistant seizures in a mouse model of neonatal ischemia

Kang, S. K., Johnston, M. V. & Kadam, S. D. Nov 1 2015 In : European Journal of Neuroscience. 42, 10, p. 2792-2804 13 p.

Research output: Contribution to journalArticle

Phenobarbital
Seizures
Ischemia
Symporters
Brain Hypoxia-Ischemia

Age- and sex-dependent susceptibility to phenobarbital-resistant neonatal seizures: Role of chloride co-transporters

Kang, S. K., Markowitz, G. J., Kim, S. T., Johnston, M. V. & Kadam, S. D. May 12 2015 In : Frontiers in Cellular Neuroscience. 9, MAY

Research output: Contribution to journalArticle

Symporters
Phenobarbital
Chlorides
Seizures
Bumetanide
Brain Hypoxia-Ischemia
Induced Hypothermia
Homeostasis
Cohort Studies
Newborn Infant

Autism Phenotypes in Tuberous Sclerosis Complex: Diagnostic and Treatment Considerations

Gipson, T. T., Poretti, A., Thomas, E. A., Jenkins, K. T., Desai, S. & Johnston, M. V. Dec 1 2015 In : Journal of Child Neurology. 30, 14, p. 1871-1876 6 p.

Research output: Contribution to journalArticle

Tuberous Sclerosis
Pervasive Child Development Disorders
Autistic Disorder
Phenotype
Intellectual Disability

Correction: Systemic Injection of CD34+ -Enriched Human Cord Blood Cells Modulates Poststroke Neural and Glial Response in a Sex-Dependent Manner in CD1 Mice (Stem Cells and Development (2015) 24, 1 (51-66))

Kadam, S., Chen, H., Markowitz, G. J., Raja, S., George, S., Verina, T., Shotwell, E., Loechelt, B., Johnston, M. V., Kamani, N., Fatemi, A. & Comi, A. M. Apr 1 2015 In : Stem Cells and Development. 24, 7, p. 916 1 p.

Research output: Contribution to journalArticle

Heightened delta power during slow-wave- sleep in patients with rett syndrome associated with poor sleep efficiency

Ammanuel, S., Chan, W. C., Adler, D. A., Lakshamanan, B. M., Gupta, S. S., Ewen, J. B., Johnston, M. V., Marcus, C. L., Naidu, S. & Kadam, S. D. Oct 7 2015 In : PLoS One. 10, 10, e0138113

Research output: Contribution to journalArticle

Rett Syndrome
Sleep
Power (Psychology)
sleep
Electroencephalography

Murine model: maternal administration of stem cells for prevention of prematurity

Lei, J., Firdaus, W., Rosenzweig, J. M., Alrebh, S., Bakhshwin, A., Borbiev, T., Fatemi, A., Blakemore, K., Johnston, M. V. & Burd, I. May 1 2015 In : American Journal of Obstetrics and Gynecology. 212, 5

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Stem Cells
Premature Birth
Inflammation
Brain Injuries
Extracorporeal Membrane Oxygenation
Observational Study
Electroencephalography
Medical Subject Headings
Nervous System Trauma

Ongoing Cerebral Vasculitis During Treatment of Rocky Mountain Spotted Fever

Sun, L. R., Huisman, T. A. G. M., Yeshokumar, A. K. & Johnston, M. V. Nov 1 2015 In : Pediatric Neurology. 53, 5, p. 434-438 5 p.

Research output: Contribution to journalArticle

Rocky Mountain Spotted Fever
Central Nervous System Vasculitis
Infection
Vasculitis
Brain

Peri-Implantation Hormonal Milieu: Elucidating Mechanisms of Adverse Neurodevelopmental Outcomes

Mainigi, M., Rosenzweig, J. M., Lei, J., Mensah, V., Thomaier, L., Talbot, C. C., Olalere, D., Ord, T., Rozzah, R., Johnston, M. V. & Burd, I. 2015 In : Reproductive Sciences. 23, 6, p. 785-794 10 p.

Research output: Contribution to journalArticle

Assisted Reproductive Techniques
Superovulation
DNA Methylation
Fetal Development
Placenta

Risk factors for attention and behavioral issues in pediatric sickle cell disease

Lance, E. I., Comi, A. M., Johnston, M. V., Casella, J. F. & Shapiro, B. K. Oct 11 2015 In : Clinical Pediatrics. 54, 11, p. 1087-1093 7 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Pediatrics
Sickle Hemoglobin
Learning Disorders
Attention Deficit Disorder with Hyperactivity

Systemic dendrimer-drug treatment of ischemia-induced neonatal white matter injury

Nance, E., Porambo, M., Zhang, F., Mishra, M. K., Buelow, M., Getzenberg, R., Johnston, M., Kannan, R. M., Fatemi, A. & Kannan, S. Jul 31 2015 In : Journal of Controlled Release. 214, p. 112-120 9 p.

Research output: Contribution to journalArticle

Dendrimers
Ischemia
Wounds and Injuries
White Matter
Oligodendroglia

Systemic injection of CD34+-enriched human cord Blood cells modulates poststroke neural and glial response in a sex-dependent manner in CD1 mice

Kadam, S. D., Chen, H., Markowitz, G. J., Raja, S., George, S., Shotwell, E., Loechelt, B., Johnston, M. V., Kamani, N., Fatemi, A. & Comi, A. M. Jan 1 2015 In : Stem Cells and Development. 24, 1, p. 51-66 16 p.

Research output: Contribution to journalArticle

Fetal Blood
Neuroglia
Blood Cells
Glial Fibrillary Acidic Protein
Brain

Transplanted glial restricted precursor cells improve neurobehavioral and neuropathological outcomes in a mouse model of neonatal white matter injury despite limited cell survival

Porambo, M., Phillips, A. W., Marx, J., Ternes, K., Arauz, E., Pletnikov, M., Wilson, M. A., Rothstein, J. D., Johnston, M. V. & Fatemi, A. Mar 1 2015 In : GLIA. 63, 3, p. 452-465 14 p.

Research output: Contribution to journalArticle

Neuroglia
Cell Survival
Wounds and Injuries
White Matter
Cell Transplantation
2014

Acute onset rhythmic hiccup-like respirations secondary to oral baclofen toxicity

Srivastava, S., Hoon, A., Ogborn, J. & Johnston, M. 2014 In : Pediatric Neurology. 51, 2, p. 252-254 3 p.

Research output: Contribution to journalArticle

Hiccup
Baclofen
Respiration
GABA Receptors
Tetralogy of Fallot

A Diagnostic Approach for Cerebral Palsy in the Genomic Era

Lee, R. W., Poretti, A., Cohen, J. S., Levey, E., Gwynn, H., Johnston, M. V., Hoon, A. H. & Fatemi, A. 2014 In : NeuroMolecular Medicine. 16, 4, p. 821-844 24 p.

Research output: Contribution to journalArticle

Cerebral Palsy
Molecular Biology
Phenotype
Family Therapy
Muscle Spasticity

A novel variant in GABRB2 associated with intellectual disability and epilepsy

Srivastava, S., Cohen, J., Pevsner, J., Aradhya, S., Mcknight, D., Butler, E., Johnston, M. & Fatemi, A. Nov 1 2014 In : American Journal of Medical Genetics, Part A. 164, 11, p. 2914-2921 8 p.

Research output: Contribution to journalArticle

Intellectual Disability
gamma-Aminobutyric Acid
Epilepsy
Mutation
Amino Acids

Brain injury in canine models of cardiac surgery

Blue, M. E., Wilson, M. A., Beaty, C. A., George, T. J., Arnaoutakis, G. J., Haggerty, K. A., Jones, M., Brawn, J., Manmohan, S., Lange, M. S., Johnston, M. V., Baumgartner, W. A. & Troncoso, J. C. Dec 8 2014 In : Journal of Neuropathology and Experimental Neurology. 73, 12, p. 1134-1143 10 p.

Research output: Contribution to journalArticle

Cardiopulmonary Bypass
Brain Injuries
Thoracic Surgery
Canidae
Hippocampus

Circadian cycle-dependent EEG biomarkers of pathogenicity in adult mice following prenatal exposure to in utero inflammation

Adler, D. A., Ammanuel, S., Lei, J., Dada, T., Borbiev, T., Johnston, M. V., Kadam, S. D. & Burd, I. Sep 5 2014 In : Neuroscience. 275, p. 305-313 9 p.

Research output: Contribution to journalArticle

Virulence
Lipopolysaccharides
Electroencephalography
Biological Markers
Inflammation

Cognitive and functional impairment associated with care in the PICU

Johnston, M. V. 2014 In : Pediatric Critical Care Medicine. 15, 7, p. 676-677 2 p.

Research output: Contribution to journalArticle

Dendrimer Brain Uptake and Targeted Therapy for Brain Injury in a Large Animal Model of Hypothermic Circulatory Arrest

Mishra, M. K., Beaty, C. A., Lesniak, W. G., Kambhampati, S. P., Zhang, F., Wilson, M. A., Blue, M. E., Troncoso, J. C., Kannan, S., Johnston, M. V., Baumgartner, W. A. & Kannan, R. M. Mar 25 2014 In : ACS Nano. 8, 3, p. 2134-2147 14 p.

Research output: Contribution to journalArticle

dendrimers
Dendrimers
Brain
Animals
Anthralin

Early neurodevelopmental screening in tuberous sclerosis complex: A potential window of opportunity

Gipson, T. T., Gerner, G., Srivastava, S., Poretti, A., Vaurio, R., Hartman, A. & Johnston, M. V. 2014 In : Pediatric Neurology. 51, 3, p. 398-402 5 p.

Research output: Contribution to journalArticle

Tuberous Sclerosis
Infantile Spasms
Seizures
Language Therapy
Vigabatrin
Pediatrics
Wounds and Injuries
Heart Arrest
Drainage
Veins
Interleukin-1 Receptors
Premature Birth
Brain Injuries
Inflammation
Interleukin-1

Mouse model of intrauterine inflammation: Sex-specific differences in long-term neurologic and immune sequelae

Dada, T., Rosenzweig, J. M., Al Shammary, M., Firdaus, W., Al Rebh, S., Borbiev, T., Tekes, A., Zhang, J., Alqahtani, E., Mori, S., Pletnikov, M. V., Johnston, M. V. & Burd, I. 2014 In : Brain, Behavior, and Immunity. 38, p. 142-150 9 p.

Research output: Contribution to journalArticle

Sex Characteristics
Nervous System
Inflammation
Brain
Encephalitis
Myotonic Dystrophy
Neuroimaging
White Matter
Muscle Hypotonia
Respiratory Insufficiency

Perinatal biomarkers in prematurity: Early identification of neurologic injury

Andrikopoulou, M., Almalki, A., Farzin, A., Cordeiro, C. N., Johnston, M. V. & Burd, I. 2014 In : International Journal of Developmental Neuroscience. 36, p. 25-31 7 p.

Research output: Contribution to journalArticle

Nervous System Trauma
Biological Markers
Brain Injuries
Nervous System
Extremely Premature Infants
Mitochondrial Turnover
Sex Characteristics
Oxygen
Neurons
Glucose
Nicotinic Receptors
Encephalitis
Antibodies
Cerebrospinal Fluid
Laughter

Subthalamic nucleus involvement in children: A neuroimaging pattern-recognition approach

Bosemani, T., Anghelescu, C., Boltshauser, E., Hoon, A. H., Pearl, P. L., Craiu, D., Johnston, M. V., Huisman, T. A. G. M. & Poretti, A. 2014 In : European Journal of Paediatric Neurology. 18, 3, p. 249-256 8 p.

Research output: Contribution to journalArticle

Subthalamic Nucleus
Neuroimaging
Succinate-Semialdehyde Dehydrogenase
Leigh Disease
Kernicterus
Methyl-CpG-Binding Protein 2
Biosensing Techniques
Circadian Rhythm
Glutamic Acid
Electroencephalography
2013
Newborn Infant
Neuroimaging
Cerebellum
Periventricular Leukomalacia
Muscle Spasticity

Changing the perspective on early development of Rett syndrome

Marschik, P. B., Kaufmann, W. E., Sigafoos, J., Wolin, T., Zhang, D., Bartl-Pokorny, K. D., Pini, G., Zappella, M., Tager-Flusberg, H., Einspieler, C. & Johnston, M. V. Apr 2013 In : Research in Developmental Disabilities. 34, 4, p. 1236-1239 4 p.

Research output: Contribution to journalArticle

Rett Syndrome
Language Development

Everolimus and intensive behavioral therapy in an adolescent with tuberous sclerosis complex and severe behavior

Gipson, T. T., Jennett, H., Wachtel, L., Gregory, M., Poretti, A. & Johnston, M. V. 2013 In : Epilepsy and Behavior Case Reports. 1, 1, p. 122-125 4 p.

Research output: Contribution to journalArticle

Tuberous Sclerosis
Wounds and Injuries
Aggression
Astrocytoma
Seizures

Ischemia-induced neuroinflammation is associated with disrupted development of oligodendrocyte progenitors in a model of periventricular leukomalacia

Falahati, S., Breu, M., Waickman, A. T., Phillips, A. W., Arauz, E. J., Snyder, S., Porambo, M., Goeral, K., Comi, A. M., Wilson, M. A., Johnston, M. V. & Fatemi, A. Jul 2013 In : Developmental Neuroscience. 35, 2-3, p. 182-196 15 p.

Research output: Contribution to journalArticle

Periventricular Leukomalacia
Oligodendroglia
Stem Cells
Ischemia
Transforming Growth Factor beta1

Limbic encephalitis in a child: An atypical presentation

Mahmoud, A. A. H., Al Ghamdi, F. A. S. & Johnston, M. V. Dec 2013 In : Pediatric Neurology. 49, 6, p. 501-504 4 p.

Research output: Contribution to journalArticle

Limbic Encephalitis
Seizures
Antibodies
Memory Disorders
Short-Term Memory

Nanomedicine in cerebral palsy

Balakrishnan, B., Nance, E., Johnston, M. V., Kannan, R. & Kannan, S. Nov 1 2013 In : International Journal of Nanomedicine. 8, p. 4183-4195 13 p.

Research output: Contribution to journalArticle

Nanomedicine
Cerebral Palsy
Brain
Wounds and Injuries
Brain Injuries

Parental reports on early language and motor milestones in fragile X syndrome with and without autism spectrum disorders

Hinton, R., Budimirovic, D. B., Marschik, P. B., Talisa, V. B., Einspieler, C., Gipson, T. & Johnston, M. V. 2013 In : Developmental Neurorehabilitation. 16, 1, p. 58-66 9 p.

Research output: Contribution to journalArticle

Fragile X Syndrome
Pervasive Child Development Disorders
Age of Onset
Reproducibility of Results
Diagnostic and Statistical Manual of Mental Disorders

Pluripotent possibilities: Human umbilical cord blood cell treatment after neonatal brain injury

Verina, T., Fatemi, A., Johnston, M. V. & Comi, A. M. May 2013 In : Pediatric Neurology. 48, 5, p. 346-354 9 p.

Research output: Contribution to journalArticle

Fetal Blood
Brain Injuries
Blood Cells
Stem Cells
Transplantation

Serum biomarkers of MRI brain injury in neonatal hypoxic ischemic encephalopathy treated with whole-body hypothermia: A pilot study

Massaro, A. N., Jeromin, A., Kadom, N., Vezina, G., Hayes, R. L., Wang, K. K. W., Streeter, J. & Johnston, M. V. Mar 2013 In : Pediatric Critical Care Medicine. 14, 3, p. 310-317 8 p.

Research output: Contribution to journalArticle

Brain Hypoxia-Ischemia
Hypothermia
Brain Injuries
Biological Markers
Serum