Michael Beer

Associate Professor

School of Medicine

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fusion Physics & Astronomy

reactors Physics & Astronomy

turbulence Physics & Astronomy

tritium Physics & Astronomy

Chromatin Medicine & Life Sciences

Genome Medicine & Life Sciences

shear Physics & Astronomy

Fusion reactions Engineering & Materials Science

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Research Output 1991 2019

60 Article
2 Conference contribution

Genome-scale screens identify JNK–JUN signaling as a barrier for pluripotency exit and endoderm differentiation

Li, Q. V., Dixon, G., Verma, N., Rosen, B. P., Gordillo, M., Luo, R., Xu, C., Wang, Q., Soh, C. L., Yang, D., Crespo, M., Shukla, A., Xiang, Q., Dündar, F., Zumbo, P., Witkin, M., Koche, R., Betel, D., Chen, S., Massagué, J. & 4 others, Garippa, R., Evans, T., Beer, M. & Huangfu, D., Jun 1 2019, In : Nature genetics. 51, 6, p. 999-1010 12 p.

Research output: Contribution to journal › Article

Endoderm

Genome

Embryonic Stem Cells

Phosphotransferases

Clustered Regularly Interspaced Short Palindromic Repeats

Integration of multiple epigenomic marks improves prediction of variant impact in saturation mutagenesis reporter assay

Shigaki, D., Adato, O., Adhikari, A. N., Dong, S., Hawkins-Hooker, A., Inoue, F., Juven-Gershon, T., Kenlay, H., Martin, B., Patra, A., Penzar, D. D., Schubach, M., Xiong, C., Yan, Z., Boyle, A. P., Kreimer, A., Kulakovskiy, I. V., Reid, J., Unger, R., Yosef, N. & 4 others, Shendure, J., Ahituv, N., Kircher, M. & Beer, M., Sep 1 2019, In : Human mutation. 40, 9, p. 1280-1291 12 p.

Research output: Contribution to journal › Article

Epigenomics

Mutagenesis

Base Pairing

Libraries

Chromatin

Genetic determinants of co-accessible chromatin regions in activated T cells across humans

Gate, R. E., Cheng, C. S., Aiden, A. P., Siba, A., Tabaka, M., Lituiev, D., Machol, I., Gordon, M. G., Subramaniam, M., Shamim, M., Hougen, K. L., Wortman, I., Huang, S. C., Durand, N. C., Feng, T., de Jager, P. L., Chang, H. Y., Aiden, E. L., Benoist, C., Beer, M. & 2 others, Ye, C. J. & Regev, A., Jul 9 2018, (Accepted/In press) In : Nature Genetics. p. 1-11 11 p.

Research output: Contribution to journal › Article

Chromatin

T-Lymphocytes

Gene Expression

Autoimmune Diseases

RNA

Local epigenomic state cannot discriminate interacting and non-interacting enhancer–promoter pairs with high accuracy

Xi, W. & Beer, M., Dec 1 2018, In : PLoS Computational Biology. 14, 12, e1006625.

Research output: Contribution to journal › Article

Promoter

Epigenomics

epigenetics

Design of experiments

Learning systems

Parkinson-Associated SNCA Enhancer Variants Revealed by Open Chromatin in Mouse Dopamine Neurons

McClymont, S. A., Hook, P. W., Soto, A. I., Reed, X., Law, W. D., Kerans, S. J., Waite, E. L., Briceno, N. J., Thole, J. F., Heckman, M. G., Diehl, N. N., Wszolek, Z. K., Moore, C. D., Zhu, H., Akiyama, J. A., Dickel, D. E., Visel, A., Pennacchio, L. A., Ross, O. A., Beer, M. & 1 others, McCallion, A. S., Dec 6 2018, In : American Journal of Human Genetics. 103, 6, p. 874-892 19 p.

Research output: Contribution to journal › Article

Dopaminergic Neurons

Chromatin

Parkinson Disease

Mesencephalon

Zebrafish