Mengnan Tian

Research Associate

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Fingerprint Dive into the research topics where Mengnan Tian is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Myoclonic Epilepsy Medicine & Life Sciences
Nonsense Codon Medicine & Life Sciences
GABA-A Receptors Medicine & Life Sciences
Nonsense Mediated mRNA Decay Medicine & Life Sciences
Terminator Codon Medicine & Life Sciences
Bacterial Artificial Chromosomes Medicine & Life Sciences
Epilepsy Medicine & Life Sciences
Mutation Medicine & Life Sciences

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Research Output 2012 2017

Overexpressing wild-type γ2 subunits rescued the seizure phenotype in Gabrg2+/Q390X Dravet syndrome mice

Huang, X., Zhou, C., Tian, M., Kang, J. Q., Shen, W., Verdier, K., Pimenta, A. & MacDonald, R. L., Aug 1 2017, In : Epilepsia. 58, 8, p. 1451-1461 11 p.

Research output: Contribution to journalArticle

Open Access
Myoclonic Epilepsy

Impaired surface αβγ GABAA receptor expression in familial epilepsy due to a GABRG2 frameshift mutation

Tian, M., Mei, D., Freri, E., Hernandez, C. C., Granata, T., Shen, W., Macdonald, R. L. & Guerrini, R., Feb 1 2013, In : Neurobiology of Disease. 50, 1, p. 135-141 7 p.

Research output: Contribution to journalArticle

Frameshift Mutation
GABA-A Receptors
Terminator Codon

The GABRG2 nonsense mutation, Q40X, associated with Dravet syndrome activated NMD and generated a truncated subunit that was partially rescued by aminoglycoside-induced stop codon read-through

Huang, X., Tian, M., Hernandez, C. C., Hu, N. & MacDonald, R. L., Oct 1 2012, In : Neurobiology of Disease. 48, 1, p. 115-123 9 p.

Research output: Contribution to journalArticle

Nonsense Mediated mRNA Decay
Myoclonic Epilepsy
Terminator Codon
Nonsense Codon
Open Access
Bacterial Artificial Chromosomes
Absence Epilepsy
Nonsense Codon
RNA Splice Sites