Melissa Higdon

Research Associate

20152019
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Research Output 2015 2019

2019

Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study

O'Brien, K. L., Baggett, H. C., Brooks, W. A., Feikin, D. R., Hammitt, L. L., Higdon, M. M., Howie, S. R. C., Deloria Knoll, M., Kotloff, K. L., Levine, O. S., Madhi, S. A., Murdoch, D. R., Prosperi, C., Scott, J. A. G., Shi, Q., Thea, D. M., Wu, Z., Zeger, S. L., Adrian, P. V., Akarasewi, P. & 57 others, Anderson, T. P., Antonio, M., Awori, J. O., Baillie, V. L., Bunthi, C., Chipeta, J., Chisti, M. J., Crawley, J., DeLuca, A. N., Driscoll, A. J., Ebruke, B. E., Endtz, H. P., Fancourt, N., Fu, W., Goswami, D., Groome, M. J., Haddix, M., Hossain, L., Jahan, Y., Kagucia, E. W., Kamau, A., Karron, R. A., Kazungu, S., Kourouma, N., Kuwanda, L., Kwenda, G., Li, M., Machuka, E. M., Mackenzie, G., Mahomed, N., Maloney, S. A., McLellan, J. L., Mitchell, J. L., Moore, D. P., Morpeth, S. C., Mudau, A., Mwananyanda, L., Mwansa, J., Silaba Ominde, M., Onwuchekwa, U., Park, D. E., Rhodes, J., Sawatwong, P., Seidenberg, P., Shamsul, A., Simões, E. A. F., Sissoko, S., Wa Somwe, S., Sow, S. O., Sylla, M., Tamboura, B., Tapia, M. D., Thamthitiwat, S., Toure, A., Watson, N. L., Zaman, K. & Zaman, S. M. A., Aug 31 2019, In : The Lancet. 394, 10200, p. 757-779 23 p.

Research output: Contribution to journalArticle

Open Access
HIV Infections
Case-Control Studies
Pneumonia
Paramyxoviridae Infections
Respiratory Syncytial Viruses
2017
Respiratory Syncytial Viruses
C-Reactive Protein
Pneumonia
Bacterial Pneumonia
Research

Chest radiograph findings in childhood pneumonia cases from the multisite PERCH study

PERCH Study Group, Jan 1 2017, In : Clinical Infectious Diseases. 64, p. S262-S270

Research output: Contribution to journalArticle

Pneumonia
Thorax
Gambia
Mali
Zambia
Moraxella (Branhamella) catarrhalis
Pneumocystis carinii
Haemophilus influenzae
Respiratory System
Staphylococcus aureus

Data management and data quality in PERCH, a large international case-control study of severe childhood pneumonia

Watson, N. L., Prosperi, C., Driscoll, A. J., Higdon, M., Park, D. E., Sanza, M., Deluca, A., Awori, J. O., Goswami, D., Hammond, E., Hossain, L., Johnson, C., Kamau, A., Kuwanda, L., Moore, D. P., Neyzari, O., Onwuchekwa, U., Parker, D., Sapchookul, P., Seidenberg, P. & 9 others, Shamsul, A., Siazeele, K., Srisaengchai, P., Sylla, M., Levine, O. S., Murdoch, D. R., O'Brien, K. L., Wolff, M. & Knoll, M. D., Jan 1 2017, In : Clinical Infectious Diseases. 64, p. S238-S244

Research output: Contribution to journalArticle

Case-Control Studies
Pneumonia
Research
Information Systems
Internet
Pneumococcal Pneumonia
Streptococcus pneumoniae
Pneumonia
Research
Child Health
Pneumococcal Pneumonia
Polymerase Chain Reaction
DNA
Pneumonia
Research
Pneumococcal Pneumonia
Pneumonia
Polymerase Chain Reaction
Research
Streptococcus pneumoniae

Is higher viral load in the upper respiratory tract associated with severe pneumonia? Findings from the PERCH study

PERCH Study Group, Jan 1 2017, In : Clinical Infectious Diseases. 64, p. S337-S346

Research output: Contribution to journalArticle

Viral Load
Respiratory System
Pneumonia
Viruses
Viral Pneumonia
Sputum
Pneumonia
Polymerase Chain Reaction
Research
Child Health

Microscopic analysis and quality assessment of induced sputum from children with pneumonia in the PERCH study

PERCH Study Group, Jan 1 2017, In : Clinical Infectious Diseases. 64, p. S271-S279

Research output: Contribution to journalArticle

Sputum
Pneumonia
Respiratory System
Epithelial Cells
Hospitalized Child

Safety of induced sputum collection in children hospitalized with severe or very severe pneumonia

PERCH Study Group, Jan 1 2017, In : Clinical Infectious Diseases. 64, p. S301-S308

Research output: Contribution to journalArticle

Hospitalized Child
Sputum
Pneumonia
Safety
Oxygen
Case-Control Studies
Pneumonia
Research
Selection Bias
Research Personnel

Standardization of clinical assessment and sample collection across all PERCH study sites

PERCH Study Groupa, Jan 1 2017, In : Clinical Infectious Diseases. 64, p. S228-S237

Research output: Contribution to journalArticle

Pneumonia
Specimen Handling
Research
Checklist
Gambia

The diagnostic utility of induced sputum microscopy and culture in childhood pneumonia

PERCH Study Group, Jan 1 2017, In : Clinical Infectious Diseases. 64, p. S280-S288

Research output: Contribution to journalArticle

Sputum
Microscopy
Pneumonia
Hospitalized Child
Research

The effect of antibiotic exposure and specimen volume on the detection of bacterial pathogens in children with pneumonia

PERCH Study Group, Jan 1 2017, In : Clinical Infectious Diseases. 64, p. S368-S377

Research output: Contribution to journalArticle

Pneumonia
Anti-Bacterial Agents
Sputum
Polymerase Chain Reaction
Streptococcus pneumoniae

The incremental value of repeated induced sputum and gastric aspirate samples for the diagnosis of pulmonary tuberculosis in young children with acute community- acquired pneumonia

Moore, D. P., Higdon, M., Hammitt, L. L., Prosperi, C., Deluca, A., Da Silva, P., Baillie, V. L., Adrian, P. V., Mudau, A., Knoll, M. D., Feikin, D., Murdoch, D. R., O'Brien, K. L. & Madhi, S. A., Jan 1 2017, In : Clinical Infectious Diseases. 64, p. S309-S316

Research output: Contribution to journalArticle

Sputum
Pulmonary Tuberculosis
Pneumonia
Stomach
Mycobacterium tuberculosis
2016

Pertussis-associated pneumonia in infants and children from low-and middle-income countries participating in the perch study

Barger-Kamate, B., Knoll, M. D., Kagucia, E. W., Prosperi, C., Baggett, H. C., Brooks, W. A., Feikin, D., Hammitt, L. L., Howie, S. R. C., Levine, O. S., Madhi, S. A., Scott, J. A. G., Thea, D. M., Amornintapichet, T., Anderson, T. P., Awori, J. O., Baillie, V. L., Chipeta, J., Deluca, A., Driscoll, A. J. & 16 others, Goswami, D., Higdon, M., Hossain, L., Karron, R. A., Maloney, S., Moore, D. P., Morpeth, S. C., Mwananyanda, L., Ofordile, O., Olutunde, E., Park, D. E., Sow, S. O., Tapia, M. D., Murdoch, D. R., O'Brien, K. L. & Kotloff, K. L., Dec 1 2016, In : Clinical Infectious Diseases. 63, p. S187-S196

Research output: Contribution to journalArticle

Perches
Whooping Cough
Pneumonia
Odds Ratio
Bordetella pertussis
2015

Arsenic exposure is associated with pediatric pneumonia in rural Bangladesh: A case control study

George, C. M., Brooks, W. A., Graziano, J. H., Nonyane, B. A. S., Hossain, L., Goswami, D., Zaman, K., Yunus, M., Khan, A. F., Jahan, Y., Ahmed, D., Slavkovich, V., Higdon, M., Knoll, M. D. & O'Brien, K. L., Oct 23 2015, In : Environmental Health: A Global Access Science Source. 14, 1, 83.

Research output: Contribution to journalArticle

Bangladesh
Arsenic
Case-Control Studies
Pneumonia
Pediatrics

Contribution of the BacT/Alert MB Mycobacterium bottle to bloodstream infection surveillance in Thailand: Added yield for Burkholderia pseudomallei

Jorakate, P., Higdon, M., Kaewpan, A., Makprasert, S., Yuenprakhon, S., Tawisaid, K., Dejsirilert, S., Whistler, T. & Baggetta, H. C., Mar 1 2015, In : Journal of Clinical Microbiology. 53, 3, p. 910-914 5 p.

Research output: Contribution to journalArticle

Burkholderia pseudomallei
Thailand
Mycobacterium
Infection
Community-Acquired Infections