Melina Jones

Research Associate

19982018
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Research Output 1998 2018

2018
Neuromyelitis Optica
Autoimmune Experimental Encephalomyelitis
Aquaporin 4
Pathology
Neutrophils
2015

Minimally-invasive technique for injection into rat optic nerve

Raykova, K., Jones, M., Huang, H., Hoffman, P. F. & Levy, M., May 19 2015, In : Journal of Visualized Experiments. 2015, 99, e52249.

Research output: Contribution to journalArticle

Optic Nerve
Rats
Optics
Injections
Direct injection

Pathogenic aquaporin-4 reactive T cells are sufficient to induce mouse model of neuromyelitis optica

Jones, M., Huang, H., Calabresi, P. & Levy, M., May 21 2015, In : Acta neuropathologica communications. 3, p. 28 1 p.

Research output: Contribution to journalArticle

Aquaporin 4
Neuromyelitis Optica
T-Lymphocytes
Antibodies
Optic Nerve
2014

Evidence for classic complement activity in neuromyelitis optica

Jones, M., Fox-Talbot, K. & Levy, M., 2014, In : Clinical Neuropathology. 33, 3, p. 251-252 2 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Classical Complement Pathway
Complement C4
Spinal Cord
2013

Accelerated axon loss in MOG35-55 experimental autoimmune encephalomyelitis (EAE) in myelin-associated glycoprotein-deficient (MAGKO) mice

Jones, M., Nguyen, T. T., Ewaleifoh, O., Lebson, L., Whartenby, K., Griffin, J. W. & Calabresi, P., 2013, In : Journal of Neuroimmunology. 262, 1-2, p. 53-61 9 p.

Research output: Contribution to journalArticle

Myelin-Associated Glycoprotein
Autoimmune Experimental Encephalomyelitis
Axons
Oligodendroglia
Immunization

Passively transferred human NMO-IgG exacerbates demyelination in mouse experimental autoimmune encephalomyelitis

Saini, H., Rifkin, R., Gorelik, M., Huang, H., Ferguson, Z., Jones, M. & Levy, M., Aug 8 2013, In : BMC Neurology. 13, p. 1-9 9 p., 104.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Autoimmune Experimental Encephalomyelitis
Demyelinating Diseases
Immunoglobulin G
Aquaporin 4
2012
Cuprizone
Diffusion Tensor Imaging
Corpus Callosum
Anisotropy
Demyelinating Diseases

Probing mouse brain microstructure using oscillating gradient diffusion MRI

Aggarwal, M., Jones, M., Calabresi, P., Mori, S. & Zhang, J., Jan 2012, In : Magnetic Resonance in Medicine. 67, 1, p. 98-109 12 p.

Research output: Contribution to journalArticle

Diffusion Magnetic Resonance Imaging
Cuprizone
Brain
Corpus Callosum
Staining and Labeling

Review of animal models of neuromyelitis optica

Jones, M., Collongues, N., De Seze, J., Kinoshita, M., Nakatsuji, Y. & Levy, M., Oct 2012, In : Multiple Sclerosis and Related Disorders. 1, 4, p. 174-179 6 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Animal Models
Aquaporin 4
Immunoglobulin G
Optic Nerve Diseases
2011

Three-Dimensional imaging of the mouse neurovasculature with magnetic resonance microscopy

Pathak, A., Kim, E., Zhang, J. & Jones, M., 2011, In : PLoS One. 6, 7, e22643.

Research output: Contribution to journalArticle

Three-Dimensional Imaging
Magnetic resonance
Blood Vessels
Microscopy
microscopy
2010

FLT-3 expression and function on microglia in multiple sclerosis

DeBoy, C. A., Rus, H., Tegla, C., Cudrici, C., Jones, M., Pardo-Villamizar, C. A., Small, D., Whartenby, K. & Calabresi, P., Oct 2010, In : Experimental and Molecular Pathology. 89, 2, p. 109-116 8 p.

Research output: Contribution to journalArticle

Microglia
Multiple Sclerosis
Brain
Dendritic Cells
Neurology

q-space and conventional diffusion imaging of axon and myelin damage in the rat spinal cord after axotomy

Farrell, J. A. D., Zhang, J., Jones, M., DeBoy, C. A., Hoffman, P. N., Landman, B. A., Smith, S. A., Reich, D. S., Calabresi, P. & Van Zijl, P. C., May 2010, In : Magnetic Resonance in Medicine. 63, 5, p. 1323-1335 13 p.

Research output: Contribution to journalArticle

Axotomy
Myelin Sheath
Axons
Spinal Cord
Histology
2009

Axonal protective effects of the myelin-associated glycoprotein

Nguyen, T., Mehta, N. R., Conant, K., Kim, K. J., Jones, M., Calabresi, P., Melli, G., Hoke, A., Schnaar, R. L., Ming, G. L., Song, H., Keswani, S. C. & Griffin, J. W., Jan 21 2009, In : Journal of Neuroscience. 29, 3, p. 630-637 8 p.

Research output: Contribution to journalArticle

Myelin-Associated Glycoprotein
Axons
Neurofilament Proteins
Charcot-Marie-Tooth Disease
Demyelinating Diseases

Diffusion tensor magnetic resonance imaging of wallerian degeneration in rat spinal cord after dorsal root axotomy

Zhang, J., Jones, M., Deboy, C. A., Reich, D. S., Farrell, J. A. D., Hoffman, P. N., Griffin, J. W., Sheikh, K. A., Miller, M. I., Mori, S. & Calabresi, P., Mar 11 2009, In : Journal of Neuroscience. 29, 10, p. 3160-3171 12 p.

Research output: Contribution to journalArticle

Wallerian Degeneration
Axotomy
Diffusion Magnetic Resonance Imaging
Spinal Nerve Roots
Axons
2008

Behavioral and pathological outcomes in MOG 35-55 experimental autoimmune encephalomyelitis

Jones, M., Nguyen, T. T., DeBoy, C. A., Griffin, J. W., Whartenby, K., Kerr, D. A. & Calabresi, P., Aug 13 2008, In : Journal of Neuroimmunology. 199, 1-2, p. 83-93 11 p.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Axons
Myelin-Oligodendrocyte Glycoprotein
Hand Strength
Multiple Sclerosis

Interleukin-17 in transverse myelitis and multiple sclerosis

Graber, J. J., Allie, S. R., Mullen, K. M., Jones, M., Wang, T., Krishnan, C., Kaplin, A. I., Nath, A., Kerr, D. A. & Calabresi, P., May 30 2008, In : Journal of Neuroimmunology. 196, 1-2, p. 124-132 9 p.

Research output: Contribution to journalArticle

Transverse Myelitis
Interleukin-17
Multiple Sclerosis
Interleukin-6
Nervous System Diseases
2007

Agar-gelatin for embedding tissues prior to paraffin processing

Jones, M. & Calabresi, P., May 2007, In : BioTechniques. 42, 5, p. 569-570 2 p.

Research output: Contribution to journalArticle

Tissue Embedding
Paraffin Embedding
Gelatin
Paraffin
Agar

High resolution diffusion tensor imaging of axonal damage in focal inflammatory and demyelinating lesions in rat spinal cord

DeBoy, C. A., Zhang, J., Dike, S., Shats, I., Jones, M., Reich, D. S., Mori, S., Nguyen, T., Rothstein, B., Miller, R. H., Griffin, J. T., Kerr, D. A. & Calabresi, P., Aug 2007, In : Brain. 130, 8, p. 2199-2210 12 p.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Spinal Cord
Multiple Sclerosis
Axons
Staining and Labeling
2006

Cleavage of cystatin C in the cerebrospinal fluid of patients with multiple sclerosis

Irani, D. N., Anderson, C., Gundry, R., Cotter, R. J., Moore, S., Kerr, D. A., McArthur, J. C., Sacktor, N., Pardo-Villamizar, C. A., Jones, M., Calabresi, P. & Nath, A., Feb 2006, In : Annals of Neurology. 59, 2, p. 237-247 11 p.

Research output: Contribution to journalArticle

Cystatin C
Multiple Sclerosis
Cerebrospinal Fluid
Transverse Myelitis
Virus Diseases

Granzyme B mediates neurotoxicity through a G-protein-coupled receptor

Wang, T., Allie, R., Conant, K., Haughey, N., Turchan-Chelowo, J., Hahn, K., Rosen, A., Steiner, J., Keswani, S., Jones, M., Calabresi, P. & Nath, A., Jun 2006, In : FASEB Journal. 20, 8

Research output: Contribution to journalArticle

Granzymes
neurotoxicity
G-Protein-Coupled Receptors
T-cells
T-lymphocytes
2003

Autoantibodies to amyloid β-peptide (Aβ) are increased in Alzheimer's disease patients and Aβ antibodies can enhance Aβ neurotoxicity: Implications for disease pathogenesis and vaccine development

Nath, A., Hall, E., Tuzova, M., Dobbs, M., Jones, M., Anderson, C., Woodward, J., Guo, Z., Fu, W., Kryscio, R., Wekstein, D., Smith, C., Markesbery, W. R. & Mattson, M. P., 2003, In : NeuroMolecular Medicine. 3, 1, p. 29-39 11 p.

Research output: Contribution to journalArticle

Amyloid
Autoantibodies
Alzheimer Disease
Vaccines
Antibodies

Neuronal injury in hippocampus with human immunodeficiency virus transactivating protein, Tat

Maragos, W. F., Tillman, P., Jones, M., Bruce-Keller, A. J., Roth, S., Bell, J. E. & Nath, A., Mar 17 2003, In : Neuroscience. 117, 1, p. 43-53 11 p.

Research output: Contribution to journalArticle

Human Immunodeficiency Virus Proteins
Hippocampus
HIV
Wounds and Injuries
Encephalitis
2000

Detection of the human immunodeficiency virus regulatory protein tat in CNS tissues

Hudson, L., Liu, J., Nath, A., Jones, M., Raghavan, R., Narayan, O., Male, D. & Everall, I., 2000, In : Journal of NeuroVirology. 6, 2, p. 145-155 11 p.

Research output: Contribution to journalArticle

Human Immunodeficiency Virus Proteins
Encephalitis
HIV
tat Gene Products
Simian Immunodeficiency Virus

Immunolocalization of HIV envelope gp120 in HIV encephalitis with dementia

Jones, M., Bell, J. E. & Nath, A., 2000, In : AIDS. 14, 17, p. 2709-2713 5 p.

Research output: Contribution to journalArticle

HIV Envelope Protein gp120
AIDS Dementia Complex
Neurotoxins
Microglia
Encephalitis

Neurotoxicity and dysfunction of dopaminergic systems associated with AIDS dementia

Nath, A., Anderson, C., Jones, M., Maragos, W., Booze, R., Mactutus, C., Bell, J., Hauser, K. & Mattson, M., 2000, In : Journal of Psychopharmacology. 14, 3, p. 222-227 6 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Dementia
Acquired Immunodeficiency Syndrome
Viruses
Dopamine

Synergistic neurotoxicity by human immunodeficiency virus proteins Tat and gp120: Protection by memantine

Nath, A., Haughey, N., Jones, M., Anderson, C., Bell, J. E. & Geiger, J. D., 2000, In : Annals of Neurology. 47, 2, p. 186-194 9 p.

Research output: Contribution to journalArticle

Memantine
Human Immunodeficiency Virus Proteins
HIV-1
Encephalitis
Cell Death

Uptake of HIV-1 Tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands

Liu, Y., Jones, M., Hingtgen, C. M., Bu, G., Laribee, N., Tanzi, R. E., Moir, R. D., Nath, A. & He, J. J., 2000, In : Nature Medicine. 6, 12, p. 1380-1387 8 p.

Research output: Contribution to journalArticle

LDL-Receptor Related Proteins
Trans-Activators
LDL Receptors
Viruses
Lipoprotein Receptors
1999

Evidence that Par-4 participates in the pathogenesis of HIV encephalitis

Kruman, I. I., Nath, A., Maragos, W. F., Chan, S. L., Jones, M., Rangnekar, V. M., Jakel, R. J. & Mattson, M. P., Jul 1999, In : American Journal of Pathology. 155, 1, p. 39-46 8 p.

Research output: Contribution to journalArticle

Encephalitis
HIV-1
HIV
Apoptosis
Neurons
1998

Intraventricular injection of human immunodeficiency virus type 1 (HIV- 1) Tat protein causes inflammation, gliosis, apoptosis, and ventricular enlargement

Jones, M., Olafson, K., Del Bigio, M. R., Peeling, J. & Nath, A., Jun 1998, In : Journal of Neuropathology and Experimental Neurology. 57, 6, p. 563-570 8 p.

Research output: Contribution to journalArticle

tat Gene Products
Intraventricular Injections
Gliosis
HIV-1
Human Immunodeficiency Virus tat Gene Products