Meifang Xiao

Research Associate

20042020

Research output per year

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Research Output

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Article
2004

Establishment of liver specific glucokinase gene knockout mice: A new animal model for screening anti-diabetic drugs

Zhang, Y. L., Tan, X. H., Xiao, M. F., Li, H., Mao, Y. Q., Yang, X. & Tan, H. R., Dec 2004, In : Acta Pharmacologica Sinica. 25, 12, p. 1659-1665 7 p.

Research output: Contribution to journalArticle

2005

Mechanisms of oleic acid deterioration in insulin secretion: Role in the pathogenesis of type 2 diabetes

Zhang, Y., Xiao, M., Niu, G. & Tan, H., Sep 9 2005, In : Life Sciences. 77, 17, p. 2071-2081 11 p.

Research output: Contribution to journalArticle

2009

Neural cell adhesion molecule modulates dopaminergic signaling and behavior by regulating dopamine D2 receptor internalization

Xiao, M. F., Xu, J. C., Tereshchenko, Y., Novak, D., Schachner, M. & Kleene, R., Nov 25 2009, In : Journal of Neuroscience. 29, 47, p. 14752-14763 12 p.

Research output: Contribution to journalArticle

Resistin and insulin resistance in hepatocytes: Resistin disturbs glycogen metabolism at the protein level

Yang, Y., Xiao, M., Mao, Y., Li, H., Zhao, S., Gu, Y., Wang, R., Yu, J., Zhang, X., Irwin, D. M., Niu, G. & Tan, H., Jun 2009, In : Biomedicine and Pharmacotherapy. 63, 5, p. 366-374 9 p.

Research output: Contribution to journalArticle

2010

Binding of the receptor tyrosine kinase TrkB to the Neural Cell Adhesion Molecule (NCAM) regulates phosphorylation of NCAM and NCAM-dependent neurite outgrowth

Cassens, C., Kleene, R., Xiao, M. F., Friedrich, C., Dityateva, G., Schafer-Nielsen, C. & Schachner, M., Sep 10 2010, In : Journal of Biological Chemistry. 285, 37, p. 28959-28967 9 p.

Research output: Contribution to journalArticle

Functional consequences of the interactions among the Neural Cell Adhesion Molecule NCAM, the receptor tyrosine kinase TrkB, and the inwardly rectifying K+ channel KIR3.3

Kleene, R., Cassens, C., Bähring, R., Theis, T., Xiao, M. F., Dityatev, A., Schafer-Nielsen, C., Döring, F., Wischmeyer, E. & Schachner, M., Sep 10 2010, In : Journal of Biological Chemistry. 285, 37, p. 28968-28979 12 p.

Research output: Contribution to journalArticle

NCAM-induced neurite outgrowth depends on binding of calmodulin to NCAM and on nuclear import of NCAM and fak fragments

Kleene, R., Mzoughi, M., Joshi, G., Kalus, I., Bormann, U., Schulze, C., Xiao, M. F., Dityatev, A. & Schachner, M., Aug 11 2010, In : Journal of Neuroscience. 30, 32, p. 10784-10798 15 p.

Research output: Contribution to journalArticle

Neural cell adhesion molecule-associated polysialic acid regulates synaptic plasticity and learning by restraining the signaling through GluN2B-containing NMDA receptors

Kochlamazashvili, G., Senkov, O., Grebenyuk, S., Robinson, C., Xiao, M. F., Stummeyer, K., Gerardy-Schahn, R., Engel, A. K., Feig, L., Semyanov, A., Suppiramaniam, V., Schachner, M. & Dityatev, A., Mar 17 2010, In : Journal of Neuroscience. 30, 11, p. 4171-4183 13 p.

Research output: Contribution to journalArticle

Polysialic acid glycomimetic promotes functional recovery and plasticity after spinal cord injury in mice

Mehanna, A., Jakovcevski, I., Acar, A., Xiao, M., Loers, G., Rougon, G., Irintchev, A. & Schachner, M., Jan 2010, In : Molecular Therapy. 18, 1, p. 34-43 10 p.

Research output: Contribution to journalArticle

2011

Adhesion molecule L1 overexpressed under the control of the neuronal Thy-1 promoter improves myelination after peripheral nerve injury in adult mice

Guseva, D., Zerwas, M., Xiao, M. F., Jakovcevski, I., Irintchev, A. & Schachner, M., Jun 1 2011, In : Experimental Neurology. 229, 2, p. 339-352 14 p.

Research output: Contribution to journalArticle

Transplanted L1 expressing radial glia and astrocytes enhance recovery after spinal cord injury

Xu, J. C., Bernreuther, C., Cui, Y. F., Jakovcevski, I., Hargus, G., Xiao, M. F. & Schachner, M., Sep 1 2011, In : Journal of neurotrauma. 28, 9, p. 1921-1937 17 p.

Research output: Contribution to journalArticle

2014

The extracellular matrix glycoprotein tenascin-R regulates neurogenesis during development and in the adult dentate gyrus of mice

Xu, J. C., Xiao, M. F., Jakovcevski, I., Sivukhina, E., Hargus, G., Cui, Y. F., Irintchev, A., Schachner, M. & Bernreuther, C., Feb 1 2014, In : Journal of cell science. 127, 3, p. 641-652 12 p.

Research output: Contribution to journalArticle

2015

Definition of a Bidirectional Activity-Dependent Pathway Involving BDNF and Narp

Mariga, A., Glaser, J., Mathias, L., Xu, D., Xiao, M., Worley, P., Ninan, I. & Chao, M. V., Dec 1 2015, In : Cell Reports. 13, 9, p. 1747-1756 10 p.

Research output: Contribution to journalArticle

Structural basis of arc binding to synaptic proteins: Implications for cognitive disease

Zhang, W., Wu, J., Ward, M. D., Yang, S., Chuang, Y. A., Xiao, M., Li, R., Leahy, D. J. & Worley, P. F., Apr 22 2015, In : Neuron. 86, 2, p. 490-500 11 p.

Research output: Contribution to journalArticle

2019

Synaptic biomarkers in CSF aid in diagnosis, correlate with cognition and predict progression in MCI and Alzheimer's disease

Alzheimer's Disease Neuroimaging Initiative (ADNI), 2019, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 5, p. 871-882 12 p.

Research output: Contribution to journalArticle

Open Access
2020

A non-mosaic transchromosomic mouse model of down syndrome carrying the long arm of human chromosome 21

Kazuki, Y., Gao, F. J., Li, Y., Moyer, A. J., Devenney, B., Hiramatsu, K., Miyagawa-Tomita, S., Abe, S., Kazuki, K., Kajitani, N., Uno, N., Takehara, S., Takiguchi, M., Yamakawa, M., Hasegawa, A., Shimizu, R., Matsukura, S., Noda, N., Ogonuki, N., Inoue, K. & 14 others, Matoba, S., Ogura, A., Florea, L. D., Savonenko, A., Xiao, M., Wu, D., Batista, D. A. S., Yang, J., Qiu, Z., Singh, N., Richtsmeier, J. T., Takeuchi, T., Oshimura, M. & Reeves, R. H., Jun 2020, In : eLife. 9, p. 1-29 29 p., e56223.

Research output: Contribution to journalArticle

Open Access

Cerebrospinal fluid profile of NPTX2 supports role of Alzheimer's disease-related inhibitory circuit dysfunction in adults with down syndrome

Belbin, O., Xiao, M. F., Xu, D., Carmona-Iragui, M., Pegueroles, J., Benejam, B., Videla, L., Fernández, S., Barroeta, I., Nuñez-Llaves, R., Montal, V., Vilaplana, E., Altuna, M., Clarimón, J., Alcolea, D., Blesa, R., Lleó, A., Worley, P. F. & Fortea, J., Aug 17 2020, In : Molecular neurodegeneration. 15, 1, p. 1-10 10 p., 46.

Research output: Contribution to journalArticle

Open Access

Identification of novel cerebrospinal fluid biomarker candidates for dementia with Lewy bodies: a proteomic approach

Van Steenoven, I., Koel-Simmelink, M. J. A., Vergouw, L. J. M., Tijms, B. M., Piersma, S. R., Pham, T. V., Bridel, C., Ferri, G. L., Cocco, C., Noli, B., Worley, P. F., Worley, P. F., Xiao, M. F., Xu, D., Oeckl, P., Otto, M., Van Der Flier, W. M., Van Der Flier, W. M., De Jong, F. J., Jimenez, C. R. & 2 others, Lemstra, A. W. & Teunissen, C. E., Jun 18 2020, In : Molecular neurodegeneration. 15, 1, 36.

Research output: Contribution to journalArticle

Open Access

Neuronal pentraxin 2: A synapse-derived CSF biomarker in genetic frontotemporal dementia

Van Der Ende, E. L., Xiao, M., Xu, D., Poos, J. M., Panman, J. L., Panman, J. L., Jiskoot, L. C., Jiskoot, L. C., Meeter, L. H., Dopper, E. G. P., Papma, J. M., Heller, C., Convery, R., Moore, K., Bocchetta, M., Neason, M., Peakman, G., Cash, D. M., Teunissen, C. E., Graff, C. & 32 others, Graff, C., Synofzik, M., Synofzik, M., Moreno, F., Finger, E., Sánchez-Valle, R., Vandenberghe, R., Laforce, R., Masellis, M., Tartaglia, M. C., Rowe, J. B., Butler, C. R., Ducharme, S., Gerhard, A., Gerhard, A., Danek, A., Levin, J., Levin, J., Levin, J., Pijnenburg, Y. A. L., Otto, M., Borroni, B., Tagliavini, F., De Mendonca, A., Santana, I., Galimberti, D., Galimberti, D., Seelaar, H., Rohrer, J. D., Worley, P. F., Worley, P. F. & Van Swieten, J. C., Jun 1 2020, In : Journal of Neurology, Neurosurgery and Psychiatry. 91, 6, p. 612-621 10 p.

Research output: Contribution to journalArticle

Open Access