Research Output 1988 2017

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2017

Generation-6 hydroxyl PAMAM dendrimers improve CNS penetration from intravenous administration in a large animal brain injury model

Zhang, F., Trent Magruder, J., Lin, Y. A., Crawford, T. C., Grimm, J. C., Sciortino, C. M., Wilson, M. A., Blue, M. E., Kannan, S., Johnston, M. V., Baumgartner, W. A. & Kannan, R. M. Mar 10 2017 In : Journal of Controlled Release. 249, p. 173-182 10 p.

Research output: Research - peer-reviewArticle

Dendrimers
Intravenous Administration
Hydroxyl Radical
Brain Injuries
Poly(amidoamine)
2016

Glial-Restricted Precursors Protect Neonatal Brain Slices from Hypoxic-Ischemic Cell Death Without Direct Tissue Contact

Sweda, R., Phillips, A. W., Marx, J., Johnston, M. V., Wilson, M. A. & Fatemi, A. Jul 1 2016 In : Stem Cells and Development. 25, 13, p. 975-985 11 p.

Research output: Research - peer-reviewArticle

Neuroglia
Cell Death
Brain
Stem Cells
Ischemia
Dendrimers
Nanotechnology
Brain Injuries
Canidae
Inflammation
2015

Transplanted glial restricted precursor cells improve neurobehavioral and neuropathological outcomes in a mouse model of neonatal white matter injury despite limited cell survival

Porambo, M., Phillips, A. W., Marx, J., Ternes, K., Arauz, E., Pletnikov, M., Wilson, M. A., Rothstein, J. D., Johnston, M. V. & Fatemi, A. Mar 1 2015 In : GLIA. 63, 3, p. 452-465 14 p.

Research output: Research - peer-reviewArticle

Neuroglia
Cell Survival
Wounds and Injuries
White Matter
Cell Transplantation
2014

Brain injury in canine models of cardiac surgery

Blue, M. E., Wilson, M. A., Beaty, C. A., George, T. J., Arnaoutakis, G. J., Haggerty, K. A., Jones, M., Brawn, J., Manmohan, S., Lange, M. S., Johnston, M. V., Baumgartner, W. A. & Troncoso, J. C. Dec 8 2014 In : Journal of Neuropathology and Experimental Neurology. 73, 12, p. 1134-1143 10 p.

Research output: Research - peer-reviewArticle

Cardiopulmonary Bypass
Brain Injuries
Thoracic Surgery
Canidae
Hippocampus

Dendrimer Brain Uptake and Targeted Therapy for Brain Injury in a Large Animal Model of Hypothermic Circulatory Arrest

Mishra, M. K., Beaty, C. A., Lesniak, W. G., Kambhampati, S. P., Zhang, F., Wilson, M. A., Blue, M. E., Troncoso, J. C., Kannan, S., Johnston, M. V., Baumgartner, W. A. & Kannan, R. M. Mar 25 2014 In : ACS Nano. 8, 3, p. 2134-2147 14 p.

Research output: Research - peer-reviewArticle

brain damage
animal models
dendrimers
brain
therapy

Selective expression of Narp in primary nociceptive neurons: Role in microglia/macrophage activation following nerve injury

Miskimon, M., Han, S., Lee, J. J., Ringkamp, M., Wilson, M. A., Petralia, R. S., Dong, X., Worley, P. F., Baraban, J. M. & Reti, I. M. 2014 In : Journal of Neuroimmunology. 274, 1-2, p. 86-95 10 p.

Research output: Research - peer-reviewArticle

Nociceptors
Macrophage Activation
Spinal Ganglia
Microglia
Neurons
2013

Ischemia-induced neuroinflammation is associated with disrupted development of oligodendrocyte progenitors in a model of periventricular leukomalacia

Falahati, S., Breu, M., Waickman, A. T., Phillips, A. W., Arauz, E. J., Snyder, S., Porambo, M., Goeral, K., Comi, A. M., Wilson, M. A., Johnston, M. V. & Fatemi, A. Jul 2013 In : Developmental Neuroscience. 35, 2-3, p. 182-196 15 p.

Research output: Research - peer-reviewArticle

Periventricular Leukomalacia
Oligodendroglia
Stem Cells
Ischemia
Ligation
2011

In vivo magnetization transfer MRI shows dysmyelination in an ischemic mouse model of periventricular leukomalacia

Fatemi, A., Wilson, M. A., Phillips, A. W., McMahon, M. T., Zhang, J., Smith, S. A., Arauz, E. J., Falahati, S., Gummadavelli, A., Bodagala, H., Mori, S. & Johnston, M. V. Oct 2011 In : Journal of Cerebral Blood Flow and Metabolism. 31, 10, p. 2009-2018 10 p.

Research output: Research - peer-reviewArticle

Periventricular Leukomalacia
Magnetic Resonance Imaging
Corpus Callosum
White Matter
Internal Capsule

Serum levels of neuron-specific ubiquitin carboxyl-terminal esterase-L1 predict brain injury in a canine model of hypothermic circulatory arrest

Arnaoutakis, G. J., George, T. J., Wang, K. K., Wilson, M. A., Allen, J. G., Robinson, C. W., Haggerty, K. A., Weiss, E. S., Blue, M. E., Talbot, C. C., Troncoso, J. C., Johnston, M. V. & Baumgartner, W. A. Oct 2011 In : Journal of Thoracic and Cardiovascular Surgery. 142, 4

Research output: Research - peer-reviewArticle

Esterases
Ubiquitin
Brain Injuries
Canidae
Neurons

Sex-specific activation of cell death signalling pathways in cerebellar granule neurons exposed to oxygen glucose deprivation followed by reoxygenation

Sharma, J., Nelluru, G., Wilson, M. A., Johnston, M. V. & Hossain, M. A. 2011 In : ASN Neuro. 3, 2, p. 85-97 13 p.

Research output: Research - peer-reviewArticle

Cell Death
Oxygen
Neurons
Glucose
Caspase 8

Treatment advances in neonatal neuroprotection and neurointensive care

Johnston, M. V., Fatemi, A., Wilson, M. A. & Northington, F. Apr 2011 In : The Lancet Neurology. 10, 4, p. 372-382 11 p.

Research output: Research - peer-reviewArticle

Hypothermia
Brain
Therapeutics
Neuroprotection
Brain Hypoxia-Ischemia
2010

Transcriptional Profile of Brain Injury in Hypothermic Circulatory Arrest and Cardiopulmonary Bypass

Allen, J. G., Weiss, E. S., Wilson, M. A., Arnaoutakis, G. J., Blue, M. E., Talbot, C. C., Jie, C., Lange, M. S., Troncoso, J. C., Johnston, M. V. & Baumgartner, W. A. Jun 2010 In : Annals of Thoracic Surgery. 89, 6, p. 1965-1971 7 p.

Research output: Research - peer-reviewArticle

Cardiopulmonary Bypass
Brain Injuries
Dogs
Genes
Nervous System
2009

Alpha II-Spectrin Breakdown Products Serve as Novel Markers of Brain Injury Severity in a Canine Model of Hypothermic Circulatory Arrest

Weiss, E. S., Wang, K. K. W., Allen, J. G., Blue, M. E., Nwakanma, L. U., Liu, M. C., Lange, M. S., Berrong, J., Wilson, M. A., Gott, V. L., Troncoso, J. C., Hayes, R. L., Johnston, M. V. & Baumgartner, W. A. Aug 2009 In : Annals of Thoracic Surgery. 88, 2, p. 543-550 8 p.

Research output: Research - peer-reviewArticle

Spectrin
Brain Injuries
Canidae
dicesium N-succinimidyl 3-(undecahydrododecaboranyldithio)propionate
Calpain

Hypoxic-Ischemic Encephalopathy in the Term Infant

Fatemi, A., Wilson, M. A. & Johnston, M. V. Dec 2009 In : Clinics in Perinatology. 36, 4, p. 835-858 24 p.

Research output: Research - peer-reviewArticle

Brain Hypoxia-Ischemia
Ischemia
Therapeutics
Hypoxia
Cerebral Palsy
Brain Injuries
Ligation
Seizures
Wounds and Injuries
Stroke
2007

Global gene expression in the developing rat brain after hypoxic preconditioning: Involvement of apoptotic mechanisms?

Gustavsson, M., Wilson, M. A., Mallard, C., Rousset, C., Johnston, M. V. & Hagberg, H. Apr 2007 In : Pediatric Research. 61, 4, p. 444-450 7 p.

Research output: Research - peer-reviewArticle

Gene Expression
Brain
Genes
Hypoxia
Phosphatidylinositol 3-Kinases

Vascular response to hypoxic preconditioning in the immature brain

Gustavsson, M., Mallard, C., Vannucci, S. J., Wilson, M. A., Johnston, M. V. & Hagberg, H. May 16 2007 In : Journal of Cerebral Blood Flow and Metabolism. 27, 5, p. 928-938 11 p.

Research output: Research - peer-reviewArticle

Cerebrovascular Circulation
Blood Vessels
Brain
Hypoxia
Laser-Doppler Flowmetry
2006

Dextromethorphan protects male but not female mice with brain ischemia

Comi, A. M., Highet, B. H., Mehta, P., Hana Chong, T., Johnston, M. V. & Ann Wilson, M. Aug 2006 In : NeuroReport. 17, 12, p. 1319-1322 4 p.

Research output: Research - peer-reviewArticle

Dextromethorphan
Brain Ischemia
Brain Injuries
Ligation
Wounds and Injuries
2005

Immature mouse unilateral carotid ligation model of stroke

Comi, A. M., Johnston, M. V. & Wilson, M. A. Dec 2005 In : Journal of Child Neurology. 20, 12, p. 980-983 4 p.

Research output: Research - peer-reviewArticle

Cerebral Palsy
Ligation
Seizures
Stroke
Wounds and Injuries
Seizures
Stroke
Wounds and Injuries
Brain
Brain Injuries
2004

Activity-dependent expression of Egr1 mRNA in somatosensory cortex of developing rats

Patra, R. C., Blue, M. E., Johnston, M. V., Bressler, J. & Wilson, M. A. Oct 15 2004 In : Journal of Neuroscience Research. 78, 2, p. 235-244 10 p.

Research output: Research - peer-reviewArticle

Somatosensory Cortex
Messenger RNA
Vibrissae
Transcription Factors
Magnetic Fields

A new model of stroke and ischemic seizures in the immature mouse

Comi, A. M., Weisz, C. J. C., Highet, B. H., Johnston, M. V. & Wilson, M. A. Oct 2004 In : Pediatric Neurology. 31, 4, p. 254-257 4 p.

Research output: Research - peer-reviewArticle

Brain Injuries
Ligation
Seizures
Stroke
Carotid Arteries

Minocycline worsens hypoxic-ischemic brain injury in a neonatal mouse model

Tsuji, M., Wilson, M. A., Lange, M. S. & Johnston, M. V. Sep 2004 In : Experimental Neurology. 189, 1, p. 58-65 8 p.

Research output: Research - peer-reviewArticle

Minocycline
Brain Injuries
Anti-Bacterial Agents
Pharmaceutical Preparations
Therapeutics

PARP-1 gene disruption in mice preferentially protects males from perinatal brain injury

Hagberg, H., Wilson, M. A., Matsushita, H., Zhu, C., Lange, M., Gustavsson, M., Poitras, M. F., Dawson, T. M., Dawson, V. L., Northington, F. & Johnston, M. V. Sep 2004 In : Journal of Neurochemistry. 90, 5, p. 1068-1075 8 p.

Research output: Research - peer-reviewArticle

Brain Injuries
Ischemia
Genes
Brain
Hypoxia
2003

Protective effect of erythropoietin in neonatal hypoxic ischemia in mice

Matsushita, H., Johnston, M. V., Lange, M. S. & Wilson, M. A. Sep 15 2003 In : NeuroReport. 14, 13, p. 1757-1761 5 p.

Research output: Research - peer-reviewArticle

Erythropoietin
Ischemia
Hippocampus
Wounds and Injuries
Neuroprotective Agents
2001

Age-dependent effects of trihexyphenidyl in extrapyramidal cerebral palsy

Hoon, A. H., Freese, P. O., Reinhardt, E. M., Wilson, M. A., Lawrie, W. T., Harryman, S. E., Pidcock, F. S. & Johnston, M. V. 2001 In : Pediatric Neurology. 25, 1, p. 55-58 4 p.

Research output: Research - peer-reviewArticle

Trihexyphenidyl
Cerebral Palsy
Language
Upper Extremity
Sialorrhea
2000

Apoptosis has a prolonged role in the neurodegeneration after hypoxic ischemia in the newborn rat

Nakajima, W., Ishida, A., Lange, M. S., Gabrielson, K. L., Wilson, M. A., Martin, L. J., Blue, M. E. & Johnston, M. V. Nov 1 2000 In : Journal of Neuroscience. 20, 21, p. 7994-8004 11 p.

Research output: Research - peer-reviewArticle

Ischemia
Apoptosis
Hypoxia
Caspase 3
Neurons
Rodentia
Lead
Neocortex
Vibrissae
Sensory Receptor Cells
Metals
Ions
Brain
Metal ions
Rats
1998

Expression of NMDA receptor subunit mRNA after MK-801 treatment in neonatal rats

Wilson, M. A., Kinsman, S. L. & Johnston, M. V. Aug 8 1998 In : Developmental Brain Research. 109, 2, p. 211-220 10 p.

Research output: Research - peer-reviewArticle

Dizocilpine Maleate
N-Methyl-D-Aspartate Receptors
Messenger RNA
N-Methylaspartate
Wounds and Injuries

Human FGF-1 gene delivery protects against quinolinate-induced striatal and hippocampal injury in neonatal rats

Hossain, M. A., Fielding, K. E., Trescher, W. H., Ho, T., Wilson, M. A. & Laterra, J. 1998 In : European Journal of Neuroscience. 10, 8, p. 2490-2499 10 p.

Research output: Research - peer-reviewArticle

Quinolinic Acid
Corpus Striatum
Fibroblast Growth Factor 1
Wounds and Injuries
Genes

IL-10 gene transfer to intracranial 9L glioma: Tumor inhibition and cooperation with IL-2

Book, A. A., Fielding, K. E., Kundu, N., Wilson, M. A., Fulton, A. M. & Laterra, J. Dec 1998 In : Journal of Neuroimmunology. 92, 1-2, p. 50-59 10 p.

Research output: Research - peer-reviewArticle

Glioma
Interleukin-10
Interleukin-2
Genes
Neoplasms
1996

Delivery of human fibroblast growth factor-1 gene to brain by modified rat brain endothelial cells

Johnston, P., Nam, M., Hossain, M. A., Indurti, R. R., Mankowski, J. L., Wilson, M. A. & Laterra, J. Oct 1996 In : Journal of Neurochemistry. 67, 4, p. 1643-1652 10 p.

Research output: Research - peer-reviewArticle

Fibroblast Growth Factor 1
Fibroblast Growth Factors
Endothelial Cells
Brain
Genes

Endothelial cell-based cytokine gene delivery inhibits 9L glioma growth in vivo

Nam, M., Johnston, P., Lal, B., Indurti, R., Wilson, M. A. & Laterra, J. Aug 26 1996 In : Brain Research. 731, 1-2, p. 161-170 10 p.

Research output: Research - peer-reviewArticle

Glioma
Endothelial Cells
Cytokines
Growth
Genes
1994

Microglial response to degeneration of serotonergic axon terminals

Wilson, M. A. & Molliver, M. E. May 1994 In : GLIA. 11, 1, p. 18-34 17 p.

Research output: Research - peer-reviewArticle

1993

Reactions of 5-HT neurons to drugs of abuse: neurotoxicity and plasticity.

Wilson, M. A., Mamounas, L. A., Fasman, K. H., Axt, K. J. & Molliver, M. E. 1993 In : NIDA research monograph. 136, p. 155-178 24 p.

Research output: Research - peer-reviewArticle

1992

Dexfenfluramine and neurotoxicity

Baumgarten, G., Garattini, S., Lorens, S., Wurtman, R., Blundell, J., Nicolaidis, S., Kalia, M., Guy-Grand, B., Apfelbaum, M., Crepaldi, G., Gries, A., Lefebvre, P., Turner, P., Ricaurte, G., Molliver, M., Martello, M., Katz, J., Wilson, M. & Martello, A. Feb 8 1992 In : The Lancet. 339, 8789, p. 359-361 3 p.

Research output: Research - peer-reviewArticle

1991

Dexfenfluramine neurotoxicity in brains of non-human primates

Ricaurte, G. A., Martello, M. B., Martello, A. L., Wilson, M. A., Molliver, M. E. & Katz, J. L. Dec 14 1991 In : The Lancet. 338, 8781, p. 1487-1488 2 p.

Research output: Research - peer-reviewArticle

Dexfenfluramine
Primates
Serotonin
Brain
Axons

The organization of serotonergic projections to cerebral cortex in primates: Regional distribution of axon terminals

Wilson, M. A. & Molliver, M. E. 1991 In : Neuroscience. 44, 3, p. 537-553 17 p.

Research output: Research - peer-reviewArticle

Presynaptic Terminals
Cerebral Cortex
Primates
Axons
Serotonin

The organization of serotonergic projections to cerebral cortex in primates: Retrograde transport studies

Wilson, M. A. & Molliver, M. E. 1991 In : Neuroscience. 44, 3, p. 555-570 16 p.

Research output: Research - peer-reviewArticle

Cerebral Cortex
Primates
Neurons
Dorsal Raphe Nucleus
Motor Cortex
1990

Neurotoxicity of MDMA and related compounds: Anatomic studies

Molliver, M. E., Berger, U. V., Mamounas, L. A., Molliver, D. C., O'Hearn, E. & Wilson, M. A. 1990 In : Annals of the New York Academy of Sciences. 600, p. 640-664 25 p.

Research output: Research - peer-reviewArticle

Degeneration
N-Methyl-3,4-methylenedioxyamphetamine
Serotonin
Axons
Drugs

Neurotoxicity of MDMA and related compounds: anatomic studies.

Molliver, M. E., Berger, U. V., Mamounas, L. A., Molliver, D. C., O'Hearn, E. & Wilson, M. A. 1990 In : Annals of the New York Academy of Sciences. 600, p. 649-661 13 p.

Research output: Research - peer-reviewArticle

Degeneration
N-Methyl-3,4-methylenedioxyamphetamine
Serotonin
Axons
Drugs
1989
N-Methyl-3,4-methylenedioxyamphetamine
Psychotropic Drugs
Primates
Axons
Presynaptic Terminals

Effects of neurotoxic amphetamines on serotonergic neurons: immunocytochemical studies.

Molliver, M. E., Mamounas, L. A. & Wilson, M. A. 1989 In : NIDA research monograph. 94, p. 270-305 36 p.

Research output: Research - peer-reviewArticle

1988

(±3,4-Methylenedioxymethamphetamine Selectively Damages Central Serotonergic Neurons in Nonhuman Primates

Ricaurte, G. A., Forno, L. S., Wilson, M. A., Delanney, L. E., Irwin, I., Molliver, M. E. & Langston, J. W. Jul 1 1988 In : Journal of the American Medical Association. 260, 1, p. 51-55 5 p.

Research output: Research - peer-reviewArticle

Serotonergic Neurons
N-Methyl-3,4-methylenedioxyamphetamine
Primates
Hydroxyindoleacetic Acid
Haplorhini