Mark A Riddle

Professor

1973 …2018
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Research Output 1973 2018

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Article
2018

Analysis of shared heritability in common disorders of the brain

The Brainstorm Consortium, Jun 22 2018, In : Science. 360, 6395, 8757.

Research output: Contribution to journalArticle

Brain Diseases
Psychiatry
Phenotype
Genetic Heterogeneity
Genome-Wide Association Study

Interpersonal psychotherapy for mood and behavior dysregulation: Pilot randomized trial

Miller, L., Hlastala, S. A., Mufson, L., Leibenluft, E., Yenokyan, G. & Riddle, M. A., Jan 1 2018, (Accepted/In press) In : Depression and Anxiety.

Research output: Contribution to journalArticle

Psychotherapy
Mood Disorders
Group Psychotherapy
Parents
Therapeutics

Revealing the complex genetic architecture of obsessive-compulsive disorder using meta-analysis

International Obsessive Compulsive Disorder Foundation Genetics Collaborative (IOCDF-GC) & OCD Collaborative Genetics Association Studies (OCGAS), May 1 2018, In : Molecular Psychiatry. 23, 5, p. 1181-1188 8 p.

Research output: Contribution to journalArticle

Obsessive-Compulsive Disorder
Meta-Analysis
Genetic Association Studies
Single Nucleotide Polymorphism
Genome-Wide Association Study

Self-reported executive function and hoarding in adults with obsessive-compulsive disorder

Samuels, J., Bienvenu, O. J., Krasnow, J., Wang, Y., Grados, M., Cullen, B., Goes, F. S., Maher, B., Greenberg, B. D., McLaughlin, N. C., Rasmussen, S. A., Fyer, A. J., Knowles, J. A., McCracken, J. T., Piacentini, J., Geller, D., Pauls, D. L., Stewart, S. E., Murphy, D. L., Shugart, Y. Y. & 2 others, Riddle, M. A. & Nestadt, G., Feb 1 2018, In : Comprehensive Psychiatry. 81, p. 53-59 7 p.

Research output: Contribution to journalArticle

Obsessive-Compulsive Disorder
Executive Function
Hoarding
Aptitude
Personality Disorders
2017

An investigation of doubt in obsessive–compulsive disorder

Samuels, J., Bienvenu, O. J., Krasnow, J., Wang, Y., Grados, M., Cullen, B., Goes, F. S., Maher, B., Greenberg, B. D., McLaughlin, N. C., Rasmussen, S. A., Fyer, A. J., Knowles, J. A., Nestadt, P., McCracken, J. T., Piacentini, J., Geller, D., Pauls, D. L., Stewart, S. E., Murphy, D. L. & 5 others, Shugart, Y. Y., Kamath, V., Bakker, A., Riddle, M. A. & Nestadt, G., May 1 2017, In : Comprehensive Psychiatry. 75, p. 117-124 8 p.

Research output: Contribution to journalArticle

Personality Disorders
Dependent Personality Disorder
Anxiety Disorders
Age of Onset
Depression

Genome wide association study (GWAS) between attention deficit hyperactivity disorder (ADHD) and obsessive compulsive disorder (OCD)

Ritter, M. L., Guo, W., Samuel, J. F., Wang, Y., Nestadt, P., Krasnow, J., Greenberg, B. D., Fyer, A. J., McCracken, J. T., Geller, D. A., Murphy, D. L., Knowles, J. A., Grados, M., Riddle, M. A., Rasmussen, S. A., McLaughlin, N. C., Nurmi, E. L., Askland, K. D., Cullen, B., Piacentini, J. & 10 others, Pauls, D. L., Bienvenu, O. J., Stewart, E., Goes, F. S., Maher, B., Pulver, A. E., Mattheisen, M., Qian, J., Nestadt, G. & Shugart, Y. Y., Mar 23 2017, In : Frontiers in Molecular Neuroscience. 10, 83.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Obsessive-Compulsive Disorder
Attention Deficit Disorder with Hyperactivity
Proteins
Single Nucleotide Polymorphism

Parental bonding and hoarding in obsessive–compulsive disorder

Chen, D., Bienvenu, O. J., Krasnow, J., Wang, Y., Grados, M., Cullen, B., Goes, F. S., Maher, B., Greenberg, B. D., McLaughlin, N. C., Rasmussen, S. A., Fyer, A. J., Knowles, J. A., McCracken, J. T., Piacentini, J., Geller, D., Pauls, D. L., Stewart, S. E., Murphy, D. L., Shugart, Y. Y. & 3 others, Riddle, M. A., Nestadt, G. & Samuels, J., Feb 1 2017, In : Comprehensive Psychiatry. 73, p. 43-52 10 p.

Research output: Contribution to journalArticle

Mothers
Parenting
Object Attachment
Hoarding
Personality Disorders

Polygenic risk score and heritability estimates reveals a genetic relationship between ASD and OCD

Guo, W., Samuels, J., Wang, Y., Cao, H., Ritter, M., Nestadt, P., Krasnow, J., Greenberg, B. D., Fyer, A. J., McCracken, J. T., Geller, D. A., Murphy, D. L., Knowles, J. A., Grados, M., Riddle, M. A., Rasmussen, S. A., McLaughlin, N. C., Nurmi, E. L., Askland, K. D., Cullen, B. A. & 12 others, Piacentini, J., Pauls, D. L., Bienvenu, O. J., Stewart, S. E., Goes, F. S., Maher, B., Pulver, A. E., Valle, D., Mattheisen, M., Qian, J., Nestadt, G. & Shugart, Y. Y., Jul 1 2017, In : European Neuropsychopharmacology. 27, 7, p. 657-666 10 p.

Research output: Contribution to journalArticle

Obsessive-Compulsive Disorder
Genome-Wide Association Study
Genome
Chromosomes, Human, Pair 16
Nuclear Family
2016

ADHD and executive functioning deficits in OCD youths who hoard

Park, J. M., Samuels, J., Grados, M., Riddle, M. A., Bienvenu, O. J., Goes, F. S., Cullen, B., Wang, Y., Krasnow, J., Murphy, D. L., Rasmussen, S. A., McLaughlin, N. C., Piacentini, J., Pauls, D. L., Stewart, S. E., Shugart, Y. Y., Maher, B., Pulver, A. E., Knowles, J. A., Greenberg, B. D. & 4 others, Fyer, A. J., McCracken, J. T., Nestadt, G. & Geller, D. A., Nov 1 2016, In : Journal of Psychiatric Research. 82, p. 141-148 8 p.

Research output: Contribution to journalArticle

Obsessive-Compulsive Disorder
Attention Deficit Disorder with Hyperactivity
Hoarding
Attention Deficit Hyperactivity Disorder
Hoard

Dependent personality, separation anxiety disorder and other anxiety disorders in OCD

Mroczkowski, M. M., Goes, F. S., Riddle, M. A., Grados, M., Bienvenu, O. J., Greenberg, B. D., Fyer, A. J., Mccracken, J. T., Rauch, S. L., Murphy, D. L., Knowles, J. A., Piacentini, J., Cullen, B., Rasmussen, S. A., Pauls, D. L., Nestadt, G. & Samuels, J., Feb 1 2016, In : Personality and Mental Health. 10, 1, p. 22-28 7 p.

Research output: Contribution to journalArticle

Separation Anxiety
Obsessive-Compulsive Disorder
Anxiety Disorders
Personality
Dependent Personality Disorder

OBSESSIVE-COMPULSIVE PERSONALITY DISORDER: EVIDENCE for TWO DIMENSIONS

Riddle, M. A., Maher, B., Wang, Y., Grados, M., Bienvenu, O. J., Goes, F. S., Cullen, B., Murphy, D. L., Rauch, S. L., Greenberg, B. D., Knowles, J. A., McCracken, J. T., Pinto, A., Piacentini, J., Pauls, D. L., Rasmussen, S. A., Shugart, Y. Y., Nestadt, G. & Samuels, J., Feb 1 2016, In : Depression and Anxiety. 33, 2, p. 128-135 8 p.

Research output: Contribution to journalArticle

Compulsive Personality Disorder
Obsessive-Compulsive Disorder
Diagnostic and Statistical Manual of Mental Disorders
Genetic Linkage
Quantitative Trait Loci

Whole-genome association analysis of treatment response in obsessive-compulsive disorder

Qin, H., Samuels, J., Wang, Y., Zhu, Y., Grados, M., Riddle, M. A., Greenberg, B. D., Knowles, J. A., Fyer, A. J., McCracken, J. T., Murphy, D. L., Rasmussen, S. A., Cullen, B. A., Piacentini, J., Geller, D., Stewart, S. E., Pauls, D., Bienvenu, O. J., Goes, F. S., Maher, B. & 10 others, Pulver, A. E., Valle, D., Lange, C., Mattheisen, M., McLaughlin, N. C., Liang, K. Y., Nurmi, E. L., Askland, K. D., Nestadt, G. & Shugart, Y. Y., Feb 1 2016, In : Molecular Psychiatry. 21, 2, p. 270-276 7 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Obsessive-Compulsive Disorder
Serotonin Uptake Inhibitors
Single Nucleotide Polymorphism
Therapeutics
2015
Bulimia
Attention Deficit Disorder with Hyperactivity
Mental Health
Pediatrics
Obesity

Awareness, attitudes, and use of crisis hotlines among youth at-risk for suicide

Budinger, M. C., Cwik, M. & Riddle, M. A., Apr 1 2015, In : Suicide and Life-Threatening Behavior. 45, 2, p. 192-198 7 p.

Research output: Contribution to journalArticle

Hotlines
Suicide

Child/adolescent anxiety multimodal study: Evaluating safety

Rynn, M. A., Walkup, J. T., Compton, S. N., Sakolsky, D. J., Sherrill, J. T., Shen, S., Kendall, P. C., McCracken, J., Albano, A. M., Piacentini, J., Riddle, M. A., Keeton, C., Waslick, B., Chrisman, A., Iyengar, S., March, J. S. & Birmaher, B., Mar 1 2015, In : Journal of the American Academy of Child and Adolescent Psychiatry. 54, 3, p. 180-190 11 p.

Research output: Contribution to journalArticle

Psychiatry
Anxiety
Separation Anxiety
Safety
Sertraline

Depression and Suicidality Outcomes in the Treatment of Early Age Mania Study

Salpekar, J. A., Joshi, P. T., Axelson, D. A., Reinblatt, S., Yenokyan, G., Sanyal, A., Walkup, J. T., Vitiello, B., Luby, J. L., Wagner, K. D., Nusrat, N. & Riddle, M. A., 2015, In : Journal of the American Academy of Child and Adolescent Psychiatry. 54, 12, p. 999-1007.e4

Research output: Contribution to journalArticle

Lithium Carbonate
Risperidone
Bipolar Disorder
Depression
Outcome Assessment (Health Care)

Genome-wide association study in obsessive-compulsive disorder: Results from the OCGAS

Mattheisen, M., Samuels, J., Wang, Y., Greenberg, B. D., Fyer, A. J., Mccracken, J. T., Geller, D. A., Murphy, D. L., Knowles, J. A., Grados, M., Riddle, M. A., Rasmussen, S. A., Mclaughlin, N. C., Nurmi, E. L., Askland, K. D., Qin, H. D., Cullen, B. A., Piacentini, J., Pauls, D. L., Bienvenu, O. J. & 9 others, Stewart, S. E., Liang, K. Y., Goes, F. S., Maher, B., Pulver, A. E., Shugart, Y. Y., Valle, D., Lange, C. & Nestadt, G., Mar 12 2015, In : Molecular Psychiatry. 20, 3, p. 337-344 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Obsessive-Compulsive Disorder
Genetic Association Studies
Synapses
Single Nucleotide Polymorphism
Impulsive Behavior
Attention Deficit Disorder with Hyperactivity
Eating
Pediatrics
Odds Ratio

Pharmacotherapy of the Preschool ADHD Treatment Study (PATS) Children Growing Up

Vitiello, B., Lazzaretto, D., Yershova, K., Abikoff, H., Paykina, N., McCracken, J. T., McGough, J. J., Kollins, S. H., Greenhill, L. L., Wigal, S., Wigal, T. & Riddle, M. A., Jul 1 2015, In : Journal of the American Academy of Child and Adolescent Psychiatry. 54, 7, p. 550-556 7 p., 1204.

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Drug Therapy
Antipsychotic Agents
Therapeutics
Attention Deficit and Disruptive Behavior Disorders

Preventing onset of anxiety disorders in offspring of anxious parents: A randomized controlled trial of a family-based intervention

Ginsburg, G. S., Drake, K., Tein, J. Y., Teetsel, R. & Riddle, M. A., Dec 1 2015, In : American Journal of Psychiatry. 172, 12, p. 1207-1214 8 p.

Research output: Contribution to journalArticle

Anxiety Disorders
Randomized Controlled Trials
Parents
Anxiety
Interviews

The Family Value of Information, Community Support, and Experience Study: Rationale, Design, and Methods of a "family-Centered" Research Study

Reeves, G. M., Wehring, H. J., Connors, K. M., Bussell, K., Schiffman, J., Medoff, D. R., Tsuji, T., Walker, J., Brown, A., Strobeck, D., Clough, T., Rush, C. B., Riddle, M. A., Love, R. C., Zachik, A. A., Hoagwood, K., Olin, S. S., Stephan, S., Okuzawa, N., Edwards, S. & 2 others, Baquet, C. & DosReis, S., Dec 1 2015, In : Journal of Nervous and Mental Disease. 203, 12, p. 896-900 5 p.

Research output: Contribution to journalArticle

Mental Health Services
Antipsychotic Agents
Parents
Patient Protection and Affordable Care Act
Child Health Services

Treatment of Early-Age Mania: Outcomes for Partial and Nonresponders to Initial Treatment

Walkup, J. T., Wagner, K. D., Miller, L., Yenokyan, G., Luby, J. L., Joshi, P. T., Axelson, D. A., Robb, A., Salpekar, J. A., Wolf, D., Sanyal, A., Birmaher, B., Vitiello, B. & Riddle, M. A., 2015, In : Journal of the American Academy of Child and Adolescent Psychiatry. 54, 12, p. 1008-1019 12 p.

Research output: Contribution to journalArticle

Antimanic Agents
Valproic Acid
Bipolar Disorder
Risperidone
Numbers Needed To Treat
2014

A practical and effective primary care intervention for treating adolescent depression

Reeves, G. M. & Riddle, M. A., Aug 27 2014, In : Journal of the American Medical Association. 312, 8, p. 797-798 2 p.

Research output: Contribution to journalArticle

Patient Care Team
Primary Health Care

Clinical correlates and genetic linkage of social and communication difficulties in families with obsessive-compulsive disorder: Results from the OCD collaborative genetics study

Samuels, J., Shugart, Y. Y., Wang, Y., Grados, M., Bienvenu, O. J., Pinto, A., Rauch, S. L., Greenberg, B. D., Knowles, J. A., Fyer, A. J., Piacentini, J., Pauls, D. L., Cullen, B., Rasmussen, S. A., Stewart, S. E., Geller, D. A., Maher, B., Goes, F. S., Murphy, D. L., Mccracken, J. T. & 2 others, Riddle, M. A. & Nestadt, G., 2014, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 165, 4, p. 326-336 11 p.

Research output: Contribution to journalArticle

Genetic Linkage
Obsessive-Compulsive Disorder
Communication
Separation Anxiety
Chromosomes, Human, Pair 12

Copy number variation in obsessive-compulsive disorder and tourette syndrome: A cross-disorder study

McGrath, L. M., Yu, D., Marshall, C., Davis, L. K., Thiruvahindrapuram, B., Li, B., Cappi, C., Gerber, G., Wolf, A., Schroeder, F. A., Osiecki, L., O'Dushlaine, C., Kirby, A., Illmann, C., Haddad, S., Gallagher, P., Fagerness, J. A., Barr, C. L., Bellodi, L., Benarroch, F. & 101 others, Bienvenu, O. J., Black, D. W., Bloch, M. H., Bruun, R. D., Budman, C. L., Camarena, B., Cath, D. C., Cavallini, M. C., Chouinard, S., Coric, V., Cullen, B., Delorme, R., Denys, D., Derks, E. M., Dion, Y., Rosário, M. C., Eapen, V., Evans, P., Falkai, P., Fernandez, T. V., Garrido, H., Geller, D., Grabe, H. J., Grados, M., Greenberg, B. D., Gross-Tsur, V., Grünblatt, E., Heiman, G. A., Hemmings, S. M. J., Herrera, L. D., Hounie, A. G., Jankovic, J., Kennedy, J. L., King, R. A., Kurlan, R., Lanzagorta, N., Leboyer, M., Leckman, J. F., Lennertz, L., Lochner, C., Lowe, T. L., Lyon, G. J., MacCiardi, F., Maier, W., McCracken, J. T., McMahon, W., Murphy, D. L., Naarden, A. L., Neale, B. M., Nurmi, E., Pakstis, A. J., Pato, M. T., Pato, C. N., Piacentini, J., Pittenger, C., Pollak, Y., Reus, V. I., Richter, M. A., Riddle, M. A., Robertson, M. M., Rosenberg, D., Rouleau, G. A., Ruhrmann, S., Sampaio, A. S., Samuels, J., Sandor, P., Sheppard, B., Singer, H., Smit, J. H., Stein, D. J., Tischfield, J. A., Vallada, H., Veenstra-Vanderweele, J., Walitza, S., Wang, Y., Wendland, J. R., Shugart, Y. Y., Miguel, E. C., Nicolini, H., Oostra, B. A., Moessner, R., Wagner, M., Ruiz-Linares, A., Heutink, P., Nestadt, G., Freimer, N., Petryshen, T., Posthuma, D., Jenike, M. A., Cox, N. J., Hanna, G. L., Brentani, H., Scherer, S. W., Arnold, P. D., Stewart, S. E., Mathews, C. A., Knowles, J. A., Cook, E. H., Pauls, D. L., Wang, K. & Scharf, J. M., 2014, In : Journal of the American Academy of Child and Adolescent Psychiatry. 53, 8, p. 910-919 10 p.

Research output: Contribution to journalArticle

Tourette Syndrome
Obsessive-Compulsive Disorder
Genome
Neurodevelopmental Disorders

Hoarding in children and adolescents with obsessive-compulsive disorder

Samuels, J., Grados, M., Riddle, M. A., Bienvenu, O. J., Goes, F. S., Cullen, B., Wang, Y., Greenberg, B. D., Fyer, A. J., McCracken, J. T., Geller, D., Murphy, D. L., Knowles, J. A., Rasmussen, S. A., McLaughlin, N. C., Piacentini, J., Pauls, D. L., Stewart, S. E., Shugart, Y. Y., Maher, B. & 2 others, Pulver, A. E. & Nestadt, G., Oct 1 2014, In : Journal of Obsessive-Compulsive and Related Disorders. 3, 4, p. 325-331 7 p.

Research output: Contribution to journalArticle

Obsessive-Compulsive Disorder
Age of Onset
Obsessive Behavior
Tics
Tourette Syndrome
2013
Residential Facilities
Adolescent Behavior
aggressive behavior
Antipsychotic Agents
medication

Genome-wide association study of obsessive-compulsive disorder

Stewart, S. E., Yu, D., Scharf, J. M., Neale, B. M., Fagerness, J. A., Mathews, C. A., Arnold, P. D., Evans, P. D., Gamazon, E. R., Osiecki, L., McGrath, L., Haddad, S., Crane, J., Hezel, D., Illman, C., Mayerfeld, C., Konkashbaev, A., Liu, C., Pluzhnikov, A., Tikhomirov, A. & 111 others, Edlund, C. K., Rauch, S. L., Moessner, R., Falkai, P., Maier, W., Ruhrmann, S., Grabe, H. J., Lennertz, L., Wagner, M., Bellodi, L., Cavallini, M. C., Richter, M. A., Cook, E. H., Kennedy, J. L., Rosenberg, D., Stein, D. J., Hemmings, S. M. J., Lochner, C., Azzam, A., Chavira, D. A., Fournier, E., Garrido, H., Sheppard, B., Umaña, P., Murphy, D. L., Wendland, J. R., Veenstra-Vanderweele, J., Denys, D., Blom, R., Deforce, D., Van Nieuwerburgh, F., Westenberg, H. G. M., Walitza, S., Egberts, K., Renner, T., Miguel, E. C., Cappi, C., Hounie, A. G., Conceição Do Rosário, M., Sampaio, A. S., Vallada, H., Nicolini, H., Lanzagorta, N., Camarena, B., Delorme, R., Leboyer, M., Pato, C. N., Pato, M. T., Voyiaziakis, E., Heutink, P., Cath, D. C., Posthuma, D., Smit, J. H., Samuels, J., Bienvenu, O. J., Cullen, B., Fyer, A. J., Grados, M., Greenberg, B. D., McCracken, J. T., Riddle, M. A., Wang, Y., Coric, V., Leckman, J. F., Bloch, M., Pittenger, C., Eapen, V., Black, D. W., Ophoff, R. A., Strengman, E., Cusi, D., Turiel, M., Frau, F., MacCiardi, F., Gibbs, J. R., Cookson, M. R., Singleton, A., Arepalli, S., Cookson, M. R., Dillman, A., Ferrucci, L., Gibbs, J. R., Hernandez, D. G., Johnson, R., Longo, D. L., Nalls, M. A., O'Brien, R., Singleton, A., Traynor, B., Troncoso, J. C., Van Der Brug, M., Zielke, H. R., Zonderman, A., Hardy, J., Crenshaw, A. T., Parkin, M. A., Mirel, D. B., Conti, D. V., Purcell, S., Nestadt, G., Hanna, G. L., Jenike, M. A., Knowles, J. A., Cox, N., Pauls, D. L., Hardy, J. A., Ryten, M., Smith, C., Trabzuni, D., Walker, R. & Weale, M., Jul 2013, In : Molecular Psychiatry. 18, 7, p. 788-798 11 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Obsessive-Compulsive Disorder
Single Nucleotide Polymorphism
Genome
Post-Synaptic Density

Improving metabolic parameters of antipsychotic child treatment (IMPACT) study: Rationale, design, and methods

Reeves, G. M., Keeton, C., Correll, C. U., Johnson, J. L., Hamer, R. M., Sikich, L., Hazzard, L., Alderman, C., Scheer, A., Mabe, M., Kapoor, S., Sheridan, E., Borner, I., Bussell, K., Pirmohamed, S., Bethea, T. C., Chekuri, R., Gottfried, R., Reinblatt, S., Santana, E. & 1 others, Riddle, M. A., Aug 15 2013, In : Child and Adolescent Psychiatry and Mental Health. 7, 1, 31.

Research output: Contribution to journalArticle

Antipsychotic Agents
Weight Gain
Therapeutics
Psychiatry
Pediatrics

Letters to the editor

Vitiello, B., Riddle, M. A., Gayane Yenokyan, Y., Axelson, D. A., Birmaher, B., Ryan, N. D., Wagner, K. D., Joshi, P., Robb, A., Walkup, J. T., Luby, J., Rebecca Tillman, T. & Emslie, G., Feb 2013, In : Journal of the American Academy of Child and Adolescent Psychiatry. 52, 2, p. 206-207 2 p.

Research output: Contribution to journalArticle

Antimanic Agents
Lithium Carbonate
Patient Care Team
Risperidone
Valproic Acid

Meta-analysis of association between obsessive-compulsive disorder and the 3′ region of neuronal glutamate transporter gene SLC1A1

Stewart, S. E., Mayerfeld, C., Arnold, P. D., Crane, J. R., O'Dushlaine, C., Fagerness, J. A., Yu, D., Scharf, J. M., Chan, E., Kassam, F., Moya, P. R., Wendland, J. R., Delorme, R., Richter, M. A., Kennedy, J. L., Veenstra-Vanderweele, J., Samuels, J., Greenberg, B. D., Mccracken, J. T., Knowles, J. A. & 17 others, Fyer, A. J., Rauch, S. L., Riddle, M. A., Grados, M., Bienvenu, O. J., Cullen, B., Wang, Y., Shugart, Y. Y., Piacentini, J., Rasmussen, S., Nestadt, G., Murphy, D. L., Jenike, M. A., Cook, E. H., Pauls, D. L., Hanna, G. L. & Mathews, C. A., Jun 2013, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 162, 4, p. 367-379 13 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
Obsessive-Compulsive Disorder
Meta-Analysis
Genes
Single Nucleotide Polymorphism

Metformin for antipsychotic-related weight gain and metabolic abnormalities: When, for whom, and for how long?

Correll, C. U., Sikich, L., Reeves, G. & Riddle, M. A., Sep 1 2013, In : American Journal of Psychiatry. 170, 9, p. 947-952 6 p.

Research output: Contribution to journalArticle

Metformin
Antipsychotic Agents
Weight Gain

Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture

Davis, L. K., Yu, D., Keenan, C. L., Gamazon, E. R., Konkashbaev, A. I., Derks, E. M., Neale, B. M., Yang, J., Lee, S. H., Evans, P., Barr, C. L., Bellodi, L., Benarroch, F., Berrio, G. B., Bienvenu, O. J., Bloch, M. H., Blom, R. M., Bruun, R. D., Budman, C. L., Camarena, B. & 111 others, Campbell, D., Cappi, C., Cardona Silgado, J. C., Cath, D. C., Cavallini, M. C., Chavira, D. A., Chouinard, S., Conti, D. V., Cook, E. H., Coric, V., Cullen, B. A., Deforce, D., Delorme, R., Dion, Y., Edlund, C. K., Egberts, K., Falkai, P., Fernandez, T. V., Gallagher, P. J., Garrido, H., Geller, D., Girard, S. L., Grabe, H. J., Grados, M., Greenberg, B. D., Gross-Tsur, V., Haddad, S., Heiman, G. A., Hemmings, S. M. J., Hounie, A. G., Illmann, C., Jankovic, J., Jenike, M. A., Kennedy, J. L., King, R. A., Kremeyer, B., Kurlan, R., Lanzagorta, N., Leboyer, M., Leckman, J. F., Lennertz, L., Liu, C., Lochner, C., Lowe, T. L., Macciardi, F., McCracken, J. T., McGrath, L. M., Mesa Restrepo, S. C., Moessner, R., Morgan, J., Muller, H., Murphy, D. L., Naarden, A. L., Ochoa, W. C., Ophoff, R. A., Osiecki, L., Pakstis, A. J., Pato, M. T., Pato, C. N., Piacentini, J., Pittenger, C., Pollak, Y., Rauch, S. L., Renner, T. J., Reus, V. I., Richter, M. A., Riddle, M. A., Robertson, M. M., Romero, R., Rosàrio, M. C., Rosenberg, D., Rouleau, G. A., Ruhrmann, S., Ruiz-Linares, A., Sampaio, A. S., Samuels, J., Sandor, P., Sheppard, B., Singer, H., Smit, J. H., Stein, D. J., Strengman, E., Tischfield, J. A., Valencia Duarte, A. V., Vallada, H., Van Nieuwerburgh, F., Veenstra-VanderWeele, J., Walitza, S., Wang, Y., Wendland, J. R., Westenberg, H. G. M., Shugart, Y. Y., Miguel, E. C., McMahon, W., Wagner, M., Nicolini, H., Posthuma, D., Hanna, G. L., Heutink, P., Denys, D., Arnold, P. D., Oostra, B. A., Nestadt, G., Freimer, N. B., Pauls, D. L., Wray, N. R., Stewart, S. E., Mathews, C. A., Knowles, J. A., Cox, N. J. & Scharf, J. M., Oct 2013, In : PLoS Genetics. 9, 10, e1003864.

Research output: Contribution to journalArticle

obsessive-compulsive disorder
Tourette Syndrome
Obsessive-Compulsive Disorder
heritability
partitioning

Pediatric psychopharmacology in primary care: A conceptual framework

Riddle, M. A., Dos Reis, S., Reeves, G. M., Wissow, L. S., Pruitt, D. B. & Foy, J. M., Aug 2013, In : Adolescent Medicine: State of the Art Reviews. 24, 2, p. 371-390 20 p.

Research output: Contribution to journalArticle

Psychopharmacology
Primary Care Physicians
Attention Deficit Disorder with Hyperactivity
Primary Health Care
Anxiety

The iron status of children and youth in a community mental health clinic is lower than that of a national sample

Gottfried, R. J., Gerring, J. P., MacHell, K., Yenokyan, G. & Riddle, M. A., Mar 1 2013, In : Journal of Child and Adolescent Psychopharmacology. 23, 2, p. 91-100 10 p.

Research output: Contribution to journalArticle

Mental Health
Iron
Ferritins
Psychiatry
Attention Deficit Disorder with Hyperactivity

The preschool attention-deficit/hyperactivity disorder treatment study (PATS) 6-year follow-up

Riddle, M. A., Yershova, K., Lazzaretto, D., Paykina, N., Yenokyan, G., Greenhill, L., Abikoff, H., Vitiello, B., Wigal, T., McCracken, J. T., Kollins, S. H., Murray, D. W., Wigal, S., Kastelic, E. A., McGough, J. J., Dosreis, S., Bauzó-Rosario, A., Stehli, A. & Posner, K., Mar 2013, In : Journal of the American Academy of Child and Adolescent Psychiatry. 52, 3

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Therapeutics
Attention Deficit and Disruptive Behavior Disorders
Conduct Disorder
Mental Disorders
2012

Antipsychotic-induced psychotic-like syndrome and pathological smiling in an adolescent

Burkey, M. D., Howell, C., Riddle, M. A. & Coffey, B. J., Feb 1 2012, In : Journal of Child and Adolescent Psychopharmacology. 22, 1, p. 92-95 4 p.

Research output: Contribution to journalArticle

A randomized controlled trial of risperidone, lithium, or divalproex sodium for initial treatment of bipolar I disorder, manic or mixed phase, in children and adolescents

Geller, B., Luby, J. L., Joshi, P., Wagner, K. D., Emslie, G., Walkup, J. T., Axelson, D. A., Bolhofner, K., Robb, A., Wolf, D. V., Riddle, M. A., Birmaher, B., Nusrat, N., Ryan, N. D., Vitiello, B., Tillman, R. & Lavori, P., May 2012, In : Archives of General Psychiatry. 69, 5, p. 515-528 14 p.

Research output: Contribution to journalArticle

Risperidone
Valproic Acid
Bipolar Disorder
Lithium
Randomized Controlled Trials

Homeobox genes in obsessive-compulsive disorder

Nestadt, G., Wang, Y., Grados, M., Riddle, M. A., Greenberg, B. D., Knowles, J. A., Fyer, A. J., Mccracken, J. T., Rauch, S. L., Murphy, D. L., Rasmussen, S. A., Cullen, B., Piacentini, J., Geller, D., Pauls, D., Bienvenu, O. J., Chen, Y., Liang, K. Y., Goes, F. S., Maher, B. & 5 others, Pulver, A. E., Shugart, Y. Y., Valle, D., Samuels, J. & Chang, Y. C., Jan 2012, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 159 B, 1, p. 53-60 8 p.

Research output: Contribution to journalArticle

Homeobox Genes
Obsessive-Compulsive Disorder
Single Nucleotide Polymorphism
Social Adjustment
Corpus Striatum

Is obsessive-compulsive disorder an anxiety disorder, and what, if any, are spectrum conditions? A family study perspective

Bienvenu, O. J., Samuels, J., Wuyek, L. A., Liang, K. Y., Wang, Y., Grados, M., Cullen, B. A., Riddle, M. A., Greenberg, B. D., Rasmussen, S. A., Fyer, A. J., Pinto, A., Rauch, S. L., Pauls, D. L., McCracken, J. T., Piacentini, J., Murphy, D. L., Knowles, J. A. & Nestadt, G., Jan 2012, In : Psychological Medicine. 42, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Obsessive-Compulsive Disorder
Anxiety Disorders
Disruptive, Impulse Control, and Conduct Disorders
Firesetting Behavior
Trichotillomania

Long-term exposure to oral methylphenidate or dl-amphetamine mixture in peri-adolescent rhesus monkeys: Effects on physiology, behavior, and dopamine system development

Soto, P. L., Wilcox, K. M., Zhou, Y., Ator, N. A., Riddle, M. A., Wong, D. F. & Weed, M. R., Nov 2012, In : Neuropsychopharmacology. 37, 12, p. 2566-2579 14 p.

Research output: Contribution to journalArticle

Methylphenidate
Amphetamine
Macaca mulatta
Dopamine
Dopamine Plasma Membrane Transport Proteins

Treatment moderators and predictors of outcome in the Treatment of Early Age Mania (TEAM) study

Vitiello, B., Riddle, M. A., Yenokyan, G., Axelson, D. A., Wagner, K. D., Joshi, P., Walkup, J. T., Luby, J., Birmaher, B., Ryan, N. D., Emslie, G., Robb, A. & Tillman, R., Sep 2012, In : Journal of the American Academy of Child and Adolescent Psychiatry. 51, 9, p. 867-878 12 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Risperidone
Attention Deficit Disorder with Hyperactivity
Lithium
Valproic Acid
2011

Antipsychotic treatment among youth in foster care

DosReis, S., Yoon, Y., Rubin, D. M., Riddle, M. A., Noll, E. & Rothbard, A., Dec 2011, In : Pediatrics. 128, 6

Research output: Contribution to journalArticle

Antipsychotic Agents
Medicaid
Therapeutics
Mental Disorders
Psychiatry
Compulsive Personality Disorder
Serotonin Plasma Membrane Transport Proteins
Personality Disorders
Alleles
Obsessive-Compulsive Disorder

Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study

Voyiaziakis, E., Evgrafov, O., Li, D., Yoon, H. J., Tabares, P., Samuels, J., Wang, Y., Riddle, M. A., Grados, M., Bienvenu, O. J., Shugart, Y. Y., Liang, K. Y., Greenberg, B. D., Rasmussen, S. A., Murphy, D. L., Wendland, J. R., McCracken, J. T., Piacentini, J., Rauch, S. L., Pauls, D. L. & 3 others, Nestadt, G., Fyer, A. J. & Knowles, J. A., Jan 2011, In : Molecular Psychiatry. 16, 1, p. 108-120 13 p.

Research output: Contribution to journalArticle

Obsessive-Compulsive Disorder
Haplotypes
HapMap Project
Linkage Disequilibrium
Genetic Association Studies

Cognitive functioning in compulsive hoarding

Blom, R. M., Samuels, J., Grados, M., Chen, Y., Bienvenu, O. J., Riddle, M. A., Liang, K. Y., Brandt, J. & Nestadt, G., Dec 2011, In : Journal of Anxiety Disorders. 25, 8, p. 1139-1144 6 p.

Research output: Contribution to journalArticle

Obsessive-Compulsive Disorder
Reaction Time
Decision Making
Gambling
Hoarding

Comprehensive family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder

Samuels, J., Wang, Y., Riddle, M. A., Greenberg, B. D., Fyer, A. J., Mccracken, J. T., Rauch, S. L., Murphy, D. L., Grados, M., Knowles, J. A., Piacentini, J., Cullen, B., Bienvenu, O. J., Rasmussen, S. A., Geller, D., Pauls, D. L., Liang, K. Y., Shugart, Y. Y. & Nestadt, G., Jun 2011, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 156, 4, p. 472-477 6 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
Obsessive-Compulsive Disorder
Single Nucleotide Polymorphism
Genes
Viverridae

Separation anxiety disorder in OCD

Mroczkowski, M. M., Goes, F. S., Riddle, M. A., Grados, M., Bienvenu, O. J., Greenberg, B. D., Fyer, A. J., McCracken, J. T., Rauch, S. L., Murphy, D. L., Knowles, J. A., Piacentini, J., Cullen, B., Rasmussen, S. A., Geller, D. A., Pauls, D. L., Liang, K. Y., Nestadt, G. & Samuels, J., Mar 2011, In : Depression and Anxiety. 28, 3, p. 256-262 7 p.

Research output: Contribution to journalArticle

Separation Anxiety
Obsessive-Compulsive Disorder
Personality Disorders
Anxiety Disorders

The Utility of Clinicians Ratings of Anxiety Using the Pediatric Anxiety Rating Scale (PARS)

Ginsburg, G. S., Keeton, C., Drazdowski, T. K. & Riddle, M. A., Apr 2011, In : Child and Youth Care Forum. 40, 2, p. 93-105 13 p.

Research output: Contribution to journalArticle

rating scale
rating
anxiety
parents