Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 7 Similar Profiles
Enzymes Medicine & Life Sciences
Proteins Medicine & Life Sciences
Peptides Medicine & Life Sciences
Mutation Medicine & Life Sciences
Molecules Chemical Compounds
Substrates Chemical Compounds
Catalytic Domain Medicine & Life Sciences
X-Rays Medicine & Life Sciences

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Research Output 1969 2017

A Tunable Brake for HECT Ubiquitin Ligases

Chen, Z., Jiang, H., Xu, W., Li, X., Dempsey, D. R., Zhang, X., Devreotes, P., Wolberger, C., Amzel, L. M., Gabelli, S. B. & Cole, P. A. May 4 2017 In : Molecular Cell. 66, 3, p. 345-357.e6

Research output: Research - peer-reviewArticle

Ligases
Ubiquitin
Neoplasms
Ubiquitin-Protein Ligases
Immune System Diseases

Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design

Miller, M. S., Maheshwari, S., McRobb, F. M., Kinzler, K. W., Amzel, L. M., Vogelstein, B. & Gabelli, S. B. Feb 15 2017 In : Bioorganic and Medicinal Chemistry. 25, 4, p. 1481-1486 6 p.

Research output: Research - peer-reviewArticle

Phosphatidylinositol 3-Kinase
Allosteric Site
Binding Sites
X Ray Crystallography
Libraries

Kinetic and structural analyses reveal residues in phosphoinositide 3-kinase α that are critical for catalysis and substrate recognition

Maheshwari, S., Miller, M. S., O’Meally, R., Cole, R. N., Amzel, L. M. & Gabelli, S. B. 2017 In : Journal of Biological Chemistry. 292, 33, p. 13541-13550 10 p.

Research output: Research - peer-reviewArticle

Phosphatidylinositols
Catalysis
Phosphotransferases
Kinetics
Substrates

The Sodium/Iodide Symporter (NIS): Molecular Physiology and Preclinical and Clinical Applications

Ravera, S., Reyna-Neyra, A., Ferrandino, G., Amzel, L. M. & Carrasco, N. Feb 10 2017 In : Annual Review of Physiology. 79, p. 261-289 29 p.

Research output: Research - peer-reviewReview article

Symporters
sodium-iodide symporter
Thyroid Gland
Iodides
Diagnostic Imaging

Calmodulin and Ca2+ control of voltage gated Na+ channels

Gabelli, S. B., Yoder, J. B., Tomaselli, G. F. & Amzel, L. M. Jan 1 2016 In : Channels. 10, 1, p. 45-54 10 p.

Research output: Research - peer-reviewArticle

Sodium Channels
Calmodulin
Calcium
Electric potential
Mutation