Marikki Laiho

Professor

1985 …2018
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Research Output 1985 2018

Small-Molecule Targeting of RNA Polymerase I Activates a Conserved Transcription Elongation Checkpoint

Wei, T., Najmi, S. M., Liu, H., Peltonen, K., Kucerova, A., Schneider, D. A. & Laiho, M. Apr 10 2018 In : Cell Reports. 23, 2, p. 404-414 11 p.

Research output: Contribution to journalArticle

RNA Polymerase I
Efflorescence
Cracks
Response Elements
Enzymes

Novel assay to detect RNA polymerase I activity in vivo

Guner, G., Sirajuddin, P., Zheng, Q., Bai, B., Brodie, A., Liu, H., Af Hällström, T., Kulac, I., Laiho, M. & De Marzo, A. M. May 1 2017 In : Molecular Cancer Research. 15, 5, p. 577-584 8 p.

Research output: Contribution to journalArticle

RNA Polymerase I
Prostatic Intraepithelial Neoplasia
Prostate
RNA Precursors
Paraffin

Pharmacological inhibition of spinal cord injury-stimulated ribosomal biogenesis does not affect locomotor outcome

Kilanczyk, E., Andres, K. R., Hallgren, J., Ohri, S. S., Laiho, M., Whittemore, S. R. & Hetman, M. Mar 6 2017 In : Neuroscience Letters. 642, p. 153-157 5 p.

Research output: Contribution to journalArticle

Spinal Cord Injuries
Pharmacology
Wounds and Injuries
Endoplasmic Reticulum Stress
Oligodendroglia

Severe neurodegenerative disease in brothers with homozygous mutation in POLR1A

Kara, B., Köroǧlu, Ç., Peltonen, K., Steinberg, R. C., Maraş Genç, H., Hölttä-Vuori, M., Güven, A., Kanerva, K., Kotil, T., Solakoǧlu, S., Zhou, Y., Olkkonen, V. M., Ikonen, E., Laiho, M. & Tolun, A. Feb 1 2017 In : European Journal of Human Genetics. 25, 3, p. 315-323 9 p.

Research output: Contribution to journalArticle

Neurodegenerative Diseases
Siblings
Mutation
Mandibulofacial Dysostosis
RNA Polymerase I

Deep sequencing analysis of nucleolar small RNAs: Bioinformatics

Bai, B. & Laiho, M. 2016 Methods in Molecular Biology. Humana Press Inc., Vol. 1455, p. 243-248 6 p. (Methods in Molecular Biology; vol. 1455)

Research output: Chapter in Book/Report/Conference proceedingChapter

Small Nucleolar RNA
High-Throughput Nucleotide Sequencing
Computational Biology
RNA
Small Cytoplasmic RNA