Research Output 2004 2018

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Article
2018
Cyclooxygenase 2
Dextrans
Small Interfering RNA
Down-Regulation
Acids
2017

Breast cancer cell cyclooxygenase-2 expression alters extracellular matrix structure and function and numbers of cancer associated fibroblasts

Krishnamachary, B., Stasinopoulos, I., Kakkad, S., Penet, M. F., Jacob, D., Wildes, F., Mironchik, Y., Pathak, A. P., Solaiyappan, M. & Bhujwalla, Z. M. 2017 In : Oncotarget. 8, 11, p. 17981-17994 14 p.

Research output: Research - peer-reviewArticle

Cyclooxygenase 2
Extracellular Matrix
Breast Neoplasms
Cancer-Associated Fibroblasts
Neoplasms

Metabolomic characterization of experimental ovarian cancer ascitic fluid

Bharti, S. K., Wildes, F., Hung, C. F., Wu, T. C., Bhujwalla, Z. M. & Penet, M. F. Oct 1 2017 In : Metabolomics. 13, 10, 113

Research output: Research - peer-reviewArticle

Cells
Fluids
Metabolomics
Ascitic Fluid
Ascites
Extracellular Matrix
Prostatic Neoplasms
Neoplasms
Collagen
Albumins
2016

Detection of pancreatic cancer-induced cachexia using a fluorescent myoblast reporter system and analysis of metabolite abundance

Winnard, P. T., Bharti, S. K., Penet, M. F., Marik, R., Mironchik, Y., Wildes, F., Maitra, A. & Bhujwalla, Z. M. Mar 15 2016 In : Cancer Research. 76, 6, p. 1441-1450 10 p.

Research output: Research - peer-reviewArticle

Cachexia
Myoblasts
Systems Analysis
Pancreatic Neoplasms
Weight Loss

Effect of Pantethine on Ovarian Tumor Progression and Choline Metabolism

Penet, M. F., Krishnamachary, B., Wildes, F., Mironchik, Y., Mezzanzanica, D., Podo, F., De Reggi, M., Gharib, B. & Bhujwalla, Z. M. Nov 16 2016 In : Frontiers in Oncology. 6, NOV, 244

Research output: Research - peer-reviewArticle

Choline
Neoplasms
pantethine
Therapeutics
Ovarian Neoplasms

Magnetic Resonance Imaging and Spectroscopy in Cancer Theranostic Imaging

Penet, M. F., Jin, J., Chen, Z. & Bhujwalla, Z. M. Jun 29 2016 (Accepted/In press) In : Topics in Magnetic Resonance Imaging.

Research output: Research - peer-reviewArticle

Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
Neoplasms
Therapeutics
Theranostic Nanomedicine

Microglia activation in a pediatric rabbit model of tuberculous meningitis

Tucker, E. W., Pokkali, S., Zhang, Z., DeMarco, V. P., Klunk, M., Smith, E. S., Ordonez, A. A., Penet, M. F., Bhujwalla, Z., Jain, S. K. & Kannan, S. Dec 1 2016 In : DMM Disease Models and Mechanisms. 9, 12, p. 1497-1502 6 p.

Research output: Research - peer-reviewArticle

Meningeal Tuberculosis
Microglia
Pediatrics
Rabbits
Chemical activation
Flucytosine
Prodrugs
Prostatic Neoplasms
Tumor Necrosis Factor-alpha
Apoptosis
2015

Cancer cachexia, recent advances, and future directions

Penet, M. F. & Bhujwalla, Z. M. Mar 9 2015 In : Cancer Journal (United States). 21, 2, p. 117-122 6 p.

Research output: Research - peer-reviewArticle

Cachexia
Neoplasms
Direction compound
Molecular Imaging
Nutritional Support
Choline
Neoplasms
Choline Kinase
Magnetic Resonance Spectroscopy
Therapeutics

Metabolic imaging of pancreatic ductal adenocarcinoma detects altered choline metabolism

Penet, M. F., Shah, T., Bharti, S., Krishnamachary, B., Artemov, D., Mironchik, Y., Wildes, F., Maitra, A. & Bhujwalla, Z. M. Jan 15 2015 In : Clinical Cancer Research. 21, 2, p. 386-395 10 p.

Research output: Research - peer-reviewArticle

Choline
Adenocarcinoma
choline transporter
Biomarkers
Choline Kinase
2014

A biomimetic collagen derived peptide exhibits anti- Angiogenic activity in triple negative breast cancer

Rosca, E. V., Penet, M. F., Mori, N., Koskimaki, J. E., Lee, E., Pandey, N. B., Bhujwalla, Z. M. & Popel, A. S. Nov 10 2014 In : PLoS One. 9, 11, e111901

Research output: Research - peer-reviewArticle

Triple Negative Breast Neoplasms
Biomimetics
Collagen
Peptides
biomimetics
Precision Medicine
Molecular Imaging
Tumor Microenvironment
Neoplasms
Theranostic Nanomedicine
2013

COX-2 in cancer: Gordian knot or achilles heel?

Stasinopoulos, I., Shah, T., Penet, M. F., Krishnamachary, B. & Bhujwalla, Z. M. 2013 In : Frontiers in Pharmacology. 4 MAR, Article 34

Research output: Research - peer-reviewArticle

Cyclooxygenase 2
Neoplasms
Neoplasm Metastasis
Lymphatic Vessels
Tumor Microenvironment
Collagen
Neoplasms
collagen
neoplasms
Tumors

MR - Eyes For Cancer: Looking Within An Impenetrable Disease

Penet, M. F., Artemov, D., Farahani, K. & Bhujwalla, Z. M. Jul 2013 In : NMR in Biomedicine. 26, 7, p. 745-755 11 p.

Research output: Research - peer-reviewArticle

Eye Neoplasms
Neoplasms
Imaging techniques
Molecular Probes
Molecular Imaging
2012
breast neoplasms
hypoxia
Protein Isoforms
Cells
Triple Negative Breast Neoplasms
Prodrugs
Enzymes
Neoplasms
Therapeutics
Cytotoxins
antigens
therapy
cancer
membranes
Antigens

The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway

Jin, K., Kong, X., Shah, T., Penet, M. F., Wildes, F., Sgroi, D. C., Ma, X. J., Huang, Y., Kallioniemi, A., Landberg, G., Bieche, I., Wu, X., Lobie, P. E., Davidson, N. E., Bhujwalla, Z. M., Zhu, T. & Sukumar, S. Feb 21 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 8, p. 2736-2741 6 p.

Research output: Research - peer-reviewArticle

Tamoxifen
Breast Neoplasms
Proteins
MCF-7 Cells
Therapeutics

Theranostic imaging of cancer

Penet, M. F., Chen, Z., Kakkad, S., Pomper, M. G. & Bhujwalla, Z. M. Sep 2012 In : European Journal of Radiology. 81, SUPPL1

Research output: Research - peer-reviewArticle

Molecular Targeted Therapy
Tumor Microenvironment
Molecular Pathology
Diagnostic Imaging
Antineoplastic Agents
2011

Exploiting the tumor microenvironment for theranostic imaging

Stasinopoulos, I., Penet, M. F., Chen, Z., Kakkad, S., Glunde, K. & Bhujwalla, Z. M. Jul 2011 In : NMR in Biomedicine. 24, 6, p. 636-647 12 p.

Research output: Research - peer-reviewArticle

Tumor Microenvironment
Neoplasms
Theranostic Nanomedicine
Tumors
Imaging techniques

Metabolic signatures imaged in cancer-induced cachexia

Penet, M. F., Gadiya, M. M., Krishnamachary, B., Nimmagadda, S., Pomper, M. G., Artemov, D. & Bhujwalla, Z. M. Nov 15 2011 In : Cancer Research. 71, 22, p. 6948-6956 9 p.

Research output: Research - peer-reviewArticle

Cachexia
Neoplasms
Choline
Therapeutics
Weight Loss

MRI of metastasis-permissive microenvironments

Penet, M. F., Chen, Z. & Bhujwalla, Z. M. Nov 2011 In : Future Oncology. 7, 11, p. 1269-1284 16 p.

Research output: Research - peer-reviewArticle

Neoplasm Metastasis
Neoplasms
Tumor Microenvironment
Molecular Imaging
Molecular Biology
Cachexia
Neoplasms
Molecular Imaging
Lipid Metabolism
Fatigue
2010

Applications of molecular MRI and optical imaging in cancer

Penet, M. F., Mikhaylova, M., Li, C., Krishnamachary, B., Glunde, K., Pathak, A. P. & Bhujwalla, Z. M. Jun 2010 In : Future Medicinal Chemistry. 2, 6, p. 975-988 14 p.

Research output: Research - peer-reviewArticle

Molecular Imaging
Optical Imaging
Neoplasms
Pharmaceutical Preparations
Nanoparticles
Choline Kinase
Cells
Pharmaceutical Preparations
Drug Resistance
Breast Neoplasms
Magnetic resonance spectroscopy
Molecular imaging
Magic angle spinning
Molecular biology
Biopsy

Molecular and functional imaging of invasion and metastasis: Windows into the metastatic cascade

Stasinopoulos, I., Penet, M. F., Krishnamachary, B. & Bhujwalla, Z. M. 2010 In : Cancer Biomarkers. 7, 4-5, p. 173-188 16 p.

Research output: Research - peer-reviewArticle

Molecular Imaging
Neoplasm Metastasis
Neoplasms
Cellular Microenvironment
Tumor Microenvironment

Nanoplex delivery of siRNA and prodrug enzyme for multimodality image-guided molecular pathway targeted cancer therapy

Li, C., Penet, M. F., Wildes, F., Takagi, T., Chen, Z., Winnard, P. T., Artemov, D. & Bhujwalla, Z. M. Nov 23 2010 In : ACS Nano. 4, 11, p. 6707-6716 10 p.

Research output: Research - peer-reviewArticle

Prodrugs
Small Interfering RNA
Enzymes
enzymes
therapy
2009
Heterografts
Prostatic Neoplasms
Neoplasm Metastasis
Hypoxia
Neoplasms
2008
Cytosine Deaminase
Prodrugs
Lysine
Enzymes
Neoplasms

Image-guided enzyme/prodrug cancer therapy

Li, C., Penet, M. F., Winnard, P., Artemov, D. & Bhujwalla, Z. M. Jan 15 2008 In : Clinical Cancer Research. 14, 2, p. 515-522 8 p.

Research output: Research - peer-reviewArticle

Prodrugs
Enzymes
Neoplasms
Therapeutics
Optical Imaging

Molecular and functional MRI of the tumor microenvironment

Penet, M. F., Glunde, K., Jacobs, M. A., Pathak, A. P. & Bhujwalla, Z. M. May 1 2008 In : Journal of Nuclear Medicine. 49, 5, p. 687-690 4 p.

Research output: Research - peer-reviewArticle

Tumor Microenvironment
Extracellular Matrix
Magnetic Resonance Imaging
Neoplasms
Hypoxia

Protection against cerebral malaria by the low-molecular-weight thiol pantethine

Penet, M. F., Abou-Hamdan, M., Coltel, N., Cornille, E., Grau, G. E., De Reggi, M. & Gharib, B. Jan 29 2008 In : Proceedings of the National Academy of Sciences of the United States of America. 105, 4, p. 1321-1326 6 p.

Research output: Research - peer-reviewArticle

Cerebral Malaria
Sulfhydryl Compounds
Molecular Weight
pantethine
Therapeutics
2007

Magnetic resonance spectroscopy reveals an impaired brain metabolic profile in mice resistant to cerebral malaria infected with Plasmodium berghei ANKA

Penet, M. F., Kober, F., Confort-Gouny, S., Le Fur, Y., Dalmasso, C., Coltel, N., Liprandi, A., Gulian, J. M., Grau, G. E., Cozzone, P. J. & Viola, A. May 11 2007 In : Journal of Biological Chemistry. 282, 19, p. 14505-14514 10 p.

Research output: Research - peer-reviewArticle

Cerebral Malaria
Plasmodium berghei
Metabolome
Magnetic Resonance Spectroscopy
Brain
2006

In vivo characterization of brain morphometric and metabolic endophenotypes in three inbred strains of mice using magnetic resonance techniques

Penet, M. F., Laigle, C., Fur, Y. L., Confort-Gouny, S., Heurteaux, C., Cozzone, P. J. & Viola, A. Sep 2006 In : Behavior Genetics. 36, 5, p. 732-744 13 p.

Research output: Research - peer-reviewArticle

129 Strain Mouse
Endophenotypes
Neuroanatomy
Inbred Strains Mice
Psychiatry
2005

Imaging experimental cerebral malaria in vivo: Significant role of ischemic brain edema

Penet, M. F., Viola, A., Confort-Gouny, S., Le Fur, Y., Duhamel, G., Kober, F., Ibarrola, D., Izquierdo, M., Coltel, N., Gharib, B., Grau, G. E. & Cozzone, P. J. Aug 10 2005 In : Journal of Neuroscience. 25, 32, p. 7352-7358 7 p.

Research output: Research - peer-reviewArticle

Cerebral Malaria
Brain Edema
Edema
Brain
Blood-Brain Barrier
2004

Vanin-1-/- mice show decreased NSAID- and Schistosoma-induced intestinal inflammation associated with higher gluthathione stores

Martin, F., Penet, M. F., Malergue, F., Lepidi, H., Dessein, A., Galland, F., De Reggi, M., Naquet, P. & Gharib, B. Feb 2004 In : Journal of Clinical Investigation. 113, 4, p. 591-597 7 p.

Research output: Research - peer-reviewArticle

Schistosoma
Cysteamine
Non-Steroidal Anti-Inflammatory Agents
Glutathione
Inflammation