Malia Edwards

Assistant Professor

20062020

Research output per year

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Research Output

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Albumen transport to bruch’s membrane and RPE by choriocapillaris caveolae

Nakanishi, M., Grebe, R., Bhutto, I. A., Edwards, M., Scott Mcleod, D. & Lutty, G. A., Apr 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 4, p. 2213-2224 12 p.

Research output: Contribution to journalArticle

An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy

Bhutto, I. A., Ogura, S., Baldeosingh, R., McLeod, D. S., Lutty, G. A. & Edwards, M. M., Mar 20 2018, In : Investigative ophthalmology & visual science. 59, 4, p. AMD143-AMD151

Research output: Contribution to journalArticle

Choriocapillaris dropout in early age-related macular degeneration

Lutty, G. A., McLeod, D. S., Bhutto, I. A., Edwards, M. M. & Seddon, J. M., Mar 2020, In : Experimental eye research. 192, 107939.

Research output: Contribution to journalArticle

Defective angiogenesis and intraretinal bleeding in mouse models with disrupted inner retinal lamination

Simmons, A. B., Merrill, M. M., Reed, J. C., Deans, M. R., Edwards, M. M. & Fuerst, P. G., Apr 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 4, p. 1563-1577 15 p.

Research output: Contribution to journalArticle

Distribution and quantification of choroidal macrophages in human eyes with age-related macular degeneration

McLeod, D. S., Bhutto, I., Edwards, M., Silver, R. E., Seddon, J. M. & Lutty, G. A., Nov 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 14, p. 5843-5855 13 p.

Research output: Contribution to journalArticle

From blood islands to blood vessels: Morphologic observations and expression of key molecules during hyaloid vascular system development

Scott Mcleod, D., Hasegawa, T., Baba, T., Grebe, R., d'Auriac, I. G., Merges, C., Edwards, M. & Lutty, G. A., Dec 1 2012, In : Investigative Ophthalmology and Visual Science. 53, 13, p. 7912-7927 16 p.

Research output: Contribution to journalArticle

Functional role of laminin α1 chain during cerebellum development

Heng, C., Lefebvre, O., Klein, A., Edwards, M. M., Simon-Assmann, P., Orend, G. & Bagnard, D., Jan 1 2011, In : Cell Adhesion and Migration. 5, 6, p. 480-489 10 p.

Research output: Contribution to journalArticle

Histopathological insights into choroidal vascular loss in clinically documented cases of age-related macular degeneration

Seddon, J. M., McLeod, D. S., Bhutto, I. A., Villalonga, M. B., Silver, R. E., Wenick, A., Edwards, M. & Lutty, G. A., Nov 1 2016, In : JAMA Ophthalmology. 134, 11, p. 1272-1280 9 p.

Research output: Contribution to journalArticle

Idiopathic preretinal glia in aging and age-related macular degeneration

Edwards, M. M., McLeod, D. S., Bhutto, I. A., Villalonga, M. B., Seddon, J. M. & Lutty, G. A., Sep 1 2016, In : Experimental eye research. 150, p. 44-61 18 p.

Research output: Contribution to journalArticle

Increased Lipocalin-2 in the retinal pigment epithelium of Cryba1 cKO mice is associated with a chronic inflammatory response

Valapala, M., Edwards, M., Hose, S., Grebe, R., Bhutto, I. A., Cano, M., Berger, T., Mak, T. W., Wawrousek, E., Handa, J. T., Lutty, G. A., Samuel Zigler, J. & Sinha, D., Dec 1 2014, In : Aging Cell. 13, 6, p. 1091-1094 4 p.

Research output: Contribution to journalArticle

Lama1 mutations lead to vitreoretinal blood vessel formation, persistence of fetal vasculature, and epiretinal membrane formation in mice

Edwards, M. M., McLeod, D. S., Grebe, R., Heng, C., Lefebvre, O. & Lutty, G. A., Oct 17 2011, In : BMC Developmental Biology. 11, 60.

Research output: Contribution to journalArticle

Mast cell-derived tryptase in geographic atrophy

McLeod, D. S., Bhutto, I., Edwards, M., Gedam, M., Baldeosingh, R. & Lutty, G. A., Nov 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 13, p. 5887-5896 10 p.

Research output: Contribution to journalArticle

Mutations in Lama1 disrupt retinal vascular development and inner limiting membrane formation

Edwards, M. M., Mammadova-Bach, E., Alpy, F., Klein, A., Hicks, W. L., Roux, M., Simon-Assmann, P., Smith, R. S., Orend, G., Wu, J., Peachey, N. S., Naggert, J. K., Lefebvre, O. & Nishina, P. M., Mar 5 2010, In : Journal of Biological Chemistry. 285, 10, p. 7697-7711 15 p.

Research output: Contribution to journalArticle

Mutations of the opsin gene (Y102H and I307N) lead to light-induced degeneration of photoreceptors and constitutive activation of phototransduction in mice

Budzynski, E., Gross, A. K., McAlear, S. D., Peachey, N. S., Shukla, M., He, F., Edwards, M., Won, J., Hicks, W. L., Wensel, T. G., Naggert, J. K. & Nishina, P. M., May 7 2010, In : Journal of Biological Chemistry. 285, 19, p. 14521-14533 13 p.

Research output: Contribution to journalArticle

NPHP4 is necessary for normal photoreceptor ribbon synapse maintenance and outer segment formation, and for sperm development

Won, J., de Evsikova, C. M., Smith, R. S., Hicks, W. L., Edwards, M. M., Longo-Guess, C., Li, T., Naggert, J. K. & Nishina, P. M., Feb 1 2011, In : Human molecular genetics. 20, 3, p. 482-496 15 p., ddq494.

Research output: Contribution to journalArticle

Ocular Histopathology and Immunohistochemical Analysis in the Oldest Known Individual with Autosomal Dominant Vitreoretinochoroidopathy

Goldberg, M. F., McLeod, S., Tso, M., Packo, K., Edwards, M., Bhutto, I. A., Baldeosingh, R., Eberhart, C., Weber, B. H. F. & Lutty, G. A., Apr 1 2018, In : Ophthalmology Retina. 2, 4, p. 360-378 19 p.

Research output: Contribution to journalArticle

Photoreceptor Degeneration, Azoospermia, Leukoencephalopathy, And Abnormal RPE Cell Function In Mice Expressing An Early Stop Mutation In CLCN2

Edwards, M. M., de Evsikova, C. M., Collin, G. B., Gifford, E., Wu, J., Hicks, W. L., Whiting, C., Varvel, N. H., Lamb, B. T., Maphis, N., Naggert, J. K., Nishina, P. M. & Peachey, N. S., Jun 1 2010, In : Investigative Ophthalmology and Visual Science. 51, 6, p. 3264-3272 9 p.

Research output: Contribution to journalArticle

Retinal macroglia changes in a triple transgenic mouse model of Alzheimer's disease

Edwards, M. M., Rodríguez, J. J., Gutierrez-Lanza, R., Yates, J., Verkhratsky, A. & Lutty, G. A., Oct 2014, In : Experimental eye research. 127, p. 252-260 9 p.

Research output: Contribution to journalArticle

Subretinal glial membranes in eyes with geographic atrophy

Edwards, M., McLeod, D. S., Bhutto, I. A., Grebe, R., Duffy, M. & Lutty, G. A., Mar 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 3, p. 1352-1367 16 p.

Research output: Contribution to journalArticle

Systemic and intravitreal delivery of dendrimers to activated microglia/macrophage in ischemia/reperfusion mouse retina

Kambhampati, S. P., Clunies-Ross, A. J. M., Bhutto, I., Mishra, M. K., Edwards, M., McLeod, D. S., Kannan, R. M. & Lutty, G., Jan 1 2015, In : Investigative Ophthalmology and Visual Science. 56, 8, p. 4413-4424 12 p.

Research output: Contribution to journalArticle

The deletion of Math5 disrupts retinal blood vessel and glial development in mice

Edwards, M. M., McLeod, D. S., Li, R., Grebe, R., Bhutto, I., Mu, X. & Lutty, G. A., Mar 1 2012, In : Experimental eye research. 96, 1, p. 147-156 10 p.

Research output: Contribution to journalArticle

TNF alpha affects the expression of GFAP and S100B: Implications for Alzheimer's disease

Edwards, M. M. & Robinson, S. R., Nov 1 2006, In : Journal of Neural Transmission. 113, 11, p. 1709-1715 7 p.

Research output: Contribution to journalArticle

Ultrastructural analysis of submacular choriocapillaris and its transport systems in AMD and aged control eyes

Grebe, R., Mughal, I., Bryden, W., McLeod, S., Edwards, M., Hageman, G. S. & Lutty, G. A., Apr 1 2019, In : Experimental eye research. 181, p. 252-262 11 p.

Research output: Contribution to journalArticle

VEGF 165b in the developing vasculatures of the fetal human eye

Baba, T., Mcleod, D. S., Edwards, M. M., Merges, C., Sen, T., Sinha, D. & Lutty, G. A., Mar 1 2012, In : Developmental Dynamics. 241, 3, p. 595-607 13 p.

Research output: Contribution to journalArticle

βa3/A1-crystallin is a critical mediator of STAT3 signaling in optic nerve astrocytes

Valapala, M., Edwards, M., Hose, S., Hu, J., Wawrousek, E., Lutty, G. A., Zigler, J. S., Qian, J. & Sinha, D., Jan 1 2015, In : Scientific reports. 5, 8755.

Research output: Contribution to journalArticle