Mali Jiang

Research Associate

20022018
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Fingerprint Dive into the research topics where Mali Jiang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Huntington Disease Medicine & Life Sciences
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Tetanus Medicine & Life Sciences
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Research Output 2002 2018

Small molecule modulator of protein disulfide isomerase attenuates mutant huntingtin toxicity and inhibits endoplasmic reticulum stress in a mouse model of Huntington's disease

Zhou, X., Li, G., Kaplan, A., Gaschler, M. M., Zhang, X., Hou, Z., Jiang, M., Zott, R., Cremers, S., Stockwell, B. R. & Duan, W., May 1 2018, In : Human Molecular Genetics. 27, 9, p. 1545-1555 11 p.

Research output: Contribution to journalArticle

Protein Disulfide-Isomerases
Endoplasmic Reticulum Stress
Huntington Disease
Brain
Endoplasmic Reticulum

2,4 DNP improves motor function, preserves medium spiny neuronal identity, and reduces oxidative stress in a mouse model of Huntington's disease

Wu, B., Jiang, M., Peng, Q., Li, G., Hou, Z., Milne, G. L., Mori, S., Alonso, R., Geisler, J. G. & Duan, W., Jul 1 2017, In : Experimental Neurology. 293, p. 83-90 8 p.

Research output: Contribution to journalArticle

2,4-Dinitrophenol
Huntington Disease
Oxidative Stress
Proton Ionophores
F2-Isoprostanes

Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats

Ratovitski, T., O'Meally, R. N., Jiang, M., Chaerkady, R., Chighladze, E., Stewart, J. C., Wang, X., Arbez, N., Roby, E., Alexandris, A., Duan, W., Vijayvargia, R., Seong, I. S., Lavery, D. J., Cole, R. N. & Ross, C. A., Aug 4 2017, In : Journal of Proteome Research. 16, 8, p. 2692-2708 17 p.

Research output: Contribution to journalArticle

Post Translational Protein Processing
Mass spectrometry
Huntington Disease
Brain
Phospho-Specific Antibodies

Characterization of behavioral, neuropathological, brain metabolic and key molecular changes in zQ175 knock-in mouse model of huntington's disease

Peng, Q., Wu, B., Jiang, M., Jin, J., Hou, Z., Zheng, J., Zhang, J. & Duan, W., Feb 1 2016, In : PLoS One. 11, 2, e0148839.

Research output: Contribution to journalArticle

Huntington Disease
Brain
animal models
brain
mice

Metformin Protects Cells from Mutant Huntingtin Toxicity Through Activation of AMPK and Modulation of Mitochondrial Dynamics

Jin, J., Gu, H., Anders, N., Ren, T., Jiang, M., Tao, M., Peng, Q., Rudek-Renaut, M. & Duan, W., May 25 2016, (Accepted/In press) In : NeuroMolecular Medicine. p. 1-12 12 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
AMP-Activated Protein Kinases
Metformin
Huntington Disease
Caloric Restriction