Lynda D Hester

Research Associate

1977 …2019

Research output per year

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Research Output

2019

Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide

Vasavda, C., Kothari, R., Malla, A. P., Tokhunts, R., Lin, A., Ji, M., Ricco, C., Xu, R., Saavedra, H. G., Sbodio, J. I., Snowman, A. M., Albacarys, L., Hester, L. D., Sedlak, T. W., Paul, B. & Snyder, S. H., Oct 17 2019, In : Cell Chemical Biology. 26, 10, p. 1450-1460.e7

Research output: Contribution to journalArticle

2013

Towards Neuronal Organoids: A Method for Long-Term Culturing of High-Density Hippocampal Neurons

Todd, G. K., Boosalis, C. A., Burzycki, A. A., Steinman, M. Q., Hester, L. D., Shuster, P. W. & Patterson, R. L., Apr 25 2013, In : PloS one. 8, 4, e58996.

Research output: Contribution to journalArticle

2011

Glutathione is a physiologic reservoir of neuronal glutamate

Koga, M., Serritella, A. V., Messmer, M. M., Hayashi-Takagi, A., Hester, L. D., Snyder, S. H., Sawa, A. & Sedlak, T. W., Jun 17 2011, In : Biochemical and Biophysical Research Communications. 409, 4, p. 596-602 7 p.

Research output: Contribution to journalArticle

S-Nitrosylation and S-Palmitoylation Reciprocally Regulate Synaptic Targeting of PSD-95

Ho, G. P. H., Selvakumar, B., Mukai, J., Hester, L. D., Wang, Y., Gogos, J. A. & Snyder, S. H., Jul 14 2011, In : Neuron. 71, 1, p. 131-141 11 p.

Research output: Contribution to journalArticle

2010

Death-associated protein kinase-mediated cell death modulated by interaction with DANGER

Kang, B. N., Ahmad, A. S., Saleem, S., Patterson, R. L., Hester, L., Doré, S. & Snyder, S. H., Jan 6 2010, In : Journal of Neuroscience. 30, 1, p. 93-98 6 p.

Research output: Contribution to journalArticle

GAPDH mediates nitrosylation of nuclear proteins

Kornberg, M. D., Sen, N., Hara, M. R., Juluri, K. R., Nguyen, J. V. K., Snowman, A. M., Law, L., Hester, L. D. & Snyder, S. H., Nov 1 2010, In : Nature cell biology. 12, 11, p. 1094-1100 7 p.

Research output: Contribution to journalArticle

2009

GOSPEL: A Neuroprotective Protein that Binds to GAPDH upon S-Nitrosylation (DOI:10.1016/j.neuron.2009.05.024)

Sen, N., Hara, M. R., Ahmad, A. S., Cascio, M. B., Kamiya, A., Ehmsen, J. T., Agrawal, N., Hester, L., Doré, S., Snyder, S. H. & Sawa, A., Sep 10 2009, In : Neuron. 63, 5, 1 p.

Research output: Contribution to journalComment/debate

GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylation.

Sen, N., Hara, M. R., Ahmad, A. S., Cascio, M. B., Kamiya, A., Ehmsen, J. T., Aggrawal, N., Hester, L., Doré, S., Snyder, S. H. & Sawa, A., Jul 16 2009, In : Neuron. 63, 1, p. 81-91 11 p.

Research output: Contribution to journalArticle

2008
2007

Neuronal growth and survival mediated by eIF5A, a polyamine-modified translation initiation factor

Huang, Y., Higginson, D. S., Hester, L., Myung, H. P. & Snyder, S. H., Mar 6 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 10, p. 4194-4199 6 p.

Research output: Contribution to journalArticle

2006

Neuroprotection by pharmacologic blockade of the GAPDH death cascade

Hara, M. R., Thomas, B., Cascio, M. B., Bae, B. I., Hester, L. D., Dawson, V. L., Dawson, T. M., Sawa, A. & Snyder, S. H., Mar 7 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 10, p. 3887-3889 3 p.

Research output: Contribution to journalArticle

NMDA Receptor-Nitric Oxide Transmission Mediates Neuronal Iron Homeostasis via the GTPase Dexras1

Cheah, J. H., Kim, S. F., Hester, L. D., Clancy, K. W., Patterson, S. E., Papadopoulos, V. & Snyder, S. H., Aug 17 2006, In : Neuron. 51, 4, p. 431-440 10 p.

Research output: Contribution to journalArticle

2005

S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding

Hara, M. R., Agrawal, N., Kim, S. F., Cascio, M. B., Fujimuro, M., Ozeki, Y., Takahashi, M., Cheah, J. H., Tankou, S. K., Hester, L. D., Ferris, C. D., Hayward, S. D., Snyder, S. H. & Sawa, A., Jul 1 2005, In : Nature cell biology. 7, 7, p. 665-674 10 p.

Research output: Contribution to journalArticle

2003

Akt as a mediator of cell death

Luo, H. R., Hattori, H., Hossain, M. A., Hester, L., Huang, Y., Lee-Kwon, W., Donowitz, M., Nagata, E. & Snyder, S. H., Sep 30 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 20, p. 11712-11717 6 p.

Research output: Contribution to journalArticle

Carbon monoxide neurotransmission activated by CK2 phosphorylation of heme oxygenase-2

Boehning, D., Moon, C., Sharma, S., Hurt, K. J., Hester, L. D., Ronnett, G. V., Shugar, D. & Snyder, S. H., Sep 25 2003, In : Neuron. 40, 1, p. 129-137 9 p.

Research output: Contribution to journalArticle

2002
2000

Heme oxygenase-2 acts to prevent neuronal death in brain cultures and following transient cerebral ischemia

Doré, S., Goto, S., Sampei, K., Blackshaw, S., Hester, L. D., Ingi, T., Sawa, A., Traystman, R. J., Koehler, R. C. & Snyder, S. H., Aug 23 2000, In : Neuroscience. 99, 4, p. 587-592 6 p.

Research output: Contribution to journalArticle

1999

Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury

Doré, S., Takahashi, M., Ferris, C. D., Hester, L. D., Guastella, D. & Snyder, S. H., Mar 2 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 5, p. 2445-2450 6 p.

Research output: Contribution to journalArticle

1997

Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A

Steiner, J. P., Connolly, M. A., Valentine, H. L., Hamilton, G. S., Dawson, T. M., Hester, L. & Snyder, S. H., Apr 15 1997, In : Nature medicine. 3, 4, p. 421-428 8 p.

Research output: Contribution to journalArticle

1996
Open Access
1994

Human cerebral cortical cell lines from patients with unilateral megalencephaly and Rasmussen's encephalitis

Ronnett, G. V., Hester, L. D., Nye, J. S. & Snyder, S. H., Dec 1994, In : Neuroscience. 63, 4, p. 1081-1099 19 p.

Research output: Contribution to journalArticle

1993

Odorants differentially enhance phosphoinositide turnover and adenylyl cyclase in olfactory receptor neuronal cultures

Ronnett, G. V., Cho, H., Hester, L. D., Wood, S. F. & Snyder, S. H., Jan 1 1993, In : Journal of Neuroscience. 13, 4, p. 1751-1758 8 p.

Research output: Contribution to journalArticle

1991
Open Access

Primary culture of neonatal rat olfactory neurons

Ronnett, G. V., Hester, L. D. & Snyder, S. H., Jan 1 1991, In : Journal of Neuroscience. 11, 5, p. 1243-1255 13 p.

Research output: Contribution to journalArticle

1990

Human cortical neuronal cell line: Establishment from a patient with unilateral megalencephaly

Ronnett, G. V., Hester, L. D., Nye, J. S., Connors, K. & Snyder, S. H., Jan 1 1990, In : Science. 248, 4955, p. 603-605 3 p.

Research output: Contribution to journalArticle

1988

Phenylalkylamine-sensitive calcium channels in osteoblast-like osteosarcoma cells. Characterization by ligand binding and single channel recordings

Guggino, S. E., Wagner, J. A., Snowman, A. M., Hester, L. D., Sacktor, B. & Snyder, S. H., Jan 1 1988, In : Journal of Biological Chemistry. 263, 21, p. 10155-10161 7 p.

Research output: Contribution to journalArticle

1984

Monoclonal antibody production by receptor-mediated electrically induced cell fusion

Lo, M. M. S., Tsong, T. Y., Conrad, M. K., Strittmatter, S. M., Hester, L. D. & Snyder, S. H., Dec 1 1984, In : Nature. 310, 5980, p. 792-794 3 p.

Research output: Contribution to journalArticle

1983

Adenosine receptors: Autoradiographic evidence for their location on axon terminals of excitatory neurons

Goodman, R. R., Kuhar, M. J., Hester, L. & Snyder, S. H., Jan 1 1983, In : Science. 220, 4600, p. 967-969 3 p.

Research output: Contribution to journalArticle

1981

Diffuse enkephalin innervation from caudate to globus pallidus

Correa, F. M. A., Innis, R. B., Hester, L. D. & Snyder, S. H., Aug 7 1981, In : Neuroscience Letters. 25, 1, p. 63-68 6 p.

Research output: Contribution to journalArticle

1977

Temporal Acquisition of Enhanced Fibrinolytic Activity by Syrian Hamster Embryo Cells following Treatment with Benzo(a)pyrene

Jones, P. A., Benedict, W. F., Grady, D. L. & Hester, L. D., Oct 1977, In : Cancer Research. 37, 10, p. 3815-3823 9 p.

Research output: Contribution to journalArticle