Lukasz Gondek

Assistant Professor

20052020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
Article

250K single nucleotide polymorphism array karyotyping identifies acquired uniparental disomy and homozygous mutations, including novel missense substitutions of c-Cbl, in myeloid malignancies

Dunbar, A. J., Gondek, L. P., O'Keefe, C. L., Makishima, H., Rataul, M. S., Szpurka, H., Sekeres, M. A., Xiao, F. W., McDevitt, M. A. & Maciejewski, J. P., Dec 15 2008, In : Cancer Research. 68, 24, p. 10349-10357 9 p.

Research output: Contribution to journalArticle

Aberrant DNA methylation is a dominant mechanism in MDS progression to AML

Jiang, Y., Dunbar, A., Gondek, L. P., Mohan, S., Rataul, M., O'Keefe, C., Sekeres, M., Saunthararajah, Y. & Maciejewski, J. P., Feb 5 2009, In : Blood. 113, 6, p. 1315-1325 11 p.

Research output: Contribution to journalArticle

Anthracycline-induced acute myocarditis and ventricular fibrillation arrest

Pallazola, V. A., Murray, J. C., Al Harthy, M., Zimmerman, S., Webster, J. & Gondek, L., Jan 1 2017, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

Base excision repair dysfunction in a subgroup of patients with myelodysplastic syndrome

Jankowska, A. M., Gondek, L. P., Szpurka, H., Nearman, Z. P., Tiu, R. V. & Maciejewski, J. P., Mar 2008, In : Leukemia. 22, 3, p. 551-558 8 p.

Research output: Contribution to journalArticle

Characterization of chromosome arm 20q abnormalities in myeloid malignancies using genome-wide single nucleotide polymorphism array analysis

Huh, J., Tiu, R. V., Gondek, L. P., O'Keefe, C. L., Jasek, M., Makishima, H., Jankowska, A. M., Jiang, Y., Verma, A., Theil, K. S., McDevitt, M. A. & Maciejewski, J. P., Apr 1 2010, In : Genes Chromosomes and Cancer. 49, 4, p. 390-399 10 p.

Research output: Contribution to journalArticle

Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML

Gondek, L. P., Tiu, R., O'Keefe, C. L., Sekeres, M. A., Theil, K. S. & Maciejewski, J. P., Feb 12 2008, In : Blood. 111, 3, p. 1534-1542 9 p.

Research output: Contribution to journalArticle

Clonal hematopoiesis in Philadelphia chromosome-negative bone marrow cells of chronic myeloid leukemia patients receiving dasatinib

Paquette, R. L., Nicoll, J., Chalukya, M., Gondek, L., Jasek, M., Sawyers, C. L., Shah, N. P. & Maciejewski, J., Jun 1 2010, In : Leukemia Research. 34, 6, p. 708-713 6 p.

Research output: Contribution to journalArticle

Clonotype analysis of cytomegalovirus-specific cytotoxic T lymphocytes

Babel, N., Brestrich, G., Gondek, L. P., Sattler, A., Wlodarski, M. W., Poliak, N., Bethke, N., Thiel, A., Hammer, M. H., Reinke, P. & Maciejewski, J. P., Feb 1 2009, In : Journal of the American Society of Nephrology. 20, 2, p. 344-352 9 p.

Research output: Contribution to journalArticle

Detection of cryptic chromosomal lesions including acquired segmental uniparental disomy in advanced and low-risk myelodysplastic syndromes

Gondek, L. P., Haddad, A. S., O'Keefe, C. L., Tiu, R., Wlodarski, M. W., Sekeres, M. A., Theil, K. S. & Maciejewski, J. P., Nov 1 2007, In : Experimental Hematology. 35, 11, p. 1728-1738 11 p.

Research output: Contribution to journalArticle

Donor cell leukemia arising from clonal hematopoiesis after bone marrow transplantation

Gondek, L., Zheng, G., Ghiaur, G., Dezern, A., Matsui, W., Yegnasubramanian, S., Lin, M-T., Levis, M. J., Eshleman, J., Varadhan, R., Tucker, N., Jones, R. J. & Gocke, C., Mar 15 2016, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Efficient identification of T-cell clones associated with graft-versus-host disease in target tissue allows for subsequent detection in peripheral blood

Beck, R. C., Wlodarski, M., Gondek, L., Theil, K. S., Tuthill, R. J., Sobeck, R., Bolwell, B. & Maciejewski, J. P., May 1 2005, In : British journal of haematology. 129, 3, p. 411-419 9 p.

Research output: Contribution to journalArticle

Evidence for genetic susceptibility towards development of posttransplant lymphoproliferative disorder in solid organ recipients

Babel, N., Vergopoulos, A., Trappe, R. U., Oertel, S., Hammer, M. H., Karaivanov, S., Schneider, N., Riess, H., Papp-Vary, M., Neuhaus, R., Gondek, L. P., Volk, H. D. & Reinke, P., Aug 1 2007, In : Transplantation. 84, 3, p. 387-391 5 p.

Research output: Contribution to journalArticle

FISH and SNP-A karyotyping in myelodysplastic syndromes: Improving cytogenetic detection of del(5q), monosomy 7, del(7q), trisomy 8 and del(20q)

Makishima, H., Rataul, M., Gondek, L. P., Huh, J., Cook, J. R., Theil, K. S., Sekeres, M. A., Kuczkowski, E., O'Keefe, C. & Maciejewski, J. P., Apr 1 2010, In : Leukemia Research. 34, 4, p. 447-453 7 p.

Research output: Contribution to journalArticle

Genetic Alterations at Diagnosis Predict Outcome of AML Patients Age 60 or Older Undergoing Allogeneic Transplantation in First Remission

Murdock, H. M., Kim, H. T., Hambley, B., Vachhani, P., Denlinger, N., Gier, S. H., Cho, C., Perales, M. A., Koreth, J., Ho, V. T., Soiffer, R. J., McCurdy, S. R., Carroll, M., Vasu, S., Wang, E. S., Gondek, L. P., Devine, S., Alyea, E. P., Gibson, C. J. & Lindsley, R. C., Nov 13 2019, In : Blood. 134, 1, 1 p.

Research output: Contribution to journalArticle

Hedgehog/GLI1 activation leads to leukemic transformation of myelodysplastic syndrome in vivo and GLI1 inhibition results in antitumor activity

Lau, B., Huh, K., Madero-Marroquin, R., De Marchi, F., Lim, Y., Wang, Q., Lobo, F., Marchionni, L., Smith, B. D., Dezern, A., Levis, M. J., Aplan, P. D., Matsui, W. & Gondek, L., Jan 1 2018, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

High-Resolution Genomic Arrays Facilitate Detection of Novel Cryptic Chromosomal Lesions in Myelodysplastic Syndromes

O'Keefe, C. L., Tiu, R., Gondek, L. P., Powers, J., Theil, K. S., Kalaycio, M., Lichtin, A., Sekeres, M. A. & Maciejewski, J. P., Feb 1 2007, In : Experimental Hematology. 35, 2, p. 240-251 12 p.

Research output: Contribution to journalArticle

Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation

Brian Dalton, W., Helmenstine, E., Walsh, N., Gondek, L. P., Kelkar, D. S., Read, A., Natrajan, R., Christenson, E. S., Roman, B., Das, S., Zhao, L., Leone, R. D., Shinn, D., Groginski, T., Madugundu, A. K., Patil, A., Zabransky, D. J., Medford, A., Lee, J., Cole, A. J. & 12 others, Rosen, M., Thakar, M., Ambinder, A., Donaldson, J., DeZern, A. E., Cravero, K., Chu, D., Madero-Marroquin, R., Pandey, A., Hurley, P. J., Lauring, J. D. & Park, B. H., Nov 1 2019, In : Journal of Clinical Investigation. 129, 11, p. 4708-4723 16 p.

Research output: Contribution to journalArticle

Immunomodulation with pomalidomide at early lymphocyte recovery after induction chemotherapy in newly diagnosed AML and high-risk MDS

Zeidner, J. F., Knaus, H. A., Zeidan, A. M., Blackford, A. L., Montiel-Esparza, R., Hackl, H., Prince, G. T., Gondek, L. P., Ghiaur, G., Showel, M., DeZern, A. E., Pratz, K., Smith, B. D., Levis, M. J., Gore, S. D., Coombs, C. C., Foster, M. C., Streicher, H., Karp, J. E., Luznik, L. & 1 others, Gojo, I., Jun 1 2020, In : Leukemia. 34, 6, p. 1563-1576 14 p.

Research output: Contribution to journalArticle

Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia

Lim, Y., Gondek, L., Li, L., Wang, Q., Ma, H., Chang, E., Huso, D. L., Foerster, S., Marchionni, L., McGovern, K., Watkins, D. N., Peacock, C., Levis, M., Smith, B. D., Merchant, A. A., Small, D. & Matsui, W., Jun 10 2015, In : Science translational medicine. 7, 291, 96.

Research output: Contribution to journalArticle

Molecular analysis of alloreactive CTL post-hemopoietic stem cell transplantation

O'Keefe, C. L., Gondek, L., Davis, R., Kuczkowski, E., Sobecks, R. M., Rodriguez, A., Narvaez, Y., McIver, Z., Tuthill, R., Laughlin, M., Bolwell, B. & Maciejewski, J. P., Aug 1 2007, In : Journal of Immunology. 179, 3, p. 2013-2022 10 p.

Research output: Contribution to journalArticle

Open Access

Molecular strategies for detection and quantitation of clonal cytotoxic T-cell responses in aplastic anemia and myelodysplastic syndrome

Wlodarski, M. W., Gondek, L. P., Nearman, Z. P., Plasilova, M., Kalaycio, M., Hsi, E. D. & Maciejewski, J. P., Oct 15 2006, In : Blood. 108, 8, p. 2632-2641 10 p.

Research output: Contribution to journalArticle

New lesions detected by single nucleotide polymorphism array-based chromosomal analysis have important clinical impact in acute myeloid leukemia

Tiu, R. V., Gondek, L. P., O'Keefe, C. L., Huh, J., Sekeres, M. A., Elson, P., McDevitt, M. A., Wang, X. F., Levis, M. J., Karp, J. E., Advani, A. S. & Maciejewski, J. P., Nov 1 2009, In : Journal of Clinical Oncology. 27, 31, p. 5219-5226 8 p.

Research output: Contribution to journalArticle

P035 Improvement in cytogenetic diagnosis and clinical prognostication using SNP-A karyotyping in combination with metaphase cytogenetics in MDS, MDS/MPD and secondary AML

Tiu, R. V., Gondek, L. P., Huh, J., O'Keefe, C., Sekeres, M. A., Mufti, G. J., McDevitt, M. A., Advani, A. S. & Maciejewski, J., May 1 2009, In : Leukemia Research. 33, SUPPL. 1, p. S78-S79

Research output: Contribution to journalArticle

Prognostic impact of SNP array karyotyping in myelodysplastic syndromes and related myeloid malignancies

Tiu, R. V., Gondek, L. P., O'Keefe, C. L., Elson, P., Huh, J., Mohamedali, A., Kulasekararaj, A., Advani, A. S., Paquette, R., List, A. F., Sekeres, M. A., McDevitt, M. A., Mufti, G. J. & Maciejewski, J. P., Apr 28 2011, In : Blood. 117, 17, p. 4552-4560 9 p.

Research output: Contribution to journalArticle

Progressive chromatin repression and promoter methylation of CTNNA1 associated with advanced myeloid malignancies

Ye, Y., McDevitt, M. A., Guo, M., Zhang, W., Galm, O., Gore, S. D., Karp, J. E., Maciejewski, J. P., Kowalski, J., Tsai, H. L., Gondek, L. P., Tsai, H. C., Wang, X., Hooker, C. M., Smith, B. D., Carraway, H. & Herman, J. G., Nov 1 2009, In : Cancer Research. 69, 21, p. 8482-8490 9 p.

Research output: Contribution to journalArticle

SNP array karyotyping allows for the detection of uniparental disomy and cryptic chromosomal abnormalities in MDS/MPD-U and MPD

Gondek, L. P., Dunbar, A. J., Szpurka, H., McDevitt, M. A. & Maciejewski, J. P., Nov 21 2007, In : PloS one. 2, 11, e1225.

Research output: Contribution to journalArticle

The diagnostic utility of targeted gene panel sequencing in discriminating etiologies of cytopenia

Zheng, G., Chen, P., Pallavajjalla, A., Haley, L., Gondek, L., Dezern, A., Ling, H., De Marchi, F., Lin, M. T. & Gocke, C., Oct 1 2019, In : American journal of hematology. 94, 10, p. 1141-1148 8 p.

Research output: Contribution to journalArticle

Topography, clinical, and genomic correlates of 5q myeloid malignancies revisited

Jerez, A., Gondek, L. P., Jankowska, A. M., Makishima, H., Przychodzen, B., Tiu, R. V., O'Keefe, C. L., Mohamedali, A. M., Batista, D., Sekeres, M. A., McDevitt, M. A., Mufti, G. J. & Maciejewski, J. P., Apr 20 2012, In : Journal of Clinical Oncology. 30, 12, p. 1343-1349 7 p.

Research output: Contribution to journalArticle

UPD1p indicates the presence of MPL W515L mutation in RARS-T, a mechanism analogous to UPD9p and JAK2 V617F mutation

Szpurka, H., Gondek, L. P., Mohan, S. R., Hsi, E. D., Theil, K. S. & Maciejewski, J. P., Jan 1 2009, In : Leukemia. 23, 3, p. 610-614 5 p.

Research output: Contribution to journalArticle