Livia A Casciola Rosen

Professor

1987 …2019
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Research Output 1987 2019

2019

Anti–RNPC-3 (U11/U12) Antibodies in Systemic Sclerosis in Patients With Moderate-to-Severe Gastrointestinal Dysmotility

McMahan, Z., Domsic, R. T., Zhu, L., Medsger, T. A., Casciola Rosen, L. A. & Shah, A., Sep 1 2019, In : Arthritis Care and Research. 71, 9, p. 1164-1170 7 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Antibodies
Interstitial Lung Diseases
Gastrointestinal Diseases
African Americans

Estimating autoantibody signatures to detect autoimmune disease patient subsets

Wu, Z., Casciola Rosen, L. A., Shah, A., Rosen, A. & Zeger, S., Jan 1 2019, In : Biostatistics (Oxford, England). 20, 1, p. 30-47 18 p.

Research output: Contribution to journalArticle

Autoantibodies
Signature
Subset
Warping
Immune Response

Muscular and extramuscular features of myositis patients with anti-U1-RNP autoantibodies

Casal-Dominguez, M., Pinal-Fernandez, I., Corse, A. M., Paik, J., Albayda, J., Casciola Rosen, L. A., Johnson, C., Danoff, S., Christopher-Stine, L., Tiniakou, E. & Mammen, A. L., Mar 26 2019, In : Neurology. 92, 13, p. e1416-e1426

Research output: Contribution to journalArticle

Myositis
Ribonucleoproteins
Autoantibodies
Dermatomyositis
Muscular Diseases
RNA Polymerase I
RNA Polymerase III
Antibodies
Neoplasms
Anti-Idiotypic Antibodies
2018
Autoantibodies
Perineuronal Satellite Cells
Autoantigens
Spinal Ganglia
Antibodies

An update on autoantibodies in scleroderma

Mecoli, C. & Casciola Rosen, L. A., Nov 1 2018, In : Current opinion in rheumatology. 30, 6, p. 548-553 6 p.

Research output: Contribution to journalArticle

Autoantibodies
Antibody Specificity
Research
Blood Vessels
Neoplasms

Association between Autoantibody Phenotype and Cutaneous Adverse Reactions to Hydroxychloroquine in Dermatomyositis

Wolstencroft, P. W., Casciola Rosen, L. A. & Fiorentino, D. F., Jan 1 2018, (Accepted/In press) In : JAMA Dermatology.

Research output: Contribution to journalArticle

Hydroxychloroquine
Dermatomyositis
Autoantibodies
Phenotype
Skin
Autoantibodies
Phenotype
Neoplasms
Set theory
Incidence

Factors associated with clinical remission of skin disease in dermatomyositis

Wolstencroft, P. W., Chung, L., Li, S., Casciola Rosen, L. A. & Fiorentino, D. F., Jan 1 2018, In : JAMA Dermatology. 154, 1, p. 44-51 8 p.

Research output: Contribution to journalArticle

Dermatomyositis
Skin Diseases
Odds Ratio
Therapeutics
Antibodies
Open Access
Cell Shape
Epithelial Cells
Proteins
Autoantigens
Lip

Pre-existing antiacetylcholine receptor autoantibodies and B cell lymphopaenia are associated with the development of myositis in patients with thymoma treated with avelumab, an immune checkpoint inhibitor targeting programmed death-ligand 1

Mammen, A. L., Rajan, A., Pak, K., Lehky, T., Casciola Rosen, L. A., Donahue, R. N., Lepone, L. M., Zekeridou, A., Pittock, S. J., Hassan, R., Schlom, J. & Gulley, J. L., Jan 1 2018, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

Cholinergic Receptors
Autoantibodies
Monoclonal Antibodies
Cells
Ligands
2017

Antinuclear Matrix Protein 2 Autoantibodies and Edema, Muscle Disease, and Malignancy Risk in Dermatomyositis Patients

Albayda, J., Pinal-Fernandez, I., Huang, W., Parks, C., Paik, J., Casciola Rosen, L. A., Danoff, S., Johnson, C., Christopher-Stine, L. & Mammen, A. L., Nov 1 2017, In : Arthritis Care and Research. 69, 11, p. 1771-1776 6 p.

Research output: Contribution to journalArticle

Dermatomyositis
Autoantibodies
Edema
Muscles
Neoplasms

Association of Fibrosing Myopathy in Systemic Sclerosis and Higher Mortality

Paik, J., Wigley, F., Shah, A., Corse, A. M., Casciola Rosen, L. A., Hummers, L. & Mammen, A. L., Nov 1 2017, In : Arthritis Care and Research. 69, 11, p. 1764-1770 7 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Muscular Diseases
Muscles
Myositis
Mortality

Brief Report: Anti–RNPC-3 Antibodies As a Marker of Cancer-Associated Scleroderma

Shah, A., Xu, G., Rosen, A., Hummers, L., Wigley, F., Elledge, S. J. & Casciola Rosen, L. A., Jun 1 2017, In : Arthritis and Rheumatology. 69, 6, p. 1306-1312 7 p.

Research output: Contribution to journalArticle

Antibodies
Autoantibodies
Neoplasms
Cytidine Triphosphate
Odds Ratio

Cutaneous and Systemic Findings Associated With Nuclear Matrix Protein 2 Antibodies in Adult Dermatomyositis Patients

Rogers, A., Chung, L., Li, S., Casciola Rosen, L. A. & Fiorentino, D. F., 2017, (Accepted/In press) In : Arthritis Care and Research.

Research output: Contribution to journalArticle

Dermatomyositis
Skin
Antibodies
Myalgia
Deglutition Disorders
Myositis
Rheumatic Diseases
Autoantibodies
Dermatomyositis
Breast Neoplasms
Myositis
Phenotype
Antibodies
Polymyositis
Dermatomyositis

Longitudinal Course of Disease in a Large Cohort of Myositis Patients With Autoantibodies Recognizing the Signal Recognition Particle

Pinal-Fernandez, I., Parks, C., Werner, J. L., Albayda, J., Paik, J., Danoff, S., Casciola Rosen, L. A., Christopher-Stine, L. & Mammen, A. L., Feb 1 2017, In : Arthritis Care and Research. 69, 2, p. 263-270 8 p.

Research output: Contribution to journalArticle

Signal Recognition Particle
Myositis
Autoantibodies
Hydroxymethylglutaryl CoA Reductases
Muscular Diseases

Mechanistic and clinical insights at the scleroderma-cancer interface

Shah, A. & Casciola Rosen, L. A., Jan 1 2017, In : Journal of Scleroderma and Related Disorders. 2, 3, p. 153-159 7 p.

Research output: Contribution to journalReview article

Neoplasms
Autoimmunity
Immunosuppressive Agents
Inflammation
Therapeutics
Muscular Diseases
Oxidoreductases
Myositis
Exome
Immunosuppressive Agents
Neuromyelitis Optica
Central Nervous System Diseases
Autoimmunity
Antibodies
Immunosuppressive Agents

Reply

Baer, A., Petri, M., Sohn, J., Rosen, A. & Casciola Rosen, L. A., Mar 1 2017, In : Arthritis Care and Research. 69, 3, p. 454 1 p.

Research output: Contribution to journalLetter

Reply

Shah, A., Rosen, A., Hummers, L., Wigley, F., Xu, G., Elledge, S. J. & Casciola Rosen, L. A., Sep 1 2017, In : Arthritis and Rheumatology. 69, 9, p. 1915-1916 2 p.

Research output: Contribution to journalLetter

Blood Vessels
Antibodies
Anti-Idiotypic Antibodies
Proteins
Gangrene
2016
Gangrene
Interferons
Antibodies
Proteins
Case-Control Studies
Interferons
Antibodies
Proteins
Salivary Glands
Lip
Autoantigens
Rheumatic Diseases
Autoimmune Diseases
Autoimmunity
Immune System

Cytosolic 5′-Nucleotidase 1A As a Target of Circulating Autoantibodies in Autoimmune Diseases

Lloyd, T., Christopher-Stine, L., Pinal-Fernandez, I., Tiniakou, E., Petri, M., Baer, A., Danoff, S., Pak, K., Casciola Rosen, L. A. & Mammen, A. L., Jan 1 2016, In : Arthritis Care and Research. 68, 1, p. 66-71 6 p.

Research output: Contribution to journalArticle

5'-Nucleotidase
Autoantibodies
Autoimmune Diseases
Inclusion Body Myositis
Dermatomyositis

Enrichment of Scleroderma Vascular Disease–Associated Autoantigens in Endothelial Lineage Cells

McMahan, Z., Cottrell, T. R., Wigley, F., Antiochos, B., Zambidis, E., Park, T. S., Halushka, M. K., Gutierrez, L., Cimbro, R., Rosen, A. & Casciola Rosen, L. A., Oct 1 2016, In : Arthritis and Rheumatology. 68, 10, p. 2540-2549 10 p.

Research output: Contribution to journalArticle

Autoantigens
Interferons
Blood Vessels
Endothelial Cells
Proteins

Ovoid palatal patch in dermatomyositis: A novel finding associated with Anti-TIF1γ (p155) antibodies

Bernet, L. L., Lewis, M. A., Rieger, K. E., Casciola Rosen, L. A. & Fiorentino, D. F., Sep 1 2016, In : JAMA Dermatology. 152, 9, p. 1049-1051 3 p.

Research output: Contribution to journalLetter

Dermatomyositis
Antibodies

Statin-Induced Anti-HMGCR-Associated Myopathy

Basharat, P., Lahouti, A. H., Paik, J. J., Albayda, J., Pinal-Fernandez, I., Bichile, T., Lloyd, T. E., Danoff, S. K., Casciola-Rosen, L., Mammen, A. L. & Christopher-Stine, L., Jul 12 2016, In : Journal of the American College of Cardiology. 68, 2, p. 234-235 2 p.

Research output: Contribution to journalLetter

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Muscular Diseases

Systematic autoantigen analysis identifies a distinct subtype of scleroderma with coincident cancer

Xu, G. J., Shah, A., Li, M. Z., Xu, Q., Rosen, A., Casciola Rosen, L. A. & Elledge, S. J., Nov 22 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 47, p. E7526-E7534

Research output: Contribution to journalArticle

Autoantigens
Spliceosomes
Autoantibodies
Autoimmune Diseases
Epitopes
2015
RNA Polymerase III
Neoplasms
Autoantibodies
Mutation
Early Detection of Cancer

Cutaneous ulceration in dermatomyositis: Association with anti-melanoma differentiation-associated gene 5 antibodies and interstitial lung disease

Narang, N. S., Casciola Rosen, L. A., Li, S., Chung, L. & Fiorentino, D. F., May 1 2015, In : Arthritis Care and Research. 67, 5, p. 667-672 6 p.

Research output: Contribution to journalArticle

Dermatomyositis
Interstitial Lung Diseases
Ulcer
Melanoma
Skin Ulcer

Distinctive cutaneous and systemic features associated with antitranscriptional intermediary factor-1γ antibodies in adults with dermatomyositis

Fiorentino, D. F., Kuo, K., Chung, L., Zaba, L., Li, S. & Casciola Rosen, L. A., Mar 1 2015, In : Journal of the American Academy of Dermatology. 72, 3, p. 449-455 7 p.

Research output: Contribution to journalArticle

Dermatomyositis
Skin
Antibodies
Autoantibodies
transcriptional intermediary factor 1
Autoantibodies
RNA Polymerase III
Neoplasms
Age of Onset
Type I DNA Topoisomerase

Expression of the dermatomyositis autoantigen transcription intermediary factor 1γ in regenerating muscle

Mohassel, P., Rosen, P., Casciola Rosen, L. A., Pak, K. & Mammen, A. L., Jan 1 2015, In : Arthritis and Rheumatology. 67, 1, p. 266-272 7 p.

Research output: Contribution to journalArticle

Dermatomyositis
Autoantigens
Transcription Factors
Muscles
Myoblasts

Molecular subsetting of interferon pathways in Sjögren's syndrome

Hall, J. C., Baer, A., Shah, A., Criswell, L. A., Shiboski, C. H., Rosen, A. & Casciola Rosen, L. A., Sep 1 2015, In : Arthritis and Rheumatology. 67, 9, p. 2437-2446 10 p.

Research output: Contribution to journalArticle

Interferons
Salivary Glands
Lip
Interferon-gamma
Lacrimal Apparatus
Inborn Genetic Diseases
Myositis
Autoantibodies
Muscles
Dermatomyositis
Raynaud Disease
Antibodies
Body Temperature Regulation
Autoantibodies
Serum

PUF60: A prominent new target of the autoimmune response in dermatomyositis and Sjögren's syndrome

Fiorentino, D. F., Presby, M., Baer, A., Petri, M., Rieger, K. E., Soloski, M. J., Rosen, A., Mammen, A. L., Christopher-Stine, L. & Casciola Rosen, L. A., Aug 7 2015, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

Dermatomyositis
Autoimmunity
Antibodies
Autoantigens
Autoantibodies

Review: Cancer-induced autoimmunity in the rheumatic diseases

Shah, A., Casciola Rosen, L. A. & Rosen, A., Feb 1 2015, In : Arthritis and Rheumatology. 67, 2, p. 317-326 10 p.

Research output: Contribution to journalArticle

Dermatomyositis
Systemic Scleroderma
Rheumatic Diseases
Autoimmunity
Autoimmune Diseases

Spectrum of Muscle Histopathologic Findings in Forty-Two Scleroderma Patients with Weakness

Paik, J., Wigley, F., Lloyd, T., Corse, A. M., Casciola Rosen, L. A., Shah, A., Boin, F., Hummers, L. & Mammen, A. L., Oct 1 2015, In : Arthritis Care and Research. 67, 10, p. 1416-1425 10 p.

Research output: Contribution to journalArticle

Muscular Diseases
Fibrosis
Myositis
Denervation
Muscles
Dermatomyositis
Autoantibodies
Biopsy
Polymyositis
Muscles
2014

Anti-MDA5 positive clinically amyopathic dermatomyositis presenting with severe cardiomyopathy

Pau-Charles, I., Moreno, P. J., Ortiz-Ibáñez, K., Lucero, M. C., Garcia-Herrera, A., Espinosa, G., Nicolás, J. M., Castro, P., Grau, J. M., Casciola Rosen, L. A. & Mascarõ, J. M., 2014, In : Journal of the European Academy of Dermatology and Venereology. 28, 8, p. 1097-1102 6 p.

Research output: Contribution to journalArticle

Dermatomyositis
Cardiomyopathies
Panniculitis
Chills
Skin

Association of the autoimmune disease scleroderma with an immunologic response to cancer

Joseph, C. G., Darrah, E., Shah, A., Skora, A. D., Casciola Rosen, L. A., Wigley, F., Boin, F., Fava, A., Thoburn, C., Kinde, I., Jiao, Y., Papadopoulos, N., Kinzler, K. W., Vogelstein, B. & Rosen, A., 2014, In : Science. 343, 6167, p. 152-157 6 p.

Research output: Contribution to journalArticle

Autoimmune Diseases
Neoplasms
Antibodies
Antigens
Connective Tissue Diseases

Clinical and pathologic differences in interstitial lung disease based on antisynthetase antibody type

Johnson, C., Connors, G. R., Oaks, J., Han, S., Truong, A., Richardson, B., Lechtzin, N., Mammen, A. L., Casciola Rosen, L. A., Christopher-Stine, L. & Danoff, S., Oct 1 2014, In : Respiratory Medicine. 108, 10, p. 1542-1548 7 p.

Research output: Contribution to journalArticle

Interstitial Lung Diseases
Myositis
Antibodies
Polymyositis
Dermatomyositis

Identification of clinical features and autoantibodies associated with calcinosis in dermatomyositis

Valenzuela, A., Chung, L., Casciola Rosen, L. A. & Fiorentino, D., 2014, In : JAMA Dermatology. 150, 7, p. 724-729 6 p.

Research output: Contribution to journalArticle

Calcinosis
Dermatomyositis
Autoantibodies
Ulcer
Odds Ratio
2013

Anti-melanoma differentiation-associated protein 5-associated dermatomyositis: Expanding the clinical spectrum

Hall, J. C., Casciola Rosen, L. A., Samedy, L. A., Werner, J., Owoyemi, K., Danoff, S. & Christopher-Stine, L., Aug 2013, In : Arthritis Care and Research. 65, 8, p. 1307-1315 9 p.

Research output: Contribution to journalArticle

Dermatomyositis
Autoantibodies
Interstitial Lung Diseases
Myositis
Muscular Diseases

Most patients with cancer-associated dermatomyositis have antibodies to nuclear matrix protein NXP-2 or transcription intermediary factor 1γ

Fiorentino, D. F., Chung, L. S., Christopher-Stine, L., Zaba, L., Li, S., Mammen, A. L., Rosen, A. & Casciola Rosen, L. A., Nov 2013, In : Arthritis and Rheumatism. 65, 11, p. 2954-2962 9 p.

Research output: Contribution to journalArticle

Dermatomyositis
Transcription Factors
Antibodies
Neoplasms
Immunoprecipitation