Lisa Yanek

Assistant Professor

1993 …2019
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Research Output 1993 2019

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Article
2019

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

Kraja, A. T., Liu, C., Fetterman, J. L., Graff, M., Have, C. T., Gu, C., Yanek, L., Feitosa, M. F., Arking, D., Chasman, D. I., Young, K., Ligthart, S., Hill, W. D., Weiss, S., Luan, J., Giulianini, F., Li-Gao, R., Hartwig, F. P., Lin, S. J., Wang, L. & 132 others, Richardson, T. G., Yao, J., Fernandez, E. P., Ghanbari, M., Wojczynski, M. K., Lee, W. J., Argos, M., Armasu, S. M., Barve, R. A., Ryan, K. A., An, P., Baranski, T. J., Bielinski, S. J., Bowden, D. W., Broeckel, U., Christensen, K., Chu, A. Y., Corley, J., Cox, S. R., Uitterlinden, A. G., Rivadeneira, F., Cropp, C. D., Daw, E. W., van Heemst, D., de las Fuentes, L., Gao, H., Tzoulaki, I., Ahluwalia, T. S., de Mutsert, R., Emery, L. S., Erzurumluoglu, A. M., Perry, J. A., Fu, M., Forouhi, N. G., Gu, Z., Hai, Y., Harris, S. E., Hemani, G., Hunt, S. C., Irvin, M. R., Jonsson, A. E., Justice, A. E., Kerrison, N. D., Larson, N. B., Lin, K. H., Love-Gregory, L. D., Mathias, R., Lee, J. H., Nauck, M., Noordam, R., Ong, K. K., Pankow, J., Patki, A., Pattie, A., Petersmann, A., Qi, Q., Ribel-Madsen, R., Rohde, R., Sandow, K., Schnurr, T. M., Sofer, T., Starr, J. M., Taylor, A. M., Teumer, A., Timpson, N. J., de Haan, H. G., Wang, Y., Weeke, P. E., Williams, C., Wu, H., Yang, W., Zeng, D., Witte, D. R., Weir, B. S., Wareham, N. J., Vestergaard, H., Turner, S. T., Torp-Pedersen, C., Stergiakouli, E., Sheu, W. H. H., Rosendaal, F. R., Ikram, M. A., Franco, O. H., Ridker, P. M., Perls, T. T., Pedersen, O., Nohr, E. A., Newman, A. B., Linneberg, A., Langenberg, C., Kilpeläinen, T. O., Kardia, S. L. R., Jørgensen, M. E., Jørgensen, T., Sørensen, T. I. A., Homuth, G., Hansen, T., Goodarzi, M. O., Deary, I. J., Christensen, C., Chen, Y. D. I., Chakravarti, A., Brandslund, I., Bonnelykke, K., Taylor, K. D., Wilson, J. G., Rodriguez, S., Davies, G., Horta, B. L., Thyagarajan, B., Rao, D. C., Grarup, N., Davila-Roman, V. G., Hudson, G., Guo, X., Arnett, D. K., Hayward, C., Vaidya, D., Mook-Kanamori, D. O., Tiwari, H. K., Levy, D., Loos, R. J. F., Dehghan, A., Elliott, P., Malik, A. N., Scott, R. A., Becker, D. M., de Andrade, M., Province, M. A., Meigs, J. B., Rotter, J. I. & North, K. E., Jan 3 2019, In : American Journal of Human Genetics. 104, 1, p. 112-138 27 p.

Research output: Contribution to journalArticle

Mitochondrial Genes
Mitochondria
Mitochondrial DNA
Genes
Waist-Hip Ratio

Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies

TOPMed Hematology and Hemostasis Working Group & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Feb 7 2019, In : American journal of human genetics. 104, 2, p. 260-274 15 p.

Research output: Contribution to journalArticle

Genome
Precision Medicine
National Heart, Lung, and Blood Institute (U.S.)
Genetic Testing
Pedigree

Evolution of Hominin Polyunsaturated Fatty Acid Metabolism: From Africa to the New World

Harris, D. N., Ruczinski, I., Yanek, L., Becker, L., Becker, D. M., Guio, H., Cui, T., Chilton, F. H., Mathias, R. & O'Connor, T. D., May 1 2019, In : Genome biology and evolution. 11, 5, p. 1417-1430 14 p.

Research output: Contribution to journalArticle

Open Access
Fatty Acid Desaturases
stearoyl-CoA desaturase
fatty acid metabolism
Hominidae
Unsaturated Fatty Acids

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels

INVENT Consortium; MEGASTROKE Consortium of the International Stroke Genetics Consortium (ISGC), Jan 29 2019, In : Circulation. 139, 5, p. 620-635 16 p.

Research output: Contribution to journalArticle

Factor VIII
Meta-Analysis
von Willebrand Factor
Genome
Venous Thrombosis

Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data

NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Blood Pressure Working Group, Feb 8 2019, In : Human genetics. 138, 2, p. 199-210 12 p.

Research output: Contribution to journalArticle

Precision Medicine
Genome
Blood Pressure
Genes
Exome

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

Ward-Caviness, C. K., De Vries, P. S., Wiggins, K. L., Huffman, J. E., Yanek, L., Bielak, L. F., Giulianini, F., Guo, X., Kleber, M. E., Kacprowski, T., Groß, S., Petersman, A., Smith, G. D., Hartwig, F. P., Bowden, J., Hemani, G., Müller-Nuraysid, M., Strauch, K., Koenig, W., Waldenberger, M. & 38 others, Meitinger, T., Pankratz, N., Boerwinkle, E., Tang, W., Fu, Y. P., Johnson, A. D., Song, C., De Maat, M. P. M., Uitterlinden, A. G., Franco, O. H., Brody, J. A., McKnight, B., Chen, Y. D. I., Psaty, B. M., Mathias, R., Becker, D. M., Peyser, P. A., Smith, J. A., Bielinski, S. J., Ridker, P. M., Taylor, K. D., Yao, J., Tracy, R., Delgado, G., Trompet, S., Sattar, N., Jukema, J. W., Becker, L., Kardia, S. L. R., Rotter, J. I., März, W., Dörr, M., Chasman, D. I., Dehghan, A., O’Donnell, C. J., Smith, N. L., Peters, A. & Morrison, A. C., May 1 2019, In : PloS one. 14, 5, e0216222.

Research output: Contribution to journalArticle

Open Access
fibrinogen
Random Allocation
Fibrinogen
Coronary Disease
Mendelian Randomization Analysis

Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Lifelines Cohort, Groningen, The Netherlands (Lifelines Cohort Study) & InterAct Consortium, Jun 1 2019, In : American journal of epidemiology. 188, 6, p. 1033-1054 22 p.

Research output: Contribution to journalArticle

Open Access
Genome-Wide Association Study
Alcohols
Lipids
Vascular Endothelial Growth Factor B
Proprotein Convertases

Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

Understanding Society Scientific group, Lifelines Cohort, COGENT-Kidney Consortium & EPIC-InterAct Consortium, Apr 1 2019, In : Nature genetics. 51, 4, p. 636-648 13 p.

Research output: Contribution to journalArticle

Smoking
Genome
Lipids
Life Style
Serum
Open Access
Delirium
Spinal Anesthesia
General Anesthesia
Anesthetics
Spine
2018

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

The CHARGE Neurology Working Group, Mar 1 2018, In : American Journal of Human Genetics. 102, 3, p. 375-400 26 p.

Research output: Contribution to journalArticle

Smoking
Genome
Blood Pressure
Genome-Wide Association Study
Blood Vessels

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

NHLBI TOPMed Lipids Working Group, Dec 1 2018, In : Nature Communications. 9, 1, 3391.

Research output: Contribution to journalArticle

sequencing
genome
cholesterol
lipoproteins
blood

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Zekavat, S. M., Ruotsalainen, S., Handsaker, R. E., Alver, M., Bloom, J., Poterba, T., Seed, C., Ernst, J., Chaffin, M., Engreitz, J., Peloso, G. M., Manichaikul, A., Yang, C., Ryan, K. A., Fu, M., Johnson, W. C., Tsai, M., Budoff, M., Ramachandran, V. S., Cupples, L. A. & 323 others, Rotter, J. I., Rich, S. S., Post, W. S., Mitchell, B. D., Correa, A., Metspalu, A., Wilson, J. G., Salomaa, V., Kellis, M., Daly, M. J., Neale, B. M., McCarroll, S., Surakka, I., Esko, T., Ganna, A., Ripatti, S., Kathiresan, S., Natarajan, P., Abe, N., Abecasis, G., Albert, C., Allred, N. P., Almasy, L., Alonso, A., Ament, S., Anderson, P., Anugu, P., Applebaum-Bowden, D., Arking, D., Arnett, D. K., Ashley-Koch, A., Aslibekyan, S., Assimes, T., Auer, P., Avramopoulos, D., Barnard, J., Barnes, K., Barr, R. G., Barron-Casella, E., Beaty, T. L., Becker, D. M., Becker, L., Beer, R., Begum, F., Beitelshees, A., Benjamin, E., Bezerra, M., Bielak, L., Bis, J., Blackwell, T., Blangero, J., Boerwinkle, E., Borecki, I., Bowler, R., Brody, J., Broeckel, U., Broome, J., Bunting, K., Burchard, E., Cardwell, J., Carty, C., Casaburi, R., Casella, J. F., Chang, C., Chasman, D., Chavan, S., Chen, B. J., Chen, W. M., Chen, Y. D. I., Cho, M., Choi, S. H., Chuang, L. M., Chung, M., Cornell, E., Crandall, C., Crapo, J., Curran, J., Curtis, J., Custer, B., Damcott, C., Darbar, D., Das, S., David, S., Davis, C., Daya, M., Andrade, M. D., Debaun, M., Deka, R., Demeo, D., Devine, S., Do, R., Duan, Q., Duggirala, R., Durda, P., Dutcher, S., Eaton, C., Ekunwe, L., Ellinor, P., Emery, L., Farber, C., Farnam, L., Fingerlin, T., Flickinger, M., Fornage, M., Franceschini, N., Fullerton, S. M., Fulton, L., Gabriel, S., Gan, W., Gao, Y., Gass, M., Gelb, B., Geng, X., Germer, S., Gignoux, C., Gladwin, M., Glahn, D., Gogarten, S., Gong, D. W., Goring, H., Gu, C. C., Guan, Y., Guo, X., Haessler, J., Hall, M., Harris, D., Hawley, N., He, J., Heavner, B., Heckbert, S., Hernandez, R., Herrington, D., Hersh, C., Hidalgo, B., Hixson, J., Hokanson, J., Hong, E., Hoth, K., Hsiung, C., Huston, H., Hwu, C. M., Irvin, M. R., Jackson, R., Jain, D., Jaquish, C., Jhun, M. A., Johnsen, J., Johnson, A., Johnston, R., Jones, K., Kang, H. M., Kaplan, R., Kardia, S., Kaufman, L., Kelly, S., Kenny, E., Kessler, M., Khan, A., Kinney, G., Konkle, B., Kooperberg, C., Kramer, H., Krauter, S., Lange, C., Lange, E., Lange, L., Laurie, C., Laurie, C., Leboff, M., Lee, S. S., Lee, W. J., Lefaive, J., Levine, D., Levy, D., Lewis, J., Li, Y., Lin, H., Lin, K. H., Liu, S., Liu, Y., Loos, R., Lubitz, S., Lunetta, K., Luo, J., Mahaney, M., Make, B., Manson, J. A., Margolin, L., Martin, L., Mathai, S., Mathias, R., McArdle, P., McDonald, M. L., McFarland, S., McGarvey, S., Mei, H., Meyers, D. A., Mikulla, J., Min, N., Minear, M., Minster, R. L., Montasser, M. E., Musani, S., Mwasongwe, S., Mychaleckyj, J. C., Nadkarni, G., Naik, R. P., Nekhai, S., Nickerson, D., North, K., O'connell, J., O'connor, T., Ochs-Balcom, H., Pankow, J., Papanicolaou, G., Parker, M., Parsa, A., Penchev, S., Peralta, J. M., Perez, M., Perry, J., Peters, U., Peyser, P., Phillips, L., Phillips, S., Pollin, T., Becker, J. P., Boorgula, M. P., Preuss, M., Prokopenko, D., Psaty, B., Qasba, P., Qiao, D., Qin, Z., Rafaels, N., Raffield, L., Rao, D. C., Rasmussen-Torvik, L., Ratan, A., Redline, S., Reed, R., Regan, E., Reiner, A., Rice, K., Roden, D., Roselli, C., Ruczinski, I., Russell, P., Ruuska, S., Sakornsakolpat, P., Salimi, S., Salzberg, S. L., Sandow, K., Sankaran, V., Scheller, C., Schmidt, E., Schwander, K., Schwartz, D., Sciurba, F., Seidman, C., Sheehan, V., Shetty, A., Shetty, A., Sheu, W. H. H., Shoemaker, M. B., Silver, B., Silverman, E., Smith, J., Smith, J., Smith, N., Smith, T., Smoller, S., Snively, B., Sofer, T., Sotoodehnia, N., Stilp, A., Streeten, E., Sung, Y. J., Sylvia, J., Szpiro, A., Sztalryd, C., Taliun, D., Tang, H., Taub, M. A., Taylor, K., Taylor, S., Telen, M., Thornton, T. A., Tinker, L., Tirschwell, D., Tiwari, H., Tracy, R., Vaidya, D., Vandehaar, P., Vrieze, S., Walker, T., Wallace, R., Walts, A., Wan, E., Wang, F. F., Watson, K., Weeks, D. E., Weir, B., Weiss, S., Weng, L. C., Willer, C., Williams, K., Williams, L. K., Wilson, C., Wong, Q., Xu, H., Yanek, L., Yang, I., Yang, R., Zaghloul, N., Zhang, Y., Zhao, S. X., Zhao, W., Zheng, X., Zhi, D., Zhou, X., Zody, M. & Zoellner, S., Dec 1 2018, In : Nature Communications. 9, 1, 2606.

Research output: Contribution to journalArticle

lipoproteins
Lipoprotein(a)
genome
Cardiovascular Diseases
Genes

Diabetes and Platelet Response to Low-Dose Aspirin

Al-Sofiani, M. E., Yanek, L., Faraday, N., Kral, B. G., Mathias, R., Becker, L., Becker, D. M., Vaidya, D. & Kalyani, R. R., Dec 1 2018, In : The Journal of clinical endocrinology and metabolism. 103, 12, p. 4599-4608 10 p.

Research output: Contribution to journalArticle

Medical problems
Platelets
Aspirin
Blood Platelets
Platelet Activation

Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging

neuroCHARGE Working Group, Aug 1 2018, In : Stroke. 49, 8, p. 1812-1819 8 p.

Research output: Contribution to journalArticle

Exome
Magnetic Resonance Imaging
Brain
Meta-Analysis
Cerebral Small Vessel Diseases

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Lifelines Cohort Study & CHARGE Inflammation working group, Nov 1 2018, In : American Journal of Human Genetics. 103, 5, p. 691-706 16 p.

Research output: Contribution to journalArticle

C-Reactive Protein
Genome
Inflammation
Mendelian Randomization Analysis
Genome-Wide Association Study

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

Vojinovic, D., Adams, H. H., Jian, X., Yang, Q., Smith, A. V., Bis, J. C., Teumer, A., Scholz, M., Armstrong, N. J., Hofer, E., Saba, Y., Luciano, M., Bernard, M., Trompet, S., Yang, J., Gillespie, N. A., van der Lee, S. J., Neumann, A., Ahmad, S., Andreassen, O. A. & 71 others, Ames, D., Amin, N., Arfanakis, K., Bastin, M. E., Becker, D. M., Beiser, A. S., Beyer, F., Brodaty, H., Bryan, R. N., Bülow, R., Dale, A. M., De Jager, P. L., Deary, I. J., DeCarli, C., Fleischman, D. A., Gottesman, R. F., van der Grond, J., Gudnason, V., Harris, T. B., Homuth, G., Knopman, D. S., Kwok, J. B., Lewis, C. E., Li, S., Loeffler, M., Lopez, O. L., Maillard, P., El Marroun, H., Mather, K. A., Mosley, T. H., Muetzel, R. L., Nauck, M., Nyquist, P. A., Panizzon, M. S., Pausova, Z., Psaty, B. M., Rice, K., Rotter, J. I., Royle, N., Satizabal, C. L., Schmidt, R., Schofield, P. R., Schreiner, P. J., Sidney, S., Stott, D. J., Thalamuthu, A., Uitterlinden, A. G., Valdés Hernández, M. C., Vernooij, M. W., Wen, W., White, T., Witte, A. V., Wittfeld, K., Wright, M. J., Yanek, L., Tiemeier, H., Kremen, W. S., Bennett, D. A., Jukema, J. W., Paus, T., Wardlaw, J. M., Schmidt, H., Sachdev, P. S., Villringer, A., Grabe, H. J., Longstreth, W. T., van Duijn, C. M., Launer, L. J., Seshadri, S., Ikram, M. A. & Fornage, M., Dec 1 2018, In : Nature Communications. 9, 1, 3945.

Research output: Contribution to journalArticle

genome
Lateral Ventricles
Genome-Wide Association Study
loci
brain

Genome-wide association study of heavy smoking and daily/nondaily smoking in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Saccone, N. L., Emery, L. S., Sofer, T., Gogarten, S. M., Becker, D. M., Bottinger, E. P., Chen, L. S., Culverhouse, R. C., Duan, W., Hancock, D. B., Hosgood, H. D., Johnson, E. O., Loos, R. J. F., Louie, T., Papanicolaou, G., Perreira, K. M., Rodriquez, E. J., Schurmann, C., Stilp, A. M., Szpiro, A. A. & 8 others, Talavera, G. A., Taylor, K. D., Thrasher, J. F., Yanek, L., Laurie, C. C., Pérez-Stable, E. J., Bierut, L. J. & Kaplan, R. C., Mar 6 2018, In : Nicotine and Tobacco Research. 20, 4, p. 448-457 10 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Hispanic Americans
Smoking
Health
Nicotinic Receptors
Anisotropy
Hypertension
Linear Models
Blood Pressure
Leukoencephalopathies

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

Feitosa, M. F., Kraja, A. T., Chasman, D. I., Sung, Y. J., Winkler, T. W., Ntalla, I., Guo, X., Franceschini, N., Cheng, C. Y., Sim, X., Vojinovic, D., Marten, J., Musani, S. K., Li, C., Bentley, A. R., Brown, M. R., Schwander, K., Richard, M. A., Noordam, R., Aschard, H. & 252 others, Bartz, T. M., Bielak, L. F., Dorajoo, R., Fisher, V., Hartwig, F. P., Horimoto, A. R. V. R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Wojczynski, M. K., Alver, M., Boissel, M., Cai, Q., Campbell, A., Chai, J. F., Chen, X., Divers, J., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., He, M., Hsu, F. C., Jackson, A. U., Kähönen, M., Kasturiratne, A., Komulainen, P., Kühnel, B., Laguzzi, F., Luan, JA., Matoba, N., Nolte, I. M., Padmanabhan, S., Riaz, M., Rueedi, R., Robino, A., Said, M. A., Scott, R. A., Sofer, T., Stančáková, A., Takeuchi, F., Tayo, B. O., Van Der Most, P. J., Varga, T. V., Vitart, V., Wang, Y., Ware, E. B., Warren, H. R., Weiss, S., Wen, W., Yanek, L., Zhang, W., Zhao, J. H., Afaq, S., Amin, N., Amini, M., Arking, D., Aung, T., Boerwinkle, E., Borecki, I., Broeckel, U., Brown, M., Brumat, M., Burke, G. L., Canouil, M., Chakravarti, A., Charumathi, S., Chen, Y. D. I., Connell, J. M., Correa, A., De Las Fuentes, L., De Mutsert, R., De Silva, H. J., Deng, X., Ding, J., Duan, Q., Eaton, C. B., Ehret, G., Eppinga, R. N., Evangelou, E., Faul, J. D., Felix, S. B., Forouhi, N. G., Forrester, T., Franco, O. H., Friedlander, Y., Gandin, I., Gao, H., Ghanbari, M., Gigante, B., Gu, C. C., Gu, D., Hagenaars, S. P., Hallmans, G., Harris, T. B., He, J., Heikkinen, S., Heng, C. K., Hirata, M., Howard, B. V., Ikram, M. A., John, U., Katsuya, T., Khor, C. C., Kilpeläinen, T. O., Koh, W. P., Krieger, J. E., Kritchevsky, S. B., Kubo, M., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lehne, B., Lewis, C. E., Li, Y., Lin, S., Liu, J., Liu, J., Loh, M., Louie, T., Mägi, R., McKenzie, C. A., Meitinger, T., Metspalu, A., Milaneschi, Y., Milani, L., Mohlke, K. L., Momozawa, Y., Nalls, M. A., Nelson, C. P., Sotoodehnia, N., Norris, J. M., O'Connell, J. R., Palmer, N. D., Perls, T., Pedersen, N. L., Peters, A., Peyser, P. A., Poulter, N., Raffel, L. J., Raitakari, O. T., Roll, K., Rose, L. M., Rosendaal, F. R., Rotter, J. I., Schmidt, C. O., Schreiner, P. J., Schupf, N., Scott, W. R., Sever, P. S., Shi, Y., Sidney, S., Sims, M., Sitlani, C. M., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Stringham, H. M., Tan, N. Y. Q., Tang, H., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Turner, S. T., Uitterlinden, A. G., Vollenweider, P., Waldenberger, M., Wang, L., Wang, Y. X., Wei, W. B., Williams, C., Yao, J., Yu, C., Yuan, J. M., Zhao, W., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Deary, I. J., Esko, T., Farrall, M., Franks, P. W., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Jonas, J. B., Kamatani, Y., Kato, N., Kooner, J. S., Kutalik, Z., Laakso, M., Laurie, C. C., Leander, K., Lehtimäki, T., Magnusson, P. K. E., Oldehinkel, A. J., Penninx, B. W. J. H., Polasek, O., Porteous, D. J., Rauramaa, R., Samani, N. J., Scott, J., Shu, X. O., Van Der Harst, P., Wagenknecht, L. E., Wareham, N. J., Watkins, H., Weir, D. R., Wickremasinghe, A. R., Wu, T., Zheng, W., Bouchard, C., Christensen, K., Evans, M. K., Gudnason, V., Horta, B. L., Kardia, S. L. R., Liu, Y., Pereira, A. C., Psaty, B. M., Ridker, P. M., Van Dam, R. M., Gauderman, W. J., Zhu, X., Mook-Kanamori, D. O., Fornage, M., Rotimi, C. N., Cupples, L. A., Kelly, T. N., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Kooperberg, C., Palmas, W., Rice, K., Morrison, A. C., Elliott, P., Caulfield, M. J., Munroe, P. B., Rao, D. C., Province, M. A. & Levy, D., Jun 1 2018, In : PLoS One. 13, 6, e0198166.

Research output: Contribution to journalArticle

Blood pressure
blood pressure
ancestry
alcohols
Genes

Targeted deep sequencing of the PEAR1 locus for platelet aggregation in European and African American families

Keramati, A. R., Yanek, L., Iyer, K., Taub, M. A., Ruczinski, I., Becker, D. M., Becker, L., Faraday, N. & Mathias, R., Mar 18 2018, (Accepted/In press) In : Platelets. p. 1-7 7 p.

Research output: Contribution to journalArticle

High-Throughput Nucleotide Sequencing
Platelet Aggregation
African Americans
Aspirin
Genome-Wide Association Study
Type 2 Diabetes Mellitus
African Americans
Siblings
Coronary Artery Disease
Atherosclerosis
2017

A novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women

MEDIA Consortium, Mar 1 2017, In : PLoS One. 12, 3, e0172577.

Research output: Contribution to journalArticle

African Americans
Medical problems
noninsulin-dependent diabetes mellitus
Type 2 Diabetes Mellitus
Single Nucleotide Polymorphism

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African ancestry anthropometry genetics consortium

The Bone Mineral Density in Childhood Study (BMDCS) Group, Apr 1 2017, In : PLoS Genetics. 13, 4, e1006719.

Research output: Contribution to journalArticle

Anthropometry
Genome-Wide Association Study
Adiposity
adiposity
anthropometric measurements

Exome-chip meta-analysis identifies association between variation in ANKRD26 and platelet aggregation

Chen, M. H., Yanek, L., Backman, J. D., Eicher, J. D., Huffman, J. E., Ben-Shlomo, Y., Beswick, A. D., Yerges-Armstrong, L. M., Shuldiner, A. R., O’Connell, J. R., Mathias, R., Becker, D. M., Becker, L., Lewis, J. P., Johnson, A. D. & Faraday, N., Nov 30 2017, (Accepted/In press) In : Platelets. p. 1-10 10 p.

Research output: Contribution to journalArticle

Exome
Platelet Aggregation
Meta-Analysis
Blood Platelets
Adenosine Diphosphate

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., Shen, X., Gandin, I., McDaid, A. F., Hansen, T. F., Gordon, S. D., Giulianini, F., Boutin, T. S., Abdellaoui, A., Zhao, W., Medina-Gomez, C. & 93 others, Bartz, T. M., Trompet, S., Lange, L. A., Raffield, L., Van Der Spek, A., Galesloot, T. E., Proitsi, P., Yanek, L., Bielak, L. F., Payton, A., Murgia, F., Concas, M. P., Biino, G., Tajuddin, S. M., Seppälä, I., Amin, N., Boerwinkle, E., Børglum, A. D., Campbell, A., Demerath, E. W., Demuth, I., Faul, J. D., Ford, I., Gialluisi, A., Gögele, M., Graff, M., Hingorani, A., Hottenga, J. J., Hougaard, D. M., Hurme, M. A., Ikram, M. A., Jylhä, M., Kuh, D., Ligthart, L., Lill, C. M., Lindenberger, U., Lumley, T., Mägi, R., Marques-Vidal, P., Medland, S. E., Milani, L., Nagy, R., Ollier, W. E. R., Peyser, P. A., Pramstaller, P. P., Ridker, P. M., Rivadeneira, F., Ruggiero, D., Saba, Y., Schmidt, R., Schmidt, H., Slagboom, P. E., Smith, B. H., Smith, J. A., Sotoodehnia, N., Steinhagen-Thiessen, E., Van Rooij, F. J. A., Verbeek, A. L., Vermeulen, S. H., Vollenweider, P., Wang, Y., Werge, T., Whitfield, J. B., Zonderman, A. B., Lehtimäki, T., Evans, M. K., Pirastu, M., Fuchsberger, C., Bertram, L., Pendleton, N., Kardia, S. L. R., Ciullo, M., Becker, D. M., Wong, A., Psaty, B. M., Van Duijn, C. M., Wilson, J. G., Jukema, J. W., Kiemeney, L., Uitterlinden, A. G., Franceschini, N., North, K. E., Weir, D. R., Metspalu, A., Boomsma, D. I., Hayward, C., Chasman, D., Martin, N. G., Sattar, N., Campbell, H., Esko, T., Kutalik, Z. & Wilson, J. F., Dec 1 2017, In : Nature Communications. 8, 1, 910.

Research output: Contribution to journalArticle

HLA-DRB1 Chains
genome
coronary artery disease
Meta-Analysis
Life Style

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

van Rooij, F. J. A., Qayyum, R., Smith, A. V., Zhou, Y., Trompet, S., Tanaka, T., Keller, M. F., Chang, L. C., Schmidt, H., Yang, M. L., Chen, M. H., Hayes, J., Johnson, A. D., Yanek, L., Mueller, C., Lange, L., Floyd, J. S., Ghanbari, M., Zonderman, A. B., Jukema, J. W. & 80 others, Hofman, A., van Duijn, C. M., Desch, K. C., Saba, Y., Ozel, A. B., Snively, B. M., Wu, J. Y., Schmidt, R., Fornage, M., Klein, R. J., Fox, C. S., Matsuda, K., Kamatani, N., Wild, P. S., Stott, D. J., Ford, I., Slagboom, P. E., Yang, J., Chu, A. Y., Lambert, A. J., Uitterlinden, A. G., Franco, O. H., Hofer, E., Ginsburg, D., Hu, B., Keating, B., Schick, U. M., Brody, J. A., Li, J. Z., Chen, Z., Zeller, T., Guralnik, J. M., Chasman, D. I., Peters, L. L., Kubo, M., Becker, D. M., Li, J., Eiriksdottir, G., Rotter, J. I., Levy, D., Grossmann, V., Patel, K. V., Chen, C. H., Ridker, P. M., Tang, H., Launer, L. J., Rice, K. M., Li-Gao, R., Ferrucci, L., Evans, M. K., Choudhuri, A., Trompouki, E., Abraham, B. J., Yang, S., Takahashi, A., Kamatani, Y., Kooperberg, C., Harris, T. B., Jee, S. H., Coresh, J., Tsai, F. J., Longo, D. L., Chen, Y. T., Felix, J. F., Yang, Q., Psaty, B. M., Boerwinkle, E., Becker, L., Mook-Kanamori, D. O., Wilson, J. G., Gudnason, V., O'Donnell, C. J., Dehghan, A., Cupples, L. A., Nalls, M. A., Morris, A. P., Okada, Y., Reiner, A. P., Zon, L. I. & Ganesh, S. K., Jan 5 2017, In : American Journal of Human Genetics. 100, 1, p. 51-63 13 p.

Research output: Contribution to journalArticle

Genetic Loci
Erythropoiesis
Genome-Wide Association Study
Meta-Analysis
Erythrocyte Indices
megakaryocytes
Induced Pluripotent Stem Cells
Megakaryocytes
Stem cells
transcriptomics

Novel genetic loci associated with hippocampal volume

Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., Desrivières, S., Vernooij, M. W., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S., Armstrong, N. J., Athanasiu, L. & 312 others, Axelsson, T., Beecham, A. H., Beiser, A., Bernard, M., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chen, Q., Ching, C. R. K., Chouraki, V., Cuellar-Partida, G., Crivello, F., Den Braber, A., Doan, N. T., Ehrlich, S., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Grimm, O., Griswold, M. E., Guadalupe, T., Gutman, B. A., Hass, J., Haukvik, U. K., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Jørgensen, K. N., Karbalai, N., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liewald, D. C. M., Lopez, L. M., Luciano, M., MacAre, C., Marquand, A. F., Matarin, M., Mather, K. A., Mattheisen, M., McKay, D. R., Milaneschi, Y., Muñoz Maniega, S., Nho, K., Nugent, A. C., Nyquist, P. A., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pirpamer, L., Pütz, B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Ropele, S., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Saremi, A., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Trompet, S., Vaidya, D., Van Der Grond, J., Van Der Lee, S. J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Wittfeld, K., Woldehawariat, G., Wolf, C., Wolfers, T., Yanek, L., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Craen, A. J. M., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Deary, I. J., Debette, S., Decarli, C., Delanty, N., Depondt, C., Destefano, A., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Enzinger, C., Erk, S., Espeseth, T., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Fornage, M., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Håberg, A. K., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Huentelman, M., Pol, H. E. H., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V., McDonald, C., McIntosh, A. M., McMahon, F. J., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schmidt, H., Schofield, P. R., Sigursson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J. C., Tsolaki, M., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Haren, N. E. M., Van 'T Ent, D., Van Tol, M. J., Vardarajan, B. N., Vellas, B., Veltman, D. J., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, R. H., Zonderman, A. B., Martin, N. G., Van Duijn, C. M., Wright, M. J., Longstreth, W. T., Schumann, G., Grabe, H. J., Franke, B., Launer, L. J., Medland, S. E., Seshadri, S., Thompson, P. M. & Ikram, M. A., Jan 18 2017, In : Nature Communications. 8, 13624.

Research output: Contribution to journalArticle

Genetic Loci
loci
Hippocampus
Genes
Episodic Memory

Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations

Liang, J., Le, T. H., Edwards, D. R. V., Tayo, B. O., Gaulton, K. J., Smith, J. A., Lu, Y., Jensen, R. A., Chen, G., Yanek, L., Schwander, K., Tajuddin, S. M., Sofer, T., Kim, W., Kayima, J., McKenzie, C. A., Fox, E., Nalls, M. A., Young, J. H., Sun, Y. V. & 59 others, Lane, J. M., Cechova, S., Zhou, J., Tang, H., Fornage, M., Musani, S. K., Wang, H., Lee, J., Adeyemo, A., Dreisbach, A. W., Forrester, T., Chu, P. L., Cappola, A., Evans, M. K., Morrison, A. C., Martin, L. W., Wiggins, K. L., Hui, Q., Zhao, W., Jackson, R. D., Ware, E. B., Faul, J. D., Reiner, A. P., Bray, M., Denny, J. C., Mosley, T. H., Palmas, W., Guo, X., Papanicolaou, G. J., Penman, A. D., Polak, J. F., Rice, K., Taylor, K. D., Boerwinkle, E., Bottinger, E. P., Liu, K., Risch, N., Hunt, S. C., Kooperberg, C., Zonderman, A. B., Laurie, C. C., Becker, D. M., Cai, J., Loos, R. J. F., Psaty, B. M., Weir, D. R., Kardia, S. L. R., Arnett, D. K., Won, S., Edwards, T. L., Redline, S., Cooper, R. S., Rao, D. C., Rotter, J. I., Rotimi, C., Levy, D., Chakravarti, A., Zhu, X. & Franceschini, N., May 1 2017, In : PLoS Genetics. 13, 5, e1006728.

Research output: Contribution to journalArticle

hypertension
Genome-Wide Association Study
ancestry
blood pressure
genome

Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

MEDIA Consortium, the FIND Consortium, the eMERGE Consortium, the DIAGRAM Consortium, The MuTHER Consortium, SIGMA T2D Consortium, the FIND Consortium, the eMERGE Consortium, the DIAGRAM Consortium, The MuTHER Consortium, SIGMA T2D Consortium, the eMERGE Consortium, the DIAGRAM Consortium, The MuTHER Consortium, SIGMA T2D Consortium, the DIAGRAM Consortium, The MuTHER Consortium, SIGMA T2D Consortium, The MuTHER Consortium, SIGMA T2D Consortium & 1 others, SIGMA T2D Consortium, Jun 29 2017, In : Cell. 170, 1, p. 199-212.e20

Research output: Contribution to journalArticle

Medical problems
Type 2 Diabetes Mellitus
Haplotypes
CD147 Antigens
Mexico

Whole exome sequencing in the Framingham heart study identifies rare variation in HYAL2 that influences platelet aggregation

Eicher, J. D., Chen, M. H., Pitsillides, A. N., Lin, H., Veeraraghavan, N., Brody, J. A., Metcalf, G. A., Muzny, D. M., Gibbs, R. A., Becker, D. M., Becker, L., Faraday, N., Mathias, R., Yanek, L., Boerwinkle, E., Adrienne Cupples, L. & Johnson, A. D., 2017, In : Thrombosis and Haemostasis. 117, 6, p. 1083-1092 10 p.

Research output: Contribution to journalArticle

Exome
Platelet Aggregation
Blood Platelets
Adenosine Diphosphate
Epinephrine
2016

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

De Vries, P. S., Chasman, D. I., Sabater-Lleal, M., Chen, M. H., Huffman, J. E., Steri, M., Tang, W., Teumer, A., Marioni, R. E., Grossmann, V., Hottenga, J. J., Trompet, S., Müller-Nurasyid, M., Zhao, J. H., Brody, J. A., Kleber, M. E., Guo, X., Wang, J. J., Auer, P. L., Attia, J. R. & 111 others, Yanek, L., Ahluwalia, T. S., Lahti, J., Venturini, C., Tanaka, T., Bielak, L. F., Joshi, P. K., Rocanin-Arjo, A., Kolcic, I., Navarro, P., Rose, L. M., Oldmeadow, C., Riess, H., Mazur, J., Basu, S., Goel, A., Yang, Q., Ghanbari, M., Gonnekewillemsen, Rumley, A., Fiorillo, E., De Craen, A. J. M., Grotevendt, A., Scott, R., Taylor, K. D., Delgado, G. E., Yao, J., Kifley, A., Kooperberg, C., Qayyum, R., Lopez, L., Berentzen, T. L., Räikkönen, K., Massimomangino, Bandinelli, S., Peyser, P. A., Wild, S., Trégouët, D. A., Wright, A. F., Marten, J., Zemunik, T., Morrison, A. C., Sennblad, B., Tofler, G., De Maat, M. P. M., De Geus, E. J. C., Lowe, G. D., Zoledziewska, M., Sattar, N., Binder, H., Völker, U., Waldenberger, M., Khaw, K. T., Mcknight, B., Huang, J., Jenny, N. S., Holliday, E. G., Qi, L., Mcevoy, M. G., Becker, D. M., Starr, J. M., Sarin, A. P., Hysi, P. G., Hernandez, D. G., Jhun, M. A., Campbell, H., Hamsten, A., Sarin, F., Mcardle, W. L., Eline Slagboom, P., Zeller, T., Koenig, W., Psaty, B., Haritunians, T., Liu, J., Palotie, A., Uitterlinden, A. G., Stott, D. J., Hofman, A., Franco, O. H., Polasek, O., Rudan, I., Morange, P. E., Wilson, J. F., Kardia, S. L. R., Ferrucci, L., Spector, T. D., Eriksson, J. G., Hansen, T., Deary, I. J., Becker, L., Scott, R. J., Mitchell, P., März, W., Wareham, N. J., Peters, A., Greinacher, A., Wild, P. S., Wouter Jukema, J., Boomsma, D. I., Hayward, C., Cucca, F., Tracy, R., Watkins, H., Reiner, A. P., Folsom, A. R., Ridker, P. M., O'Donnell, C. J., Smith, N. L., Strachan, D. P. & Dehghan, A., Jan 15 2016, In : Human Molecular Genetics. 25, 2, p. 358-370 13 p., ddv454.

Research output: Contribution to journalArticle

Fibrinogen
Meta-Analysis
X Chromosome
Genome
Genome-Wide Association Study

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

Chami, N., Chen, M. H., Slater, A. J., Eicher, J. D., Evangelou, E., Tajuddin, S. M., Love-Gregory, L., Kacprowski, T., Schick, U. M., Nomura, A., Giri, A., Lessard, S., Brody, J. A., Schurmann, C., Pankratz, N., Yanek, L., Manichaikul, A., Pazoki, R., Mihailov, E., Hill, W. D. & 93 others, Raffield, L. M., Burt, A., Bartz, T. M., Becker, D. M., Becker, L., Boerwinkle, E., Bork-Jensen, J., Bottinger, E. P., O'Donoghue, M. L., Crosslin, D. R., de Denus, S., Dubé, M. P., Elliott, P., Engström, G., Evans, M. K., Floyd, J. S., Fornage, M., Gao, H., Greinacher, A., Gudnason, V., Hansen, T., Harris, T. B., Hayward, C., Hernesniemi, J., Highland, H. M., Hirschhorn, J. N., Hofman, A., Irvin, M. R., Kähönen, M., Lange, E., Launer, L. J., Lehtimäki, T., Li, J., Liewald, D. C. M., Linneberg, A., Liu, Y., Lu, Y., Lyytikäinen, L. P., Mägi, R., Mathias, R., Melander, O., Metspalu, A., Mononen, N., Nalls, M. A., Nickerson, D. A., Nikus, K., O'Donnell, C. J., Orho-Melander, M., Pedersen, O., Petersmann, A., Polfus, L., Psaty, B. M., Raitakari, O. T., Raitoharju, E., Richard, M., Rice, K. M., Rivadeneira, F., Rotter, J. I., Schmidt, F., Smith, A. V., Starr, J. M., Taylor, K. D., Teumer, A., Thuesen, B. H., Torstenson, E. S., Tracy, R. P., Tzoulaki, I., Zakai, N. A., Vacchi-Suzzi, C., van Duijn, C. M., van Rooij, F. J. A., Cushman, M., Deary, I. J., Velez Edwards, D. R., Vergnaud, A. C., Wallentin, L., Waterworth, D. M., White, H. D., Wilson, J. G., Zonderman, A. B., Kathiresan, S., Grarup, N., Esko, T., Loos, R. J. F., Lange, L. A., Faraday, N., Abumrad, N. A., Edwards, T. L., Ganesh, S. K., Auer, P. L., Johnson, A. D., Reiner, A. P. & Lettre, G., Jul 7 2016, In : American Journal of Human Genetics. 99, 1, p. 8-21 14 p.

Research output: Contribution to journalArticle

Exome
Gene Frequency
Erythrocytes
Erythrocyte Indices
Hemoglobins
African Americans
Fats
Exercise
C-Reactive Protein
Observational Studies

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

Tajuddin, S. M., Schick, U. M., Eicher, J. D., Chami, N., Giri, A., Brody, J. A., Hill, W. D., Kacprowski, T., Li, J., Lyytikäinen, L. P., Manichaikul, A., Mihailov, E., O'Donoghue, M. L., Pankratz, N., Pazoki, R., Polfus, L. M., Smith, A. V., Schurmann, C., Vacchi-Suzzi, C., Waterworth, D. M. & 77 others, Evangelou, E., Yanek, L., Burt, A., Chen, M. H., van Rooij, F. J. A., Floyd, J. S., Greinacher, A., Harris, T. B., Highland, H. M., Lange, L. A., Liu, Y., Mägi, R., Nalls, M. A., Mathias, R., Nickerson, D. A., Nikus, K., Starr, J. M., Tardif, J. C., Tzoulaki, I., Velez Edwards, D. R., Wallentin, L., Bartz, T. M., Becker, L., Denny, J. C., Raffield, L. M., Rioux, J. D., Friedrich, N., Fornage, M., Gao, H., Hirschhorn, J. N., Liewald, D. C. M., Rich, S. S., Uitterlinden, A., Bastarache, L., Becker, D. M., Boerwinkle, E., de Denus, S., Bottinger, E. P., Hayward, C., Hofman, A., Homuth, G., Lange, E., Launer, L. J., Lehtimäki, T., Lu, Y., Metspalu, A., O'Donnell, C. J., Quarells, R. C., Richard, M., Torstenson, E. S., Taylor, K. D., Vergnaud, A. C., Zonderman, A. B., Crosslin, D. R., Deary, I. J., Dörr, M., Elliott, P., Evans, M. K., Gudnason, V., Kähönen, M., Psaty, B. M., Rotter, J. I., Slater, A. J., Dehghan, A., White, H. D., Ganesh, S. K., Loos, R. J. F., Esko, T., Faraday, N., Wilson, J. G., Cushman, M., Johnson, A. D., Edwards, T. L., Zakai, N. A., Lettre, G., Reiner, A. P. & Auer, P. L., Jul 7 2016, In : American Journal of Human Genetics. 99, 1, p. 22-39 18 p.

Research output: Contribution to journalArticle

Exome
Immune System Diseases
Leukocyte Count
Autoimmune Diseases
Leukocytes

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dörr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S. J., Isaacs, A., Jhun, M. A., Kavousi, M., Li-Gao, R., Lyytikäinen, L. P., Marioni, R. E., Schminke, U., Stitziel, N. O., Tada, H., Van Setten, J., Smith, A. V. & 80 others, Vojinovic, D., Yanek, L., Yao, J., Yerges-Armstrong, L. M., Amin, N., Baber, U., Borecki, I. B., Carr, J. J., Chen, Y. D. I., Cupples, L. A., De Jong, P. A., De Koning, H., De Vos, B. D., Demirkan, A., Fuster, V., Franco, O. H., Goodarzi, M. O., Harris, T. B., Heckbert, S. R., Heiss, G., Hoffmann, U., Hofman, A., Išgum, I., Jukema, J. W., Kähönen, M., Kardia, S. L. R., Kral, B. G., Launer, L. J., Massaro, J., Mehran, R., Mitchell, B. D., Mosley, T. H., De Mutsert, R., Newman, A. B., Nguyen, K. D., North, K. E., O'Connell, J. R., Oudkerk, M., Pankow, J. S., Peloso, G. M., Post, W. S., Province, M. A., Raffield, L. M., Raitakari, O. T., Reilly, D. F., Rivadeneira, F., Rosendaal, F., Sartori, S., Taylor, K. D., Teumer, A., Trompet, S., Turner, S. T., Uitterlinden, A. G., Vaidya, D., Van Der Lugt, A., Völker, U., Wardlaw, J. M., Wassel, C. L., Weiss, S., Wojczynski, M. K., Becker, D. M., Becker, L., Boerwinkle, E., Bowden, D. W., Deary, I. J., Dehghan, A., Felix, S. B., Gudnason, V., Lehtimäki, T., Mathias, R., Mook-Kanamori, D. O., Psaty, B. M., Rader, D. J., Rotter, J. I., Wilson, J. G., Van Duijn, C. M., Völzke, H., Kathiresan, S., Peyser, P. A. & O'Donnell, C. J., Dec 1 2016, In : Circulation: Cardiovascular Genetics. 9, 6, p. 511-520 10 p.

Research output: Contribution to journalArticle

Exome
Atherosclerosis
Coronary Vessels
Carotid Intima-Media Thickness
Coronary Disease

Novel genetic loci underlying human intracranial volume identified through genome-wide association

Adams, H. H. H., Hibar, D. P., Chouraki, V., Stein, J. L., Nyquist, P. A., Rentería, M. E., Trompet, S., Arias-Vasquez, A., Seshadri, S., Desrivières, S., Beecham, A. H., Jahanshad, N., Wittfeld, K., van der Lee, S. J., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S. & 322 others, Armstrong, N. J., Athanasiu, L., Axelsson, T., Beiser, A., Bernard, M., Bis, J. C., Blanken, L. M. E., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chauhan, G., Chen, Q., Ching, C. R. K., Cuellar-Partida, G., Braber, A. D., Doan, N. T., Ehrlich, S., Filippi, I., Ge, T., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Greven, C. U., Grimm, O., Griswold, M. E., Guadalupe, T., Hass, J., Haukvik, U. K., Hilal, S., Hofer, E., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liao, J., Liewald, D. C. M., Lopez, L. M., Luciano, M., Macare, C., Marquand, A., Matarin, M., Mather, K. A., Mattheisen, M., Mazoyer, B., McKay, D. R., McWhirter, R., Milaneschi, Y., Mirza-Schreiber, N., Muetzel, R. L., Maniega, S. M., Nho, K., Nugent, A. C., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pappa, I., Pirpamer, L., Pudas, S., Pütz, B., Rajan, K. B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Thomson, R., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Vaidya, D., van der Grond, J., van der Meer, D., van Donkelaar, M. M. J., van Eijk, K. R., van Erp, T. G. M., van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Woldehawariat, G., Wolf, C., Wolfers, T., Xu, B., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Aggarwal, N. T., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Chen, C., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., de Geus, E. J. C., de Jager, P. L., de Zubicaray, G. I., Delanty, N., Depondt, C., DeStefano, A. L., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Erk, S., Espeseth, T., Evans, D. A., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Grabe, H. J., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Pol, H. E. H., Ikeda, M., Ikram, M. K., Jr, C. R. J., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Jr, W. T. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, K. L., McMahon, F. J., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schofield, P. R., Sigurdsson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Srikanth, V., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Tiemeier, H., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., van der Brug, M., van der Lugt, A., van der Wee, N. J. A., van Duijn, C. M., van Haren, N. E. M., van ′t Ent, D., van Tol, M. J., Vardarajan, B. N., Veltman, D. J., Vernooij, M. W., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, H. R., Zonderman, A. B., Deary, I. J., DeCarli, C., Schmidt, H., Martin, N. G., de Craen, A. J. M., Wright, M. J., Launer, L. J., Schumann, G., Fornage, M., Franke, B., Debette, S., Medland, S. E., Ikram, M. A. & Thompson, P. M., Oct 3 2016, (Accepted/In press) In : Nature Neuroscience.

Research output: Contribution to journalArticle

Genetic Loci
Genome
Genome-Wide Association Study
Phosphatidylinositol 3-Kinases
Cognition

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

Eicher, J. D., Chami, N., Kacprowski, T., Nomura, A., Chen, M. H., Yanek, L., Tajuddin, S. M., Schick, U. M., Slater, A. J., Pankratz, N., Polfus, L., Schurmann, C., Giri, A., Brody, J. A., Lange, L. A., Manichaikul, A., Hill, W. D., Pazoki, R., Elliot, P., Evangelou, E. & 93 others, Tzoulaki, I., Gao, H., Vergnaud, A. C., Mathias, R., Becker, D. M., Becker, L., Burt, A., Crosslin, D. R., Lyytikäinen, L. P., Nikus, K., Hernesniemi, J., Kähönen, M., Raitoharju, E., Mononen, N., Raitakari, O. T., Lehtimäki, T., Cushman, M., Zakai, N. A., Nickerson, D. A., Raffield, L. M., Quarells, R., Willer, C. J., Peloso, G. M., Abecasis, G. R., Liu, D. J., Deloukas, P., Samani, N. J., Schunkert, H., Erdmann, J., Fornage, M., Richard, M., Tardif, J. C., Rioux, J. D., Dube, M. P., de Denus, S., Lu, Y., Bottinger, E. P., Loos, R. J. F., Smith, A. V., Harris, T. B., Launer, L. J., Gudnason, V., Velez Edwards, D. R., Torstenson, E. S., Liu, Y., Tracy, R. P., Rotter, J. I., Rich, S. S., Highland, H. M., Boerwinkle, E., Li, J., Lange, E., Wilson, J. G., Mihailov, E., Mägi, R., Hirschhorn, J., Metspalu, A., Esko, T., Vacchi-Suzzi, C., Nalls, M. A., Zonderman, A. B., Evans, M. K., Engström, G., Orho-Melander, M., Melander, O., O'Donoghue, M. L., Waterworth, D. M., Wallentin, L., White, H. D., Floyd, J. S., Bartz, T. M., Rice, K. M., Psaty, B. M., Starr, J. M., Liewald, D. C. M., Hayward, C., Deary, I. J., Greinacher, A., Völker, U., Thiele, T., Völzke, H., van Rooij, F. J. A., Uitterlinden, A. G., Franco, O. H., Dehghan, A., Edwards, T. L., Ganesh, S. K., Kathiresan, S., Faraday, N., Auer, P. L., Reiner, A. P., Lettre, G. & Johnson, A. D., Jul 7 2016, In : American Journal of Human Genetics. 99, 1, p. 40-55 16 p.

Research output: Contribution to journalArticle

Mean Platelet Volume
Platelet Count
Meta-Analysis
Blood Platelets
Blood Cells

SCARB1 Gene Variants Are Associated with the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a)

Yang, X., Sethi, A., Yanek, L., Knapper, C., Nordestgaard, B. G., Tybjærg-Hansen, A., Becker, D. M., Mathias, R., Remaley, A. T. & Becker, L., Oct 1 2016, In : Circulation: Cardiovascular Genetics. 9, 5, p. 408-418 11 p.

Research output: Contribution to journalArticle

Lipoprotein(a)
HDL Cholesterol
Phenotype
Genes
HDL Lipoproteins

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

Liu, C. T., Raghavan, S., Maruthur, N., Kabagambe, E. K., Hong, J., Ng, M. C. Y., Hivert, M. F., Lu, Y., An, P., Bentley, A. R., Drolet, A. M., Gaulton, K. J., Guo, X., Armstrong, L. L., Irvin, M. R., Li, M., Lipovich, L., Rybin, D. V., Taylor, K. D., Agyemang, C. & 95 others, Palmer, N. D., Cade, B. E., Chen, W. M., Dauriz, M., Delaney, J. A. C., Edwards, T. L., Evans, D. S., Evans, M. K., Lange, L. A., Leong, A., Liu, J., Liu, Y., Nayak, U., Patel, S. R., Porneala, B. C., Rasmussen-Torvik, L. J., Snijder, M. B., Stallings, S. C., Tanaka, T., Yanek, L., Zhao, W., Becker, D. M., Bielak, L. F., Biggs, M. L., Bottinger, E. P., Bowden, D. W., Chen, G., Correa, A., Couper, D. J., Crawford, D. C., Cushman, M., Eicher, J. D., Fornage, M., Franceschini, N., Fu, Y. P., Goodarzi, M. O., Gottesman, O., Hara, K., Harris, T. B., Jensen, R. A., Johnson, A. D., Jhun, M. A., Karter, A. J., Keller, M. F., Kho, A. N., Kizer, J. R., Krauss, R. M., Langefeld, C. D., Li, X., Liang, J., Liu, S., Lowe, W. L., Mosley, T. H., North, K. E., Pacheco, J. A., Peyser, P. A., Patrick, A. L., Rice, K. M., Selvin, E., Sims, M., Smith, J. A., Tajuddin, S. M., Vaidya, D., Wren, M. P., Yao, J., Zhu, X., Ziegler, J. T., Zmuda, J. M., Zonderman, A. B., Zwinderman, A. H., Adeyemo, A., Boerwinkle, E., Ferrucci, L., Hayes, M. G., Kardia, S. L. R., Miljkovic, I., Pankow, J. S., Rotimi, C. N., Sale, M. M., Wagenknecht, L. E., Arnett, D. K., Chen, Y. D. I., Nalls, M. A., Province, M. A., Kao, W. H. L., Siscovick, D. S., Psaty, B. M., Wilson, J. G., Loos, R. J. F., Dupuis, J., Rich, S. S., Florez, J. C., Rotter, J. I., Morris, A. P. & Meigs, J. B., Jul 7 2016, In : American Journal of Human Genetics. 99, 1, p. 56-75 20 p.

Research output: Contribution to journalArticle

Meta-Analysis
Fasting
Insulin
Glucose
Type 2 Diabetes Mellitus

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

Polfus, L. M., Khajuria, R. K., Schick, U. M., Pankratz, N., Pazoki, R., Brody, J. A., Chen, M. H., Auer, P. L., Floyd, J. S., Huang, J., Lange, L., van Rooij, F. J. A., Gibbs, R. A., Metcalf, G., Muzny, D., Veeraraghavan, N., Walter, K., Chen, L., Yanek, L., Becker, L. & 36 others, Peloso, G. M., Wakabayashi, A., Kals, M., Metspalu, A., Esko, T., Fox, K., Wallace, R., Franceshini, N., Matijevic, N., Rice, K. M., Bartz, T. M., Lyytikäinen, L. P., Kähönen, M., Lehtimäki, T., Raitakari, O. T., Li-Gao, R., Mook-Kanamori, D. O., Lettre, G., van Duijn, C. M., Franco, O. H., Rich, S. S., Rivadeneira, F., Hofman, A., Uitterlinden, A. G., Wilson, J. G., Psaty, B. M., Soranzo, N., Dehghan, A., Boerwinkle, E., Zhang, X., Johnson, A. D., O'Donnell, C. J., Johnsen, J. M., Reiner, A. P., Ganesh, S. K. & Sankaran, V. G., Aug 4 2016, In : American Journal of Human Genetics. 99, 2, p. 481-488 8 p.

Research output: Contribution to journalArticle

Exome
Hematopoiesis
Hematopoietic Stem Cells
Blood Cells
Clustered Regularly Interspaced Short Palindromic Repeats
2015

Age differences in periventricular and deep white matter lesions

Nyquist, P. A., Bilgel, M., Gottesman, R. F., Yanek, L., Moy, T. F., Becker, L., Cuzzocreo, J. L., Prince, J. L., Wasserman, B. A., Yousem, D. M., Becker, D. M., Kral, B. G. & Vaidya, D., Apr 1 2015, In : Neurobiology of Aging. 36, 4, p. 1653-1658 6 p.

Research output: Contribution to journalArticle

Coronary Artery Disease
White Matter
African Americans
Stroke
Magnetic Resonance Imaging

Common genetic variants influence human subcortical brain structures

Hibar, D. P., Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., Jahanshad, N., Toro, R., Wittfeld, K., Abramovic, L., Andersson, M., Aribisala, B. S., Armstrong, N. J., Bernard, M., Bohlken, M. M., Boks, M. P., Bralten, J., Brown, A. A., Mallar Chakravarty, M., Chen, Q., Ching, C. R. K. & 267 others, Cuellar-Partida, G., Den Braber, A., Giddaluru, S., Goldman, A. L., Grimm, O., Guadalupe, T., Hass, J., Woldehawariat, G., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Olde Loohuis, L. M., Luciano, M., MacAre, C., Mather, K. A., Mattheisen, M., Milaneschi, Y., Nho, K., Papmeyer, M., Ramasamy, A., Risacher, S. L., Roiz-Santiañez, R., Rose, E. J., Salami, A., Sämann, P. G., Schmaal, L., Schork, A. J., Shin, J., Strike, L. T., Teumer, A., Van Donkelaar, M. M. J., Van Eijk, K. R., Walters, R. K., Westlye, L. T., Whelan, C. D., Winkler, A. M., Zwiers, M. P., Alhusaini, S., Athanasiu, L., Ehrlich, S., Hakobjan, M. M. H., Hartberg, C. B., Haukvik, U. K., Heister, A. J. G. A. M., Hoehn, D., Kasperaviciute, D., Liewald, D. C. M., Lopez, L. M., Makkinje, R. R. R., Matarin, M., Naber, M. A. M., Reese McKay, D., Needham, M., Nugent, A. C., Pütz, B., Royle, N. A., Shen, L., Sprooten, E., Trabzuni, D., Van Der Marel, S. S. L., Van Hulzen, K. J. E., Walton, E., Wolf, C., Almasy, L., Ames, D., Arepalli, S., Assareh, A. A., Bastin, M. E., Brodaty, H., Bulayeva, K. B., Carless, M. A., Cichon, S., Corvin, A., Curran, J. E., Czisch, M., De Zubicaray, G. I., Dillman, A., Duggirala, R., Dyer, T. D., Erk, S., Fedko, I. O., Ferrucci, L., Foroud, T. M., Fox, P. T., Fukunaga, M., Raphael Gibbs, J., Göring, H. H. H., Green, R. C., Guelfi, S., Hansell, N. K., Hartman, C. A., Hegenscheid, K., Heinz, A., Hernandez, D. G., Heslenfeld, D. J., Hoekstra, P. J., Holsboer, F., Homuth, G., Hottenga, J. J., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Kanai, R., Keil, M., Kent, J. W., Kochunov, P., Kwok, J. B., Lawrie, S. M., Liu, X., Longo, D. L., McMahon, K. L., Meisenzahl, E., Melle, I., Mohnke, S., Montgomery, G. W., Mostert, J. C., Mühleisen, T. W., Nalls, M. A., Nichols, T. E., Nilsson, L. G., Nöthen, M. M., Ohi, K., Olvera, R. L., Perez-Iglesias, R., Bruce Pike, G., Potkin, S. G., Reinvang, I., Reppermund, S., Rietschel, M., Romanczuk-Seiferth, N., Rosen, G. D., Rujescu, D., Schnell, K., Schofield, P. R., Smith, C., Steen, V. M., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J. C., Turner, J. A., Valdés Hernández, M. C., Van 'T Ent, D., Van Der Brug, M., Van Der Wee, N. J. A., Van Tol, M. J., Veltman, D. J., Wassink, T. H., Westman, E., Zielke, R. H., Zonderman, A. B., Ashbrook, D. G., Hager, R., Lu, L., McMahon, F. J., Morris, D. W., Williams, R. W., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Cahn, W., Calhoun, V. D., Cavalleri, G. L., Crespo-Facorro, B., Dale, A. M., Davies, G. E., Delanty, N., Depondt, C., Djurovic, S., Drevets, W. C., Espeseth, T., Gollub, R. L., Ho, B. C., Hoffmann, W., Hosten, N., Kahn, R. S., Le Hellard, S., Meyer-Lindenberg, A., Müller-Myhsok, B., Nauck, M., Nyberg, L., Pandolfo, M., Penninx, B. W. J. H., Roffman, J. L., Sisodiya, S. M., Smoller, J. W., Van Bokhoven, H., Van Haren, N. E. M., Völzke, H., Walter, H., Weiner, M. W., Wen, W., White, T., Agartz, I., Andreassen, O. A., Blangero, J., Boomsma, D. I., Brouwer, R. M., Cannon, D. M., Cookson, M. R., De Geus, E. J. C., Deary, I. J., Donohoe, G., Fernández, G., Fisher, S. E., Francks, C., Glahn, D. C., Grabe, H. J., Gruber, O., Hardy, J., Hashimoto, R., Hulshoff Pol, H. E., Jönsson, E. G., Kloszewska, I., Lovestone, S., Mattay, V., Mecocci, P., McDonald, C., McIntosh, A. M., Ophoff, R. A., Paus, T., Pausova, Z., Ryten, M., Sachdev, P. S., Saykin, A. J., Simmons, A., Singleton, A., Soininen, H., Wardlaw, J. M., Weale, M. E., Weinberger, D., Adams, H. H. H., Launer, L. J., Seiler, S., Schmidt, R., Chauhan, G., Satizabal, C. L., Becker, J. T., Yanek, L., Van Der Lee, S. J., Ebling, M., Fischl, B., Longstreth, W. T., Greve, D., Schmidt, H., Nyquist, P. A., Vinke, L. N., Van Duijn, C. M., Xue, L., Mazoyer, B., Bis, J. C., Gudnason, V., Seshadri, S., Ikram, M. A., Martin, N. G., Wright, M. J., Schumann, G., Franke, B., Thompson, P. M. & Medland, S. E., Apr 9 2015, In : Nature. 520, 7546, p. 224-229 6 p.

Research output: Contribution to journalArticle

Putamen
Brain
Developmental Genes
Transport Vesicles
Caudate Nucleus

Directional dominance on stature and cognition in diverse human populations

The Bio Bank Japan Project & Ferrucci, L., Jul 23 2015, In : Nature. 523, 7561, p. 459-462 4 p.

Research output: Contribution to journalArticle

Cognition
Genome
Population
Aptitude
Inbreeding

Effect of white matter lesions on manual dexterity in healthy middle-aged persons

Nyquist, P. A., Yanek, L., Bilgel, M., Cuzzocreo, J. L., Becker, L., Chevalier-Davis, K., Yousem, D. M., Prince, J. L., Kral, B. G., Vaidya, D. & Becker, D. M., May 12 2015, In : Neurology. 84, 19, p. 1920-1926 7 p.

Research output: Contribution to journalArticle

Sex Education
Vascular Diseases
Coronary Artery Disease
Brain
Cerebrovascular Disorders

Genome-wide association study of platelet aggregation in African Americans

Qayyum, R., Becker, L., Becker, D. M., Faraday, N., Yanek, L., Leal, S. M., Shaw, C., Mathias, R., Suktitipat, B. & Bray, P. F., May 30 2015, In : BMC Genetics. 16, 1, 58.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Platelet Aggregation
African Americans
Adenosine Diphosphate
Single Nucleotide Polymorphism
Cyclooxygenase 1
Acute Coronary Syndrome
Platelets
Platelet Aggregation
Collagen

Lean Mass and Fat Mass as Contributors to Physical Fitness in an Overweight and Obese African American Population

Yanek, L., Vaidya, D., Kral, B. G., Dobrosielski, D. A., Moy, T. F., Stewart, K. & Becker, D. M., Mar 1 2015, In : Ethnicity and Disease. 25, 2, p. 214-219 6 p.

Research output: Contribution to journalArticle

Physical Fitness
African Americans
Fats
Body Mass Index
Cross-Sectional Studies