Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 10 Similar Profiles
Induced Pluripotent Stem Cells Medicine & Life Sciences
Stem cells Chemical Compounds
Hematopoietic Stem Cells Medicine & Life Sciences
Pluripotent Stem Cells Medicine & Life Sciences
Stem Cells Medicine & Life Sciences
Genes Medicine & Life Sciences
Transgenes Medicine & Life Sciences
Gene Expression Medicine & Life Sciences

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Research Output 1989 2018

Conditional gene knockout and reconstitution in human iPSCs with an inducible Cas9 system

Wu, M., Liu, S., Gao, Y., Bai, H., Machairaki, V., Li, G., Chen, T. & Cheng, L. May 1 2018 In : Stem Cell Research. 29, p. 6-14 9 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Gene Knockout Techniques
Guide RNA
Gene Order
Transgenes

Human NOTCH4 is a key target of RUNX1 in megakaryocytic differentiation

Li, Y., Jin, C., Bai, H., Gao, Y., Sun, S., Chen, L., Qin, L., Liu, P. P., Cheng, L. & Wang, Q. F. Jan 11 2018 In : Blood. 131, 2, p. 191-201 11 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Megakaryocytes
Platelets
Stem cells
Blood Platelets

A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model

Yuan, X., Li, Z., Baines, A. C., Gavriilaki, E., Ye, Z., Wen, Z., Braunstein, E. M., Biesecker, L. G., Cheng, L., Dong, X. & Brodsky, R. A. Apr 1 2017 In : PLoS ONE. 12, 4, e0174074

Research output: Contribution to journalArticle

Glycosylphosphatidylinositols
Neurons
Toxicity
complement
neurodevelopment

A Universal Approach to Correct Various HBB Gene Mutations in Human Stem Cells for Gene Therapy of Beta-Thalassemia and Sickle Cell Disease

Cai, L., Bai, H., Mahairaki, V., Gao, Y., He, C., Wen, Y., Jin, Y. C., Wang, Y., Pan, R. L., Qasba, A., Ye, Z. & Cheng, L. Jan 1 2017 (Accepted/In press) In : Stem Cells Translational Medicine.

Research output: Contribution to journalArticle

beta-Thalassemia
Sickle Cell Anemia
Cell- and Tissue-Based Therapy
Genetic Therapy
Stem Cells

Generation of human iPSCs from an essential thrombocythemia patient carrying a V501L mutation in the MPL gene

Liu, S., Ye, Z., Gao, Y., He, C., Williams, D. W., Moliterno, A., Spivak, J., Huang, H. & Cheng, L. Jan 1 2017 In : Stem Cell Research. 18, p. 57-59 3 p.

Research output: Contribution to journalArticle

Essential Thrombocythemia
Induced Pluripotent Stem Cells
Mutation
Thrombopoietin Receptors
Genes