Lindsey Hayes

Assistant Professor

20042019
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Fingerprint Dive into the research topics where Lindsey Hayes is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 9 Similar Profiles
Amyotrophic Lateral Sclerosis Medicine & Life Sciences
Axons Medicine & Life Sciences
Motor Neurons Medicine & Life Sciences
Dipeptides Medicine & Life Sciences
Oxidative Stress Medicine & Life Sciences
Knockout Mice Medicine & Life Sciences
Motor Neuron Disease Medicine & Life Sciences
Denervation Medicine & Life Sciences

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Research Output 2004 2019

CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation

Cheng, W., Wang, S., Zhang, Z., Morgens, D. W., Hayes, L. R., Lee, S., Portz, B., Xie, Y., Nguyen, B. V., Haney, M. S., Yan, S., Dong, D., Coyne, A. N., Yang, J., Xian, F., Cleveland, D. W., Qiu, Z., Rothstein, J. D., Shorter, J., Gao, F. B. & 2 others, Bassik, M. C. & Sun, S., Dec 4 2019, In : Neuron. 104, 5, p. 885-898.e8

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
RNA Helicases
Dipeptides
RNA
Antisense RNA

Distal denervation in the SOD1 knockout mouse correlates with loss of mitochondria at the motor nerve terminal

Hayes, L., Asress, S. A., Li, Y., Galkin, A., Stepanova, A., Kawamata, H., Manfredi, G. & Glass, J. D., Aug 1 2019, In : Experimental Neurology. 318, p. 251-257 7 p.

Research output: Contribution to journalArticle

Denervation
Knockout Mice
Mitochondria
Neuromuscular Junction
Axons

C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2α phosphorylation

Cheng, W., Wang, S., Mestre, A. A., Fu, C., Makarem, A., Xian, F., Hayes, L., Lopez-Gonzalez, R., Drenner, K., Jiang, J., Cleveland, D. W. & Sun, S., Dec 1 2018, In : Nature Communications. 9, 1, 02495.

Research output: Contribution to journalArticle

Eukaryotic Initiation Factor-2
phosphorylation
Phosphorylation
Dipeptides
caps

Adult intestinal colonization botulism mimicking brain death

Freund, B., Hayes, L., Rivera Lara, L., Sumner, C., Chaudhry, V., Chatham-Stephens, K., Benedict, K., Kalb, S., Blythe, D., Brooks, R. & Probasco, J. C., 2017, (Accepted/In press) In : Muscle and Nerve.

Research output: Contribution to journalArticle

Botulism
Brain Death

Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis

Gendron, T. F., Chew, J., Stankowski, J. N., Hayes, L., Zhang, Y. J., Prudencio, M., Carlomagno, Y., Daughrity, L. M., Jansen-West, K., Perkerson, E. A., O'Raw, A., Cook, C., Pregent, L., Belzil, V., Van Blitterswijk, M., Tabassian, L. J., Lee, C. W., Yue, M., Tong, J., Song, Y. & 59 others, Castanedes-Casey, M., Rousseau, L., Phillips, V., Dickson, D. W., Rademakers, R., Fryer, J. D., Rush, B. K., Pedraza, O., Caputo, A. M., Desaro, P., Palmucci, C., Robertson, A., Heckman, M. G., Diehl, N. N., Wiggs, E., Tierney, M., Braun, L., Farren, J., Lacomis, D., Ladha, S., Fournier, C. N., McCluskey, L. F., Elman, L. B., Toledo, J. B., McBride, J. D., Tiloca, C., Morelli, C., Poletti, B., Solca, F., Prelle, A., Wuu, J., Jockel-Balsarotti, J., Rigo, F., Ambrose, C., Datta, A., Yang, W., Raitcheva, D., Antognetti, G., McCampbell, A., Van Swieten, J. C., Miller, B. L., Boxer, A. L., Brown, R. H., Bowser, R., Miller, T. M., Trojanowski, J. Q., Grossman, M., Berry, J. D., Hu, W. T., Ratti, A., Traynor, B. J., Disney, M. D., Benatar, M., Silani, V., Glass, J. D., Floeter, M. K., Rothstein, J. D., Boylan, K. B. & Petrucelli, L., Mar 29 2017, In : Science Translational Medicine. 9, 383, eaai7866.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
RNA
Proteins
Antisense Oligonucleotides
Therapeutics