Lewis Romer

Professor

1978 …2020

Research output per year

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Research Output

  • 72 Article
  • 3 Conference contribution
  • 2 Comment/debate
  • 2 Review article
2020

3D printing and characterization of a soft and biostable elastomer with high flexibility and strength for biomedical applications

Bachtiar, E. O., Erol, O., Millrod, M., Tao, R., Gracias, D. H., Romer, L. H. & Kang, S. H., Apr 2020, In : Journal of the Mechanical Behavior of Biomedical Materials. 104, 103649.

Research output: Contribution to journalArticle

A microfluidic device for trapping and dynamic interrogation of arterioles

Chen, X., Pagaduan, J. V., Bhatta, A., Gracias, D. H. & Romer, L., Jan 1 2020, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017. Chemical and Biological Microsystems Society, p. 1112-1113 2 p. (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

A microtrap platform to investigate single cell mechanics

Jin, Q., Pahapale, G., Bhatta, A., Dai, A., Romer, L. & Gracias, D. H., Jan 1 2020, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017. Chemical and Biological Microsystems Society, p. 908-909 2 p. (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

Weiss, S. L., Peters, M. J., Alhazzani, W., Agus, M. S. D., Flori, H. R., Inwald, D. P., Nadel, S., Schlapbach, L. J., Tasker, R. C., Argent, A. C., Brierley, J., Carcillo, J., Carrol, E. D., Carroll, C. L., Cheifetz, I. M., Choong, K., Cies, J. J., Cruz, A. T., De Luca, D., Deep, A. & 31 others, Faust, S. N., De Oliveira, C. F., Hall, M. W., Ishimine, P., Javouhey, E., Joosten, K. F. M., Joshi, P., Karam, O., Kneyber, M. C. J., Lemson, J., MacLaren, G., Mehta, N. M., Møller, M. H., Newth, C. J. L., Nguyen, T. C., Nishisaki, A., Nunnally, M. E., Parker, M. M., Paul, R. M., Randolph, A. G., Ranjit, S., Romer, L. H., Scott, H. F., Tume, L. N., Verger, J. T., Williams, E. A., Wolf, J., Wong, H. R., Zimmerman, J. J., Kissoon, N. & Tissieres, P., Feb 1 2020, In : Intensive Care Medicine. 46

Research output: Contribution to journalArticle

Open Access

Executive summary: Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

Weiss, S. L., Peters, M. J., Alhazzani, W., Agus, M. S. D., Flori, H. R., Inwald, D. P., Nadel, S., Schlapbach, L. J., Tasker, R. C., Argent, A. C., Brierley, J., Carcillo, J., Carrol, E. D., Carroll, C. L., Cheifetz, I. M., Choong, K., Cies, J. J., Cruz, A. T., de Luca, D., Deep, A. & 31 others, Faust, S. N., de Oliveira, C. F., Hall, M. W., Ishimine, P., Javouhey, E., Joosten, K. F. M., Joshi, P., Karam, O., Kneyber, M. C. J., Lemson, J., MacLaren, G., Mehta, N. M., Møller, M. H., Newth, C. J. L., Nguyen, T. C., Nishisaki, A., Nunnally, M. E., Parker, M. M., Paul, R. M., Randolph, A. G., Ranjit, S., Romer, L. H., Scott, H. F., Tume, L. N., Verger, J. T., Williams, E. A., Wolf, J., Wong, H. R., Zimmerman, J. J., Kissoon, N. & Tissieres, P., Feb 1 2020, In : Pediatric Critical Care Medicine. p. 186-195 10 p.

Research output: Contribution to journalArticle

Open Access

Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

Weiss, S. L., Peters, M. J., Alhazzani, W., Agus, M. S. D., Flori, H. R., Inwald, D. P., Nadel, S., Schlapbach, L. J., Tasker, R. C., Argent, A. C., Brierley, J., Carcillo, J., Carrol, E. D., Carroll, C. L., Cheifetz, I. M., Choong, K., Cies, J. J., Cruz, A. T., De Luca, D., Deep, A. & 31 others, Faust, S. N., De Oliveira, C. F., Hall, M. W., Ishimine, P., Javouhey, E., Joosten, K. F. M., Joshi, P., Karam, O., Kneyber, M. C. J., Lemson, J., MacLaren, G., Mehta, N. M., Møller, M. H., Newth, C. J. L., Nguyen, T. C., Nishisaki, A., Nunnally, M. E., Parker, M. M., Paul, R. M., Randolph, A. G., Ranjit, S., Romer, L. H., Scott, H. F., Tume, L. N., Verger, J. T., Williams, E. A., Wolf, J., Wong, H. R., Zimmerman, J. J., Kissoon, N. & Tissieres, P., Feb 1 2020, In : Intensive Care Medicine. 46, p. 10-67 58 p.

Research output: Contribution to journalArticle

Open Access

Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

Weiss, S. L., Peters, M. J., Alhazzani, W., Agus, M. S. D., Flori, H. R., Inwald, D. P., Nadel, S., Schlapbach, L. J., Tasker, R. C., Argent, A. C., Brierley, J., Carcillo, J., Carrol, E. D., Carroll, C. L., Cheifetz, I. M., Choong, K., Cies, J. J., Cruz, A. T., de Luca, D., Deep, A. & 31 others, Faust, S. N., de Oliveira, C. F., Hall, M. W., Ishimine, P., Javouhey, E., Joosten, K. F. M., Joshi, P., Karam, O., Kneyber, M. C. J., Lemson, J., MacLaren, G., Mehta, N. M., Møller, M. H., Newth, C. J. L., Nguyen, T. C., Nishisaki, A., Nunnally, M. E., Parker, M. M., Paul, R. M., Randolph, A. G., Ranjit, S., Romer, L. H., Scott, H. F., Tume, L. N., Verger, J. T., Williams, E. A., Wolf, J., Wong, H. R., Zimmerman, J. J., Kissoon, N. & Tissieres, P., Feb 1 2020, In : Pediatric Critical Care Medicine. p. E52-E106

Research output: Contribution to journalArticle

Open Access
2019

Direct Ink Writing of Poly(tetrafluoroethylene) (PTFE) with Tunable Mechanical Properties

Jiang, Z., Erol, O., Chatterjee, D., Xu, W., Hibino, N., Romer, L., Kang, S. H. & Gracias, D. H., Aug 7 2019, In : ACS Applied Materials and Interfaces. 11, 31, p. 28289-28295 7 p.

Research output: Contribution to journalArticle

Dual-Gel 4D Printing of Bioinspired Tubes

Liu, J., Erol, O., Pantula, A., Liu, W., Jiang, Z., Kobayashi, K., Chatterjee, D., Hibino, N., Romer, L., Kang, S. H., Nguyen, T. D. & Gracias, D. H., Feb 27 2019, In : ACS Applied Materials and Interfaces. 11, 8, p. 8492-8498 7 p.

Research output: Contribution to journalArticle

Hierarchically Curved Gelatin for 3D Biomimetic Cell Culture

Pahapale, G. J., Gao, S., Romer, L. H. & Gracias, D. H., Dec 16 2019, In : ACS Applied Bio Materials. 2, 12, p. 6004-6011 8 p.

Research output: Contribution to journalArticle

Inositol hexakisphosphate kinase 3 promotes focal adhesion turnover via interactions with dynein intermediate chain 2

Rojas, T., Cheng, W., Gao, Z., Liu, X., Wang, Y., Malla, A. P., Chin, A. C., Romer, L., Snyder, S. H. & Fu, C., Feb 19 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 8, p. 3278-3287 10 p.

Research output: Contribution to journalArticle

2018

3D Hybrid Small Scale Devices

Pagaduan, J. V., Bhatta, A., Romer, L. & Gracias, D. H., Jan 1 2018, (Accepted/In press) In : Small.

Research output: Contribution to journalArticle

Opsin 3 and 4 mediate light-induced pulmonary vasorelaxation that is potentiated by G protein-coupled receptor kinase 2 inhibition

Barreto Ortiz, S., Hori, D., Nomura, Y., Yun, X., Jiang, H., Yong, H., Chen, J., Paek, S., Pandey, D., Sikka, G., Bhatta, A., Gillard, A., Steppan, J., Kim, J. H., Adachi, H., Barodka, V., Romer, L., An, S., Shimoda, L., Santhanam, L. & 1 others, Berkowitz, D. E., Jan 1 2018, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 314, 1, p. L93-L106

Research output: Contribution to journalArticle

Perioperative events in children with pulmonary hypertension undergoing non-cardiac procedures

Bernier, M., Jacob, A. I., Collaco, M., McGrath-Morrow, S. A., Romer, L. & Unegbu, C. C., Jan 1 2018, In : Pulmonary Circulation. 8, 1

Research output: Contribution to journalArticle

2017

Cystathionine γ-lyase protects vascular endothelium: A role for inhibition of histone deacetylase 6

Leucker, T., Nomura, Y., Kim, J. H., Bhatta, A., Wang, V., Wecker, A., Jandu, S., Santhanam, L., Berkowitz, D. E., Romer, L. & Pandey, D., 2017, In : American Journal of Physiology - Heart and Circulatory Physiology. 312, 4, p. H711-H720

Research output: Contribution to journalArticle

Evaluation and Management of Pulmonary Hypertension in Children with Bronchopulmonary Dysplasia

Krishnan, U., Feinstein, J. A., Adatia, I., Austin, E. D., Mullen, M. P., Hopper, R. K., Hanna, B., Romer, L., Keller, R. L., Fineman, J., Steinhorn, R., Kinsella, J. P., Ivy, D. D., Rosenzweig, E. B., Raj, U., Humpl, T. & Collaco, M., Feb 24 2017, (Accepted/In press) In : Journal of Pediatrics.

Research output: Contribution to journalArticle

Pulmonary hypertension therapy and a systematic review of efficacy and safety of PDE-5 inhibitors

Unegbu, C., Noje, C., Coulson, J. D., Segal, J. & Romer, L., Mar 1 2017, In : Pediatrics. 139, 3, e20161450.

Research output: Contribution to journalReview article

2016

A self-folding hydrogel in vitro model for ductal carcinoma

Kwag, H. R., Serbo, J. V., Korangath, P., Sukumar, S., Romer, L. & Gracias, D. H., Apr 1 2016, In : Tissue Engineering - Part C: Methods. 22, 4, p. 398-407 10 p.

Research output: Contribution to journalArticle

Patterning of Fibroblast and Matrix Anisotropy within 3D Confinement is Driven by the Cytoskeleton

Serbo, J. V., Kuo, S., Lewis, S., Lehmann, M., Li, J., Gracias, D. H. & Romer, L. H., Jan 1 2016, In : Advanced Healthcare Materials. 5, 1, p. 146-158 13 p.

Research output: Contribution to journalArticle

2015

NEDDylation promotes endothelial dysfunction: A role for HDAC2

Pandey, D., Hori, D., Kim, J. H., Bergman, Y., Berkowitz, D. E. & Romer, L. H., Apr 1 2015, In : Journal of Molecular and Cellular Cardiology. 81, p. 18-22 5 p.

Research output: Contribution to journalArticle

Oriented matrix promotes directional tubulogenesis

Soucy, P. A., Hoh, M., Heinz, W., Hoh, J. & Romer, L., Jan 1 2015, In : Acta Biomaterialia. 11, 1, p. 264-273 10 p.

Research output: Contribution to journalArticle

Trends in hospitalization for pediatric pulmonary hypertension

Maxwell, B. G., Nies, M. K., Ajuba-Iwuji, C. C., Coulson, J. D. & Romer, L. H., Aug 1 2015, In : Pediatrics. 136, 2, p. 241-250 10 p.

Research output: Contribution to journalArticle

2014

Endothelial Matrix Assembly during Capillary Morphogenesis: Insights from Chimeric TagRFP-Fibronectin Matrix

Chang, F., Lemmon, C. A., Nilaratanakul, V., Rotter, V. & Romer, L., Nov 19 2014, In : Journal of Histochemistry and Cytochemistry. 62, 11, p. 774-790 17 p.

Research output: Contribution to journalArticle

OxLDL Triggers Retrograde Translocation of Arginase2 in Aortic Endothelial Cells via ROCK and Mitochondrial Processing Peptidase

Pandey, D., Bhunia, A., Oh, Y. J., Chang, F., Bergman, Y., Kim, J. H., Serbo, J., Boronina, T. N., Cole, R. N., Van Eyk, J., Remaley, A. T., Berkowitz, D. E. & Romer, L. H., Aug 1 2014, In : Circulation research. 115, 4, p. 450-459 10 p.

Research output: Contribution to journalArticle

Transcriptional regulation of endothelial arginase 2 by histone deacetylase 2

Pandey, D., Sikka, G., Bergman, Y., Kim, J. H., Ryoo, S., Romer, L. & Berkowitz, D., Jul 2014, In : Arteriosclerosis, thrombosis, and vascular biology. 34, 7, p. 1556-1566 11 p.

Research output: Contribution to journalArticle

Understanding nanotopography induced stem cell differentiation: A focus on focal adhesion Kinase

Teo, B. K. K., Wong, S. T., Lim, C. K., Kung, T. Y. S., Yap, C. H., Ramgopal, Y., Romer, L. H. & Yim, E. K. F., Jan 1 2014, The 15th International Conference on Biomedical Engineering, ICBME 2013. Goh, J. (ed.). Springer Verlag, p. 36-39 4 p. (IFMBE Proceedings; vol. 43).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2013

Arginase II: atherogenesis beyond enzyme activity.

Pandey, D., Romer, L. & Berkowitz, D. E., Aug 2013, In : Journal of the American Heart Association. 2, 4, p. e000392

Research output: Contribution to journalComment/debate

Open Access

Nanotopography modulates mechanotransduction of stem cells and induces differentiation through focal adhesion kinase

Teo, B. K. K., Wong, S. T., Lim, C. K., Kung, T. Y. S., Yap, C. H., Ramagopal, Y., Romer, L. H. & Yim, E. K. F., Jun 25 2013, In : ACS Nano. 7, 6, p. 4785-4798 14 p.

Research output: Contribution to journalArticle

2012

Frontiers in pulmonary hypertension in infants and children with bronchopulmonary dysplasia

Collaco, J. M., Romer, L. H., Stuart, B. D., Coulson, J. D., Everett, A. D., Lawson, E. E., Brenner, J. I., Brown, A. T., Nies, M. K., Sekar, P., Nogee, L. M. & McGrath-Morrow, S. A., Oct 1 2012, In : Pediatric pulmonology. 47, 11, p. 1042-1053 12 p.

Research output: Contribution to journalArticle

Inhaled epoprostenol therapy for pulmonary hypertension: Improves oxygenation index more consistently in neonates than in older children

Brown, A. T., Gillespie, J. V., Miquel-Verges, F., Holmes, K., Ravekes, W., Spevak, P., Brady, K., Blaine Easley, R., Christopher Golden, W., McNamara, L., Veltri, M. A., Lehmann, C. U., McMillan, K. N., Schwartz, J. M. & Romer, L. H., Jan 2012, In : Pulmonary Circulation. 2, 1, p. 61-66 6 p.

Research output: Contribution to journalArticle

2011

Microelastic properties of lung cell-derived extracellular matrix

Soucy, P. A., Werbin, J., Heinz, W., Hoh, J. H. & Romer, L. H., Jan 1 2011, In : Acta Biomaterialia. 7, 1, p. 96-105 10 p.

Research output: Contribution to journalArticle

OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling

Ryoo, S., Bhunia, A., Chang, F., Shoukas, A., Berkowitz, D. E. & Romer, L. H., Feb 1 2011, In : Atherosclerosis. 214, 2, p. 279-287 9 p.

Research output: Contribution to journalArticle

Pediatric residents do not feel prepared for the most unsettling situations they face in the pediatric intensive care unit.

Yang, C. P., Leung, J., Hunt, E. A., Serwint, J., Norvell, M., Keene, E. A. & Romer, L. H., Jan 2011, In : Journal of palliative medicine. 14, 1, p. 25-30 6 p.

Research output: Contribution to journalArticle

Tyrosine phosphorylation of rac1: A role in regulation of cell spreading

Chang, F., Lemmon, C., Lietha, D., Eck, M. & Romer, L., Dec 6 2011, In : PloS one. 6, 12, e28587.

Research output: Contribution to journalArticle

2010

A predictive model of cell traction forces based on cell geometry

Lemmon, C. A. & Romer, L. H., Nov 3 2010, In : Biophysical journal. 99, 9, p. L78-L80

Research output: Contribution to journalArticle

Single exposure to radiation produces early anti-angiogenic effects in mouse aorta

Soucy, K. G., Attarzadeh, D. O., Ramachandran, R., Soucy, P. A., Romer, L. H., Shoukas, A. A. & Berkowitz, D. E., Aug 1 2010, In : Radiation and Environmental Biophysics. 49, 3, p. 397-404 8 p.

Research output: Contribution to journalArticle

2009

Cell traction forces direct fibronectin matrix assembly

Lemmon, C. A., Chen, C. S. & Romer, L. H., Jan 21 2009, In : Biophysical journal. 96, 2, p. 729-738 10 p.

Research output: Contribution to journalArticle

Endothelial cell adhesion, signaling, and morphogenesis in fibroblast-derived matrix

Soucy, P. A. & Romer, L. H., Jun 1 2009, In : Matrix Biology. 28, 5, p. 273-283 11 p.

Research output: Contribution to journalArticle

Integrin α2 mediates selective metastasis to the liver

Yoshimura, K., Meckel, K. F., Laird, L. S., Chia, C. Y., Park, J. J., Olino, K. L., Tsunedomi, R., Harada, T., Iizuka, N., Hazama, S., Kato, Y., Keller, J. W., Thompson, J. M., Chang, F., Romer, L. H., Jain, A., Iacobuzio-Donahue, C., Oka, M., Pardoll, D. M. & Schulick, R. D., Oct 13 2009, In : Cancer Research. 69, 18, p. 7320-7328 9 p.

Research output: Contribution to journalArticle

2008

Selective fluorescent labeling of S-nitrosothiols (S-FLOS): A novel method for studying S-nitrosation

Santhanam, L., Gucek, M., Brown, T. R., Mansharamani, M., Ryoo, S., Lemmon, C. A., Romer, L., Shoukas, A. A., Berkowitz, D. E. & Cole, R. N., Nov 1 2008, In : Nitric Oxide - Biology and Chemistry. 19, 3, p. 295-302 8 p.

Research output: Contribution to journalArticle

FAK potentiates Rac1 activation and localization to matrix adhesion sites: A role for βPIX

Chang, F., Lemmon, C. A., Park, D. & Romer, L. H., Jan 1 2007, In : Molecular biology of the cell. 18, 1, p. 253-264 12 p.

Research output: Contribution to journalArticle

High fidelity functional patterns of an extracellular matrix protein by electron beam-based inactivation

Rundqvist, J., Mendoza, B., Werbin, J. L., Heinz, W. F., Lemmon, C., Romer, L. H., Haviland, D. B. & Hoh, J. H., Jan 10 2007, In : Journal of the American Chemical Society. 129, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

Micropatterns of an extracellular matrix protein with defined information content

Werbin, J. L., Heinz, W. F., Romer, L. H. & Hoh, J. H., Oct 23 2007, In : Langmuir. 23, 22, p. 10883-10886 4 p.

Research output: Contribution to journalArticle

Regulation of hyperoxia-induced NADPH oxidase activation in human lung endothelial cells by the actin cytoskeleton and cortactin

Usatyuk, P. V., Romer, L. H., He, D., Parinandi, N. L., Kleinberg, M. E., Zhan, S., Jacobson, J. R., Dudek, S. M., Pendyala, S., Garcia, J. G. N. & Natarajan, V., Aug 10 2007, In : Journal of Biological Chemistry. 282, 32, p. 23284-23295 12 p.

Research output: Contribution to journalArticle

2006

An inhibitory role for FAK in regulating proliferation: A link between limited adhesion and RhoA-ROCK signaling

Pirone, D. M., Liu, W. F., Ruiz, S. A., Gao, L., Raghavan, S., Lemmon, C. A., Romer, L. H. & Chen, C. S., Jul 17 2006, In : Journal of Cell Biology. 174, 2, p. 277-288 12 p.

Research output: Contribution to journalArticle

Focal adhesion kinase is involved in type III group B streptococcal invasion of human brain microvascular endothelial cells

Shin, S., Maneesh, P. S., Lee, J. S., Romer, L. H. & Kim, K. S., Jan 1 2006, In : Microbial Pathogenesis. 41, 4-5, p. 168-173 6 p.

Research output: Contribution to journalArticle

Focal adhesions: Paradigm for a signaling nexus

Romer, L. H., Birukov, K. G. & Garcia, J. G. N., Mar 1 2006, In : Circulation research. 98, 5, p. 606-616 11 p.

Research output: Contribution to journalReview article

Oxidized low-density lipoprotein-dependent endothelial arginase II activation contributes to impaired nitric oxide signaling

Ryoo, S., Lemmon, C. A., Soucy, K. G., Gupta, G., White, A. R., Nyhan, D., Shoukas, A., Romer, L. H. & Berkowitz, D. E., Oct 1 2006, In : Circulation research. 99, 9, p. 951-960 10 p.

Research output: Contribution to journalArticle