Leslie Cope

Associate Professor

School of Medicine

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Neoplasms Medicine & Life Sciences

Genes Medicine & Life Sciences

Breast Neoplasms Medicine & Life Sciences

Genome Medicine & Life Sciences

Mutation Medicine & Life Sciences

Gene Expression Medicine & Life Sciences

DNA Medicine & Life Sciences

Methylation Medicine & Life Sciences

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Research Output 2001 2017

101 Article
2 Comment/debate

Combination epigenetic therapy in advanced breast cancer with 5-azacitidine and entinostat: A phase II national cancer institute/stand up to cancer study

Connolly, R. M. , Li, H. , Jankowitz, R. C. , Zhang, Z. , Rudek, M. A. , Jeter, S. C. , Slater, S. A. , Powers, P. , Wolff, A. C. , Fetting, J. H. , Brufsky, A. , Piekarz, R. , Ahuja, N. , Laird, P. W. , Shen, H. , Weisenberger, D. J. , Cope, L. , Herman, J. G. , Somlo, G. , Garcia, A. A. & 5 others Jones, P. A., Baylin, S. B., Davidson, N. E., Zahnow, C. A. & Stearns, V. Jun 1 2017 In : Clinical Cancer Research. 23, 11, p. 2691-2701 11 p.

Research output: Contribution to journal › Article

Azacitidine

National Cancer Institute (U.S.)

Epigenomics

Breast Neoplasms

Neoplasms

Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma

Fishbein, L. , Leshchiner, I. , Walter, V. , Danilova, L. , Robertson, A. G. , Johnson, A. R. , Lichtenberg, T. M. , Murray, B. A. , Ghayee, H. K. , Else, T. , Ling, S. , Jefferys, S. R. , de Cubas, A. A. , Wenz, B. , Korpershoek, E. , Amelio, A. L. , Makowski, L. , Rathmell, W. K. , Gimenez-Roqueplo, A. P. , Giordano, T. J. & 212 others Asa, S. L., Tischler, A. S., Akbani, R., Ally, A., Amar, L., Amelio, A. L., Arachchi, H., Asa, S. L., Auchus, R. J., Auman, J. T., Baertsch, R., Balasundaram, M., Balu, S., Bartsch, D. K., Baudin, E., Bauer, T., Beaver, A., Benz, C., Beroukhim, R., Beuschlein, F., Bodenheimer, T., Boice, L., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Carter, S., Cassol, C. A., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cope, L., Crain, D., Curley, E., Danilova, L., de Cubas, A. A., de Krijger, R. R., Demchok, J. A., Deutschbein, T., Dhalla, N., Dimmock, D., Dinjens, W. N. M., Else, T., Eng, C., Eschbacher, J., Fassnacht, M., Felau, I., Feldman, M., Ferguson, M. L., Fiddes, I., Fishbein, L., Frazer, S., Gabriel, S. B., Gardner, J., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Geurts, J., Ghayee, H. K., Gimenez-Roqueplo, A. P., Giordano, T. J., Goldman, M., Graim, K., Gupta, M., Haan, D., Hahner, S., Hantel, C., Haussler, D., Hayes, D. N., Heiman, D. I., Hoadley, K. A., Holt, R. A., Hoyle, A. P., Huang, M., Hunt, B., Hutter, C. M., Jefferys, S. R., Johnson, A. R., Jones, S. J. M., Jones, C. D., Kasaian, K., Kebebew, E., Kim, J., Kimes, P., Knijnenburg, T., Korpershoek, E., Lander, E., Lawrence, M. S., Lechan, R., Lee, D., Leraas, K. M., Lerario, A., Leshchiner, I., Lichtenberg, T. M., Lin, P., Ling, S., Liu, J., LiVolsi, V. A., Lolla, L., Lotan, Y., Lu, Y., Ma, Y., Maison, N., Makowski, L., Mallery, D., Mannelli, M., Marquard, J., Marra, M. A., Matthew, T., Mayo, M., Méatchi, T., Meng, S., Merino, M. J., Mete, O., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Morozova, O., Morris, S., Mose, L. E., Mungall, A. J., Murray, B. A., Naresh, R., Nathanson, K. L., Newton, Y., Ng, S., Ni, Y., Noble, M. S., Nwariaku, F., Pacak, K., Parker, J. S., Paul, E., Penny, R., Perou, C. M., Perou, A. H., Pihl, T., Powers, J., Rabaglia, J., Radenbaugh, A., Ramirez, N. C., Rao, A., Rathmell, W. K., Riester, A., Roach, J., Robertson, A. G., Sadeghi, S., Saksena, G., Salama, S., Saller, C., Sandusky, G., Sbiera, S., Schein, J. E., Schumacher, S. E., Shelton, C., Shelton, T., Sheth, M., Shi, Y., Shih, J., Shmulevich, I., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Sokolov, A., Soloway, M. G., Sougnez, C., Stuart, J., Sun, C., Swatloski, T., Tam, A., Tan, D., Tarnuzzer, R., Tarvin, K., Thiessen, N., Thorne, L. B., Timmers, H. J., Tischler, A. S., Tse, K., Uzunangelov, V., van Berkel, A., Veluvolu, U., Vicha, A., Voet, D., Waldmann, J., Walter, V., Wan, Y., Wang, Z., Wang, T. S., Weaver, J., Weinstein, J. N., Weismann, D., Wenz, B., Wilkerson, M. D., Wise, L., Wong, T., Wong, C., Wu, Y., Yang, L., Zelinka, T., Zenklusen, J. C., Zhang, J. . J., Zhang, W., Zhu, J., Zinzindohoué, F., Zmuda, E., Pacak, K., Nathanson, K. L. & Wilkerson, M. D. Feb 13 2017 In : Cancer Cell. 31, 2, p. 181-193 13 p.

Research output: Contribution to journal › Article

Paraganglioma

Pheochromocytoma

Genes

Germ-Line Mutation

Phosphotransferases

Erratum: Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses (Cell (2015) 162(5) (974–986) (S009286741500848X) (10.1016/j.cell.2015.07.011))

Chiappinelli, K. B. , Strissel, P. L. , Desrichard, A. , Li, H. , Henke, C. , Akman, B. , Hein, A. , Rote, N. S. , Cope, L. M. , Snyder, A. , Makarov, V. , Budhu, S. , Slamon, D. J. , Wolchok, J. D. , Pardoll, D. M. , Beckmann, M. W. , Zahnow, C. A. , Merghoub, T. , Chan, T. A. , Baylin, S. B. & 1 others Strick, R. Apr 6 2017 In : Cell. 169, 2, p. 361 1 p.

Research output: Contribution to journal › Comment/debate

Endogenous Retroviruses

DNA Methylation

Interferons

Neoplasms

Caprylates

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

Le, D. T. , Durham, J. N. , Smith, K. N. , Wang, H. , Bartlett, B. R. , Aulakh, L. K. , Lu, S. , Kemberling, H. , Wilt, C. , Luber, B. S. , Wong, F. , Azad, N. S. , Rucki, A. A. , Laheru, D. , Donehower, R. , Zaheer, A. , Fisher, G. A. , Crocenzi, T. S. , Lee, J. J. , Greten, T. F. & 26 others Duffy, A. G., Ciombor, K. K., Eyring, A. D., Lam, B. H., Joe, A., Kang, S. P., Holdhoff, M., Danilova, L., Cope, L., Meyer, C., Zhou, S., Goldberg, R. M., Armstrong, D. K., Bever, K. M., Fader, A. N., Taube, J., Housseau, F., Spetzler, D., Xiao, N., Pardoll, D. M., Papadopoulos, N., Kinzler, K. W., Eshleman, J. R., Vogelstein, B., Anders, R. A. & Diaz, L. A. Jul 28 2017 In : Science. 357, 6349, p. 409-413 5 p.

Research output: Contribution to journal › Article

Neoplasms

Disease-Free Survival

Colorectal Neoplasms

Clone Cells

Genome

Monitoring of serum DNA methylation as an early independent marker of response and survival in metastatic breast cancer: TBCRC 005 prospective biomarker study

Visvanathan, K., Fackler, M. S., Zhang, Z., Lopez-Bujanda, Z. A., Jeter, S. C., Sokoll, L. J., Garrett-Mayer, E., Cope, L. M., Umbricht, C. B., Euhus, D. M., Forero, A., Storniolo, A. M., Nanda, R., Lin, N. U., Carey, L. A., Ingle, J. N., Sukumar, S. & Wolff, A. C. Mar 1 2017 In : Journal of Clinical Oncology. 35, 7, p. 751-758 8 p.

Research output: Contribution to journal › Article

DNA Methylation

Methylation

Biological Markers

Prospective Studies

Breast Neoplasms