Lei Zheng

Associate Professor

19992019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1999 2019

Filter
Article
2019

Anti-pancreatic tumor efficacy of a Listeria-based, Annexin A2-targeting immunotherapy in combination with anti-PD-1 antibodies

Kim, V. M., Blair, A. B., Lauer, P., Foley, K., Che, X., Soares, K., Xia, T., Muth, S. T., Kleponis, J., Armstrong, T. D., Wolfgang, C., Jaffee, E., Brockstedt, D. & Zheng, L., May 22 2019, In : Journal for immunotherapy of cancer. 7, 1, 132.

Research output: Contribution to journalArticle

Open Access
Annexin A2
Annexins
Listeria
Immunotherapy
Adenocarcinoma

Axon Guidance Molecules Promote Perineural Invasion and Metastasis of Orthotopic Pancreatic Tumors in Mice

Jurcak, N. R., Rucki, A. A., Muth, S., Thompson, E., Sharma, R., Ding, D., Zhu, Q., Eshleman, J., Anders, R. A., Jaffee, E., Fujiwara, K. & Zheng, L., Sep 1 2019, In : Gastroenterology. 157, 3, p. 838-850.e6

Research output: Contribution to journalArticle

Adenocarcinoma
Neoplasm Metastasis
Neoplasms
Spinal Ganglia
Annexin A2

Determining the optimal number of examined lymph nodes for accurate staging of pancreatic cancer: An analysis using the nodal staging score model

Hua, J., Zhang, B., Xu, J., Liu, J., Ni, Q., He, J., Zheng, L., Yu, X. & Shi, S., Jan 1 2019, (Accepted/In press) In : European Journal of Surgical Oncology.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Lymph Nodes
Survival
Neoplasms
Odds Ratio

Dissecting the stromal signalingandregulation of myeloid cells and memory effector T cells in pancreatic cancer

Blair, A. B., Kim, V. M., Muth, S. T., Saung, M. T., Lokker, N., Blouw, B., Armstrong, T. D., Jaffee, E. M., Tsujikawa, T., Coussens, L. M., He, J., Burkhart, R. A., Wolfgang, C. L. & Zheng, L., Sep 1 2019, In : Clinical Cancer Research. 25, 17, p. 5351-5363 13 p.

Research output: Contribution to journalArticle

Myeloid Cells
Pancreatic Neoplasms
Adenocarcinoma
T-Lymphocytes
Hyaluronic Acid

E2F1 and E2F7 differentially regulate KPNA2 to promote the development of gallbladder cancer

Xiang, S., Wang, Z., Ye, Y., Zhang, F., Li, H., Yang, Y., Miao, H., Liang, H., Zhang, Y., Jiang, L., Hu, Y., Zheng, L., Liu, X. & Liu, Y., Feb 21 2019, In : Oncogene. 38, 8, p. 1269-1281 13 p.

Research output: Contribution to journalArticle

Gallbladder Neoplasms
E2F7 Transcription Factor
Neoplasms
karyopherin alpha 2
E2F1 Transcription Factor

Histomorphology of pancreatic cancer in patients with inherited ATM serine/threonine kinase pathogenic variants

Hutchings, D., Jiang, Z., Skaro, M., Weiss, M. J., Wolfgang, C., Makary, M. A., He, J., Cameron, J. L., Zheng, L., Klimstra, D. S., Brand, R. E., Singhi, A. D., Goggins, M. S., Klein, A., Roberts, N. & Hruban, R. H., Jan 1 2019, In : Modern Pathology.

Research output: Contribution to journalArticle

Protein-Serine-Threonine Kinases
Pancreatic Neoplasms
Colloids
Adenocarcinoma
Carcinoma

IDO1 inhibition potentiates vaccine-induced immunity against pancreatic adenocarcinoma

Blair, A. B., Kleponis, J., Thomas, D. L., Muth, S. T., Murphy, A., Kim, V. & Zheng, L., Apr 1 2019, In : The Journal of clinical investigation. 129, 4, p. 1742-1755 14 p.

Research output: Contribution to journalArticle

Open Access
Active Immunotherapy
Immunity
Adenocarcinoma
Vaccines
T-Lymphocytes

Immune checkpoint inhibitor-induced inflammatory arthritis persists after immunotherapy cessation

Braaten, T. J., Brahmer, J., Forde, P., Le, D., Lipson, E., Naidoo, J., Schollenberger, M., Zheng, L., Bingham, C., Shah, A. & Cappelli, L., Jan 1 2019, (Accepted/In press) In : Annals of the rheumatic diseases.

Research output: Contribution to journalArticle

Immunotherapy
Arthritis
Tumors
Immunosuppressive Agents
Logistics

Monitoring Tumor Burden in Response to FOLFIRINOX Chemotherapy Via Profiling Circulating Cell-Free DNA in Pancreatic Cancer

Wei, T., Zhang, Q., Li, X., Su, W., Li, G., Ma, T., Gao, S., Lou, J., Que, R., Zheng, L., Bai, X. & Liang, T., Jan 1 2019, In : Molecular Cancer Therapeutics. 18, 1, p. 196-203 8 p.

Research output: Contribution to journalArticle

Tumor Burden
Pancreatic Neoplasms
Drug Therapy
DNA
Adenocarcinoma

Signaling in the microenvironment of pancreatic cancer: Transmitting along the nerve

Jurcak, N. & Zheng, L., Jan 1 2019, In : Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Tumor Microenvironment
Pancreatic Neoplasms
Adenocarcinoma
Disease Progression
Neoplasms

Survival in Locally Advanced Pancreatic Cancer After Neoadjuvant Therapy and Surgical Resection

Gemenetzis, G., Groot, V. P., Blair, A. B., Laheru, D. A., Zheng, L., Narang, A. K., Fishman, E. K., Hruban, R. H., Yu, J., Burkhart, R. A., Cameron, J. L., Weiss, M. J., Wolfgang, C. L. & He, J., Aug 1 2019, In : Annals of surgery. 270, 2, p. 340-347 8 p.

Research output: Contribution to journalArticle

Neoadjuvant Therapy
Pancreatic Neoplasms
Survival
gemcitabine
Neoplasms

The Significance of Ascites in Patients with Pancreatic Ductal Adenocarcinoma: A Case-Control Study

Baretti, M., Pulluri, B., Tsai, H. L., Blackford, A. L., Wolfgang, C., Laheru, D., Zheng, L., Herman, J., Le, D., Narang, A. & De Jesus-Acosta, A., Apr 1 2019, In : Pancreas. 48, 4, p. 585-589 5 p.

Research output: Contribution to journalArticle

Ascites
Case-Control Studies
Adenocarcinoma
Confidence Intervals
Survival

Vimentin-positive circulating tumor cells as a biomarker for diagnosis and treatment monitoring in patients with pancreatic cancer

Wei, T., Zhang, X., Zhang, Q., Yang, J., Chen, Q., Wang, J., Li, X., Chen, J., Ma, T., Li, G., Gao, S., Lou, J., Que, R., Wang, Y., Dang, X., Zheng, L., Liang, T. & Bai, X., Jun 28 2019, In : Cancer Letters. 452, p. 237-243 7 p.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Physiologic Monitoring
Vimentin
Pancreatic Neoplasms
Biomarkers

ZIP4 Promotes Muscle Wasting and Cachexia in Mice With Orthotopic Pancreatic Tumors by Stimulating RAB27B-Regulated Release of Extracellular Vesicles From Cancer Cells

Yang, J., Zhang, Z., Zhang, Y., Ni, X., Zhang, G., Cui, X., Liu, M., Xu, C., Zhang, Q., Zhu, H., Yan, J., Zhu, V. F., Luo, Y., Hagan, J. P., Li, Z., Fang, J., Jatoi, A., Fernandez-Zapico, M. E., Zheng, L., Edil, B. H. & 4 others, Bronze, M. S., Houchen, C. W., Li, Y. P. & Li, M., Feb 1 2019, In : Gastroenterology. 156, 3, p. 722-734.e6

Research output: Contribution to journalArticle

Cachexia
Skeletal Muscle Fibers
Pancreatic Neoplasms
Muscles
p38 Mitogen-Activated Protein Kinases
2018
Immunotherapy
Arthritis
Immunosuppression
Neoplasms
Phenotype

HALO 202: Randomized phase II Study of PEGPH20 Plus Nab-Paclitaxel/Gemcitabine Versus Nab-Paclitaxel/Gemcitabine in Patients With Untreated, Metastatic Pancreatic Ductal Adenocarcinoma

Hingorani, S. R., Zheng, L., Bullock, A. J., Seery, T. E., Harris, W. P., Sigal, D. S., Braiteh, F., Ritch, P. S., Zalupski, M. M., Bahary, N., Oberstein, P. E., Wang-Gillam, A., Wu, W., Chondros, D., Jiang, P., Khelifa, S., Pu, J., Aldrich, C. & Hendifar, A. E., Feb 1 2018, In : Journal of Clinical Oncology. 36, 4, p. 359-366 8 p.

Research output: Contribution to journalArticle

gemcitabine
Hyaluronic Acid
Adenocarcinoma
Paclitaxel
Enoxaparin

Is a Pathological Complete Response Following Neoadjuvant Chemoradiation Associated with Prolonged Survival in Patients with Pancreatic Cancer?

He, J., Blair, A. B., Groot, V. P., Javed, A. A., Burkhart, R., Gemenetzis, G., Hruban, R. H., Waters, K. M., Poling, J., Zheng, L., Laheru, D., Herman, J. M., Makary, M. A., Weiss, M. J., Cameron, J. L. & Wolfgang, C., Jul 1 2018, In : Annals of Surgery. 268, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Survival
Adenocarcinoma
Disease-Free Survival
Lymph Nodes

Outcome of Patients with Borderline Resectable Pancreatic Cancer in the Contemporary Era of Neoadjuvant Chemotherapy

Javed, A. A., Wright, M. J., Siddique, A., Blair, A. B., Ding, D., Burkhart, R., Makary, M. A., Cameron, J. L., Narang, A., Herman, J., Zheng, L., Laheru, D., Weiss, M. J., Wolfgang, C. & He, J., Jan 1 2018, (Accepted/In press) In : Journal of Gastrointestinal Surgery.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Drug Therapy
Disease Progression
Comorbidity
Pancreas
Pancreatic Neoplasms
Radiotherapy
Radiation
Drug Therapy
Adenocarcinoma

Stereotactic body radiation therapy for palliative management of pancreatic adenocarcinoma in elderly and medically inoperable patients

Ryan, J. F., Rosati, L. M., Groot, V. P., Le, D., Zheng, L., Laheru, D., Shin, E., Jackson, J., Moore, J., Narang, A. & Herman, J. M., Jan 1 2018, In : Oncotarget. 9, 23, p. 16427-16436 10 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Radiotherapy
Disease-Free Survival
Induction Chemotherapy
Survival

Targeting myeloid-inflamed tumor with anti-CSF-1R antibody expands CD137+ effector T-cells in the murine model of pancreatic cancer

Saung, M. T., Muth, S., Ding, D., Thomas, D. L., Blair, A. B., Tsujikawa, T., Coussens, L., Jaffee, E. M. & Zheng, L., Nov 13 2018, In : Journal for ImmunoTherapy of Cancer. 6, 1, 1 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
T-Lymphocytes
Antibodies
Adenocarcinoma
Neoplasms

The interface of pancreatic cancer with diabetes, obesity, and inflammation: Research gaps and opportunities: Summary of a national Institute of Diabetes and digestive and kidney diseases workshop

Abbruzzese, J. L., Andersen, D. K., Borrebaeck, C. A. K., Chari, S. T., Costello, E., Cruz-Monserrate, Z., Eibl, G., Engleman, E. G., Fisher, W. E., Habtezion, A., Kim, S. K., Korc, M., Logsdon, C., Lyssiotis, C. A., Pandol, S. J., Rustgi, A., Wolfe, B. M., Zheng, L. & Powers, A. C., May 1 2018, In : Pancreas. 47, 5, p. 516-525 10 p.

Research output: Contribution to journalArticle

National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Pancreatic Neoplasms
Adenocarcinoma
Obesity
Inflammation

ZIP4 promotes pancreatic cancer progression by repressing ZO-1 and claudin-1 through a ZEB1-dependent transcriptional mechanism

Liu, M., Yang, J., Zhang, Y., Zhou, Z., Cui, X., Zhang, L., Fung, K. M., Zheng, W., Allard, F. D., Yee, E. U., Ding, K., Wu, H., Liang, Z., Zheng, L., Fernandez-Zapico, M. E., Li, Y. P., Bronze, M. S., Morris, K. T., Postier, R. G., Houchen, C. W. & 2 others, Yang, J. & Li, M., Jul 1 2018, In : Clinical Cancer Research. 24, 13, p. 3186-3196 11 p.

Research output: Contribution to journalArticle

Claudin-1
Pancreatic Neoplasms
Paxillin
Heterografts
Neoplasms
2017

Current Standards of Chemotherapy for Pancreatic Cancer

Saung, M. T. & Zheng, L., 2017, (Accepted/In press) In : Clinical Therapeutics.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Combination Drug Therapy
Drug Therapy
gemcitabine
Phase III Clinical Trials

Dual inhibition of Hedgehog and c-Met pathways for pancreatic cancer treatment

Rucki, A. A., Xiao, Q., Muth, S., Chen, J., Che, X., Kleponis, J., Sharma, R., Anders, R. A., Jaffee, E. & Zheng, L., Nov 1 2017, In : Molecular Cancer Therapeutics. 16, 11, p. 2399-2409 11 p.

Research output: Contribution to journalArticle

Hedgehogs
Pancreatic Neoplasms
Adenocarcinoma
gemcitabine
Tumor Burden

Hedgehog signaling stimulates Tenascin C to promote invasion of pancreatic ductal adenocarcinoma cells through Annexin A2

Foley, K., Muth, S., Jaffee, E. & Zheng, L., Feb 4 2017, (Accepted/In press) In : Cell Adhesion and Migration. p. 1-10 10 p.

Research output: Contribution to journalArticle

Annexins
Tenascin
Adenocarcinoma
Stromal Cells
Neoplasms

Hepatitis B virus infection and exposure among foreign-born asian americans in the U.S.

Juon, H. S., Kim, F., Strong, C., Park, E., Zheng, L., Li, Z. & Lee, S., Jan 1 2017, In : Hepatitis Monthly. 17, 1, p. 1-6 6 p., e43018.

Research output: Contribution to journalArticle

Asian Americans
Virus Diseases
Hepatitis B virus
Hepatitis B Surface Antigens
Hepatitis B

Heterogeneous stromal signaling within the tumor microenvironment controls the metastasis of pancreatic cancer

Rucki, A. A., Foley, K., Zhang, P., Xiao, Q., Kleponis, J., Wu, A. A., Sharma, R., Mo, G., Liu, A., Van Eyk, J., Jaffee, E. & Zheng, L., Jan 1 2017, In : Cancer Research. 77, 1, p. 41-52 12 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Pancreatic Neoplasms
Adenocarcinoma
Neoplasm Metastasis
Insulin-Like Growth Factor I

LncRNA-PAGBC acts as a microRNA sponge and promotes gallbladder tumorigenesis

Wu, X. S., Wang, F., Li, H. F., Hu, Y. P., Jiang, L., Zhang, F., Li, M. L., Wang, X. A., Jin, Y. P., Zhang, Y. J., Lu, W., Wu, W. G., Shu, Y. J., Weng, H., Cao, Y., Bao, R. F., Liang, H. B., Wang, Z., Zhang, Y. C., Gong, W. & 3 others, Zheng, L., Sun, S. H. & Liu, Y. B., Oct 1 2017, In : EMBO Reports. 18, 10, p. 1837-1853 17 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Porifera
Gallbladder
MicroRNAs
Gallbladder Neoplasms

Long-term survival benefit of upfront chemotherapy in patients with newly diagnosed borderline resectable pancreatic cancer

Shrestha, B., Sun, Y., Faisal, F., Kim, V., Soares, K., Blair, A., Herman, J. M., Narang, A., Dholakia, A. S., Rosati, L., Hacker-Prietz, A., Chen, L., Laheru, D., De Jesus-Acosta, A., Le, D., Donehower, R. C., Azad, N., Diaz, L. A., Murphy, A., Lee, V. & 11 others, Fishman, E. K., Hruban, R. H., Liang, T., Cameron, J. L., Makary, M. A., Weiss, M. J., Ahuja, N., He, J., Wolfgang, C., Huang, C. Y. & Zheng, L., Jul 1 2017, In : Cancer Medicine. 6, 7, p. 1552-1562 11 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Drug Therapy
Neoadjuvant Therapy
Survival
Adenocarcinoma

Microfluidic device for primary tumor spheroid isolation

Zhou, J., Su, J., Fu, X., Zheng, L. & Yin, Z., Aug 7 2017, In : Experimental Hematology and Oncology. 6, 1, 22.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Cell Culture Techniques
Neoplasms
Cellular Spheroids
Drug Discovery

Modified-FOLFIRINOX in metastatic pancreatic cancer: A prospective study in Chinese population

Li, X., Ma, T., Zhang, Q., Chen, Y. G., Guo, C. X., Shen, Y. N., Sun, P. W., Li, G. G., Gao, S. L., Que, R. S., Lou, J. Y., Yu, R. S., Yuan, Y., Wei, Q. C., Wei, S. M., Zhang, Y., Zheng, L., Bai, X. L. & Liang, T. B., Oct 10 2017, In : Cancer Letters. 406, p. 22-26 5 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Prospective Studies
oxaliplatin
irinotecan
Population

Modified staging classification for pancreatic neuroendocrine tumors on the basis of the American Joint Committee on Cancer and European Neuroendocrine Tumor Society Systems

Luo, G., Javed, A., Strosberg, J. R., Jin, K., Zhang, Y., Liu, C., Xu, J., Soares, K., Weiss, M. J., Zheng, L., Wolfgang, C., Cives, M., Wong, J., Wang, W., Sun, J., Shao, C., Tan, H., Li, J., Ni, Q., Shen, L. & 4 others, Chen, M., He, J., Chen, J. & Yu, X., Jan 20 2017, In : Journal of Clinical Oncology. 35, 3, p. 274-280 7 p.

Research output: Contribution to journalArticle

Neuroendocrine Tumors
Neoplasm Staging
Neoplasms
Registries

Multiplex Proximity Ligation Assay to Identify Potential Prognostic Biomarkers for Improved Survival in Locally Advanced Pancreatic Cancer Patients Treated With Stereotactic Body Radiation Therapy

Rao, A. D., Liu, Y., von Eyben, R., Hsu, C. C., Hu, C., Rosati, L. M., Parekh, A., Ng, K., Hacker-Prietz, A., Zheng, L., Pawlik, T. M., Laheru, D., Jaffee, E., Weiss, M. J., Le, D., Hruban, R. H., De Jesus-Acosta, A., Wolfgang, C., Narang, A., Chang, D. T. & 2 others, Koong, A. C. & Herman, J. M., Jan 1 2017, (Accepted/In press) In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journalArticle

biomarkers
Pancreatic Neoplasms
Ligation
proximity
radiation therapy

MYBL2 is a Potential Prognostic Marker that Promotes Cell Proliferation in Gallbladder Cancer

Liang, H. B., Cao, Y., Ma, Q., Shu, Y. J., Wang, Z., Zhang, F., Ye, Y. Y., Li, H. F., Xiang, S. S., Song, X. L., Xu, Y., Zhang, Y. C., Bao, R. F., Yuan, R. Y., Zhang, Y. J., Hu, Y. P., Jiang, L., Li, M. L., Wang, X. A., Wu, X. S. & 9 others, Wu, W. G., Zhao, S., Fand, Y., Cui, X. P., Lu, Y. S., Zhou, J., Zheng, L., Gong, W. & Liu, Y. B., Apr 17 2017, (Accepted/In press) In : Cellular Physiology and Biochemistry. p. 2117-2131 15 p.

Research output: Contribution to journalArticle

Gallbladder Neoplasms
Cell Proliferation
Nude Mice
Neoplasms
Cholecystitis

Olaparib in combination with irinotecan, cisplatin, and mitomycin c in patients with advanced pancreatic cancer

Yarchoan, M., Myzak, M. C., Johnson, B. A., De Jesus-Acosta, A., Le, D., Jaffee, E., Azad, N., Donehower, R. C., Zheng, L., Oberstein, P. E., Fine, R. L., Laheru, D. & Goggins, M. S., 2017, In : Oncotarget. 8, 27, p. 44073-44081 9 p.

Research output: Contribution to journalArticle

irinotecan
Mitomycin
Pancreatic Neoplasms
Cisplatin
Adenocarcinoma

Patterns, Timing, and Predictors of Recurrence Following Pancreatectomy for Pancreatic Ductal Adenocarcinoma

Groot, V. P., Rezaee, N., Wu, W., Cameron, J. L., Fishman, E. K., Hruban, R. H., Weiss, M. J., Zheng, L., Wolfgang, C. & He, J., Mar 23 2017, (Accepted/In press) In : Annals of Surgery.

Research output: Contribution to journalArticle

Pancreatectomy
Adenocarcinoma
Recurrence
Adjuvant Chemoradiotherapy
Adjuvant Chemotherapy

Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis

Tsujikawa, T., Kumar, S., Borkar, R. N., Azimi, V., Thibault, G., Chang, Y. H., Balter, A., Kawashima, R., Choe, G., Sauer, D., El Rassi, E., Clayburgh, D. R., Kulesz-Martin, M. F., Lutz, E. R., Zheng, L., Jaffee, E., Leyshock, P., Margolin, A. A., Mori, M., Gray, J. W. & 2 others, Flint, P. W. & Coussens, L. M., Apr 4 2017, In : Cell Reports. 19, 1, p. 203-217 15 p.

Research output: Contribution to journalArticle

Tumors
Immunohistochemistry
Tissue
Biomarkers
Papillomaviridae

Stereotactic Body Radiation Therapy for Isolated Local Recurrence After Surgical Resection of Pancreatic Ductal Adenocarcinoma Appears to be Safe and Effective

Ryan, J. F., Groot, V. P., Rosati, L. M., Hacker-Prietz, A., Narang, A., McNutt, T., Jackson, J. F., Le, D., Jaffee, E., Zheng, L., Laheru, D., He, J., Pawlik, T. M., Weiss, M. J., Wolfgang, C. & Herman, J. M., Oct 23 2017, (Accepted/In press) In : Annals of Surgical Oncology. p. 1-10 10 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Radiotherapy
Recurrence
Maintenance Chemotherapy
Disease-Free Survival

Stromal Annexin A2 expression is predictive of decreased survival in pancreatic cancer

Murphy, A., Foley, K., Rucki, A. A., Xia, T., Jaffee, E., Huang, C. Y. & Zheng, L., Jan 1 2017, In : Oncotarget. 8, 63, p. 106405-106414 10 p.

Research output: Contribution to journalArticle

Annexin A2
Annexins
Pancreatic Neoplasms
Adenocarcinoma
Survival
2016

Blocking NF-κ B is essential for the immunotherapeutic effect of recombinant IL18 in pancreatic cancer

Guo, X., Zheng, L., Jiang, J., Zhao, Y., Wang, X., Shen, M., Zhu, F., Tian, R., Shi, C., Xu, M., Li, X., Peng, F., Zhang, H., Feng, Y., Xie, Y., Xu, X., Jia, W., He, R., Xie, C., Hu, J. & 3 others, Ye, D., Wang, M. & Qin, R., Dec 1 2016, In : Clinical Cancer Research. 22, 23, p. 5939-5950 12 p.

Research output: Contribution to journalArticle

Interleukin-18
Pancreatic Neoplasms
Survival
Therapeutic Uses
Neoplasms

Cancer-associated fibroblasts in pancreatic cancer are reprogrammed by tumor-induced alterations in genomic DNA methylation

Xiao, Q., Zhou, D., Rucki, A. A., Williams, J., Zhou, J., Mo, G., Murphy, A., Fujiwara, K., Kleponis, J., Salman, B., Wolfgang, C., Anders, R. A., Zheng, S., Jaffee, E. & Zheng, L., Sep 15 2016, In : Cancer Research. 76, 18, p. 5395-5404 10 p.

Research output: Contribution to journalArticle

DNA Methylation
Pancreatic Neoplasms
Adenocarcinoma
Methylation
Neoplasms

Circulating Tumor Cell Phenotype Predicts Recurrence and Survival in Pancreatic Adenocarcinoma

Poruk, K. E., Valero, V., Saunders, T., Blackford, A. L., Griffin, J. F., Poling, J., Hruban, R. H., Anders, R. A., Herman, J., Zheng, L., Rasheed, Z. A., Laheru, D., Ahuja, N., Weiss, M. J., Cameron, J. L., Goggins, M. S., Iacobuzio-Donahue, C. A., Wood, L. D. & Wolfgang, C., Jan 7 2016, (Accepted/In press) In : Annals of Surgery.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Adenocarcinoma
Phenotype
Recurrence
Survival

Genomic change in hepatitis B virus associated with development of hepatocellular carcinoma

Lee, D., Lyu, H., Chung, Y. H., Kim, J. A., Mathews, P., Jaffee, E., Zheng, L., Yu, E., Lee, Y. J. & Ryu, S. H., Jun 21 2016, In : World Journal of Gastroenterology. 22, 23, p. 5393-5399 7 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepatocellular Carcinoma
Mutation
Genotype
Chronic Hepatitis B

Identification of serologic biomarkers for predicting microvascular invasion in hepatocellular carcinoma

Yu, Y. Q., Wang, L., Jin, Y., Zhou, J. L., Geng, Y. H., Jin, X., Zhang, X. X., Yang, J. J., Qian, C. M., Zhou, D. E., Liu, D. R., Peng, S. Y., Luo, Y., Zheng, L. & Li, J. T., Mar 29 2016, In : Oncotarget. 7, 13, p. 16362-16371 10 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Biomarkers
Antibodies
Antigens
Glutathione Synthase

Longer course of induction chemotherapy followed by chemoradiation favors better survival outcomes for patients with locally advanced pancreatic cancer

Faisal, F., Tsai, H. L., Blackford, A., Olino, K., Xia, C., De Jesus-Acosta, A., Le, D., Cosgrove, D., Azad, N., Rasheed, Z., Diaz, L. A., Donehower, R. C., Laheru, D., Hruban, R. H., Fishman, E. K., Edil, B. H., Schulick, R., Wolfgang, C., Herman, J. & Zheng, L., 2016, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 39, 1, p. 18-26 9 p.

Research output: Contribution to journalArticle

Induction Chemotherapy
Pancreatic Neoplasms
Survival
Incidence
Drug Therapy

Neutrophil-to-lymphocyte Ratio is a Predictive Marker for Invasive Malignancy in Intraductal Papillary Mucinous Neoplasms of the Pancreas

Gemenetzis, G., Bagante, F., Griffin, J. F., Rezaee, N., Javed, A. A., Manos, L. L., O'Broin-Lennon, A. M., Wood, L. D., Hruban, R. H., Zheng, L., Zaheer, A., Fishman, E. K., Ahuja, N., Cameron, J. L., Weiss, M. J., He, J. & Wolfgang, C., Sep 14 2016, (Accepted/In press) In : Annals of Surgery.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Neutrophils
Lymphocytes
Neoplasms
Carcinoma

Pancreatic cancer adjuvant radiotherapy target volume design: based on the postoperative local recurrence spatial location

Yu, W., Hu, W., Shui, Y., Zhu, X., Li, C., Ren, X., Bai, X., Yu, R., Shen, L., Liang, T., Zheng, L. & Wei, Q., Oct 19 2016, In : Radiation oncology (London, England). 11, 1, p. 138 1 p.

Research output: Contribution to journalArticle

Adjuvant Radiotherapy
Pancreatic Neoplasms
Recurrence
Superior Mesenteric Artery
Abdomen

Patient-reported outcomes of a multicenter phase 2 study investigating gemcitabine and stereotactic body radiation therapy in locally advanced pancreatic cancer

Rao, A. D., Sugar, E., Chang, D. T., Goodman, K. A., Hacker-Prietz, A., Rosati, L. M., Columbo, L., O'Reilly, E., Fisher, G. A., Zheng, L., Pai, J. S., Griffith, M. E., Laheru, D., Iacobuzio-Donahue, C. A., Wolfgang, C., Koong, A. & Herman, J. M., Nov 1 2016, In : Practical Radiation Oncology. 6, 6, p. 417-424 8 p.

Research output: Contribution to journalArticle

gemcitabine
Pancreatic Neoplasms
Radiotherapy
Quality of Life
Body Image

Targeted DNA Sequencing Reveals Patterns of Local Progression in the Pancreatic Remnant Following Resection of Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas

Pea, A., Yu, J., Rezaee, N., Luchini, C., He, J., Dal Molin, M., Griffin, J. F., Fedor, H., Fesharakizadeh, S., Salvia, R., Weiss, M. J., Bassi, C., Cameron, J. L., Zheng, L., Scarpa, A., Hruban, R. H., O'Broin-Lennon, A. M., Goggins, M. S., Wolfgang, C. & Wood, L. D., Jul 18 2016, (Accepted/In press) In : Annals of Surgery.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
DNA Sequence Analysis
Neoplasms
Pancreas
Second Primary Neoplasms