Lei Zheng

Associate Professor

19992019
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Research Output 1999 2019

2019

A direct podocalyxin–dynamin-2 interaction regulates cytoskeletal dynamics to promote migration and metastasis in pancreatic cancer cells

Wong, B. S., Shea, D. J., Mistriotis, P., Tuntithavornwat, S., Law, R. A., Bieber, J. M., Zheng, L. & Konstantopoulos, K., Jun 1 2019, In : Cancer Research. 79, 11, p. 2878-2891 14 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Neoplasm Metastasis
Dynamin II
Microtubules
Focal Adhesions

Anti-pancreatic tumor efficacy of a Listeria-based, Annexin A2-targeting immunotherapy in combination with anti-PD-1 antibodies

Kim, V. M., Blair, A. B., Lauer, P., Foley, K., Che, X., Soares, K., Xia, T., Muth, S. T., Kleponis, J., Armstrong, T. D., Wolfgang, C., Jaffee, E., Brockstedt, D. & Zheng, L., May 22 2019, In : Journal for immunotherapy of cancer. 7, 1, 132.

Research output: Contribution to journalArticle

Open Access
Annexin A2
Annexins
Listeria
Immunotherapy
Adenocarcinoma

Axon Guidance Molecules Promote Perineural Invasion and Metastasis of Orthotopic Pancreatic Tumors in Mice

Jurcak, N. R., Rucki, A. A., Muth, S., Thompson, E., Sharma, R., Ding, D., Zhu, Q., Eshleman, J., Anders, R. A., Jaffee, E., Fujiwara, K. & Zheng, L., Sep 1 2019, In : Gastroenterology. 157, 3, p. 838-850.e6

Research output: Contribution to journalArticle

Adenocarcinoma
Neoplasm Metastasis
Neoplasms
Spinal Ganglia
Annexin A2

Circulating tumor DNA as a clinical test in resected pancreatic cancer

Groot, V. P., Mosier, S., Javed, A. A., Teinor, J. A., Gemenetzis, G., Ding, D., Haley, L. M., Yu, J., Burkhart, R. A., Hasanain, A., Debeljak, M., Kamiyama, H., Narang, A., Laheru, D. A., Zheng, L., Lin, M. T., Gocke, C. D., Fishman, E. K., Hruban, R. H., Goggins, M. G. & 7 others, Quintus Molenaar, I., Cameron, J. L., Weiss, M. J., Velculescu, V. E., He, J., Wolfgang, C. L. & Eshleman, J. R., Aug 15 2019, In : Clinical Cancer Research. 25, 16, p. 4973-4984 12 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
DNA
Neoplasms
Adenocarcinoma
Recurrence

Determining the optimal number of examined lymph nodes for accurate staging of pancreatic cancer: An analysis using the nodal staging score model

Hua, J., Zhang, B., Xu, J., Liu, J., Ni, Q., He, J., Zheng, L., Yu, X. & Shi, S., Jan 1 2019, (Accepted/In press) In : European Journal of Surgical Oncology.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Lymph Nodes
Survival
Neoplasms
Odds Ratio

Dissecting the stromal signalingandregulation of myeloid cells and memory effector T cells in pancreatic cancer

Blair, A. B., Kim, V. M., Muth, S. T., Saung, M. T., Lokker, N., Blouw, B., Armstrong, T. D., Jaffee, E. M., Tsujikawa, T., Coussens, L. M., He, J., Burkhart, R. A., Wolfgang, C. L. & Zheng, L., Sep 1 2019, In : Clinical Cancer Research. 25, 17, p. 5351-5363 13 p.

Research output: Contribution to journalArticle

Myeloid Cells
Pancreatic Neoplasms
Adenocarcinoma
T-Lymphocytes
Hyaluronic Acid

E2F1 and E2F7 differentially regulate KPNA2 to promote the development of gallbladder cancer

Xiang, S., Wang, Z., Ye, Y., Zhang, F., Li, H., Yang, Y., Miao, H., Liang, H., Zhang, Y., Jiang, L., Hu, Y., Zheng, L., Liu, X. & Liu, Y., Feb 21 2019, In : Oncogene. 38, 8, p. 1269-1281 13 p.

Research output: Contribution to journalArticle

Gallbladder Neoplasms
E2F7 Transcription Factor
Neoplasms
karyopherin alpha 2
E2F1 Transcription Factor

Experts’ consensus on intraoperative radiotherapy for pancreatic cancer

Li, Y., Feng, Q., Jin, J., Shi, S., Zhang, Z., Che, X., Zhang, J., Chen, Y., Wu, X., Chen, R., Li, S., Wang, J., Li, G., Li, F., Dai, M., Zheng, L. & Wang, C., May 1 2019, In : Cancer Letters. 449, p. 1-7 7 p.

Research output: Contribution to journalShort survey

Open Access
Pancreatic Neoplasms
Radiotherapy
Digestive System Neoplasms
Quality Control
China
Dextran
Dextrans
Pancreatic Neoplasms
Fibronectins
Magnetic Resonance Imaging

From immune checkpoints to vaccines: The past, present and future of cancer immunotherapy

Osipov, A., Murphy, A. & Zheng, L., Jan 1 2019, Advances in Cancer Research. Academic Press Inc., (Advances in Cancer Research).

Research output: Chapter in Book/Report/Conference proceedingChapter

Immunotherapy
Vaccines
Neoplasms
Immune System
Oncolytic Viruses

Histomorphology of pancreatic cancer in patients with inherited ATM serine/threonine kinase pathogenic variants

Hutchings, D., Jiang, Z., Skaro, M., Weiss, M. J., Wolfgang, C., Makary, M. A., He, J., Cameron, J. L., Zheng, L., Klimstra, D. S., Brand, R. E., Singhi, A. D., Goggins, M. S., Klein, A., Roberts, N. & Hruban, R. H., Jan 1 2019, In : Modern Pathology.

Research output: Contribution to journalArticle

Protein-Serine-Threonine Kinases
Pancreatic Neoplasms
Colloids
Adenocarcinoma
Carcinoma

IDO1 inhibition potentiates vaccine-induced immunity against pancreatic adenocarcinoma

Blair, A. B., Kleponis, J., Thomas, D. L., Muth, S. T., Murphy, A., Kim, V. & Zheng, L., Apr 1 2019, In : The Journal of clinical investigation. 129, 4, p. 1742-1755 14 p.

Research output: Contribution to journalArticle

Open Access
Active Immunotherapy
Immunity
Adenocarcinoma
Vaccines
T-Lymphocytes

Immune checkpoint inhibitor-induced inflammatory arthritis persists after immunotherapy cessation

Braaten, T. J., Brahmer, J., Forde, P., Le, D., Lipson, E., Naidoo, J., Schollenberger, M., Zheng, L., Bingham, C., Shah, A. & Cappelli, L., Jan 1 2019, (Accepted/In press) In : Annals of the rheumatic diseases.

Research output: Contribution to journalArticle

Immunotherapy
Arthritis
Tumors
Immunosuppressive Agents
Logistics

Monitoring Tumor Burden in Response to FOLFIRINOX Chemotherapy Via Profiling Circulating Cell-Free DNA in Pancreatic Cancer

Wei, T., Zhang, Q., Li, X., Su, W., Li, G., Ma, T., Gao, S., Lou, J., Que, R., Zheng, L., Bai, X. & Liang, T., Jan 1 2019, In : Molecular Cancer Therapeutics. 18, 1, p. 196-203 8 p.

Research output: Contribution to journalArticle

Tumor Burden
Pancreatic Neoplasms
Drug Therapy
DNA
Adenocarcinoma

Precision medicine in pancreatic cancer: treating every patient as an exception

Herbst, B. & Zheng, L., Oct 1 2019, In : The Lancet Gastroenterology and Hepatology. 4, 10, p. 805-810 6 p.

Research output: Contribution to journalComment/debate

Precision Medicine
Pancreatic Neoplasms
Adenocarcinoma
Neoplasms
Disease Management

Signaling in the microenvironment of pancreatic cancer: Transmitting along the nerve

Jurcak, N. & Zheng, L., Jan 1 2019, In : Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Tumor Microenvironment
Pancreatic Neoplasms
Adenocarcinoma
Disease Progression
Neoplasms

Small molecule immunomodulation: The tumor microenvironment and overcoming immune escape

Osipov, A., Saung, M. T., Zheng, L. & Murphy, A. G., Aug 22 2019, In : Journal for immunotherapy of cancer. 7, 1, 224.

Research output: Contribution to journalReview article

Open Access
Tumor Microenvironment
Immunomodulation
Immunotherapy
Focal Adhesion Protein-Tyrosine Kinases
Neoplasms

Survival in Locally Advanced Pancreatic Cancer After Neoadjuvant Therapy and Surgical Resection

Gemenetzis, G., Groot, V. P., Blair, A. B., Laheru, D. A., Zheng, L., Narang, A. K., Fishman, E. K., Hruban, R. H., Yu, J., Burkhart, R. A., Cameron, J. L., Weiss, M. J., Wolfgang, C. L. & He, J., Aug 1 2019, In : Annals of surgery. 270, 2, p. 340-347 8 p.

Research output: Contribution to journalArticle

Neoadjuvant Therapy
Pancreatic Neoplasms
Survival
gemcitabine
Neoplasms

The Significance of Ascites in Patients with Pancreatic Ductal Adenocarcinoma: A Case-Control Study

Baretti, M., Pulluri, B., Tsai, H. L., Blackford, A. L., Wolfgang, C., Laheru, D., Zheng, L., Herman, J., Le, D., Narang, A. & De Jesus-Acosta, A., Apr 1 2019, In : Pancreas. 48, 4, p. 585-589 5 p.

Research output: Contribution to journalArticle

Ascites
Case-Control Studies
Adenocarcinoma
Confidence Intervals
Survival

Vimentin-positive circulating tumor cells as a biomarker for diagnosis and treatment monitoring in patients with pancreatic cancer

Wei, T., Zhang, X., Zhang, Q., Yang, J., Chen, Q., Wang, J., Li, X., Chen, J., Ma, T., Li, G., Gao, S., Lou, J., Que, R., Wang, Y., Dang, X., Zheng, L., Liang, T. & Bai, X., Jun 28 2019, In : Cancer Letters. 452, p. 237-243 7 p.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Physiologic Monitoring
Vimentin
Pancreatic Neoplasms
Biomarkers

ZIP4 Promotes Muscle Wasting and Cachexia in Mice With Orthotopic Pancreatic Tumors by Stimulating RAB27B-Regulated Release of Extracellular Vesicles From Cancer Cells

Yang, J., Zhang, Z., Zhang, Y., Ni, X., Zhang, G., Cui, X., Liu, M., Xu, C., Zhang, Q., Zhu, H., Yan, J., Zhu, V. F., Luo, Y., Hagan, J. P., Li, Z., Fang, J., Jatoi, A., Fernandez-Zapico, M. E., Zheng, L., Edil, B. H. & 4 others, Bronze, M. S., Houchen, C. W., Li, Y. P. & Li, M., Feb 1 2019, In : Gastroenterology. 156, 3, p. 722-734.e6

Research output: Contribution to journalArticle

Cachexia
Skeletal Muscle Fibers
Pancreatic Neoplasms
Muscles
p38 Mitogen-Activated Protein Kinases
2018
Immunotherapy
Arthritis
Immunosuppression
Neoplasms
Phenotype

HALO 202: Randomized phase II Study of PEGPH20 Plus Nab-Paclitaxel/Gemcitabine Versus Nab-Paclitaxel/Gemcitabine in Patients With Untreated, Metastatic Pancreatic Ductal Adenocarcinoma

Hingorani, S. R., Zheng, L., Bullock, A. J., Seery, T. E., Harris, W. P., Sigal, D. S., Braiteh, F., Ritch, P. S., Zalupski, M. M., Bahary, N., Oberstein, P. E., Wang-Gillam, A., Wu, W., Chondros, D., Jiang, P., Khelifa, S., Pu, J., Aldrich, C. & Hendifar, A. E., Feb 1 2018, In : Journal of Clinical Oncology. 36, 4, p. 359-366 8 p.

Research output: Contribution to journalArticle

gemcitabine
Hyaluronic Acid
Adenocarcinoma
Paclitaxel
Enoxaparin

Is a Pathological Complete Response Following Neoadjuvant Chemoradiation Associated with Prolonged Survival in Patients with Pancreatic Cancer?

He, J., Blair, A. B., Groot, V. P., Javed, A. A., Burkhart, R., Gemenetzis, G., Hruban, R. H., Waters, K. M., Poling, J., Zheng, L., Laheru, D., Herman, J. M., Makary, M. A., Weiss, M. J., Cameron, J. L. & Wolfgang, C., Jul 1 2018, In : Annals of Surgery. 268, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Survival
Adenocarcinoma
Disease-Free Survival
Lymph Nodes

New development of biomarkers for gastrointestinal cancers: From neoplastic cells to tumor microenvironment

Zhang, J., Quadri, S., Wolfgang, C. & Zheng, L., Aug 1 2018, In : Biomedicines. 6, 3, 87.

Research output: Contribution to journalReview article

Gastrointestinal Neoplasms
Tumor Microenvironment
Biomarkers
Tumors
Neoplasms

Outcome of Patients with Borderline Resectable Pancreatic Cancer in the Contemporary Era of Neoadjuvant Chemotherapy

Javed, A. A., Wright, M. J., Siddique, A., Blair, A. B., Ding, D., Burkhart, R., Makary, M. A., Cameron, J. L., Narang, A., Herman, J., Zheng, L., Laheru, D., Weiss, M. J., Wolfgang, C. & He, J., Jan 1 2018, (Accepted/In press) In : Journal of Gastrointestinal Surgery.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Drug Therapy
Disease Progression
Comorbidity
Pancreas
Pancreatic Neoplasms
Radiotherapy
Radiation
Drug Therapy
Adenocarcinoma

Precision immuno-oncology: Prospects of individualized immunotherapy for pancreatic cancer

Zhang, J., Wolfgang, C. & Zheng, L., Feb 1 2018, In : Cancers. 10, 2, 39.

Research output: Contribution to journalReview article

Pancreatic Neoplasms
Immunotherapy
Tumor Microenvironment
Neoplasms
Biomarkers

Recent development and clinical application of cancer vaccine: Targeting neoantigens

Pan, R. Y., Chung, W. H., Chu, M. T., Chen, S. J., Chen, H. C., Zheng, L. & Hung, S. I., Jan 1 2018, In : Journal of immunology research. 2018, 4325874.

Research output: Contribution to journalReview article

Open Access
Cancer Vaccines
Immunotherapy
Neoplasm Antigens
Neoplasms
Antigens

Stereotactic body radiation therapy for palliative management of pancreatic adenocarcinoma in elderly and medically inoperable patients

Ryan, J. F., Rosati, L. M., Groot, V. P., Le, D., Zheng, L., Laheru, D., Shin, E., Jackson, J., Moore, J., Narang, A. & Herman, J. M., Jan 1 2018, In : Oncotarget. 9, 23, p. 16427-16436 10 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Radiotherapy
Disease-Free Survival
Induction Chemotherapy
Survival

Targeting myeloid-inflamed tumor with anti-CSF-1R antibody expands CD137+ effector T-cells in the murine model of pancreatic cancer

Saung, M. T., Muth, S., Ding, D., Thomas, D. L., Blair, A. B., Tsujikawa, T., Coussens, L., Jaffee, E. M. & Zheng, L., Nov 13 2018, In : Journal for ImmunoTherapy of Cancer. 6, 1, 1 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
T-Lymphocytes
Antibodies
Adenocarcinoma
Neoplasms

The interface of pancreatic cancer with diabetes, obesity, and inflammation: Research gaps and opportunities: Summary of a national Institute of Diabetes and digestive and kidney diseases workshop

Abbruzzese, J. L., Andersen, D. K., Borrebaeck, C. A. K., Chari, S. T., Costello, E., Cruz-Monserrate, Z., Eibl, G., Engleman, E. G., Fisher, W. E., Habtezion, A., Kim, S. K., Korc, M., Logsdon, C., Lyssiotis, C. A., Pandol, S. J., Rustgi, A., Wolfe, B. M., Zheng, L. & Powers, A. C., May 1 2018, In : Pancreas. 47, 5, p. 516-525 10 p.

Research output: Contribution to journalArticle

National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Pancreatic Neoplasms
Adenocarcinoma
Obesity
Inflammation

Vaccine therapy and immunotherapy for pancreatic cancer

Zheng, L. & Jaffee, E., Apr 11 2018, Pancreatic Cancer. Springer New York, p. 1461-1505 45 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Active Immunotherapy
Pancreatic Neoplasms
Immunotherapy
Neoplasms
Clinical Trials

ZIP4 promotes pancreatic cancer progression by repressing ZO-1 and claudin-1 through a ZEB1-dependent transcriptional mechanism

Liu, M., Yang, J., Zhang, Y., Zhou, Z., Cui, X., Zhang, L., Fung, K. M., Zheng, W., Allard, F. D., Yee, E. U., Ding, K., Wu, H., Liang, Z., Zheng, L., Fernandez-Zapico, M. E., Li, Y. P., Bronze, M. S., Morris, K. T., Postier, R. G., Houchen, C. W. & 2 others, Yang, J. & Li, M., Jul 1 2018, In : Clinical Cancer Research. 24, 13, p. 3186-3196 11 p.

Research output: Contribution to journalArticle

Claudin-1
Pancreatic Neoplasms
Paxillin
Heterografts
Neoplasms
2017

Current Standards of Chemotherapy for Pancreatic Cancer

Saung, M. T. & Zheng, L., 2017, (Accepted/In press) In : Clinical Therapeutics.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Combination Drug Therapy
Drug Therapy
gemcitabine
Phase III Clinical Trials

DNA methylation in the tumor microenvironment

Zhang, M. W., Fujiwara, K., Che, X., Zheng, S. & Zheng, L., May 1 2017, In : Journal of Zhejiang University: Science B. 18, 5, p. 365-372 8 p.

Research output: Contribution to journalReview article

Tumor Microenvironment
DNA methylation
DNA Methylation
Tumors
neoplasms

Dual inhibition of Hedgehog and c-Met pathways for pancreatic cancer treatment

Rucki, A. A., Xiao, Q., Muth, S., Chen, J., Che, X., Kleponis, J., Sharma, R., Anders, R. A., Jaffee, E. & Zheng, L., Nov 1 2017, In : Molecular Cancer Therapeutics. 16, 11, p. 2399-2409 11 p.

Research output: Contribution to journalArticle

Hedgehogs
Pancreatic Neoplasms
Adenocarcinoma
gemcitabine
Tumor Burden

Hedgehog signaling stimulates Tenascin C to promote invasion of pancreatic ductal adenocarcinoma cells through Annexin A2

Foley, K., Muth, S., Jaffee, E. & Zheng, L., Feb 4 2017, (Accepted/In press) In : Cell Adhesion and Migration. p. 1-10 10 p.

Research output: Contribution to journalArticle

Annexins
Tenascin
Adenocarcinoma
Stromal Cells
Neoplasms

Hepatitis B virus infection and exposure among foreign-born asian americans in the U.S.

Juon, H. S., Kim, F., Strong, C., Park, E., Zheng, L., Li, Z. & Lee, S., Jan 1 2017, In : Hepatitis Monthly. 17, 1, p. 1-6 6 p., e43018.

Research output: Contribution to journalArticle

Asian Americans
Virus Diseases
Hepatitis B virus
Hepatitis B Surface Antigens
Hepatitis B

Heterogeneous stromal signaling within the tumor microenvironment controls the metastasis of pancreatic cancer

Rucki, A. A., Foley, K., Zhang, P., Xiao, Q., Kleponis, J., Wu, A. A., Sharma, R., Mo, G., Liu, A., Van Eyk, J., Jaffee, E. & Zheng, L., Jan 1 2017, In : Cancer Research. 77, 1, p. 41-52 12 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Pancreatic Neoplasms
Adenocarcinoma
Neoplasm Metastasis
Insulin-Like Growth Factor I

LncRNA-PAGBC acts as a microRNA sponge and promotes gallbladder tumorigenesis

Wu, X. S., Wang, F., Li, H. F., Hu, Y. P., Jiang, L., Zhang, F., Li, M. L., Wang, X. A., Jin, Y. P., Zhang, Y. J., Lu, W., Wu, W. G., Shu, Y. J., Weng, H., Cao, Y., Bao, R. F., Liang, H. B., Wang, Z., Zhang, Y. C., Gong, W. & 3 others, Zheng, L., Sun, S. H. & Liu, Y. B., Oct 1 2017, In : EMBO Reports. 18, 10, p. 1837-1853 17 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Porifera
Gallbladder
MicroRNAs
Gallbladder Neoplasms

Long-term survival benefit of upfront chemotherapy in patients with newly diagnosed borderline resectable pancreatic cancer

Shrestha, B., Sun, Y., Faisal, F., Kim, V., Soares, K., Blair, A., Herman, J. M., Narang, A., Dholakia, A. S., Rosati, L., Hacker-Prietz, A., Chen, L., Laheru, D., De Jesus-Acosta, A., Le, D., Donehower, R. C., Azad, N., Diaz, L. A., Murphy, A., Lee, V. & 11 others, Fishman, E. K., Hruban, R. H., Liang, T., Cameron, J. L., Makary, M. A., Weiss, M. J., Ahuja, N., He, J., Wolfgang, C., Huang, C. Y. & Zheng, L., Jul 1 2017, In : Cancer Medicine. 6, 7, p. 1552-1562 11 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Drug Therapy
Neoadjuvant Therapy
Survival
Adenocarcinoma

Microfluidic device for primary tumor spheroid isolation

Zhou, J., Su, J., Fu, X., Zheng, L. & Yin, Z., Aug 7 2017, In : Experimental Hematology and Oncology. 6, 1, 22.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Cell Culture Techniques
Neoplasms
Cellular Spheroids
Drug Discovery

Modified-FOLFIRINOX in metastatic pancreatic cancer: A prospective study in Chinese population

Li, X., Ma, T., Zhang, Q., Chen, Y. G., Guo, C. X., Shen, Y. N., Sun, P. W., Li, G. G., Gao, S. L., Que, R. S., Lou, J. Y., Yu, R. S., Yuan, Y., Wei, Q. C., Wei, S. M., Zhang, Y., Zheng, L., Bai, X. L. & Liang, T. B., Oct 10 2017, In : Cancer Letters. 406, p. 22-26 5 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Prospective Studies
oxaliplatin
irinotecan
Population

Modified staging classification for pancreatic neuroendocrine tumors on the basis of the American Joint Committee on Cancer and European Neuroendocrine Tumor Society Systems

Luo, G., Javed, A., Strosberg, J. R., Jin, K., Zhang, Y., Liu, C., Xu, J., Soares, K., Weiss, M. J., Zheng, L., Wolfgang, C., Cives, M., Wong, J., Wang, W., Sun, J., Shao, C., Tan, H., Li, J., Ni, Q., Shen, L. & 4 others, Chen, M., He, J., Chen, J. & Yu, X., Jan 20 2017, In : Journal of Clinical Oncology. 35, 3, p. 274-280 7 p.

Research output: Contribution to journalArticle

Neuroendocrine Tumors
Neoplasm Staging
Neoplasms
Registries

Multiplex Proximity Ligation Assay to Identify Potential Prognostic Biomarkers for Improved Survival in Locally Advanced Pancreatic Cancer Patients Treated With Stereotactic Body Radiation Therapy

Rao, A. D., Liu, Y., von Eyben, R., Hsu, C. C., Hu, C., Rosati, L. M., Parekh, A., Ng, K., Hacker-Prietz, A., Zheng, L., Pawlik, T. M., Laheru, D., Jaffee, E., Weiss, M. J., Le, D., Hruban, R. H., De Jesus-Acosta, A., Wolfgang, C., Narang, A., Chang, D. T. & 2 others, Koong, A. C. & Herman, J. M., Jan 1 2017, (Accepted/In press) In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journalArticle

biomarkers
Pancreatic Neoplasms
Ligation
proximity
radiation therapy

MYBL2 is a Potential Prognostic Marker that Promotes Cell Proliferation in Gallbladder Cancer

Liang, H. B., Cao, Y., Ma, Q., Shu, Y. J., Wang, Z., Zhang, F., Ye, Y. Y., Li, H. F., Xiang, S. S., Song, X. L., Xu, Y., Zhang, Y. C., Bao, R. F., Yuan, R. Y., Zhang, Y. J., Hu, Y. P., Jiang, L., Li, M. L., Wang, X. A., Wu, X. S. & 9 others, Wu, W. G., Zhao, S., Fand, Y., Cui, X. P., Lu, Y. S., Zhou, J., Zheng, L., Gong, W. & Liu, Y. B., Apr 17 2017, (Accepted/In press) In : Cellular Physiology and Biochemistry. p. 2117-2131 15 p.

Research output: Contribution to journalArticle

Gallbladder Neoplasms
Cell Proliferation
Nude Mice
Neoplasms
Cholecystitis

Olaparib in combination with irinotecan, cisplatin, and mitomycin c in patients with advanced pancreatic cancer

Yarchoan, M., Myzak, M. C., Johnson, B. A., De Jesus-Acosta, A., Le, D., Jaffee, E., Azad, N., Donehower, R. C., Zheng, L., Oberstein, P. E., Fine, R. L., Laheru, D. & Goggins, M. S., 2017, In : Oncotarget. 8, 27, p. 44073-44081 9 p.

Research output: Contribution to journalArticle

irinotecan
Mitomycin
Pancreatic Neoplasms
Cisplatin
Adenocarcinoma

Overcoming the resistance of pancreatic cancer to immune checkpoint inhibitors

Skelton, R. A., Javed, A., Zheng, L. & He, J., Jul 1 2017, In : Journal of Surgical Oncology. 116, 1, p. 55-62 8 p.

Research output: Contribution to journalReview article

Tumor Microenvironment
Pancreatic Neoplasms
Immunotherapy
T-Lymphocytes
Active Immunotherapy

Patterns, Timing, and Predictors of Recurrence Following Pancreatectomy for Pancreatic Ductal Adenocarcinoma

Groot, V. P., Rezaee, N., Wu, W., Cameron, J. L., Fishman, E. K., Hruban, R. H., Weiss, M. J., Zheng, L., Wolfgang, C. & He, J., Mar 23 2017, (Accepted/In press) In : Annals of Surgery.

Research output: Contribution to journalArticle

Pancreatectomy
Adenocarcinoma
Recurrence
Adjuvant Chemoradiotherapy
Adjuvant Chemotherapy