Lee J Martin

Professor

1984 …2020

Research output per year

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Research Output

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2000
Open Access

Apoptosis has a prolonged role in the neurodegeneration after hypoxic ischemia in the newborn rat

Nakajima, W., Ishida, A., Lange, M. S., Gabrielson, K. L., Wilson, M. A., Martin, L. J., Blue, M. E. & Johnston, M. V., Nov 1 2000, In : Journal of Neuroscience. 20, 21, p. 7994-8004 11 p.

Research output: Contribution to journalArticle

Neuronal death in newborn striatum after hypoxia-ischemia is necrosis and evolves with oxidative stress

Martin, L. J., Brambrink, A. M., Price, A. C., Kaiser, A., Agnew, D. M., Ichord, R. N. & Traystman, R. J., Jun 2000, In : Neurobiology of Disease. 7, 3, p. 169-191 23 p.

Research output: Contribution to journalArticle

p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis

Martin, L. J., Jan 1 2000, In : Neurobiology of Disease. 7, 6, p. 613-622 10 p.

Research output: Contribution to journalArticle

Selective regional loss of exocytotic presynaptic vesicle proteins in Alzheimer's disease brains

Sze, C. I., Bi, H., Kleinschmidt-Demasters, B. K., Filley, C. M. & Martin, L. J., Apr 15 2000, In : Journal of the Neurological Sciences. 175, 2, p. 81-90 10 p.

Research output: Contribution to journalArticle

The CA1 region of the human hippocampus is a hot spot in Alzheimer's disease

West, M. J., Kawas, C. H., Martin, L. J. & Troncoso, J. C., Jan 1 2000, In : Annals of the New York Academy of Sciences. 908, p. 255-259 5 p.

Research output: Contribution to journalArticle

1999

Effects of the AMPA receptor antagonist NBQX on outcome of newborn pigs after asphyxic cardiac arrest

Brambrink, A. M., Martin, J. L., Hanley, D. F., Becker, K. J., Koehler, R. C. & Traystman, R. J., Jan 1 1999, In : Journal of Cerebral Blood Flow and Metabolism. 19, 8, p. 927-938 12 p.

Research output: Contribution to journalArticle

Open Access

Fimbria-fornix transection and excitotoxicity produce similar neurodegeneration in the septum

Ginsberg, S. D., Portera-Cailliau, C. & Martin, L. J., Feb 1 1999, In : Neuroscience. 88, 4, p. 1059-1071 13 p.

Research output: Contribution to journalArticle

Laminar segregation of the cortical plate during corticogenesis is accompanied by changes in glutamate receptor expression

Furuta, A. & Martin, L. J., Apr 13 1999, In : Journal of Neurobiology. 39, 1, p. 67-80 14 p.

Research output: Contribution to journalArticle

Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis

Martin, L. J., Kaiser, A. & Price, A. C., Jan 1 1999, In : Journal of Neurobiology. 40, 2, p. 185-201 17 p.

Research output: Contribution to journalArticle

Open Access
1998

AMPA receptor protein in developing rat brain: Glutamate receptor-1 expression and localization change at regional, cellular, and subcellular levels with maturation

Martin, L. J., Furuta, A. & Blackstone, C. D., Jan 5 1998, In : Neuroscience. 83, 3, p. 917-928 12 p.

Research output: Contribution to journalArticle

Animal models and degenerative disorders of the human brain

Martin, L. J., Portera-Cailliau, C., Ginsberg, S. D. & Al-Abdulla, N. A., Nov 1 1998, In : Lab Animal. 27, 10, p. 18-25 8 p.

Research output: Contribution to journalArticle

Cognitive decline strongly correlates with cortical atrophy in Alzheimer's dementia

Mouton, P. R., Martin, L. J., Calhoun, M. E., Dal Forno, G. & Price, D. L., Sep 1 1998, In : Neurobiology of Aging. 19, 5, p. 371-377 7 p.

Research output: Contribution to journalArticle

Familial amyotrophic lateral sclerosis and Alzheimer's disease: Transgenic models

Wong, P. C., Borchelt, D. R., Lee, M. K., Pardo, C. A., Thinakaran, G., Martin, L. J., Sisodia, S. S. & Price, D. L., Dec 1 1998, In : Advances in experimental medicine and biology. 446, p. 145-159 15 p.

Research output: Contribution to journalArticle

Neuropathology of preclinical and clinical late-onset Alzheimer's disease

Troncoso, J. C., Cataldo, A. M., Nixon, R. A., Barnett, J. L., Lee, M. K., Checler, F., Fowler, D. R., Smialek, J. E., Crain, B., Martin, L. J. & Kawas, C. H., May 1 1998, In : Annals of neurology. 43, 5, p. 673-676 4 p.

Research output: Contribution to journalArticle

Occipital cortex ablation in adult rat causes retrograde neuronal death in the lateral geniculate nucleus that resembles apoptosis

Al-Abdulla, N. A., Portera-Cailliau, C. & Martin, L. J., May 21 1998, In : Neuroscience. 86, 1, p. 191-209 19 p.

Research output: Contribution to journalArticle

Protein kinase C expression and activity after global incomplete cerebral ischemia in dogs

Sieber, F. E., Traystman, R. J., Brown, P. R. & Martin, L. J., Jul 1998, In : Stroke. 29, 7, p. 1445-1453 9 p.

Research output: Contribution to journalArticle

Open Access

The competitive NMDA antagonist GPI 3000 (GPI) does not improve outcome after cardiac arrest in dog

Hetfaer, M., Chord, R., Martin, L. J., Hum, P., Castro, J. & Traystman, R. J., Dec 1 1998, In : Critical care medicine. 26, 1 SUPPL., p. A54

Research output: Contribution to journalArticle

Treatment with the competitive NMDA antagonist GPI 3000 does not improve outcome after cardiac arrest in dogs

Helfaer, M. A., Ichord, R. N., Martin, L. J., Hurn, P. D., Castro, A. & Traystman, R. J., Apr 1998, In : Stroke. 29, 4, p. 824-829 6 p.

Research output: Contribution to journalArticle

Open Access

Ultrastructural analysis of the progression of neurodegeneration in the septum following fimbria-fornix transection

Ginsberg, S. D. & Martin, L. J., Jun 18 1998, In : Neuroscience. 86, 4, p. 1259-1272 14 p.

Research output: Contribution to journalArticle

1997

Amyotrophic lateral sclerosis and Alzheimer's disease. Lessons from model systems

Price, D. L., Wong, P. C., Borchelt, D. R., Pardo, C. A., Thinakaran, G., Doan, A. P., Lee, M. K., Martin, L. J. & Sisodia, S. S., Sep 1 1997, In : Revue Neurologique. 153, 8-9, p. 484-495 12 p.

Research output: Contribution to journalArticle

Cellular and synaptic localization of the neuronal glutamate transporters excitatory amino acid transporter 3 and 4

Furuta, A., Martin, L. J., Lin, C. L. G., Dykes-Hoberg, M. & J. D. Rothstein, D. R., Oct 10 1997, In : Neuroscience. 81, 4, p. 1031-1042 12 p.

Research output: Contribution to journalArticle

Characterization of metabotropic glutamate receptor-mediated nitric oxide production in vivo

Bhardwaj, A., Northington, F. J., Martin, L. J., Hanley, D. F., Traystman, R. J. & Koehler, R. C., Feb 1997, In : Journal of Cerebral Blood Flow and Metabolism. 17, 2, p. 153-160 8 p.

Research output: Contribution to journalArticle

Open Access
Open Access

Excitotoxic neuronal death in the immature brain is an apoptosis- necrosis morphological continuum

Portera-Cailliau, C., Price, D. L. & Martin, L. J., Feb 3 1997, In : Journal of Comparative Neurology. 378, 1, p. 10-87 78 p.

Research output: Contribution to journalArticle

Glutamate transporter protein subtypes are expressed differentially during rat cns development

Furuta, A., Rothstein, J. D. & Martin, J. L., Nov 6 1997, In : Journal of Neuroscience. 17, 21, p. 8363-8375 13 p.

Research output: Contribution to journalArticle

Hyperaccumulation of FAD-linked presenilin 1 variants in vivo

Lee, M. K., Borchelt, D. R., Kim, G., Thinakaran, G., Slunt, H. H., Ratovitski, T., Martin, L. J., Kittur, A., Gandy, S., Levey, A. I., Jenkins, N., Copeland, N., Price, D. L. & Sisodia, S. S., Jul 1 1997, In : Nature medicine. 3, 7, p. 756-760 5 p.

Research output: Contribution to journalArticle

Hypoxia-ischemia causes abnormalities in glutamate transporters and death of astroglia and neurons in newborn striatum

Lee Martin, J., Brambrink, A. M., Lehmann, C., Portera-Cailliau, C., Koehler, R., Rothstein, J. & Traystman, R. J., Sep 1 1997, In : Annals of neurology. 42, 3, p. 335-348 14 p.

Research output: Contribution to journalArticle

Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease

Sze, C. I., Troncoso, J. C., Kawas, C., Mouton, P., Price, D. L. & Martin, L. J., Aug 1997, In : Journal of neuropathology and experimental neurology. 56, 8, p. 933-944 12 p.

Research output: Contribution to journalArticle

Open Access

Neither L-arginine nor L-NAME affects neurological outcome after global ischemia in cats

Kirsch, J. R., Bhardwaj, A., Martin, L. J., Hanley, D. F. & Traystman, R. J., Nov 1997, In : Stroke. 28, 11, p. 2259-2265 7 p.

Research output: Contribution to journalArticle

Ontogeny of non-NMDA glutamate receptors in rat barrel field cortex: I. Metabotropic receptors

Blue, M. E., Martin, L. J., Brennan, E. M. & Johnston, M. V., Sep 15 1997, In : Journal of Comparative Neurology. 386, 1, p. 16-28 13 p.

Research output: Contribution to journalArticle

Ontogeny of non-NMDA glutamate receptors in rat barrel field cortex: II. α-AMPA and kainate receptors

Brennan, E. M., Martin, L. J., Johnston, M. V. & Blue, M. E., Sep 15 1997, In : Journal of Comparative Neurology. 386, 1, p. 29-45 17 p.

Research output: Contribution to journalArticle

Primary sensory and forebrain motor systems in the newborn brain are preferentially damaged by hypoxia-ischemia

Martin, L. J., Brambrink, A., Koehler, R. C. & Traystman, R. J., Jan 13 1997, In : Journal of Comparative Neurology. 377, 2, p. 262-285 24 p.

Research output: Contribution to journalArticle

1996

Comparative evaluation of synaptophysin-based methods for quantification of synapses

Calhoun, M. E., Jucker, M., Martin, L. J., Thinakaran, G., Price, D. L. & Mouton, P. R., Jan 1 1996, In : Journal of Neurocytology. 25, 1, p. 821-828 8 p.

Research output: Contribution to journalArticle

Diabetic chronic hyperglycemia and neurologic outcome following global ischemia in dogs

Sieber, F. E., Martin, L. J., Randall Brown, P., Palmon, S. C. & Traystman, R. J., Jan 1 1996, In : Journal of Cerebral Blood Flow and Metabolism. 16, 6, p. 1230-1235 6 p.

Research output: Contribution to journalArticle

Open Access

Effect of AMPA receptor antagonist nbqx on neuronal survival in basal ganglia after asphymc cardiac arrest in neonatal pigs

Bramhrink, A. M., Martin, L. J., Hanley, D. F., Becker, K., Shaffher, H. D., Koehler, R. C. & Trayitman, R. J., Dec 1 1996, In : FASEB Journal. 10, 3, p. A302

Research output: Contribution to journalArticle

Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues

Lee, M. K., Slunt, H. H., Martin, L. J., Thinakaran, G., Kim, G., Gandy, S. E., Seeger, M., Koo, E., Price, D. L. & Sisodia, S. S., Dec 1 1996, In : Journal of Neuroscience. 16, 23, p. 7513-7525 13 p.

Research output: Contribution to journalArticle

Neuropathology in controls and demented subjects from the Baltimore longitudinal study of aging

Troncoso, J. C., Martin, L. J., Dal Forno, G. & Kawas, C. H., Jan 1 1996, In : Neurobiology of Aging. 17, 3, p. 365-371 7 p.

Research output: Contribution to journalArticle

Ontogeny of glutamate transporters in the sheep brain

Northington, F. J., Trayslman, R. J., Koehler, R. C., Rpthstein, J. D. & Martin, L. J., Dec 1 1996, In : FASEB Journal. 10, 3, p. A765

Research output: Contribution to journalArticle

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

Ohshima, T., Ward, J. M., Huh, C. G., Longenecker, G., Veeranna, Pant, H. C., Brady, R. O., Martin, L. J. & Kulkarni, A. B., Oct 1 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 20, p. 11173-11178 6 p.

Research output: Contribution to journalArticle