Lee J Martin

Professor

1984 …2019
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Research Output 1984 2019

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1984

Cytophotometric analyses of brain neuronal RNA in soman intoxicated rabbits

Doebler, J. A., Wall, T. J., Moore, R. A., Martin, L. J., Shih, T. M. & Anthony, A., 1984, In : Toxicology. 32, 2, p. 153-163 11 p.

Research output: Contribution to journalArticle

Soman
Brain
RNA
Rabbits
Cytophotometry

Cytophotometric analyses of thalamic neuronal RNA in soman intoxicated rats

Martin, L. J., Doebler, J. A., Shih, T. M. & Anthony, A., Oct 8 1984, In : Life Sciences. 35, 15, p. 1593-1600 8 p.

Research output: Contribution to journalArticle

Soman
Rats
RNA
Cholinergic Agents
Ventral Thalamic Nuclei

Effects of HI-6 on brain neuronal RNA and acetylcholinesterase: Metabolic responses during acute soman intoxication

Doebler, J. A., Wall, T. J., Martin, L. J., Shih, T. M. & Anthony, A., 1984, In : Toxicology. 33, 3-4, p. 311-322 12 p.

Research output: Contribution to journalArticle

Soman
Acetylcholinesterase
Brain
RNA
Atropine

Myocardial nucleic acid and chromatin changes in soman toxicated rabbits

Martin, L. J., Doebler, J. & Anthony, A., 1984, In : Federation proceedings. 43, 3

Research output: Contribution to journalArticle

Soman
Nucleic Acids
Chromatin
Rabbits

Scanning cytophotometric analysis of myocardial nucleic acid and chromatin changes in soman toxicated rabbits

Martin, L. J., Doebler, J. A., Swisher, J. W., Shih, T. M. & Anthony, A., 1984, In : Cell Biochemistry and Function. 2, 4, p. 237-242 6 p.

Research output: Contribution to journalArticle

Soman
Nucleic Acids
Chromatin
RNA
Rabbits

Soman toxication in hypoxia acclimated rats: Alterations in brain neuronal RNA and survival

Doebler, J. A., Wall, T. J., Moore, R. A., Martin, L. J., Shih, T. M. & Anthony, A., Sep 1984, In : Neurochemical Research. 9, 9, p. 1239-1252 14 p.

Research output: Contribution to journalArticle

Soman
Rats
Brain
RNA
Acetylcholinesterase
1985

Cytophotometric analyses of mesencephalic reticular formation neuronal RNA in soman intoxicated rats

Doebler, J. A., Martin, L. J., Shih, T. M. & Anthony, A., 1985, In : Neurochemistry International. 7, 3, p. 415-420 6 p.

Research output: Contribution to journalArticle

Soman
Lethal Dose 50
RNA
Cholinergic Agents
Cytophotometry

Effects of diazepam on soman-induced brain neuronal RNA depletion and lethality in rats

Doebler, J. A., Wall, T. J., Martin, L. J., Shih, T. M. A. & Anthony, A., Mar 18 1985, In : Life Sciences. 36, 11, p. 1107-1115 9 p.

Research output: Contribution to journalArticle

Soman
Diazepam
Rats
Brain
RNA

Effects of HI-6 and pralidoxime on neuronal RNA in thalamic cholinergic sites

Martin, L. J., Doebler, J. A. & Anthony, A., 1985, In : Journal of the Neurological Sciences. 71, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Soman
Cholinergic Agents
Ventral Thalamic Nuclei
RNA
Oximes

Protective effect of diazepam pretreatment on soman-induced brain lesion formation

Martin, L. J., Doebler, J. A., Shih, T. M. & Anthony, A., Jan 28 1985, In : Brain Research. 325, 1-2, p. 287-289 3 p.

Research output: Contribution to journalArticle

Soman
Diazepam
Brain
Antidotes
Injections
1986

Brain neuronal chromatin responses in acute soman intoxicated rats

Martin, L. J., Doebler, J. A., Wall, T. J., Shih, T. M. & Anthony, A., Aug 1986, In : Neurochemical Research. 11, 8, p. 1203-1215 13 p.

Research output: Contribution to journalArticle

Soman
Chromatin
Rats
Brain
Acetylcholinesterase

Cytophotometric analysis of neuronal chromatin and RNA changes in oxotremorine-treated rats

Martin, L. J., Doebler, J. A. & Anthony, A., 1986, In : Experimental Biology and Medicine. 181, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

Oxotremorine
Chromatin
Rats
RNA
DNA

Perikaryal RNA changes within neurons of the caudate-putamen and substantia nigra in soman intoxicated rats

Martin, L. J., Doebler, J. A. & Anthony, A., 1986, In : Neurochemistry International. 9, 1, p. 121-126 6 p.

Research output: Contribution to journalArticle

Soman
Putamen
Substantia Nigra
RNA
Neurons

Quantitative cytophotometric analysis of brain neuronal RNA and protein changes in acute T-2 mycotoxin poisoned rats

Martin, L. J., Morse, J. D. & Anthony, A., 1986, In : Toxicon. 24, 9, p. 933-941 9 p.

Research output: Contribution to journalArticle

Mycotoxins
Rats
Brain
RNA
T-2 Toxin

Scanning cytophotometric analysis of brain neuronal nuclear chromatin changes in acute T-2 toxin-treated rats

Martin, L. J., Doebler, J. A. & Anthony, A., Sep 15 1986, In : Toxicology and Applied Pharmacology. 85, 2, p. 207-214 8 p.

Research output: Contribution to journalArticle

T-2 Toxin
Chromatin
Rats
Brain
Scanning
1987

Effects of sodium fluoride on uptake of T-2 mycotoxin in cultured cells

Trusal, L. R. & Martin, L. J., 1987, In : Toxicon. 25, 7, p. 705-711 7 p.

Research output: Contribution to journalArticle

Sodium Fluoride
Mycotoxins
Cultured Cells
Cells
T-2 Toxin
1988

Effects of oxotremorine on neuronal RNA and chromatin in thalamic cholinoceptive sites

Martin, L. J., Morse, J. D., Pritchard, G. A., Kim, Y. H. & Anthony, A., 1988, In : Journal of the Neurological Sciences. 86, 2-3, p. 159-169 11 p.

Research output: Contribution to journalArticle

Oxotremorine
Cholinergic Receptors
Chromatin
RNA
DNA

Topographic, non-collateralized basal forebrain projections to amygdala, hippocampus, and anterior cingulate cortex in the rhesus monkey

Koliatsos, V. E., Martin, L. J., Walker, L. C., Richardson, R. T., DeLong, M. R. & Price, D. L., Oct 25 1988, In : Brain Research. 463, 1, p. 133-139 7 p.

Research output: Contribution to journalArticle

Gyrus Cinguli
Amygdala
Macaca mulatta
Hippocampus
Neurons
1989

Cellular/molecular biological studies of brain abnormalities in Alzheimer's disease and animal models

Price, D. L., Koo, E. H., Sisodia, S. S., Walker, L. C., Martin, L. J. & Cork, L. C., Mar 1989, In : Journal of Neural Transmission - Parkinson's Disease and Dementia Section. 1, 1-2, p. 13 1 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Animal Models
Brain
1990

Neuronal disorders: Studies of animal models and human diseases

Price, D. L., Sisodia, S. S., Koo, E. H., Muma, N. A., Kitt, C. A., Walker, L. C., Martin, L. J., Troncoso, J. C., Griffin, J. W., Hoffman, P. N. & Cork, L. C., 1990, In : Toxicologic Pathology. 18, 1 II, p. 128-137 10 p.

Research output: Contribution to journalArticle

Animal Disease Models
Neurons
Animals
Neurology
Peripheral Nervous System

Neuronal responses to injury and aging: Lessons from animal models

Price, D. L., Koo, E. H., Sisodia, S. S., Martin, L. J., Koliatsos, V. E., Muma, N. A., Walker, L. C. & Cork, L. C., 1990, In : Progress in Brain Research. 86, p. 297-308 12 p.

Research output: Contribution to journalArticle

Animal Models
Alzheimer Disease
Wounds and Injuries
Brain
Cytoskeleton

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport

Koo, E. H., Sisodia, S. S., Archer, D. R., Martin, L. J., Weidemann, A., Beyreuther, K., Fischer, P., Masters, C. L. & Price, D. L., 1990, In : Proceedings of the National Academy of Sciences of the United States of America. 87, 4, p. 1561-1565 5 p.

Research output: Contribution to journalArticle

Axonal Transport
Amyloid beta-Protein Precursor
Alzheimer Disease
Amyloid Plaques
Brain
Pineal Gland
Intermediate Filaments
Alzheimer Disease
Antigens
Amyloid
1991

Aged non-human primates: An animal model of age-associated neurodegenerative disease

Price, D. L., Martin, L. J., Sisodia, S. S., Wagster, M. V., Koo, E. H., Walker, L. C., Koliatsos, V. E. & Cork, L. C., 1991, In : Brain Pathology. 1, 4, p. 287-296 10 p.

Research output: Contribution to journalArticle

Neurodegenerative Diseases
Primates
Animal Models
Amyloid Plaques
Nerve Growth Factor

Amyloid precursor protein in aged nonhuman primates

Martin, L. J., Sisodia, S. S., Koo, E. H., Cork, L. C., Dellovade, T. L., Weidemann, A., Beyreuther, K., Masters, C. & Price, D. L., 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 4, p. 1461-1465 5 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Primates
Amyloid Plaques
Axons
Neurites

Amyloid-related proteins and nerve growth factor in Alzheimer's disease and animal models

Price, D. L., Koliatsos, V. E., Sisodia, S. S., Koo, E. H., Martin, L. J., Walker, L. C., Applegate, M. D. & Cork, L. C., 1991, In : Clinical Neuropharmacology. 14, SUPPL. 1

Research output: Contribution to journalArticle

Amyloidogenic Proteins
Cholinergic Neurons
Nerve Growth Factor
Amyloid
Alzheimer Disease

Regulation and genetic control of brain amyloid

Gajdusek, D. C., Beyreuther, K., Brown, P., Cork, L. C., Cunningham, D. D., Frangione, B., Gibbs, C. J., Goldfarb, L. G., Goldgaber, D., Hsiao, K. K., Koo, E. H., Martin, L. J., Masters, C. L., Odenwald, W. F., Price, D. L., Prusiner, S. B., Ruddle, F. H., Safar, J., Scangos, G., Schmechel, D. E. & 9 others, Shashikant, C. S., Shlichta, P. J., Sisodia, S. S., Trapp, B. D., Unterbeck, A., Van Nostrand, W. E., Violette, S. M., Walker, L. C. & Wirak, D., 1991, In : Brain Research Reviews. 16, 1, p. 83-114 32 p.

Research output: Contribution to journalArticle

Social deprivation of infant rhesus monkeys alters the chemoarchitecture of the brain: I. Subcortical regions

Martin, L. J., Spicer, D. M., Lewis, M. H., Gluck, J. P. & Cork, L. C., 1991, In : Journal of Neuroscience. 11, 11, p. 3344-3358 15 p.

Research output: Contribution to journalArticle

Macaca mulatta
Haplorhini
Brain
Corpus Striatum
Tyrosine 3-Monooxygenase

The bed nucleus-amygdala continuum in human and monkey

Martin, L. J., Martin, L. J., Dellovade, T. L. & Price, D. L., 1991, In : Journal of Comparative Neurology. 309, 4, p. 445-485 41 p.

Research output: Contribution to journalArticle

Septal Nuclei
Amygdala
Haplorhini
Substantia Innominata
Intralaminar Thalamic Nuclei

The striatal mosaic in primates: Patterns of neuropeptide immunoreactivity differentiate the ventral striatum from the dorsal striatum

Martin, L. J., Hadfield, M. G., Dellovade, T. L. & Price, D. L., 1991, In : Neuroscience. 43, 2-3, p. 397-417 21 p.

Research output: Contribution to journalArticle

Leucine Enkephalin
Corpus Striatum
Substance P
Neuropeptides
Primates
1992

Age-associated inclusions in normal and transgenic mouse brain

Jucker, M., Walker, L. C., Martin, L. J., Kitt, C. A., Kleinman, H. K., Ingram, D. K., Price, D. L., Wirak, D., Bayney, R., Ramabhadran, T. V., Fracasso, R. P., Hart, J. T., Hauer, P. E., Hsiau, P., Pekar, S. K., Scangos, G. A., Trapp, B. D. & Unterbeck, A. J., 1992, In : Science. 255, 5050, p. 1443-1445 3 p.

Research output: Contribution to journalArticle

Amyloid beta-Peptides
Inbred C57BL Mouse
Transgenic Mice
Brain

Alzheimer's disease-type brain abnormalities in animal models.

Price, D. L., Martin, L. J., Sisodia, S. S., Walker, L. C. & Cork, L. C., 1992, In : Progress in Clinical and Biological Research. 379, p. 271-287 17 p.

Research output: Contribution to journalArticle

Animal Disease Models
Amyloid beta-Peptides
Macaca mulatta
Transgenic Mice
Alzheimer Disease

Amyloidosis in aging and Alzheimer's disease

Price, D. L., Walker, L. C., Martin, L. J. & Sisodia, S. S., 1992, In : American Journal of Pathology. 141, 4, p. 767-772 6 p.

Research output: Contribution to journalArticle

Animal Disease Models
Genetically Modified Animals
Amyloid beta-Protein Precursor
Amyloidosis
Macaca mulatta

Biochemical characterization and localization of a non-N-methyl-D-aspartate glutamate receptor in rat brain

Blackstone, C. D., Moss, S. J., Martin, L. J., Levey, A. I., Price, D. L. & Huganir, R. L., Mar 1992, In : Journal of Neurochemistry. 58, 3, p. 1118-1126 9 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Synaptic Membranes
Propionates
Glutamate Receptors
Cell membranes

Cellular localization of a metabotropic glutamate receptor in rat brain

Martin, L. J., Blackstone, C. D., Huganir, R. L. & Price, D. L., 1992, In : Neuron. 9, 2, p. 259-270 12 p.

Research output: Contribution to journalArticle

Metabotropic Glutamate Receptors
Brain
AMPA Receptors
Isoxazoles
Parahippocampal Gyrus

Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis

Rothstein, J. D., Martin, L. J. & Kuncl, R. W., May 28 1992, In : New England Journal of Medicine. 326, 22, p. 1464-1468 5 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Glutamic Acid
Spinal Cord
Brain
Synaptosomes

Immunological detection of glutamate receptor subtypes in human central nervous system

Blackstone, C. D., Levey, A. I., Martin, L. J., Price, D. L. & Huganir, R. L., Jun 1992, In : Annals of Neurology. 31, 6, p. 680-683 4 p.

Research output: Contribution to journalArticle

Glutamate Receptors
Central Nervous System
Nerve Tissue
Proteins
Neurotransmitter Receptor

Mesenteric mast cell degranulation in acute T-2 toxin poisoning

Doebler, J. A., Martin, L. J., Morse, J. D., Ballough, G. P., Strauss, J. A. & Anthony, A., 1992, In : Toxicology Letters. 62, 1, p. 33-38 6 p.

Research output: Contribution to journalArticle

T-2 Toxin
Cell Degranulation
Mast Cells
Poisoning
Granulation

Neuronal degeneration in human diseases and animal models

Price, D. L., Martin, L. J., Clatterbuck, R. E., Koliatsos, V. E., Sisodia, S. S., Walker, L. C. & Cork, L. C., 1992, In : Journal of Neurobiology. 23, 9, p. 1277-1294 18 p.

Research output: Contribution to journalArticle

Animal Disease Models
Nerve Growth Factor Receptor
Nerve Degeneration
Motor Neuron Disease
Nervous System Diseases

The G-protein-coupled receptor kinases βARK1 and βARK2 are widely distributed at synapses in rat brain

Arriza, J. L., Dawson, T. M., Simerly, R. B., Martin, L. J., Caron, M. G., Snyder, S. H. & Lefkowitz, R. J., 1992, In : Journal of Neuroscience. 12, 10, p. 4045-4055 11 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptor Kinases
Synapses
Adrenergic Receptors
Phosphotransferases
Neurotransmitter Receptor
1993

AMPA glutamate receptor subunits are differentially distributed in rat brain

Martin, L. J., Blackstone, C. D., Levey, A. I., Huganir, R. L. & Price, D. L., 1993, In : Neuroscience. 53, 2, p. 327-358 32 p.

Research output: Contribution to journalArticle

AMPA Receptors
Glutamate Receptors
Brain
Neurons
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Amyloid Plaques
Macaca
Amyloid
Cerebral Cortex
Primates

Cellular localizations of AMPA glutamate receptors within the basal forebrain magnocellular complex of rat and monkey

Martin, L. J., Blackstone, C. D., Levey, A. I., Huganir, R. L. & Price, D. L., 1993, In : Journal of Neuroscience. 13, 5, p. 2249-2263 15 p.

Research output: Contribution to journalArticle

AMPA Receptors
Glutamate Receptors
Haplorhini
Neurons
Cholinergic Neurons
Inositol 1,4,5-Trisphosphate Receptors
Type C Phospholipases
Second Messenger Systems
Basal Ganglia
Primates

The striatal mosaic in primates: Striosomes and matrix are differentially enriched in lonotropic glutamate receptor subunits

Martin, L. J., Blackstone, C. D., Huganir, R. L. & Price, D. L., 1993, In : Journal of Neuroscience. 13, 2, p. 782-792 11 p.

Research output: Contribution to journalArticle

Corpus Striatum
Glutamate Receptors
Primates
Caudate Nucleus
Nucleus Accumbens
1994

Impairment in mitochondrial cytochrome oxidase gene expression in Alzheimer disease

Chandrasekaran, K., Giordano, T., Brady, D. R., Stoll, J., Martin, L. J. & Rapoport, S. I., 1994, In : Molecular Brain Research. 24, 1-4, p. 336-340 5 p.

Research output: Contribution to journalArticle

Electron Transport Complex IV
Alzheimer Disease
Gene Expression
Brain
Messenger RNA

Localization of neuronal and glial glutamate transporters

Rothstein, J. D., Martin, L., Levey, A. I., Dykes-Hoberg, M., Jin, L., Wu, D., Nash, N. & Kuncl, R. W., 1994, In : Neuron. 13, 3, p. 713-725 13 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
Neuroglia
Astrocytes
Neurons
Hippocampus
Amyloidogenic Proteins
Amyloid Plaques
Amyloid beta-Protein Precursor
Neuroglia
Cerebral Cortex
1995

Cellular and molecular biology of Alzheimer's disease and animal models

Sisodia, S. S., Martin, L. J., Walker, L. C., Borchelt, D. R. & Price, D. L., 1995, In : Neuroimaging Clinics of North America. 5, 1, p. 59-68 10 p.

Research output: Contribution to journalArticle

Serum Amyloid A Protein
Cell Biology
Molecular Biology
Alzheimer Disease
Animal Models

Global incomplete cerebral ischemia produces predominantly cortical neuronal injury

Sieber, F., Palmon, S. C., Traystman, R. J. & Martin, L. J., 1995, In : Stroke. 26, 11, p. 2091-2095 5 p.

Research output: Contribution to journalArticle

Brain Ischemia
Canidae
Ischemia
Wounds and Injuries