Lee J Martin

Professor

1984 …2020

Research output per year

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Research Output

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Article
2020
Open Access
2019
Open Access
2018

Amyloid β toxic conformer has dynamic localization in the human inferior parietal cortex in absence of amyloid plaques

Kageyama, Y., Saito, A., Pletnikova, O., Rudow, G. L., Irie, Y., An, Y., Murakami, K., Irie, K., Resnick, S. M., Fowler, D. R., Martin, L. J. & Troncoso, J. C., Dec 1 2018, In : Scientific Reports. 8, 1, 16895.

Research output: Contribution to journalArticle

Delayed injury of hippocampal interneurons after neonatal hypoxia-ischemia and therapeutic hypothermia in a murine model

Chavez-Valdez, R., Emerson, P., Goffigan-Holmes, J., Kirkwood, A., Martin, L. J. & Northington, F., Aug 1 2018, In : Hippocampus. 28, 8, p. 617-630 14 p.

Research output: Contribution to journalArticle

Proteasome biology is compromised in white matter after asphyxic cardiac arrest in neonatal piglets

Santos, P. T., O’brien, C. E., Chen, M. W., Hopkins, C. D., Adams, S., Kulikowicz, E., Singh, R., Koehler, R. C., Martin, L. J. & Lee, J. K., Oct 1 2018, In : Journal of the American Heart Association. 7, 20, e009415.

Research output: Contribution to journalArticle

2016

Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer’s mouse model

LaClair, K. D., Donde, A., Ling, J. P., Jeong, Y. H., Chhabra, R., Martin, L. J. & Wong, P. C., Dec 1 2016, In : Acta Neuropathologica. 132, 6, p. 859-873 15 p.

Research output: Contribution to journalArticle

Hypothermia and Rewarming Activate a Macroglial Unfolded Protein Response Independent of Hypoxic-Ischemic Brain Injury in Neonatal Piglets

Lee-Summers, J., Wang, B., Reyes, M., Armstrong, J. S., Kulikowicz, E., Santos, P., Lee, J. H., Koehler, R. C. & Martin, L. J., Sep 14 2016, (Accepted/In press) In : Developmental Neuroscience.

Research output: Contribution to journalArticle

White matter apoptosis is increased by delayed hypothermia and rewarming in a neonatal piglet model of hypoxic ischemic encephalopathy

Wang, B., Armstrong, J. S., Reyes, M., Kulikowicz, E., Lee, J. H., Spicer, D., Bhalala, U., Yang, Z. J., Koehler, R. C., Martin, L. J. & Lee, J. K., Mar 1 2016, In : Neuroscience. 316, p. 296-310 15 p.

Research output: Contribution to journalArticle

2015

Additive Neuroprotection of a 20-HETE Inhibitor with Delayed Therapeutic Hypothermia after Hypoxia-Ischemia in Neonatal Piglets

Zhu, J., Wang, B., Lee, J. H., Armstrong, J. S., Kulikowicz, E., Bhalala, U. S., Martin, L. J., Koehler, R. C. & Yang, Z. J., Jul 25 2015, In : Developmental Neuroscience. 37, 4-5, p. 376-389 14 p.

Research output: Contribution to journalArticle

Apparent diffusion coefficient scalars correlate with near-Infrared spectroscopy markers of cerebrovascular autoregulation in neonates cooled for perinatal hypoxic-Ischemic injury

Tekes, A., Poretti, A., Scheurkogel, M. M., Huisman, T. A. G. M., Howlett, J. A., Alqahtani, E., Lee, J. H., Parkinson, C., Shapiro, K., Chung, S. E., Jennings, J. M., Gilmore, M. M., Hogue, C. W., Martin, L. J., Koehler, R. C., Northington, F. J. & Lee, J. K., Jan 1 2015, In : American Journal of Neuroradiology. 36, 1, p. 188-193 6 p.

Research output: Contribution to journalArticle

Hypoxia-ischemia and therapeutic hypothermia in the neonatal mouse brain - A longitudinal study

Burnsed, J. C., Chavez-Valdez, R., Hossain, M. S., Kesavan, K., Martin, L. J., Zhang, J. & Northington, F. J., Mar 16 2015, In : PloS one. 10, 3, e0118889.

Research output: Contribution to journalArticle

Rewarming from therapeutic hypothermia induces cortical neuron apoptosis in a swine model of neonatal hypoxic-ischemic encephalopathy

Wang, B., Armstrong, J. S., Lee, J. H., Bhalala, U., Kulikowicz, E., Zhang, H., Reyes, M., Moy, N., Spicer, D., Zhu, J., Yang, Z. J., Koehler, R. C., Martin, L. J. & Lee, J. K., May 5 2015, In : Journal of Cerebral Blood Flow and Metabolism. 35, 5, p. 781-793 13 p.

Research output: Contribution to journalArticle

2014

GNX-4728, a novel small molecule drug inhibitor of mitochondrial permeability transition, is therapeutic in a mouse model of amyotrophic lateral sclerosis

Martin, L. J., Fancelli, D., Wong, M., Niedzwiecki, M., Ballarini, M., Plyte, S. & Chang, Q., Dec 19 2014, In : Frontiers in Cellular Neuroscience. 8, DEC, 433.

Research output: Contribution to journalArticle

Induced pluripotent stem cells from familial alzheimer's disease patients differentiate into mature neurons with amyloidogenic properties

Mahairaki, V., Ryu, J., Peters, A., Chang, Q., Li, T., Park, T. S., Burridge, P. W., Talbot, C. C., Asnaghi, L., Martin, L. J., Zambidis, E. T. & Koliatsos, V. E., Dec 15 2014, In : Stem Cells and Development. 23, 24, p. 2996-3010 15 p.

Research output: Contribution to journalArticle

Skeletal muscle DNA damage precedes spinal motor neuron DNA damage in a mouse model of Spinal Muscular Atrophy (SMA)

Fayzullina, S. & Martin, L. J., Mar 25 2014, In : PloS one. 9, 3, e93329.

Research output: Contribution to journalArticle

The mitochondrial permeability transition pore regulates Parkinson's disease development in mutant α-synuclein transgenic mice

Martin, L. J., Semenkow, S., Hanaford, A. & Wong, M., May 1 2014, In : Neurobiology of Aging. 35, 5, p. 1132-1152 21 p.

Research output: Contribution to journalArticle

2013

Adenosine A2A receptor contributes to ischemic brain damage in newborn piglet

Yang, Z. J., Wang, B., Kwansa, H., Heitmiller, K. D., Hong, G., Carter, E. L., Jamrogowicz, J. L., Larson, A. C., Martin, L. J. & Koehler, R. C., Oct 1 2013, In : Journal of Cerebral Blood Flow and Metabolism. 33, 10, p. 1612-1620 9 p.

Research output: Contribution to journalArticle

Mitochondrial DNMT3A and DNA methylation in skeletal muscle and CNS of transgenic mouse models of ALS

Wong, M., Gertz, B., Chestnut, B. A. & Martin, L. J., Dec 25 2013, In : Frontiers in Cellular Neuroscience. 7, DEC, 279.

Research output: Contribution to journalArticle

Propofol-induced apoptosis of neurones and oligodendrocytes in fetal and neonatal rhesus macaque brain

Creeley, C., Dikranian, K., Dissen, G., Martin, L., Olney, J. & Brambrink, A., Jun 2013, In : British journal of anaesthesia. 110, SUPPL.1, p. i29-i38

Research output: Contribution to journalArticle

The olfactory bulb in newborn piglet is a reservoir of neural stem and progenitor cells

Martin, L. J., Katzenelson, A., Koehler, R. C. & Chang, Q., Nov 21 2013, In : PloS one. 8, 11, e81105.

Research output: Contribution to journalArticle

2012

Attenuation of neonatal ischemic brain damage using a 20-HETE synthesis inhibitor

Yang, Z. J., Carter, E. L., Kibler, K. K., Kwansa, H., Crafa, D. A., Martin, L. J., Roman, R. J., Harder, D. R. & Koehler, R. C., Apr 2012, In : Journal of Neurochemistry. 121, 1, p. 168-179 12 p.

Research output: Contribution to journalArticle

Early antioxidant treatment and delayed hypothermia after hypoxia-ischemia have no additive neuroprotection in newborn pigs

Ni, X., Yang, Z. J., Wang, B., Carter, E. L., Larson, A. C., Martin, L. J. & Koehler, R. C., Sep 2012, In : Anesthesia and Analgesia. 115, 3, p. 627-637 11 p.

Research output: Contribution to journalArticle

Inhibitory synaptic regulation of motoneurons: A new target of disease mechanisms in amyotrophic lateral sclerosis

Martin, L. J. & Chang, Q., Feb 2012, In : Molecular Neurobiology. 45, 1, p. 30-42 13 p.

Research output: Contribution to journalArticle

2011

Epigenetic regulation of motor neuron cell death through DNA methylation

Chestnut, B. A., Chang, Q., Price, A., Lesuisse, C., Wong, M. & Martin, L. J., Nov 16 2011, In : Journal of Neuroscience. 31, 46, p. 16619-16636 18 p.

Research output: Contribution to journalArticle

Glycine receptor channels in spinal motoneurons are abnormal in a transgenic mouse model of amyotrophic lateral sclerosis

Chang, Q. & Martin, L. J., Feb 23 2011, In : Journal of Neuroscience. 31, 8, p. 2815-2827 13 p.

Research output: Contribution to journalArticle

Open Access

Neuronal cell death in neonatal hypoxia-ischemia

Northington, F. J., Chavez-Valdez, R. & Martin, L. J., May 1 2011, In : Annals of neurology. 69, 5, p. 743-758 16 p.

Research output: Contribution to journalArticle

Neuroprotective effect of acid-sensing ion channel inhibitor psalmotoxin-1 after hypoxia-ischemia in newborn piglet striatum

Yang, Z. J., Ni, X., Carter, E. L., Kibler, K., Martin, L. J. & Koehler, R. C., Aug 1 2011, In : Neurobiology of Disease. 43, 2, p. 446-454 9 p.

Research output: Contribution to journalArticle

Striatal neuroprotection from neonatal hypoxia-ischemia in piglets by antioxidant treatment with EUK-134 or edaravone

Ni, X., Yang, Z. J., Carter, E. L., Martin, L. J. & Koehler, R. C., Oct 2011, In : Developmental Neuroscience. 33, 3-4, p. 299-311 13 p.

Research output: Contribution to journalArticle

The mitochondrial permeability transition pore regulates nitric oxide-mediated apoptosis of neurons induced by target deprivation

Martin, L. J., Adams, N. A., Pan, Y., Price, A. & Wong, M., Jan 5 2011, In : Journal of Neuroscience. 31, 1, p. 359-370 12 p.

Research output: Contribution to journalArticle