Lee J Martin

Professor

1984 …2020

Research output per year

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Research Output

2020
Open Access
2019
Open Access
2018

Amyloid β toxic conformer has dynamic localization in the human inferior parietal cortex in absence of amyloid plaques

Kageyama, Y., Saito, A., Pletnikova, O., Rudow, G. L., Irie, Y., An, Y., Murakami, K., Irie, K., Resnick, S. M., Fowler, D. R., Martin, L. J. & Troncoso, J. C., Dec 1 2018, In : Scientific Reports. 8, 1, 16895.

Research output: Contribution to journalArticle

Delayed injury of hippocampal interneurons after neonatal hypoxia-ischemia and therapeutic hypothermia in a murine model

Chavez-Valdez, R., Emerson, P., Goffigan-Holmes, J., Kirkwood, A., Martin, L. J. & Northington, F., Aug 1 2018, In : Hippocampus. 28, 8, p. 617-630 14 p.

Research output: Contribution to journalArticle

Proteasome biology is compromised in white matter after asphyxic cardiac arrest in neonatal piglets

Santos, P. T., O’brien, C. E., Chen, M. W., Hopkins, C. D., Adams, S., Kulikowicz, E., Singh, R., Koehler, R. C., Martin, L. J. & Lee, J. K., Oct 1 2018, In : Journal of the American Heart Association. 7, 20, e009415.

Research output: Contribution to journalArticle

2017

Neuronal cell death mechanisms relevant to humans: Rethinking modeling neonatal hypoxic-ischemic encephalopathy

Martin, L. J., Dec 21 2017, Fetal and Neonatal Brain Injury. Cambridge University Press, p. 21-35 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer’s mouse model

LaClair, K. D., Donde, A., Ling, J. P., Jeong, Y. H., Chhabra, R., Martin, L. J. & Wong, P. C., Dec 1 2016, In : Acta Neuropathologica. 132, 6, p. 859-873 15 p.

Research output: Contribution to journalArticle

Hypothermia and Rewarming Activate a Macroglial Unfolded Protein Response Independent of Hypoxic-Ischemic Brain Injury in Neonatal Piglets

Lee-Summers, J., Wang, B., Reyes, M., Armstrong, J. S., Kulikowicz, E., Santos, P., Lee, J. H., Koehler, R. C. & Martin, L. J., Sep 14 2016, (Accepted/In press) In : Developmental Neuroscience.

Research output: Contribution to journalArticle

White matter apoptosis is increased by delayed hypothermia and rewarming in a neonatal piglet model of hypoxic ischemic encephalopathy

Wang, B., Armstrong, J. S., Reyes, M., Kulikowicz, E., Lee, J. H., Spicer, D., Bhalala, U., Yang, Z. J., Koehler, R. C., Martin, L. J. & Lee-Summers, J., Mar 1 2016, In : Neuroscience. 316, p. 296-310 15 p.

Research output: Contribution to journalArticle

2015

Additive Neuroprotection of a 20-HETE Inhibitor with Delayed Therapeutic Hypothermia after Hypoxia-Ischemia in Neonatal Piglets

Zhu, J., Wang, B., Lee, J. H., Armstrong, J. S., Kulikowicz, E., Bhalala, U. S., Martin, L. J., Koehler, R. C. & Yang, Z. J., Jul 25 2015, In : Developmental Neuroscience. 37, 4-5, p. 376-389 14 p.

Research output: Contribution to journalArticle

Apparent diffusion coefficient scalars correlate with near-Infrared spectroscopy markers of cerebrovascular autoregulation in neonates cooled for perinatal hypoxic-Ischemic injury

Tekes, A., Poretti, A., Scheurkogel, M. M., Huisman, T. A. G. M., Howlett, J. A., Alqahtani, E., Lee, J. H., Parkinson, C., Shapiro, K., Chung, S. E., Jennings, J., Gilmore, M., Hogue, C. W., Martin, L. J., Koehler, R. C., Northington, F. & Lee-Summers, J., Jan 1 2015, In : American Journal of Neuroradiology. 36, 1, p. 188-193 6 p.

Research output: Contribution to journalArticle

Correction: Hypoxia-ischemia and therapeutic hypothermia in the neonatal mouse brain - A longitudinal study

Burnsed, J. C., Chavez-Valdez, R., Hossain, M. S., Kesavan, K., Martin, L. J. & Zhang, J., May 26 2015, In : PLoS One. 10, 5, e0129406.

Research output: Contribution to journalArticle

Hypoxia-ischemia and therapeutic hypothermia in the neonatal mouse brain - A longitudinal study

Burnsed, J. C., Chavez-Valdez, R., Hossain, M. S., Kesavan, K., Martin, L. J., Zhang, J. & Northington, F., Mar 16 2015, In : PLoS One. 10, 3, e0118889.

Research output: Contribution to journalArticle

Rewarming from therapeutic hypothermia induces cortical neuron apoptosis in a swine model of neonatal hypoxic-ischemic encephalopathy

Wang, B., Armstrong, J. S., Lee, J. H., Bhalala, U., Kulikowicz, E., Zhang, H., Reyes, M., Moy, N., Spicer, D., Zhu, J., Yang, Z. J., Koehler, R. C., Martin, L. J. & Lee-Summers, J., May 5 2015, In : Journal of Cerebral Blood Flow and Metabolism. 35, 5, p. 781-793 13 p.

Research output: Contribution to journalArticle

2014

GNX-4728, a novel small molecule drug inhibitor of mitochondrial permeability transition, is therapeutic in a mouse model of amyotrophic lateral sclerosis

Martin, L. J., Fancelli, D., Wong, M., Niedzwiecki, M., Ballarini, M., Plyte, S. & Chang, Q., Dec 19 2014, In : Frontiers in Cellular Neuroscience. 8, DEC, 433.

Research output: Contribution to journalArticle

Induced pluripotent stem cells from familial alzheimer's disease patients differentiate into mature neurons with amyloidogenic properties

Machairaki, V., Ryu, J., Peters, A., Chang, Q., Li, T., Park, T. S., Burridge, P. W., Talbot, C. C., Asnaghi, L., Martin, L. J., Zambidis, E. & Koliatsos, V. E., Dec 15 2014, In : Stem Cells and Development. 23, 24, p. 2996-3010 15 p.

Research output: Contribution to journalArticle

Skeletal muscle DNA damage precedes spinal motor neuron DNA damage in a mouse model of Spinal Muscular Atrophy (SMA)

Fayzullina, S. & Martin, L. J., Mar 25 2014, In : PLoS One. 9, 3, e93329.

Research output: Contribution to journalArticle

The mitochondrial permeability transition pore regulates Parkinson's disease development in mutant α-synuclein transgenic mice

Martin, L. J., Semenkow, S., Hanaford, A. & Wong, M., May 2014, In : Neurobiology of Aging. 35, 5, p. 1132-1152 21 p.

Research output: Contribution to journalArticle

2013

Aberrant Regulation of DNA Methylation in Amyotrophic Lateral Sclerosis: A New Target of Disease Mechanisms

Martin, L. J. & Wong, M., Oct 2013, In : Neurotherapeutics. 10, 4, p. 722-733 12 p.

Research output: Contribution to journalArticle

Adenosine A2A receptor contributes to ischemic brain damage in newborn piglet

Yang, Z. J., Wang, B., Kwansa, H., Heitmiller, K. D., Hong, G., Carter, E. L., Jamrogowicz, J. L., Larson, A. C., Martin, L. J. & Koehler, R. C., Oct 2013, In : Journal of Cerebral Blood Flow and Metabolism. 33, 10, p. 1612-1620 9 p.

Research output: Contribution to journalArticle

Mitochondrial DNMT3A and DNA methylation in skeletal muscle and CNS of transgenic mouse models of ALS

Wong, M., Gertz, B., Chestnut, B. A. & Martin, L. J., Dec 25 2013, In : Frontiers in Cellular Neuroscience. 7, DEC, 279.

Research output: Contribution to journalArticle

Propofol-induced apoptosis of neurones and oligodendrocytes in fetal and neonatal rhesus macaque brain

Creeley, C., Dikranian, K., Dissen, G., Martin, L. J., Olney, J. & Brambrink, A., Jun 2013, In : British Journal of Anaesthesia. 110, SUPPL.1

Research output: Contribution to journalArticle

The olfactory bulb in newborn piglet is a reservoir of neural stem and progenitor cells

Martin, L. J., Katzenelson, A., Koehler, R. C. & Chang, Q., Nov 21 2013, In : PLoS One. 8, 11, e81105.

Research output: Contribution to journalArticle

2012

Attenuation of neonatal ischemic brain damage using a 20-HETE synthesis inhibitor

Yang, Z. J., Carter, E. L., Kibler, K. K., Kwansa, H., Crafa, D. A., Martin, L. J., Roman, R. J., Harder, D. R. & Koehler, R. C., Apr 2012, In : Journal of Neurochemistry. 121, 1, p. 168-179 12 p.

Research output: Contribution to journalArticle

Biology of mitochondria in neurodegenerative diseases

Martin, L. J., 2012, In : Progress in Molecular Biology and Translational Science. 107, p. 355-415 61 p.

Research output: Contribution to journalArticle

Early antioxidant treatment and delayed hypothermia after hypoxia-ischemia have no additive neuroprotection in newborn pigs

Ni, X., Yang, Z. J., Wang, B., Carter, E. L., Larson, A. C., Martin, L. J. & Koehler, R. C., Sep 2012, In : Anesthesia and Analgesia. 115, 3, p. 627-637 11 p.

Research output: Contribution to journalArticle

Inhibitory synaptic regulation of motoneurons: A new target of disease mechanisms in amyotrophic lateral sclerosis

Martin, L. J. & Chang, Q., Feb 2012, In : Molecular Neurobiology. 45, 1, p. 30-42 13 p.

Research output: Contribution to journalArticle

Motor Neuron Diseases

Wong, P. C., Chiang, P. M., Martin, L. J., Koliatsos, V. E. & Price, D. L., 2012, Basic Neurochemistry. Elsevier, p. 801-814 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Epigenetic regulation of motor neuron cell death through DNA methylation

Chestnut, B. A., Chang, Q., Price, A., Lesuisse, C., Wong, M. & Martin, L. J., Nov 16 2011, In : Journal of Neuroscience. 31, 46, p. 16619-16636 18 p.

Research output: Contribution to journalArticle

Glycine receptor channels in spinal motoneurons are abnormal in a transgenic mouse model of amyotrophic lateral sclerosis

Chang, Q. & Martin, L. J., Feb 23 2011, In : Journal of Neuroscience. 31, 8, p. 2815-2827 13 p.

Research output: Contribution to journalArticle