Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Rhabdomyosarcoma Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Ewing's Sarcoma Medicine & Life Sciences
Osteosarcoma Medicine & Life Sciences
Sarcoma Medicine & Life Sciences
Insulin-Like Growth Factor II Medicine & Life Sciences
IGF Type 1 Receptor Medicine & Life Sciences
Somatomedins Medicine & Life Sciences

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Research Output 1977 2017

A phase I/II trial and pharmacokinetic study of mithramycin in children and adults with refractory Ewing sarcoma and EWS–FLI1 fusion transcript

Grohar, P. J., Glod, J., Peer, C. J., Sissung, T. M., Arnaldez, F. I., Long, L., Figg, W. D., Whitcomb, P., Helman, L. J. & Widemann, B. C. Sep 1 2017 In : Cancer Chemotherapy and Pharmacology. 80, 3, p. 645-652 8 p.

Research output: Contribution to journalArticle

Plicamycin
Ewing's Sarcoma
Pharmacokinetics
Refractory materials
Fusion reactions

A simple and rapid UHPLC–MS/MS method for the quantitation of the dual aurora kinase A/B inhibitor SCH-1473759 in murine plasma

Ferraz Nogueira Filho, M. A., Peer, C. J., Nguyen, J., McCalla, A., Helman, L. & Figg, W. D. Jan 5 2017 In : Journal of Pharmaceutical and Biomedical Analysis. 132, p. 223-226 4 p.

Research output: Contribution to journalArticle

Aurora Kinase B
Aurora Kinases
Aurora Kinase A
Plasmas
Liquid-Liquid Extraction

Clinical activity of the γ-secretase inhibitor PF-03084014 in adults with desmoid tumors (aggressive fibromatosis)

Kummar, S., Coyne, G. O. S., Do, K. T., Turkbey, B., Meltzer, P. S., Polley, E., Choyke, P. L., Meehan, R., Vilimas, R., Horneffer, Y., Juwara, L., Lih, A., Choudhary, A., Mitchell, S. A., Helman, L. J., Doroshow, J. H. & Chen, A. P. May 10 2017 In : Journal of Clinical Oncology. 35, 14, p. 1561-1569 9 p.

Research output: Contribution to journalArticle

Aggressive Fibromatosis
Amyloid Precursor Protein Secretases
Neoplasms
Connective Tissue Cells
Germ-Line Mutation

Matrix screen identifies synergistic combination of PARP inhibitors and nicotinamide phosphoribosyltransferase (NAMPT) inhibitors in Ewing sarcoma

Heske, C. M., Davis, M. I., Baumgart, J. T., Wilson, K., Gormally, M. V., Chen, L., Zhang, X., Ceribelli, M., Duveau, D. Y., Guha, R., Ferrer, M., Arnaldez, F. I., Ji, J., Tran, H. L., Zhang, Y., Mendoza, A., Helman, L. J. & Thomas, C. J. Dec 1 2017 In : Clinical Cancer Research. 23, 23, p. 7301-7311 11 p.

Research output: Contribution to journalArticle

Nicotinamide Phosphoribosyltransferase
Ewing's Sarcoma
NAD
Pharmaceutical Preparations
Investigational Drugs

SARC006: Phase II Trial of Chemotherapy in Sporadic and Neurofibromatosis Type 1 Associated Chemotherapy-Naive Malignant Peripheral Nerve Sheath Tumors

Higham, C. S. , Steinberg, S. M. , Dombi, E. , Perry, A. , Helman, L. J. , Schuetze, S. M. , Ludwig, J. A. , Staddon, A. , Milhem, M. M. , Rushing, D. , Jones, R. L. , Livingston, M. , Goldman, S. , Moertel, C. , Wagner, L. , Janhofer, D. , Annunziata, C. M. , Reinke, D. , Long, L. , Viskochil, D. & 2 others Baker, L. & Widemann, B. C. 2017 In : Sarcoma. 2017, 8685638

Research output: Contribution to journalArticle

Neurofibromatosis 1
Neurilemmoma
Drug Therapy
Ifosfamide
Etoposide