Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Neoplasms Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Rhabdomyosarcoma Medicine & Life Sciences
Osteosarcoma Medicine & Life Sciences
Ewing's Sarcoma Medicine & Life Sciences
Growth Medicine & Life Sciences
Sarcoma Medicine & Life Sciences
Pediatrics Medicine & Life Sciences

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Research Output 1977 2017

A phase I/II trial and pharmacokinetic study of mithramycin in children and adults with refractory Ewing sarcoma and EWS–FLI1 fusion transcript

Grohar, P. J., Glod, J., Peer, C. J., Sissung, T. M., Arnaldez, F. I., Long, L., Figg, W. D., Whitcomb, P., Helman, L. J. & Widemann, B. C. Sep 1 2017 In : Cancer Chemotherapy and Pharmacology. 80, 3, p. 645-652 8 p.

Research output: Research - peer-reviewArticle

Plicamycin
Pharmacokinetics
Refractory materials
Fusion reactions
EWS-FLI fusion protein

A simple and rapid UHPLC–MS/MS method for the quantitation of the dual aurora kinase A/B inhibitor SCH-1473759 in murine plasma

Ferraz Nogueira Filho, M. A., Peer, C. J., Nguyen, J., McCalla, A., Helman, L. & Figg, W. D. Jan 5 2017 In : Journal of Pharmaceutical and Biomedical Analysis. 132, p. 223-226 4 p.

Research output: Research - peer-reviewArticle

Aurora Kinase B
Aurora Kinases
Aurora Kinase A
SCH 1473759
Plasmas

Clinical activity of the γ-secretase inhibitor PF-03084014 in adults with desmoid tumors (aggressive fibromatosis)

Kummar, S., Coyne, G. O. S., Do, K. T., Turkbey, B., Meltzer, P. S., Polley, E., Choyke, P. L., Meehan, R., Vilimas, R., Horneffer, Y., Juwara, L., Lih, A., Choudhary, A., Mitchell, S. A., Helman, L. J., Doroshow, J. H. & Chen, A. P. May 10 2017 In : Journal of Clinical Oncology. 35, 14, p. 1561-1569 9 p.

Research output: Research - peer-reviewArticle

Aggressive Fibromatosis
Amyloid Precursor Protein Secretases
Neoplasms
2-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-3-ylamino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide
Therapeutics

SARC006: Phase II Trial of Chemotherapy in Sporadic and Neurofibromatosis Type 1 Associated Chemotherapy-Naive Malignant Peripheral Nerve Sheath Tumors

Higham, C. S. , Steinberg, S. M. , Dombi, E. , Perry, A. , Helman, L. J. , Schuetze, S. M. , Ludwig, J. A. , Staddon, A. , Milhem, M. M. , Rushing, D. , Jones, R. L. , Livingston, M. , Goldman, S. , Moertel, C. , Wagner, L. , Janhofer, D. , Annunziata, C. M. , Reinke, D. , Long, L. , Viskochil, D. & 2 others Baker, L. & Widemann, B. C. 2017 In : Sarcoma. 2017, 8685638

Research output: Research - peer-reviewArticle

Neurofibromatosis 1
Neurilemmoma
Drug Therapy
Ifosfamide
Etoposide

Surgical Management of Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Pediatric and Wildtype GIST Clinic

Weldon, C. B., Madenci, A. L., Boikos, S. A., Janeway, K. A., George, S., Von Mehren, M., Pappo, A. S., Schiffman, J. D., Wright, J., Trent, J. C., Pacak, K., Stratakis, C. A., Helman, L. J. & Quaglia, M. P. L. Feb 10 2017 In : Journal of Clinical Oncology. 35, 5, p. 523-528 6 p.

Research output: Research - peer-reviewArticle

Gastrointestinal Stromal Tumors
National Institutes of Health (U.S.)
Disease-Free Survival
Pediatrics
Disease Progression