Laura Hummers

Associate Professor

20022020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020

Vascular biomarkers and digital ulcerations in systemic sclerosis: results from a randomized controlled trial of oral treprostinil (DISTOL-1)

Mecoli, C. A., Perin, J., Van Eyk, J. E., Zhu, J., Fu, Q., Allmon, A. G., Rao, Y., Zeger, S., Wigley, F. M., Hummers, L. K. & Shah, A. A., Apr 1 2020, In : Clinical rheumatology. 39, 4, p. 1199-1205 7 p.

Research output: Contribution to journalArticle

2019

Collaborative National Quality and Efficacy Registry (CONQUER) for Scleroderma: outcomes from a multicenter US-based systemic sclerosis registry

Shanmugam, V. K., Frech, T. M., Steen, V. D., Hummers, L. K., Shah, A. A., Bernstein, E. J., Khanna, D., Gordon, J. K., Castelino, F. V., Chung, L., Hant, F. N., Startup, E., VanBuren, J. M., Evnin, L. B. & Assassi, S., Jan 1 2019, (Accepted/In press) In : Clinical rheumatology.

Research output: Contribution to journalArticle

Evaluation of risk factors for pseudo-obstruction in systemic sclerosis

Dein, E., Kuo, P. L., Hong, Y. S., Hummers, L., Mecoli, C. & McMahan, Z., Jan 1 2019, In : Seminars in Arthritis and Rheumatism.

Research output: Contribution to journalArticle

Generation of a Core Set of Items to Develop Classification Criteria for Scleroderma Renal Crisis Using Consensus Methodology

the Scleroderma Clinical Trials Consortium Scleroderma Renal Crisis Working Group, Jun 2019, In : Arthritis and Rheumatology. 71, 6, p. 964-971 8 p.

Research output: Contribution to journalArticle

Risk factors for mortality and cardiopulmonary hospitalization in systemic sclerosis patients at risk for pulmonary hypertension, in the pharos registry

Hsu, V. M., Chung, L., Hummers, L. K., Shah, A., Simms, R., Bolster, M., Hant, F. N., Silver, R. M., Fischer, A., Hinchcliff, M. E., Varga, J., Goldberg, A. Z., Derk, C. T., Schiopu, E., Khanna, D., Shapiro, L. S., Domsic, R. T., Medsger, T., Mayes, M. D., Furst, D. & 5 others, Csuka, M. E., Molitor, J. A., Saketkoo, L. A., Salazar, C. R. & Steen, V. D., Feb 1 2019, In : Journal of Rheumatology. 46, 2, p. 176-183 8 p.

Research output: Contribution to journalArticle

Open Access

Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma

Park, J. S., Oh, Y., Park, Y. J., Park, O., Yang, H., Slania, S., Hummers, L. K., Shah, A. A., An, H. T., Jang, J., Horton, M. R., Shin, J., Dietz, H. C., Song, E., Na, D. H., Park, E. J., Kim, K., Lee, K. C., Roschke, V. V., Hanes, J. & 2 others, Pomper, M. G. & Lee, S., Dec 1 2019, In : Nature communications. 10, 1, 1128.

Research output: Contribution to journalArticle

Open Access

Validation of the REVEAL Prognostic Equation and Risk Score Calculator in Incident Systemic Sclerosis–Associated Pulmonary Arterial Hypertension

on behalf of the PHAROS Investigators, Jan 1 2019, (Accepted/In press) In : Arthritis and Rheumatology.

Research output: Contribution to journalArticle

2018

ANCA-associated vasculitis in scleroderma: A renal perspective

Kant, S., Shah, A., Hummers, L., Wigley, F. & Geetha, D., Dec 1 2018, In : Clinical Nephrology. 90, 6, p. 413-418 6 p.

Research output: Contribution to journalArticle

Efficacy of Mycophenolate Mofetil and Oral Cyclophosphamide on Skin Thickness: Post Hoc Analyses From Two Randomized Placebo-Controlled Trials

Participants in the Scleroderma Lung Study I and members of the Scleroderma Lung Study II Research Group, Mar 2018, In : Arthritis Care and Research. 70, 3, p. 439-444 6 p.

Research output: Contribution to journalArticle

Gastrointestinal involvement in systemic sclerosis: diagnosis and management

McMahan, Z. & Hummers, L., Nov 1 2018, In : Current opinion in rheumatology. 30, 6, p. 533-540 8 p.

Research output: Contribution to journalArticle

Impact of Radiation Therapy on Scleroderma and Cancer Outcomes in Scleroderma Patients With Breast Cancer

Shah, D. J., Hirpara, R., Poelman, C. L., Woods, A., Hummers, L., Wigley, F., Wright, J., Parekh, A., Steen, V. D., Domsic, R. T. & Shah, A., Oct 1 2018, In : Arthritis Care and Research. 70, 10, p. 1517-1524 8 p.

Research output: Contribution to journalArticle

Rare loss of function variants in candidate genes and risk of colorectal cancer

NHLBI GO Exome Sequencing Project, Pulmonary Arterial Hypertension (PAH), Severe Asthma Research Program (SARP), Women’s Health Initiative (WHI), Anthropometry Project Team, Blood Count/Hematology Project Team, Blood Pressure Project Team, Data Flow Working Group, Early MI Project Team, ELSI Working Group, Executive Committee, Family Study Project Team, Lipids Project Team, Lung Project Team, Personal Genomics Project Team, Phenotype and Harmonization Working Group, Population Genetics and Statistical Analysis Working Group, Publications and Presentations Working Group, Quantitative Analysis Ad Hoc Task Group, Sequencing and Genotyping Working Group & 15 others, Steering Committee, Stroke Project Team, Structural Variation Working Group, Subclinical/Quantitative Project Team, Acute Lung Injury (ALI), Atherosclerosis Risk in Communities (ARIC), Cardiovascular Health Study (CHS), Chronic Obstructive Pulmonary Disease (COPDGene), Coronary Artery Risk Development in Young Adults (CARDIA), Cystic Fibrosis (CF), Early Pseudomonas Infection Control (EPIC), Framingham Heart Study (FHS), Jackson Heart Study (JHS), Lung Health Study (LHS) & Multi-Ethnic Study of Atherosclerosis (MESA), Oct 1 2018, In : Human genetics. 137, 10, p. 795-806 12 p.

Research output: Contribution to journalArticle

Spontaneous pneumomediastinum in limited cutaneous systemic sclerosis and myositis overlap

Dein, E. J., Lee, K., Timlin, H. & Hummers, L., Jan 1 2018, In : BMJ Case Reports. 2018, 224591.

Research output: Contribution to journalArticle

Symptoms of autonomic dysfunction in systemic sclerosis assessed by the COMPASS-31 questionnaire

Adler, B., Russell, J. W., Hummers, L. & McMahan, Z., Aug 1 2018, In : Journal of Rheumatology. 45, 8, p. 1145-1152 8 p.

Research output: Contribution to journalArticle

Vascular complications in systemic sclerosis: a prospective cohort study

Mecoli, C. A., Shah, A. A., Boin, F., Wigley, F. M. & Hummers, L. K., Sep 1 2018, In : Clinical rheumatology. 37, 9, p. 2429-2437 9 p.

Research output: Contribution to journalArticle

2017

Association of Fibrosing Myopathy in Systemic Sclerosis and Higher Mortality

Paik, J., Wigley, F., Shah, A., Corse, A. M., Casciola Rosen, L. A., Hummers, L. & Mammen, A. L., Nov 1 2017, In : Arthritis Care and Research. 69, 11, p. 1764-1770 7 p.

Research output: Contribution to journalArticle

Brief Report: Anti–RNPC-3 Antibodies As a Marker of Cancer-Associated Scleroderma

Shah, A., Xu, G., Rosen, A., Hummers, L., Wigley, F., Elledge, S. J. & Casciola Rosen, L. A., Jun 1 2017, In : Arthritis and Rheumatology. 69, 6, p. 1306-1312 7 p.

Research output: Contribution to journalArticle

Reply

Shah, A. A., Rosen, A., Hummers, L. K., Wigley, F. M., Xu, G., Elledge, S. J. & Casciola-Rosen, L., Sep 2017, In : Arthritis and Rheumatology. 69, 9, p. 1915-1916 2 p.

Research output: Contribution to journalLetter

Utility of B-type natriuretic peptides in the assessment of patients with systemic sclerosis-associated pulmonary hypertension in the PHAROS registry

Chung, L., Fairchild, R. M., Furst, D. E., Li, S., Alkassab, F., Bolster, M. B., Csuka, M. E., Derk, C. T., Domsic, R. T., Fischer, A., Frech, T. M., Gomberg-Maitland, M., Gordon, J. K., Hinchcliff, M., Hsu, V., Hummers, L., Khanna, D., Medsger, T. A., Molitor, J. A., Preston, I. R. & 8 others, Schiopu, E., Shapiro, L., Hant, F., Silver, R., Simms, R., Varga, J., Steen, V. D. & Zamanian, R. T., Jan 1 2017, In : Clinical and Experimental Rheumatology. 35, p. S106-S113

Research output: Contribution to journalArticle

2016

Biomarkers in Scleroderma: Progressing from Association to Clinical Utility

Ligon, C. & Hummers, L. K., Mar 1 2016, In : Current rheumatology reports. 18, 3, 17.

Research output: Contribution to journalReview article

Exhaled nitric oxide in pulmonary arterial hypertension associated with systemic sclerosis

Cao, Z., Mathai, S. C., Hummers, L. K., Shah, A. A., Wigley, F. M., Lechtzin, N., Hassoun, P. M. & Girgis, R. E., Dec 1 2016, In : Pulmonary Circulation. 6, 4, p. 545-550 6 p.

Research output: Contribution to journalArticle

Genetic susceptibility loci of idiopathic interstitial pneumonia do not represent risk for systemic sclerosis: A case control study in Caucasian patients

Wu, M., Assassi, S., Salazar, G. A., Pedroza, C., Gorlova, O. Y., Chen, W. V., Charles, J., Taing, M. L., Liao, K., Wigley, F. M., Hummers, L. K., Shah, A. A., Hinchcliff, M., Khanna, D., Schiopu, E., Phillips, K., Furst, D. E., Steen, V., Baron, M., Hudson, M. & 17 others, Zhou, X., Pope, J., Jones, N., Docherty, P., Khalidi, N. A., Robinson, D., Simms, R. W., Silver, R. M., Frech, T. M., Fessler, B. J., Fritzler, M. J., Molitor, J. A., Segal, B. M., Movahedian, M., Martín, J., Varga, J. & Mayes, M. D., Jan 20 2016, In : Arthritis Research and Therapy. 18, 1, 20.

Research output: Contribution to journalArticle

Identification of Rare Variants in ATP8B4 as a Risk Factor for Systemic Sclerosis by Whole-Exome Sequencing

Gao, L., Emond, M. J., Louie, T., Cheadle, C., Berger, A. E., Rafaels, N., Vergara, C., Kim, Y., Taub, M. A., Ruczinski, I., Mathai, S. C., Rich, S. S., Nickerson, D. A., Hummers, L. K., Bamshad, M. J., Hassoun, P. M., Mathias, R. A. & Barnes, K. C., Jan 1 2016, In : Arthritis and Rheumatology. 68, 1, p. 191-200 10 p.

Research output: Contribution to journalArticle

Right Ventricular Functional Reserve in Pulmonary Arterial Hypertension

Hsu, S., Houston, B. A., Tampakakis, E., Bacher, A. C., Rhodes, P. S., Mathai, S., Damico, R. L., Kolb, T. M., Hummers, L., Shah, A., McMahan, Z., Corona Villalobos, C., Zimmerman, S., Wigley, F., Hassoun, P. M., Kass, D. A. & Tedford, R. J., May 12 2016, (Accepted/In press) In : Circulation.

Research output: Contribution to journalArticle

Scleroderma mimics

Hummers, L. & Tyndall, A., Jan 1 2016, Scleroderma: From Pathogenesis to Comprehensive Management. Springer International Publishing, p. 115-123 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Symptomatic and Electrodiagnostic Features of Peripheral Neuropathy in Scleroderma

Paik, J., Mammen, A. L., Wigley, F., Shah, A., Hummers, L. & Polydefkis, M. J., Aug 1 2016, In : Arthritis Care and Research. 68, 8, p. 1150-1157 8 p.

Research output: Contribution to journalArticle

Thrombotic complications after radial arterial line placement in systemic sclerosis: A case series

Paik, J., Hirpara, R., Heller, J. A., Hummers, L., Wigley, F. & Shah, A., 2016, (Accepted/In press) In : Seminars in Arthritis and Rheumatism.

Research output: Contribution to journalArticle

Unique Abnormalities in Right Ventricular Longitudinal Strain in Systemic Sclerosis Patients

Mukherjee, M., Chung, S. E., Ton, V. K., Tedford, R. J., Hummers, L. K., Wigley, F. M., Abraham, T. P. & Shah, A. A., Jun 1 2016, In : Circulation: Cardiovascular Imaging. 9, 6, e003792.

Research output: Contribution to journalArticle

2015

Antinuclear antibody-negative systemic sclerosis

Salazar, G. A., Assassi, S., Wigley, F., Hummers, L., Varga, J., Hinchcliff, M., Khanna, D., Schiopu, E., Phillips, K., Furst, D. E., Steen, V., Baron, M., Hudson, M., Taillefer, S. S., Pope, J., Jones, N., Docherty, P., Khalidi, N. A., Robinson, D., Simms, R. W. & 14 others, Silver, R. M., Frech, T. M., Fessler, B. J., Molitor, J. A., Fritzler, M. J., Segal, B. M., Al-Kassab, F., Perry, M., Yang, J., Zamanian, S., Reveille, J. D., Arnett, F. C., Pedroza, C. & Mayes, M. D., Jun 1 2015, In : Seminars in Arthritis and Rheumatism. 44, 6, p. 680-686 7 p.

Research output: Contribution to journalArticle

Biomarkers of pulmonary hypertension in patients with scleroderma: A case-control study

McMahan, Z., Schoenhoff, F., Eyk, J. E., Wigley, F. M. & Hummers, L. K., Aug 6 2015, In : Arthritis Research and Therapy. 17, 1, 201.

Research output: Contribution to journalArticle

Intravenous immunoglobulin may be an effective therapy for refractory, active diffuse cutaneous systemic sclerosis

Poelman, C. L., Hummers, L. K., Wigley, F. M., Anderson, C., Boin, F. & Shah, A. A., Feb 1 2015, In : Journal of Rheumatology. 42, 2, p. 236-242 7 p.

Research output: Contribution to journalArticle

Oxalate nephropathy in systemic sclerosis: Case series and review of the literature

Ligon, C. B., Hummers, L. K. & McMahan, Z. H., Dec 2015, In : Seminars in Arthritis and Rheumatism. 45, 3, p. 315-320 6 p.

Research output: Contribution to journalArticle

Patient perspectives in OMERACT provide an anchor for future metric development and improved approaches to healthcare delivery in connective tissue disease related interstitial lung disease (CTD-ILD)

Mittoo, S., Frankel, S., Lesage, D., Strand, V., Shah, A. A., Christopher-Stine, L., Danoff, S., Hummers, L. K., Swigris, J. J., Huscher, D., Christensen, A. M., Cenac, S. L., Erbil, J. K., Ferguson, S., Garcia-Valladares, I., Grewal, H. K., Orbai, A. M., Smith, K. C., Tran, M., Bingham, C. O. & 3 others, Castelino, F. V., Fischer, A. & Saketkoo, L. A., Sep 1 2015, In : Current Respiratory Medicine Reviews. 11, 2, p. 175-183 9 p.

Research output: Contribution to journalArticle

2014

Connective tissue disease related interstitial lung diseases and idiopathic pulmonary fibrosis: Provisional core sets of domains and instruments for use in clinical trials

Saketkoo, L. A., Mittoo, S., Huscher, D., Khanna, D., Dellaripa, P. F., Distler, O., Flaherty, K. R., Frankel, S., Oddis, C. V., Denton, C. P., Fischer, A., Kowal-Bielecka, O. M., Lesage, D., Merkel, P. A., Phillips, K., Pittrow, D., Swigris, J., Antoniou, K., Baughman, R. P., Castelino, F. V. & 21 others, Christmann, R. B., Christopher-Stine, L., Collard, H. R., Cottin, V., Danoff, S., Highland, K. B., Hummers, L., Shah, A. A., Kim, D. S., Lynch, D. A., Miller, F. W., Proudman, S. M., Richeldi, L., Ryu, J. H., Sandorfi, N., Sarver, C., Wells, A. U., Strand, V., Matteson, E. L., Brown, K. K. & Seibold, J. R., May 2014, In : Thorax. 69, 5, p. 428-436 9 p.

Research output: Contribution to journalArticle

Consensus opinion of a North American Working Group regarding the classification of digital ulcers in systemic sclerosis

Baron, M., Chung, L., Gyger, G., Hummers, L., Khanna, D., Mayes, M. D., Pope, J. E., Shah, A. A., Steen, V. D., Steele, R., Tatibouet, S., Herrick, A., Müller-Ladner, U. & Hudson, M., Feb 1 2014, In : Clinical rheumatology. 33, 2, p. 207-214 8 p.

Research output: Contribution to journalArticle

Development of pulmonary hypertension in a high-risk population with systemic sclerosis in the Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma (PHAROS) cohort study

Hsu, V. M., Chung, L., Hummers, L. K., Wigley, F., Simms, R., Bolster, M., Silver, R., Fischer, A., Hinchcliff, M. E., Varga, J., Goldberg, A. Z., Derk, C. T., Schiopu, E., Khanna, D., Shapiro, L. S., Domsic, R. T., Medsger, T., Mayes, M. D., Furst, D., Csuka, M. E. & 3 others, Molitor, J. A., Alkassab, F. & Steen, V. D., Aug 2014, In : Seminars in Arthritis and Rheumatism. 44, 1, p. 55-62 8 p.

Research output: Contribution to journalArticle

Exposure to ACE inhibitors prior to the onset of scleroderma renal crisis-results from the international scleroderma renal crisis survey

Hudson, M., Baron, M., Tatibouet, S., Furst, D. E., Khanna, D., Hummers, L., Hachulla, E., Medsger, T., Steen, V., Alkassab, F., Johnson, S., Midtvedt, O., Szucs, G., Schiopu, E., Carreira, P. E., Derk, C. T., Distler, O., Inanc, M., Khalidi, N., Mahmud, T. H. & 38 others, Mayes, M. D., McKown, K., Proudman, S., Rudnicka, L., Seigel, S., Stein, J., Valentini, G., Yavuz, S., Arbillaga, H., Hazel, B., Schulz, J., Baker, M., Becker, M., Cabane, J., Chow, A., Christmann, R., Clements, P., Csuka, M. E., Hanke, K., Kötter, I., Jacobsen, S., Kur, J., Lally, E. V., Ligier, S., Mittoo, S., Peschken, C., De La Pena-Lefebvre, P. G., Queyrel, V., Silver, R., Simms, R., Sondergaard, K., Troyanov, Y., Turi, M. C., Varga, J., Vlachoyiannopoulos, P. G., Voskuyl, A. E., Yeadon, C. & Westhovens, R., Apr 2014, In : Seminars in Arthritis and Rheumatism. 43, 5, p. 666-672 7 p.

Research output: Contribution to journalArticle

Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis

Mayes, M. D., Bossini-Castillo, L., Gorlova, O., Martin, J. E., Zhou, X., Chen, W. V., Assassi, S., Ying, J., Tan, F. K., Arnett, F. C., Reveille, J. D., Guerra, S., Teruel, M., Carmona, F. D., Gregersen, P. K., Lee, A. T., López-Isac, E., Ochoa, E., Carreira, P., Simeón, C. P. & 55 others, Castellví, I., González-Gay, M. Á., Zhernakova, A., Padyukov, L., Alarcón-Riquelme, M., Wijmenga, C., Brown, M., Beretta, L., Riemekasten, G., Witte, T., Hunzelmann, N., Kreuter, A., Distler, J. H. W., Voskuyl, A. E., Schuerwegh, A. J., Hesselstrand, R., Nordin, A., Airó, P., Lunardi, C., Shiels, P., Van Laar, J. M., Herrick, A., Worthington, J., Denton, C., Wigley, F. M., Hummers, L. K., Varga, J., Hinchcliff, M. E., Baron, M., Hudson, M., Pope, J. E., Furst, D. E., Khanna, D., Phillips, K., Schiopu, E., Segal, B. M., Molitor, J. A., Silver, R. M., Steen, V. D., Simms, R. W., Lafyatis, R. A., Fessler, B. J., Frech, T. M., Alkassab, F., Docherty, P., Kaminska, E., Khalidi, N., Jones, H. N., Markland, J., Robinson, D., Broen, J., Radstake, T. R. D. J., Fonseca, C., Koeleman, B. P. & Martin, J., Jan 2 2014, In : American journal of human genetics. 94, 1, p. 47-61 15 p.

Research output: Contribution to journalArticle

International consensus criteria for the diagnosis of Raynaud's phenomenon

Maverakis, E., Patel, F., Kronenberg, D. G., Chung, L., Fiorentino, D., Allanore, Y., Guiducci, S., Hesselstrand, R., Hummers, L. K., Duong, C., Kahaleh, B., Macgregor, A., Matucci-Cerinic, M., Wollheim, F. A., Mayes, M. D. & Gershwin, M. E., Jan 1 2014, In : Journal of Autoimmunity. 48-49, p. 60-65 6 p.

Research output: Contribution to journalArticle

Pulmonary hypertension and interstitial lung disease within PHAROS: impact of extent of fibrosis and pulmonary physiology on cardiac haemodynamic parameters

Fischer, A., Swigris, J. J., Bolster, M. B., Chung, L., Csuka, M. E., Domsic, R., Frech, T., Hinchcliff, M., Hsu, V., Hummers, L., Gomberg-Maitland, M., Mathai, S., Simms, R. & Steen, V. D., Nov 1 2014, In : Clinical and Experimental Rheumatology. 32, 6

Research output: Contribution to journalArticle