Laura Ensign-Hodges

Associate Professor

20092019

Research output per year

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Research Output

  • 37 Article
  • 1 Conference contribution
  • 1 Editorial
2019

Conceptual design of a universal donor screening approach for vaginal microbiota transplant

Delong, K., Bensouda, S., Zulfiqar, F., Zierden, H. C., Hoang, T. M., Abraham, A. G., Coleman, J. S., Cone, R. A., Gravitt, P. E., Hendrix, C. W., Fuchs, E. J., Gaydos, C. A., Weld, E. D. & Ensign, L. M., Jan 1 2019, In : Frontiers in Cellular and Infection Microbiology. 9, AUG, 306.

Research output: Contribution to journalArticle

Open Access

Controlled release of corticosteroid with biodegradable nanoparticles for treating experimental autoimmune uveitis

Luo, L., Yang, J., Oh, Y., Hartsock, M. J., Xia, S., Kim, Y. C., Ding, Z., Meng, T., Eberhart, C. G., Ensign-Hodges, L., Thorne, J., Stark, W. J., Duh, E. J., Xu, Q. & Hanes, J. S., Feb 28 2019, In : Journal of Controlled Release. 296, p. 68-80 13 p.

Research output: Contribution to journalArticle

Controlled release of dexamethasone sodium phosphate with biodegradable nanoparticles for preventing experimental corneal neovascularization

Wang, B., Tang, Y., Oh, Y., Lamb, N. W., Xia, S., Ding, Z., Chen, B., Suarez, M. J., Meng, T., Kulkarni, V., Eberhart, C. G., Ensign-Hodges, L., Stark, W. J., Hanes, J. S. & Xu, Q., Apr 1 2019, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 17, p. 119-123 5 p.

Research output: Contribution to journalArticle

2018

Hypo-osmolar formulation of tenofovir (TFV) enema promotes uptake and metabolism of TFV in tissues, leading to prevention of SHIV/SIV infection

Xiao, P., Gumber, S., Marzinke, M. A., Date, A. A., Hoang, T., Hanes, J. S., Ensign-Hodges, L., Wang, L., Rohan, L., Fuchs, E., Hendrix, C. & Villinger, F., Jan 1 2018, In : Antimicrobial Agents and Chemotherapy. 62, 1, e01644-17.

Research output: Contribution to journalArticle

2017

Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation

Schneider, C. S., Xu, Q., Boylan, N. J., Chisholm, J., Tang, B. C., Schuster, B. S., Henning, A., Ensign-Hodges, L., Lee, E., Adstamongkonkul, P., Simons, B. W., Wang, S. Y. S., Gong, X., Yu, T., Boyle, M. P., Suk, J. S. & Hanes, J. S., Apr 1 2017, In : Science advances. 3, 4, e1601556.

Research output: Contribution to journalArticle

Preclinical evaluation of intravesical cisplatin nanoparticles for non–muscle-invasive bladder cancer

Kates, M., Date, A., Yoshida, T., Afzal, U., Kanvinde, P., Babu, T., Sopko, N. A., Matsui, H., Hahn, N., McConkey, D., Baras, A., Hanes, J. S., Ensign-Hodges, L. & Bivalacqua, T., Nov 1 2017, In : Clinical Cancer Research. 23, 21, p. 6592-6601 10 p.

Research output: Contribution to journalArticle

2016

Anti-PEG antibodies alter the mobility and biodistribution of densely PEGylated nanoparticles in mucus

Henry, C. E., Wang, Y. Y., Yang, Q., Hoang, T., Chattopadhyay, S., Hoen, T., Ensign-Hodges, L., Nunn, K. L., Schroeder, H., McCallen, J., Moench, T., Cone, R., Roffler, S. R. & Lai, S. K., Oct 1 2016, In : Acta Biomaterialia. 43, p. 61-70 10 p.

Research output: Contribution to journalArticle

Local enema treatment to inhibit FOLH1/GCPII as a novel therapy for inflammatory bowel disease

Date, A. A., Rais, R., Babu, T., Ortiz, J., Kanvinde, P., Thomas, A. G., Zimmermann, S. C., Gadiano, A. J., Halpert, G., Slusher, B. & Ensign-Hodges, L., Nov 24 2016, (Accepted/In press) In : Journal of Controlled Release.

Research output: Contribution to journalArticle

Mucus-Penetrating Nanosuspensions for Enhanced Delivery of Poorly Soluble Drugs to Mucosal Surfaces

Yu, T., Chisholm, J., Choi, W. J., Anonuevo, A., Pulicare, S., Zhong, W., Chen, M., Fridley, C., Lai, S. K., Ensign-Hodges, L., Suk, J. S. & Hanes, J. S., 2016, (Accepted/In press) In : Advanced healthcare materials.

Research output: Contribution to journalArticle

Nanoparticles coated with high molecular weight PEG penetrate mucus and provide uniform vaginal and colorectal distribution in vivo

Maisel, K., Reddy, M., Xu, Q., Chattopadhyay, S., Cone, R., Ensign-Hodges, L. & Hanes, J. S., Jun 1 2016, In : Nanomedicine. 11, 11, p. 1337-1343 7 p.

Research output: Contribution to journalArticle

Nanoparticles for oral delivery: Design, evaluation and state-of-the-art

Date, A. A., Hanes, J. S. & Ensign-Hodges, L., Feb 26 2016, (Accepted/In press) In : Journal of Controlled Release.

Research output: Contribution to journalArticle

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

Suk, J. S., Xu, Q., Kim, N., Hanes, J. S. & Ensign-Hodges, L., Apr 1 2016, In : Advanced Drug Delivery Reviews. 99, p. 28-51 24 p.

Research output: Contribution to journalArticle

2015

Editorial

Hanes, J. S., Ensign-Hodges, L., Rangaramanujam, K. & Suk, J. S., Dec 10 2015, In : Journal of Controlled Release. 219, p. 1 1 p.

Research output: Contribution to journalArticle

Enema ion compositions for enhancing colorectal drug delivery

Maisel, K., Chattopadhyay, S., Moench, T., Hendrix, C., Cone, R., Ensign-Hodges, L. & Hanes, J. S., May 17 2015, In : Journal of Controlled Release. 209, p. 280-287 8 p.

Research output: Contribution to journalArticle

Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo

Xu, Q., Ensign-Hodges, L., Boylan, N. J., Schön, A., Gong, X., Yang, J. C., Lamb, N. W., Cai, S., Yu, T., Freire, E. I. & Hanes, J. S., Sep 22 2015, In : ACS Nano. 9, 9, p. 9217-9227 11 p.

Research output: Contribution to journalArticle

Liposome-based mucus-penetrating particles (MPP) for mucosal theranostics: Demonstration of diamagnetic chemical exchange saturation transfer (diaCEST) magnetic resonance imaging (MRI)

Yu, T., Chan, K. W. Y., Anonuevo, A., Song, X., Schuster, B. S., Chattopadhyay, S., Xu, Q., Oskolkov, N., Patel, H., Ensign-Hodges, L., Van Zijl, P. C., Mcmahon, M. T. & Hanes, J. S., Feb 1 2015, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 11, 2, p. 401-405 5 p.

Research output: Contribution to journalArticle

Modulating Vibrio cholerae Quorum-Sensing-Controlled Communication Using Autoinducer-Loaded Nanoparticles

Lu, H. D., Spiegel, A. C., Hurley, A., Perez, L. J., Maisel, K., Ensign-Hodges, L., Hanes, J. S., Bassler, B. L., Semmelhack, M. F. & Prud'Homme, R. K., Apr 8 2015, In : Nano Letters. 15, 4, p. 2235-2241 7 p.

Research output: Contribution to journalArticle

Particle tracking in drug and gene delivery research: State-of-the-art applications and methods

Schuster, B. S., Ensign-Hodges, L., Allan, D. B., Suk, J. S. & Hanes, J. S., Aug 30 2015, In : Advanced Drug Delivery Reviews. 91, p. 70-91 22 p.

Research output: Contribution to journalArticle

2014

Nanoparticle-based drug delivery to the vagina: A review

Ensign-Hodges, L., Cone, R. & Hanes, J. S., Sep 28 2014, In : Journal of Controlled Release. 190, p. 500-514 15 p.

Research output: Contribution to journalArticle

Optimization of mucus penetrating particles and vehicle composition for improved mucosal surface drug delivery

Ensign-Hodges, L., Xu, Q., Tang, B., Wang, Y. Y., Cone, R. & Hanes, J. S., 2014, Nanoscale Science and Engineering Forum 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. AIChE, p. 2-4 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Pretreatment of human cervicovaginal mucus with pluronic F127 enhances nanoparticle penetration without compromising mucus barrier properties to herpes simplex virus

Ensign-Hodges, L., Lai, S. K., Wang, Y. Y., Yang, M., Mert, O., Hanes, J. S. & Cone, R., Dec 8 2014, In : Biomacromolecules. 15, 12, p. 4403-4409 7 p.

Research output: Contribution to journalArticle

2013
2012

A poly(ethylene glycol)-based surfactant for formulation of drug-loaded mucus penetrating particles

Mert, O., Lai, S. K., Ensign-Hodges, L., Yang, M., Wang, Y. Y., Wood, J. & Hanes, J. S., Feb 10 2012, In : Journal of Controlled Release. 157, 3, p. 455-460 6 p.

Research output: Contribution to journalArticle

Mucus penetrating nanoparticles: Biophysical tool and method of drug and gene delivery

Ensign-Hodges, L., Schneider, C., Suk, J. S., Cone, R. & Hanes, J. S., Jul 24 2012, In : Advanced Materials. 24, 28, p. 3887-3894 8 p.

Research output: Contribution to journalArticle

2009

The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles

Suk, J. S., Lai, S. K., Wang, Y. Y., Ensign-Hodges, L., Zeitlin, P. L., Boyle, M. P. & Hanes, J. S., May 2009, In : Biomaterials. 30, 13, p. 2591-2597 7 p.

Research output: Contribution to journalArticle