Laszlo Nagy

Professor

1991 …2019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1991 2019

Filter
Review article
2016

Is the mouse a good model of human PPARγ-related metabolic diseases?

Pap, A., Cuaranta-Monroy, I., Peloquin, M. & Nagy, L., Aug 1 2016, In : International Journal of Molecular Sciences. 17, 8, 1236.

Research output: Contribution to journalReview article

metabolic diseases
PPAR gamma
Metabolic Diseases
mice
Human Experimentation
2014

Causes and Pathophysiology of Heart Failure with Preserved Ejection Fraction

Kovács, Á., Papp, Z. & Nagy, L., Jan 1 2014, In : Heart Failure Clinics. 10, 3, p. 389-398 10 p.

Research output: Contribution to journalReview article

Diastolic Heart Failure
Systolic Heart Failure
Sex Distribution
Vascular Stiffness
Aortic Valve Stenosis

The intriguing complexities of mammalian gene regulation: How to link enhancers to regulated genes. Are we there yet?

Daniel, B., Nagy, G. & Nagy, L., Aug 1 2014, In : FEBS Letters. 588, 15, p. 2379-2391 13 p.

Research output: Contribution to journalReview article

Gene expression
Genes
Gene Regulatory Networks
Gene Expression Regulation
Genomics
2013

Nuclear receptor mediated mechanisms of macrophage cholesterol metabolism

Nagy, Z. S., Czimmerer, Z. & Nagy, L., Apr 10 2013, In : Molecular and Cellular Endocrinology. 368, 1-2, p. 85-98 14 p.

Research output: Contribution to journalReview article

Macrophages
Cytoplasmic and Nuclear Receptors
Metabolism
Cholesterol
Lipids

Nuclear receptors as regulators of stem cell and cancer stem cell metabolism

Simandi, Z., Cuaranta-Monroy, I. & Nagy, L., Jan 1 2013, In : Seminars in Cell and Developmental Biology. 24, 10-12, p. 716-723 8 p.

Research output: Contribution to journalReview article

Neoplastic Stem Cells
Cytoplasmic and Nuclear Receptors
Stem Cells
Embryonic Development
Physiological Phenomena
2012

Nuclear hormone receptors enable macrophages and dendritic cells to sense their lipid environment and shape their immune response

Nagy, L., Szanto, A., Szatmari, I. & Széles, L., Apr 1 2012, In : Physiological Reviews. 92, 2, p. 739-789 51 p.

Research output: Contribution to journalReview article

Cytoplasmic and Nuclear Receptors
Dendritic Cells
Retinoid X Receptors
Macrophages
Lipids
2011

Gene expression profiles in peripheral blood for the diagnosis of autoimmune diseases

Mesko, B., Poliska, S. & Nagy, L., Apr 1 2011, In : Trends in Molecular Medicine. 17, 4, p. 223-233 11 p.

Research output: Contribution to journalReview article

Gene Expression Profiling
Transcriptome
Autoimmune Diseases
Chronic Disease
Decision Trees

PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation

Varga, T., Czimmerer, Z. & Nagy, L., Aug 1 2011, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1812, 8, p. 1007-1022 16 p.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Lipid Metabolism
Transcription Factors
Fatty Acids
Cytoplasmic and Nuclear Receptors
2009

Oxysterol signaling links cholesterol metabolism and inflammation via the liver X receptor in macrophages

Töröcsik, D., Szanto, A. & Nagy, L., Jun 1 2009, In : Molecular Aspects of Medicine. 30, 3, p. 134-152 19 p.

Research output: Contribution to journalReview article

Macrophages
Metabolism
Liver
Cholesterol
Inflammation
2008
PPAR gamma
Cytoplasmic and Nuclear Receptors
Lipid Metabolism
Immunity
Transcription Factors

Nuclear receptor signalling in dendritic cells connects lipids, the genome and immune function

Szatmari, I. & Nagy, L., Sep 17 2008, In : EMBO Journal. 27, 18, p. 2353-2362 10 p.

Research output: Contribution to journalReview article

Cytoplasmic and Nuclear Receptors
Dendritic Cells
Genes
Genome
Lipids

Potential therapeutic use of PPARγ-programed human monocyte-derived dendritic cells in cancer vaccination therapy

Gyöngyösi, A. & Nagy, L., Nov 18 2008, In : PPAR Research. 473804.

Research output: Contribution to journalReview article

PPAR gamma
Therapeutic Uses
Dendritic Cells
Monocytes
Vaccination

The many faces of PPARγ: Anti-inflammatory by any means?

Szanto, A. & Nagy, L., Nov 6 2008, In : Immunobiology. 213, 9-10, p. 789-803 15 p.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Anti-Inflammatory Agents
Ligands
Cytoplasmic and Nuclear Receptors
Prostaglandins
2007

PPARγ in immunity and inflammation: cell types and diseases

Széles, L., Töröcsik, D. & Nagy, L., Aug 1 2007, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1771, 8, p. 1014-1030 17 p.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Immunity
Inflammation
Lipid Metabolism
Immune System
2006

Selective modulators of PPAR activity as new therapeutic tools in metabolic diseases

Balint, B. L. & Nagy, L., Jan 1 2006, In : Endocrine, Metabolic and Immune Disorders - Drug Targets. 6, 1, p. 33-43 11 p.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Metabolic Diseases
Ligands
Therapeutics
Selective Estrogen Receptor Modulators
2004

Mechanism of the nuclear receptor molecular switch

Nagy, L. & Schwabe, J. W. R., Jun 1 2004, In : Trends in Biochemical Sciences. 29, 6, p. 317-324 8 p.

Research output: Contribution to journalReview article

Cytoplasmic and Nuclear Receptors
Switches
Ligands
Transcription
Metabolism

Review retinoid x receptors: X-ploring their (patho)physiological functions

Szanto, A., Narkar, V., Shen, Q., Uray, I. P., Davies, P. J. A. & Nagy, L., Jan 1 2004, In : Cell Death and Differentiation. 11, p. S126-S143

Research output: Contribution to journalReview article

Retinoid X Receptors
Cytoplasmic and Nuclear Receptors
Transcription Factors
Ligands
Atherosclerosis
2003

The retinoid X receptor and its ligands: Versatile regulators of metabolic function, cell differentiation and cell death

Ahuja, H. S., Szanto, A., Nagy, L. & Davies, P. J. A., Jan 1 2003, In : Journal of Biological Regulators and Homeostatic Agents. 17, 1, p. 29-45 17 p.

Research output: Contribution to journalReview article

Retinoid X Receptors
Cell Differentiation
Cell Death
Ligands
Cytoplasmic and Nuclear Receptors
1999

Regulation of macrophage gene expression by peroxisome-proliferator-activated receptor γ: Implications for cardiovascular disease

Tontonoz, P. & Nagy, L., Dec 1 1999, In : Current Opinion in Lipidology. 10, 6, p. 485-490 6 p.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Macrophages
Gene Expression Regulation
Gene expression
Cardiovascular Diseases
1998

Retinoid-induced apoptosis in normal and neoplastic tissues

Nagy, L., Thomazy, V. A., Heyman, R. A. & Davies, P. J. A., Jan 1 1998, In : Cell Death and Differentiation. 5, 1, p. 11-19 9 p.

Research output: Contribution to journalReview article

Retinoids
Apoptosis
Molecular Probes
Bone Development
Tumor Cell Line
1994

Transglutaminases: Effector molecules in physiologic cell death

Nagy, L., Thomazy, V. & Davies, P. J. A., Jan 1 1994, In : Cancer Bulletin. 46, 2, p. 136-140 5 p.

Research output: Contribution to journalReview article

Transglutaminases
Keratinocytes
Cell Death
Enzymes
Epidermis