Laszlo Nagy

Professor

1991 …2019
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Research Output 1991 2019

2019

Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration

Giannakis, N., Sansbury, B. E., Patsalos, A., Hays, T. T., Riley, C. O., Han, X., Spite, M. & Nagy, L., May 1 2019, In : Nature Immunology. 20, 5, p. 626-636 11 p.

Research output: Contribution to journalArticle

Regeneration
Macrophages
Lipids
Muscles
Lipoxins

Gene expression analysis of vascular pathophysiology related to anti-TNF treatment in rheumatoid arthritis

Póliska, S., Besenyei, T., Végh, E., Hamar, A., Pusztai, A., Váncsa, A., Bodnár, N., Szamosi, S., Csumita, M., Kerekes, G., Szabó, Z., Nagy, Z., Szucs, G., Szántó, S., Zahuczky, G., Nagy, L. & Szekanecz, Z., Apr 15 2019, In : Arthritis Research and Therapy. 21, 1, 94.

Research output: Contribution to journalArticle

Open Access
Blood Vessels
Rheumatoid Arthritis
Tumor Necrosis Factor-alpha
Gene Expression
Pulse Wave Analysis

Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis

Puchalska, P., Martin, S. E., Huang, X., Lengfeld, J. E., Daniel, B., Graham, M. J., Han, X., Nagy, L., Patti, G. J. & Crawford, P. A., Feb 5 2019, In : Cell Metabolism. 29, 2, p. 383-398.e7

Research output: Contribution to journalArticle

Hepatocytes
Fibrosis
Macrophages
Coenzyme A-Transferases
Keto Acids

Identification and characterization of a novel anti-inflammatory lipid isolated from Mycobacterium vaccae, a soil-derived bacterium with immunoregulatory and stress resilience properties

Smith, D. G., Martinelli, R., Besra, G. S., Illarionov, P. A., Szatmari, I., Brazda, P., Allen, M. A., Xu, W., Wang, X., Nagy, L., Dowell, R. D., Rook, G. A. W., Rosa Brunet, L. & Lowry, C. A., Jan 1 2019, In : Psychopharmacology.

Research output: Contribution to journalArticle

PPAR alpha
Mycobacterium
Anti-Inflammatory Agents
Soil
Bacteria

Labelled regulatory elements are pervasive features of the macrophage genome and are dynamically utilized by classical and alternative polarization signals

Horvath, A., Daniel, B., Szeles, L., Cuaranta-Monroy, I., Czimmerer, Z., Ozgyin, L., Steiner, L., Kiss, M., Simandi, Z., Poliska, S., Giannakis, N., Raineri, E., Gut, I. G., Nagy, B. & Nagy, L., Apr 8 2019, In : Nucleic acids research. 47, 6, p. 2778-2792 15 p.

Research output: Contribution to journalArticle

Open Access
Chromatin
Macrophages
Genome
Transcription Factors
Gene Expression

Publisher Correction: Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration (Nature Immunology, (2019), 20, 5, (626-636), 10.1038/s41590-019-0356-7)

Giannakis, N., Sansbury, B. E., Patsalos, A., Hays, T. T., Riley, C. O., Han, X., Spite, M. & Nagy, L., Jan 1 2019, In : Nature Immunology.

Research output: Contribution to journalComment/debate

Open Access
Allergy and Immunology
Regeneration
Macrophages
Lipids
Muscles

Signal integration of IFN-I and IFN-II with TLR4 involves sequential recruitment of STAT1-Complexes and NFκB to enhance pro-inflammatory transcription

Piaszyk-Borychowska, A., Széles, L., Csermely, A., Chiang, H. C., Wesoły, J., Lee, C. K., Nagy, L. & Bluyssen, H. A. R., Jan 1 2019, In : Frontiers in immunology. 10, JUN, 1253.

Research output: Contribution to journalArticle

Open Access
Interferons
Blood Vessels
Response Elements
STAT1 Transcription Factor
Genes

The BACH1-HMOX1 regulatory axis is indispensable for proper macrophage subtype specification and skeletal muscle regeneration

Patsalos, A., Tzerpos, P., Halasz, L., Nagy, G., Pap, A., Giannakis, N., Lyroni, K., Koliaraki, V., Pintye, E., Dezso, B., Kollias, G., Spilianakis, C. G. & Nagy, L., Sep 15 2019, In : Journal of Immunology. 203, 6, p. 1532-1547 16 p.

Research output: Contribution to journalArticle

Regeneration
Skeletal Muscle
Macrophages
Phenotype
Heme
2018

A pharmacogenetic approach to the treatment of patients with PPARG mutations

Agostini, M., Schoenmakers, E., Beig, J., Fairall, L., Szatmari, I., Rajanayagam, O., Muskett, F. W., Adams, C., Marais, A. D., O’Rahilly, S., Semple, R. K., Nagy, L., Majithia, A. R., Schwabe, J. W. R., Blom, D. J., Murphy, R., Chatterjee, K. & Savage, D. B., Jun 1 2018, In : Diabetes. 67, 6, p. 1086-1092 7 p.

Research output: Contribution to journalArticle

Peroxisomes
Pharmacogenetics
Familial Partial Lipodystrophy
Mutation
rosiglitazone

Arginine methyltransferase PRMT8 provides cellular stress tolerance in aging motoneurons

Simandi, Z., Pajer, K., Karolyi, K., Sieler, T., Jiang, L. L., Kolostyak, Z., Sari, Z., Fekecs, Z., Pap, A., Patsalos, A., Contreras, G. A., Reho, B., Papp, Z., Guo, X., Horvath, A., Kiss, G., Keresztessy, Z., Vámosi, G., Hickman, J., Xu, H. & 5 others, Dormann, D., Hortobagyi, T., Antal, M., Nógrádi, A. & Nagy, L., Aug 29 2018, In : Journal of Neuroscience. 38, 35, p. 7683-7700 18 p.

Research output: Contribution to journalArticle

Protein-Arginine N-Methyltransferases
Motor Neurons
Cyclic AMP Response Element-Binding Protein
Knockout Mice
Arginine

CLA-supplemented diet accelerates experimental colorectal cancer by inducing TGF-β-producing macrophages and T cells

Moreira, T. G., Horta, L. S., Gomes-Santos, A. C., Oliveira, R. P., Queiroz, N. M. G. P., Mangani, D., Daniel, B., Vieira, A. T., Liu, S., Rodrigues, A. M., Gomes, D. A., Gabriely, G., Ferreira, E., Weiner, H. L., Rezende, R. M., Nagy, L. & Faria, A. M. C., Jan 1 2018, (Accepted/In press) In : Mucosal Immunology.

Research output: Contribution to journalArticle

Conjugated Linoleic Acids
Colorectal Neoplasms
Peroxisome Proliferator-Activated Receptors
Macrophages
Diet

Consumption of conjugated linoleic acid (CLA)-supplemented diet during colitis development ameliorates gut inflammation without causing steatosis in mice

Moreira, T. G., Gomes-Santos, A. C., Horta, L. S., Goncalves, M. C., Santiago, A. F., Lauar, J. G., dos Reis, D. S., Castro-Junior, A. B., Lemos, L., Guimarães, M., Aguilar, E. C., Pap, A., Amaral, J. F., Alvarez-Leite, J. I., Cara, D. C., Rezende, R. M., Nagy, L., Faria, A. M. C. & Maioli, T. U., Jul 1 2018, In : Journal of Nutritional Biochemistry. 57, p. 238-245 8 p.

Research output: Contribution to journalArticle

Conjugated Linoleic Acids
Colitis
Nutrition
Diet
Inflammation

Dynamic transcriptional control of macrophage miRNA signature via inflammation responsive enhancers revealed using a combination of next generation sequencing-based approaches

Czimmerer, Z., Horvath, A., Daniel, B., Nagy, G., Cuaranta-Monroy, I., Kiss, M., Kolostyak, Z., Poliska, S., Steiner, L., Giannakis, N., Varga, T. & Nagy, L., Jan 1 2018, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1861, 1, p. 14-28 15 p.

Research output: Contribution to journalArticle

Macrophages
MicroRNAs
Inflammation
Chromatin
Transcription Factor RelA

Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages

Czimmerer, Z., Nagy, Z. S., Nagy, G., Horvath, A., Silye-Cseh, T., Kriston, A., Jonas, D., Sauer, S., Steiner, L., Daniel, B., Deleuze, J. F. & Nagy, L., Aug 15 2018, In : Molecular and Cellular Endocrinology. 471, p. 63-74 12 p.

Research output: Contribution to journalArticle

Retinoid X Receptors
Macrophages
Interleukin-4
Genes
Genome

In vivo GDF3 administration abrogates aging related muscle regeneration delay following acute sterile injury

Patsalos, A., Simandi, Z., Hays, T. T., Peloquin, M., Hajian, M., Restrepo, I., Coen, P. M., Russell, A. J. & Nagy, L., Jan 1 2018, (Accepted/In press) In : Aging Cell.

Research output: Contribution to journalArticle

Growth Differentiation Factor 3
Regeneration
Macrophages
Muscles
Wounds and Injuries

Liver X receptor nuclear receptors are transcriptional regulators of dendritic cell chemotaxis

Beceiro, S., Pap, A., Czimmerer, Z., Sallam, T., Guillén, J. A., Gallardo, G., Hong, C., A-Gonzalez, N., Tabraue, C., Diaz, M., Lopez, F., Matalong, J., Valledor, A. F., Dominguez, P., Ardavin, C., Delgado-Martin, C., Partida-Sanchez, S., Rodriguez-Fernandez, J. L., Nagy, L., Tontono, P. & 1 others, Castrillo, A., May 1 2018, In : Molecular and Cellular Biology. 38, 10, e00534.

Research output: Contribution to journalArticle

Chemotaxis
Cytoplasmic and Nuclear Receptors
Dendritic Cells
LDL Receptors
Myeloid Cells

RXR heterodimers orchestrate transcriptional control of neurogenesis and cell fate specification

Simandi, Z., Horvath, A., Cuaranta-Monroy, I., Sauer, S., Deleuze, J. F. & Nagy, L., Aug 15 2018, In : Molecular and Cellular Endocrinology. 471, p. 51-62 12 p.

Research output: Contribution to journalArticle

Retinoid X Receptors
Neurogenesis
Specifications
Retinoic Acid Receptors
Embryonic Stem Cells

The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages

Daniel, B., Nagy, G., Horvath, A., Czimmerer, Z., Cuaranta-Monroy, I., Poliska, S., Hays, T. T., Sauer, S., Francois-Deleuze, J. & Nagy, L., May 1 2018, In : Nucleic acids research. 46, 9, p. 4425-4439 15 p.

Research output: Contribution to journalArticle

Open Access
Retinoid X Receptors
Peroxisome Proliferator-Activated Receptors
Interleukin-4
Macrophages
Ligands

The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory

Daniel, B., Nagy, G., Czimmerer, Z., Horvath, A., Hammers, D. W., Cuaranta-Monroy, I., Poliska, S., Tzerpos, P., Kolostyak, Z., Hays, T. T., Patsalos, A., Houtman, R., Sauer, S., Francois-Deleuze, J., Rastinejad, F., Balint, B. L., Sweeney, H. L. & Nagy, L., Oct 16 2018, In : Immunity. 49, 4, p. 615-626.e6

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Cytoplasmic and Nuclear Receptors
Epigenomics
Macrophages
Ligands

The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages

Czimmerer, Z., Daniel, B., Horvath, A., Rückerl, D., Nagy, G., Kiss, M., Peloquin, M., Budai, M. M., Cuaranta-Monroy, I., Simandi, Z., Steiner, L., Nagy, B., Poliska, S., Banko, C., Bacso, Z., Schulman, I. G., Sauer, S., Deleuze, J. F., Allen, J. E., Benko, S. & 1 others, Nagy, L., Jan 16 2018, In : Immunity. 48, 1, p. 75-90.e6

Research output: Contribution to journalArticle

STAT6 Transcription Factor
Interleukin-4
Macrophages
Inflammasomes
Interleukin-1

Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA

Sallam, T., Jones, M., Thomas, B. J., Wu, X., Gilliland, T., Qian, K., Eskin, A., Casero, D., Zhang, Z., Sandhu, J., Salisbury, D., Rajbhandari, P., Civelek, M., Hong, C., Ito, A., Liu, X., Daniel, B., Lusis, A. J., Whitelegge, J., Nagy, L. & 3 others, Castrillo, A., Smale, S. & Tontonoz, P., Mar 1 2018, In : Nature Medicine. 24, 3, p. 304-312 9 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Macrophages
Cytoplasmic and Nuclear Receptors
Atherosclerosis
Cholesterol
2017

A szkizofrénia multilókusz genetikai vizsgálata az idegfejlödés és az immunrendszer zavarának oki szerepére utal(hat)

Translated title of the contribution: Multilocus genetic analysis implicates neurodevelopment and immune system in the etiology of schizophreniaPulay, A. J., Koller, J., Nagy, L., Molnár, M. J. & Réthelyi, J., Mar 30 2017, In : Ideggyogyaszati Szemle. 70, 3-4, p. 115-126 12 p.

Research output: Contribution to journalArticle

Immune System
Schizophrenia
Cluster Analysis
Multifactorial Inheritance
Neuronal Plasticity

Immunity meets metabolism and then they start talking

Nagy, L. & Ellmeier, W., Oct 1 2017, In : FEBS Letters. 591, 19, p. 2957-2958 2 p.

Research output: Contribution to journalEditorial

T-cells
Macrophages
Metabolism
Animals

In situ macrophage phenotypic transition is affected by altered cellular composition prior to acute sterile muscle injury

Patsalos, A., Pap, A., Varga, T., Trencsenyi, G., Contreras, G. A., Garai, I., Papp, Z., Dezso, B., Pintye, E. & Nagy, L., Sep 1 2017, In : Journal of Physiology. 595, 17, p. 5815-5842 28 p.

Research output: Contribution to journalArticle

Macrophages
Muscles
Wounds and Injuries
Regeneration
Myeloid Cells

Interactions of retinoids with the ABC transporters P-glycoprotein and Breast Cancer Resistance Protein

Tarapcsák, S., Szalóki, G., Telbisz, Á., Gyöngy, Z., Matúz, K., Csosz, É., Nagy, P., Holb, I. J., Rühl, R., Nagy, L., Szabó, G. & Goda, K., Feb 1 2017, In : Scientific Reports. 7, 41376.

Research output: Contribution to journalArticle

Isotretinoin
ATP-Binding Cassette Transporters
Retinoids
P-Glycoprotein
Breast Neoplasms

Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function

Bermudez, B., Dahl, T. B., Medina, I., Groeneweg, M., Holm, S., Montserrat-De La Paz, S., Rousch, M., Otten, J., Herias, V., Varela, L. M., Ranheim, T., Yndestad, A., Ortega-Gomez, A., Abia, R., Nagy, L., Aukrust, P., Muriana, F. J. G., Halvorsen, B. & Biessen, E. A. L., Jun 1 2017, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 37, 6, p. 1157-1167 11 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Nicotinamide Phosphoribosyltransferase
Monocytes
Atherosclerosis
Leukocytes

MSTO1 is a cytoplasmic pro-mitochondrial fusion protein, whose mutation induces myopathy and ataxia in humans

Gal, A., Balicza, P., Weaver, D., Naghdi, S., Joseph, S. K., Várnai, P., Gyuris, T., Horváth, A., Nagy, L., Seifert, E. L., Molnar, M. J. & Hajnóczky, G., Jul 1 2017, In : EMBO Molecular Medicine. 9, 7, p. 967-984 18 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Mitochondrial Proteins
Muscular Diseases
Ataxia
Mitochondria

Nucleosome stability measured in situ by automated quantitative imaging

Imre, L., Simándi, Z., Horváth, A., Fenyofalvi, G., Nánási, P., Niaki, E. F., Hegedüs, É., Bacsó, Z., Weyemi, S., Mauser, R., Ausio, J., Jeltsch, A., Bonner, W., Nagy, L., Kimura, H. & Szabó, G., Dec 1 2017, In : Scientific Reports. 7, 1, 12734.

Research output: Contribution to journalArticle

Nucleosomes
Histones
Intercalating Agents
Chromatin
DNA

Retinoid X receptor suppresses a metastasis-promoting transcriptional program in myeloid cells via a ligand-insensitive mechanism

Kiss, M., Czimmerer, Z., Nagy, G., Bieniasz-Krzywiec, P., Ehling, M., Pap, A., Poliska, S., Boto, P., Tzerpos, P., Horvath, A., Kolostyak, Z., Daniel, B., Szatmari, I., Mazzone, M. & Nagy, L., Oct 3 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 40, p. 10725-10730 6 p.

Research output: Contribution to journalArticle

Retinoid X Receptors
Myeloid Cells
Neoplasm Metastasis
Ligands
Nuclear Receptor Co-Repressor 2

Titin isoforms are increasingly protected against oxidative modifications in developing rat cardiomyocytes

Bódi, B., Tóth, E. P., Nagy, L., Tóth, A., Mártha, L., Kovács, Á., Balla, G., Kovács, T. & Papp, Z., Dec 1 2017, In : Free Radical Biology and Medicine. 113, p. 224-235 12 p.

Research output: Contribution to journalArticle

Connectin
Cardiac Myocytes
Rats
Protein Isoforms
Carbonylation

Transcriptional complexes as functional agents: Getting in touch with the genome requires teamwork at multiple levels

Horvath, A., Simandi, Z. & Nagy, L., Oct 1 2017, In : Journal of Applied Physiology. 123, 4, 1 p.

Research output: Contribution to journalComment/debate

Genome
2016

Decreased peroxisome proliferator-activated receptor γ level and signalling in sebaceous glands of patients with acne vulgaris

Dozsa, A., Mihaly, J., Dezso, B., Csizmadia, E., Keresztessy, T., Marko, L., Rühl, R., Remenyik, E. & Nagy, L., Jul 1 2016, In : Clinical and Experimental Dermatology. 41, 5, p. 547-551 5 p.

Research output: Contribution to journalArticle

Sebaceous Glands
Peroxisome Proliferator-Activated Receptors
Acne Vulgaris
Lipid Metabolism
Lipids

Differentiation of adipocytes in monolayer from mouse embryonic stem cells

Cuaranta-Monroy, I., Simandi, Z. & Nagy, L., Oct 1 2016, Methods in Molecular Biology. Humana Press Inc., p. 407-415 9 p. (Methods in Molecular Biology; vol. 1341).

Research output: Chapter in Book/Report/Conference proceedingChapter

Adipocytes
Pluripotent Stem Cells
Embryonic Stem Cells
Comorbidity
Obesity

Highly dynamic transcriptional signature of distinct macrophage subsets during sterile inflammation, resolution, and tissue repair

Varga, T., Mounier, R., Horvath, A., Cuvellier, S., Dumont, F., Poliska, S., Ardjoune, H., Juban, G., Nagy, L. & Chazaud, B., Jun 1 2016, In : Journal of Immunology. 196, 11, p. 4771-4782 12 p.

Research output: Contribution to journalArticle

Macrophages
Inflammation
Gene Expression
Regeneration
Citric Acid Cycle

Is the mouse a good model of human PPARγ-related metabolic diseases?

Pap, A., Cuaranta-Monroy, I., Peloquin, M. & Nagy, L., Aug 1 2016, In : International Journal of Molecular Sciences. 17, 8, 1236.

Research output: Contribution to journalReview article

metabolic diseases
PPAR gamma
Metabolic Diseases
mice
Human Experimentation

Macrophage PPARγ, a Lipid Activated Transcription Factor Controls the Growth Factor GDF3 and Skeletal Muscle Regeneration

Varga, T., Mounier, R., Patsalos, A., Gogolák, P., Peloquin, M., Horvath, A., Pap, A., Daniel, B., Nagy, G., Pintye, E., Poliska, S., Cuvellier, S., Ben Larbi, S., Sansbury, B. E., Spite, M., Brown, C. W., Chazaud, B. & Nagy, L., Nov 15 2016, In : Immunity. 45, 5, p. 1038-1051 14 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Regeneration
Intercellular Signaling Peptides and Proteins
Skeletal Muscle
Transcription Factors

Motif oriented high-resolution analysis of ChIP-seq data reveals the topological order of CTCF and cohesin proteins on DNA

Nagy, G., Czipa, E., Steiner, L., Nagy, T., Pongor, S., Nagy, L. & Barta, E., Aug 15 2016, In : BMC Genomics. 17, 1, 637.

Research output: Contribution to journalArticle

DNA
Proteins
DNA-Binding Proteins
Transcription Factors
Genome

Nuclear Receptors in Immune Function

Kiss, M. & Nagy, L., Apr 27 2016, Activation of the Immune System. Elsevier Inc., Vol. 3. p. 146-156 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cytoplasmic and Nuclear Receptors
Lipids
Gene Expression
Dendritic Cells
Chronic Disease

OCT4 Acts as an Integrator of Pluripotency and Signal-Induced Differentiation

Simandi, Z., Horvath, A., Wright, L. C., Cuaranta-Monroy, I., De Luca, I., Karolyi, K., Sauer, S., Deleuze, J. F., Gudas, L. J., Cowley, S. M. & Nagy, L., Aug 18 2016, In : Molecular Cell. 63, 4, p. 647-661 15 p.

Research output: Contribution to journalArticle

Transcription Factors
Catenins
Genetic Models
Embryonic Stem Cells
Transcriptional Activation

ORM-3819 promotes cardiac contractility through Ca2+ sensitization in combination with selective PDE III inhibition, a novel approach to inotropy

Nagy, L., Pollesello, P., Haikala, H., Végh, Á., Sorsa, T., Levijoki, J., Szilágyi, S., Édes, I., Tóth, A., Papp, Z. & Papp, J. G., Mar 15 2016, In : European Journal of Pharmacology. 775, p. 120-129 10 p.

Research output: Contribution to journalArticle

Heart Ventricles
Troponin C
Cardiotonic Agents
Guinea Pigs
Isoenzymes

Prediction and validation of gene regulatory elements activated during retinoic acid induced embryonic stem cell differentiation

Simandi, Z., Horvath, A., Nagy, P. & Nagy, L., Jun 21 2016, In : Journal of Visualized Experiments. 2016, 112, e53978.

Research output: Contribution to journalArticle

Chromatin Immunoprecipitation
Regulator Genes
Embryonic Stem Cells
Tretinoin
Stem cells

The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p

Czimmerer, Z., Varga, T., Kiss, M., V�zquez, C. O., Doan-Xuan, Q. M., R�ckerl, D., Tattikota, S. G., Yan, X., Nagy, Z. S., Daniel, B., Poliska, S., Horvath, A., Nagy, G., Varallyay, E., Poy, M., Allen, J. E., Bacso, Z., Abreu-Goodger, C. & Nagy, L., May 31 2016, In : Genome Medicine. 8, 1, 63.

Research output: Contribution to journalArticle

Macrophage Activation
MicroRNAs
Interleukin-4
Cell Survival
Macrophages
2015

9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice

Rühl, R., Krzyżosiak, A., Niewiadomska-Cimicka, A., Rochel, N., Szeles, L., Vaz, B., Wietrzych-Schindler, M., Álvarez, S., Szklenar, M., Nagy, L., de Lera, A. R. & Krężel, W., Jan 1 2015, In : PLoS Genetics. 11, 6, e1005213.

Research output: Contribution to journalArticle

Retinoid X Receptors
retinoids
Retinoids
ligand
Ligands

Combination of IgG N-glycomics and corresponding transcriptomics data to identify anti-TNF-α treatment responders in inflammatory diseases

Váradi, C., Holló, Z., Póliska, S., Nagy, L., Szekanecz, Z., Váncsa, A., Palatka, K. & Guttman, A., Jan 1 2015, In : Electrophoresis. 36, 11-12, p. 1330-1335 6 p.

Research output: Contribution to journalArticle

Glycomics
Necrosis
Immunoglobulin G
Crohn Disease
Polysaccharides

Erratum: PPARγ activation but not PPARγ haplodeficiency affects proangiogenic potential of endothelial cells and bone marrow-derived progenitors [Cardiovasc Diabetol 13, (2014), 150]

Kotlinowski, J., Grochot-Przeczek, A., Taha, H., Kozakowska, M., Pilecki, B., Skrzypek, K., Zimoch, J., Bartelik, A., Derlacz, R., Horrevoets, A. J., Pap, A., Nagy, L., Dulak, J. & Jozkowicz, A., May 29 2015, In : Cardiovascular Diabetology. 14, 1, 65.

Research output: Contribution to journalArticle

Tolbutamide
Endothelial Cells
Bone Marrow

Genomewide effects of peroxisome proliferator-activated receptor gamma in macrophages and dendritic cells - Revealing complexity through systems biology

Cuaranta-Monroy, I., Kiss, M., Simandi, Z. & Nagy, L., Sep 1 2015, In : European Journal of Clinical Investigation. 45, 9, p. 964-975 12 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Systems Biology
Macrophages
PPAR gamma
Dendritic Cells

Oral health-related quality of life after prosthetic rehabilitation: A longitudinal study with the OHIP questionnaire

Jenei, Á., Sándor, J., HegedUs, C., Bágyi, K., Nagy, L., Kiss, C., Szabó, G. & Márton, I. J., Jul 10 2015, In : Health and Quality of Life Outcomes. 13, 1, 99.

Research output: Contribution to journalArticle

Oral Health
Longitudinal Studies
Rehabilitation
Quality of Life
Dentures

PRMT1 and PRMT8 regulate retinoic acid-dependent neuronal differentiation with implications to neuropathology

Simandi, Z., Czipa, E., Horvath, A., Koszeghy, A., Bordas, C., Põliska, S., Juhász, I., Imre, L., Szabõ, G., Dezso, B., Barta, E., Sauer, S., Karolyi, K., Kovacs, I., Hutõczki, G., Bognár, L., Klekner, Á., Szucs, P., Bálint, B. L. & Nagy, L., Mar 1 2015, In : Stem Cells. 33, 3, p. 726-741 16 p.

Research output: Contribution to journalArticle

Retinoids
Tretinoin
Embryonic Stem Cells
Arginine
Genes

The novel cardiac myosin activator omecamtiv mecarbil increases the calcium sensitivity of force production in isolated cardiomyocytes and skeletal muscle fibres of the rat

Nagy, L., Kovács, Bõdi, B., Pásztor, E. T., Fülöp, G., Tõth, A., Édes, I. & Papp, Z., Sep 1 2015, In : British Journal of Pharmacology. 172, 18, p. 4506-4518 13 p.

Research output: Contribution to journalArticle

Cardiac Myosins
Skeletal Muscle Fibers
Cardiac Myocytes
Calcium
Diaphragm
2014

Causes and Pathophysiology of Heart Failure with Preserved Ejection Fraction

Kovács, Á., Papp, Z. & Nagy, L., Jan 1 2014, In : Heart Failure Clinics. 10, 3, p. 389-398 10 p.

Research output: Contribution to journalReview article

Diastolic Heart Failure
Systolic Heart Failure
Sex Distribution
Vascular Stiffness
Aortic Valve Stenosis