Lama Al-Qusairi

Research Associate

20092017
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Research Output 2009 2017

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Article
2017

Renal tubular ubiquitin-protein ligase NEDD4-2 is required for renal adaptation during long-term potassium depletion

Al-Qusairi, L., Basquin, D., Roy, A., Rajaram, R. D., Maillard, M. P., Subramanya, A. R. & Staub, O., Aug 2017, In : Journal of the American Society of Nephrology. 28, 8, p. 2431-2442 12 p.

Research output: Contribution to journalArticle

Open Access
Member 3 Solute Carrier Family 12
Ubiquitin-Protein Ligases
Potassium
Large-Conductance Calcium-Activated Potassium Channels
Kidney
2016

Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC

Al-Qusairi, L., Basquin, D., Roy, A., Stifanelli, M., Rajaram, R. D., Debonneville, A., Nita, I., Maillard, M., Loffing, J., Subramanya, A. R. & Staub, O., Aug 1 2016, In : American Journal of Physiology - Renal Physiology. 311, 2, p. F330-F342

Research output: Contribution to journalArticle

Epithelial Sodium Channels
Kidney
Phosphotransferases
Aldosterone
Nephrons
2015

Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action

Roy, A., Al-Qusairi, L., Donnelly, B. F., Ronzaud, C., Marciszyn, A. L., Gong, F., Christy Chang, Y. P., Butterworth, M. B., Pastor-Soler, N. M., Hallows, K. R., Staub, O. & Subramanya, A. R., Sep 1 2015, In : Journal of Clinical Investigation. 125, 9, p. 3433-3448 16 p.

Research output: Contribution to journalArticle

Aldosterone
Proline
Protein Isoforms
Phosphotransferases
Exons
2014

A primary culture system of mouse thick ascending limb cells with preserved function and uromodulin processing

Glaudemans, B., Terryn, S., Gölz, N., Brunati, M., Cattaneo, A., Bachi, A., Al-Qusairi, L., Ziegler, U., Staub, O., Rampoldi, L. & Devuyst, O., Feb 1 2014, In : Pflugers Archiv European Journal of Physiology. 466, 2, p. 343-356 14 p.

Research output: Contribution to journalArticle

Uromodulin
Extremities
Monolayers
Processing
Bumetanide

Congenital ataxia and hemiplegic migraine with cerebral edema associated with a novel gain of function mutation in the calcium channel CACNA1A

García Segarra, N., Gautschi, I., Mittaz-Crettol, L., Kallay Zetchi, C., Al-Qusairi, L., Van Bemmelen, M. X., Maeder, P., Bonafé, L., Schild, L. & Roulet-Perez, E., Jul 15 2014, In : Journal of the Neurological Sciences. 342, 1-2, p. 69-78 10 p.

Research output: Contribution to journalArticle

Brain Edema
Ataxia
Calcium Channels
Migraine Disorders
Spinocerebellar Ataxias
2013

Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathways

Al-Qusairi, L., Prokic, I., Amoasii, L., Kretz, C., Messaddeq, N., Mandel, J. L. & Laporte, J., Aug 1 2013, In : FASEB Journal. 27, 8, p. 3384-3394 11 p.

Research output: Contribution to journalArticle

Congenital Structural Myopathies
Autophagy
Proteasome Endopeptidase Complex
Ubiquitin
Muscle
2009

T-tubule disorganization and defective excitation-contraction coupling in muscle fibers lacking myotubularin lipid phosphatase

Al-Qusairi, L., Weiss, N., Toussaint, A., Berbey, C., Messaddeq, N., Kretz, C., Sanoudou, D., Beggs, A. H., Allard, B., Mandel, J. L., Laporte, J., Jacquemond, V. & Buj-Bello, A., Nov 3 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 44, p. 18763-18768 6 p.

Research output: Contribution to journalArticle

Excitation Contraction Coupling
Sarcoplasmic Reticulum
Phosphoric Monoester Hydrolases
Ryanodine Receptor Calcium Release Channel
Congenital Structural Myopathies