King-Wai Yau

Professor

1976 …2020

Research output per year

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Research Output

2005

Breaking the covalent bond - A pigment property that contributes to desensitization in cones

Kefalov, V. J., Estevez, M. E., Kono, M., Goletz, P. W., Crouch, R. K., Cornwall, M. C. & Yau, K. W., Jun 16 2005, In : Neuron. 46, 6, p. 879-890 12 p.

Research output: Contribution to journalArticle

Cell signaling: Elementary response of olfactory receptor neurons to odorants

Bhandawat, V., Reisert, J. & Yau, K. W., Jun 24 2005, In : Science. 308, 5730, p. 1931-1934 4 p.

Research output: Contribution to journalArticle

Farnesylation of retinal transducin underlies its translocation during light adaptation

Kassai, H., Aiba, A., Nakao, K., Nakamura, K., Katsuki, M., Xiong, W. H., Yau, K. W., Imai, H., Shichida, Y., Satomi, Y., Takao, T., Okano, T. & Fukada, Y., Aug 18 2005, In : Neuron. 47, 4, p. 529-539 11 p.

Research output: Contribution to journalArticle

Impaired channel targeting and retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGB1

Hüttl, S., Michalakis, S., Seeliger, M., Luo, D. G., Acar, N., Geiger, H., Hudl, K., Mader, R., Haverkamp, S., Moser, M., Pfeifer, A., Gerstner, A., Yau, K. W. & Biel, M., Jan 5 2005, In : Journal of Neuroscience. 25, 1, p. 130-138 9 p.

Research output: Contribution to journalArticle

Intrinsically photosensitive retinal ganglion cells detect light with a vitamin A-based photopigment, melanopsin

Fu, Y., Zhong, H., Wang, M. H. H., Luo, D. G., Liao, H. W., Maeda, H., Hattar, S., Frishman, L. J. & Yau, K. W., Jul 19 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 29, p. 10339-10344 6 p.

Research output: Contribution to journalArticle

Mechanism of the excitatory Cl- response in mouse olfactory receptor neurons

Reisert, J., Lai, J., Yau, K. W. & Bradley, J., Feb 17 2005, In : Neuron. 45, 4, p. 553-561 9 p.

Research output: Contribution to journalArticle

Melanopsin-dependent photoreception provides earliest light detection in the mammalian retina

Sekaran, S., Lupi, D., Jones, S. L., Sheely, C. J., Hattar, S., Yau, K. W., Lucas, R. J., Foster, R. G. & Hankins, M. W., Jun 21 2005, In : Current Biology. 15, 12, p. 1099-1107 9 p.

Research output: Contribution to journalArticle

Melanopsin-expressing ganglion cells in primate retina signal colour and irradiance and project to the LGN

Dacey, D. M., Liao, H. W., Peterson, B. B., Robinson, F. R., Smith, V. C., Pokomy, J., Yau, K. W. & Gamlin, P. D., Feb 17 2005, In : Nature. 433, 7027, p. 749-754 6 p.

Research output: Contribution to journalArticle

Non-image-forming ocular photoreception in vertebrates

Fu, Y., Liao, H. W., Do, M. T. H. & Yau, K. W., Aug 1 2005, In : Current Opinion in Neurobiology. 15, 4, p. 415-422 8 p.

Research output: Contribution to journalReview article

Rod sensitivity of neonatal mouse and rat

Luo, D. G. & Yau, K. W., Sep 1 2005, In : Journal of General Physiology. 126, 3, p. 263-269 7 p.

Research output: Contribution to journalArticle

2004

Calmodulin permanently associates with rat olfactory CNG channels under native conditions

Bradley, J., Bönigk, W., Yau, K. W. & Frings, S., Jul 1 2004, In : Nature neuroscience. 7, 7, p. 705-710 6 p.

Research output: Contribution to journalArticle

PHR1, a PH domain-containing protein expressed in primary sensory neurons

Xu, S., Wang, Y., Zhao, H., Zhang, L., Xiong, W., Yau, K. W., Hiel, H., Glowatzki, E., Ryugo, D. K. & Valle, D., Oct 1 2004, In : Molecular and cellular biology. 24, 20, p. 9137-9151 15 p.

Research output: Contribution to journalArticle

2003

Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice

Lucas, R. J., Hattar, S., Takao, M., Berson, D. M., Foster, R. G. & Yau, K. W., Jan 10 2003, In : Science. 299, 5604, p. 245-247 3 p.

Research output: Contribution to journalArticle

Melanopsin and rod—cone photoreceptive systems account for all major accessory visual functions in mice

Hattar, S., Lucas, R. J., Mrosovsky, N., Thompson, S., Douglas, R. H., Hankins, M. W., Lem, J., Biel, M., Hofmann, F., Foster, R. G. & Yau, K. W., Jul 3 2003, In : Nature. 424, 6944, p. 76-81 6 p.

Research output: Contribution to journalLetter

Role of visual pigment properties in rod and cone phototransduction

Kefalov, V., Fu, Y., Marsh-Amstrong, N. & Yau, K. W., Oct 2 2003, In : Nature. 425, 6957, p. 526-531 6 p.

Research output: Contribution to journalArticle

Selective heteromeric assembly of cyclic nucleotide-gated channels

Zhong, H., Lai, J. & Yau, K. W., Apr 29 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 9, p. 5509-5513 5 p.

Research output: Contribution to journalArticle

Sensory systems

Reid, R. C. & Yau, K. W., Aug 2003, In : Current Opinion in Neurobiology. 13, 4, p. 401-403 3 p.

Research output: Contribution to journalEditorial

Structure-Function Analysis of the Bestrophin Family of Anion Channels

Tsunenari, T., Sun, H., Williams, J., Cahill, H., Smallwood, P., Yau, K. W. & Nathans, J., Oct 17 2003, In : Journal of Biological Chemistry. 278, 42, p. 41114-41125 12 p.

Research output: Contribution to journalArticle

The Ca-activated Cl channel and its control in rat olfactory receptor neurons

Reisert, J., Bauer, P. J., Yau, K. W. & Frings, S., Sep 1 2003, In : Journal of General Physiology. 122, 3, p. 349-363 15 p.

Research output: Contribution to journalArticle

2002

Calcium and phototransduction

Nakatani, K., Chen, C., Yau, K. W. & Koutalos, Y., Dec 1 2002, In : Advances in experimental medicine and biology. 514, p. 1-20 20 p.

Research output: Contribution to journalArticle

Melanopsin-containing retinal ganglion cells: Architecture, projections, and intrinsic photosensitivity

Hattar, S., Liao, H. W., Takao, M., Berson, D. M. & Yau, K. W., Feb 8 2002, In : Science. 295, 5557, p. 1065-1070 6 p.

Research output: Contribution to journalArticle

Rod sensitivity during Xenopus development

Xiong, W. H. & Yau, K. W., Dec 1 2002, In : Journal of General Physiology. 120, 6, p. 817-827 11 p.

Research output: Contribution to journalArticle

The heteromeric cyclic nucleotide-gated channel adopts a 3A:1B stoichlometry

Zhong, H., Molday, L. L., Molday, R. S. & Yau, K. W., Nov 14 2002, In : Nature. 420, 6912, p. 193-198 6 p.

Research output: Contribution to journalArticle

The vitelliform macular dystrophy protein defines a new family of chloride channels

Sun, H., Tsunenari, T., Yau, K. W. & Nathans, J., Mar 19 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 6, p. 4008-4013 6 p.

Research output: Contribution to journalArticle

2001

Central role of the CNGA4 channel subunit in Ca2+-calmodulin-dependent odor adaptation

Munger, S. D., Lane, A. P., Zhong, H., Leinders-Zufall, T., Yau, K. W., Zufall, F. & Reed, R. R., Dec 7 2001, In : Science. 294, 5549, p. 2172-2175 4 p.

Research output: Contribution to journalArticle

Nomenclature for ion channel subunits [4]

Bradley, J., Frings, S., Yau, K. W. & Reed, R., Dec 7 2001, In : Science. 294, 5549, p. 2095-2096 2 p.

Research output: Contribution to journalLetter

Normal light response, photoreceptor integrity, and rhodopsin dephosphorylation in mice lacking both protein phosphatases with ef hands (PPEF-1 and PPEF-2)

Ramulu, P., Kennedy, M., Xiong, W. H., Williams, J., Cowan, M., Blesh, D., Yau, K. W., Hurley, J. B. & Nathans, J., Dec 13 2001, In : Molecular and cellular biology. 21, 24, p. 8605-8614 10 p.

Research output: Contribution to journalArticle

2000

Characterization of guanylyl cyclase and phosphodiesterase activities in single rod outer segments

Koutalos, Y. & Yau, K. W., Jan 1 2000, In : Methods in enzymology. 315, p. 742-752 11 p.

Research output: Contribution to journalReview article

Isolation and in vitro differentiation of conditionally immortalized murine olfactory receptor neurons

Barber, R. D., Jaworsky, D. E., Yau, K. W. & Ronnett, G. V., May 15 2000, In : Journal of Neuroscience. 20, 10, p. 3695-3704 10 p.

Research output: Contribution to journalArticle

Modulation of rod cGMP-gated cation channel by calmodulin

Grunwald, M. E. & Yau, K. W., Jan 1 2000, In : Methods in enzymology. 315, p. 817-828 12 p.

Research output: Contribution to journalReview article

1999

Disruption of a retinal guanylyl cyclase gene leads to cone-specific dystrophy and paradoxical rod behavior

Yang, R. B., Robinson, S. W., Xiong, W. H., Yau, K. W., Birch, D. G. & Garbers, D. L., Jul 15 1999, In : Journal of Neuroscience. 19, 14, p. 5889-5897 9 p.

Research output: Contribution to journalArticle

Molecular determinants of the modulation of cyclic nucleotide-activated channels by calmodulin

Grunwald, M. E., Zhong, H., Lai, J. & Yau, K. W., Nov 9 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 23, p. 13444-13449 6 p.

Research output: Contribution to journalArticle

1998

A cGMP-gated cation channel and phototransduction in depolarizing photoreceptors of the lizard parietal eye

Finn, J. T., Xiong, W. H., Solessio, E. C. & Yau, K. W., May 1 1998, In : Vision Research. 38, 10, p. 1353-1357 5 p.

Research output: Contribution to journalArticle

An unusual cGMP pathway underlying depolarizing light response of the vertebrate parietal-eye photoreceptor

Xiong, W. H., Solessio, E. C. & Yau, K-W., 1998, In : Molecular Cell. 1, 5, p. 359-365 7 p.

Research output: Contribution to journalArticle

Functional co-assembly among subunits of cyclic-nucleotide-activated, nonselective cation channels, and across species from nematode to human

Finn, J. T., Krautwurst, D., Schroeder, J. E., Chen, T. Y., Reed, R. R. & Yau, K. W., Mar 1998, In : Biophysical journal. 74, 3, p. 1333-1345 13 p.

Research output: Contribution to journalArticle

Open Access

Identification of a domain on the β-subunit of the rod cGMP-gated cation channel that mediates inhibition by calcium-calmodulin

Grunwald, M. E., Yu, W. P., Yu, H. H. & Yau, K. W., Apr 10 1998, In : Journal of Biological Chemistry. 273, 15, p. 9148-9157 10 p.

Research output: Contribution to journalArticle

Identification of ligands for olfactory receptors by functional expression of a receptor library

Krautwurst, D., Yau, K. W. & Reed, R. R., Dec 23 1998, In : Cell. 95, 7, p. 917-926 10 p.

Research output: Contribution to journalArticle

Introducing Robert S. Molday, the 1998 recipient of the Friedenwald Award

Yau, K. W., Jan 1 1998, In : Investigative Ophthalmology and Visual Science. 39, 13, p. 2491-2492 2 p.

Research output: Contribution to journalArticle

1997

A cGMP-gated cation channel in depolarizing photoreceptors of the lizard parietal eye

Finn, J. T., Solessio, E. C. & Yau, K. W., Feb 27 1997, In : Nature. 385, 6619, p. 815-819 5 p.

Research output: Contribution to journalArticle

Identification of components of a phosphoinositide signaling pathway in retinal rod outer segments

Peng, Y. W., Rhee, S. G., Yu, W. P., Ho, Y. K., Schoen, T., Chader, G. J. & Yau, K. W., Mar 4 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 5, p. 1995-2000 6 p.

Research output: Contribution to journalArticle

Phototransduction mechanism in depolarizing photoreceptors of lizard parietal eye

Xiong, W. H., Solessio, E. & Yau, K. W., Dec 1 1997, In : Investigative Ophthalmology and Visual Science. 38, 4, p. S24

Research output: Contribution to journalArticle

Protein kinase C activity and light sensitivity of dissociated salamander rods

Nakatani, K., Xiong, W. H., Ye, B. & Yau, K. W., Dec 1 1997, In : Investigative Ophthalmology and Visual Science. 38, 4, p. S24

Research output: Contribution to journalArticle

Protein kinase C activity and light sensitivity of single amphibian rods

Xiong, W. H., Nakatani, K., Ye, B. & Yau, K. W., Oct 1 1997, In : Journal of General Physiology. 110, 4, p. 441-452 12 p.

Research output: Contribution to journalArticle

1996

Cyclic nucleotide-gated ion channels: An extended family with diverse functions

Finn, J. T., Grunwald, M. E. & Yau, K. W., Jan 1 1996, In : Annual review of physiology. 58, p. 395-426 32 p.

Research output: Contribution to journalReview article

Molecular cloning, functional expression and chromosomal localization of a human homolog of the cyclic nucleotide-gated ion channel of retinal cone photoreceptors

Yu, W. P., Grunwald, M. E. & Yau, K. W., Sep 16 1996, In : FEBS Letters. 393, 2-3, p. 211-215 5 p.

Research output: Contribution to journalArticle

Regulation of sensitivity in vertebrate rod photoreceptors by calcium

Koutalos, Y. & Yau, K. W., Feb 1996, In : Trends in neurosciences. 19, 2, p. 73-81 9 p.

Research output: Contribution to journalReview article

1995

Ca2+ modulation of the cGMP‐gated channel of bullfrog retinal rod photoreceptors.

Nakatani, K., Koutalos, Y. & Yau, K. W., Apr 1 1995, In : The Journal of physiology. 484, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

Characterization of guanylate cyclase activity in single retinal rod outer segments

Koutalos, Y., Nakatani, K., Tamura, T. & Yau, K. W., Nov 1 1995, In : Journal of General Physiology. 106, 5, p. 863-890 28 p.

Research output: Contribution to journalArticle

Cyclic GMP diffusion coefficient in rod photoreceptor outer segments

Koutalos, Y., Nakatani, K. & Yau, K. W., Jan 1 1995, In : Biophysical journal. 68, 1, p. 373-382 10 p.

Research output: Contribution to journalArticle

Open Access

Diffusion coefficient of the cyclic GMP analog 8-(fluoresceinyl)thioguanosine 3',5' cyclic monophosphate in the salamander rod outer segment

Koutalos, Y., Brown, R. L., Karpen, J. W. & Yau, K. W., Jan 1 1995, In : Biophysical journal. 69, 5, p. 2163-2167 5 p.

Research output: Contribution to journalArticle

Open Access